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Accession Type:
Pathway
sGC_Stone_
Marletta
sGC

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Accession information for sGC_Stone_Marletta (Accession Number 15)

Reaction Scheme

Accession Basic Parameters

Name sGC_Stone_Marletta
Accession Type Pathway
Transcriber Sudhir Sivakumaran, NCBS
Developer Stone and Marletta, 1996.
Entry Date (YYYY-MM-DD) 2001-12-12
Species Bovine
Tissue Lungs
Cell Compartment Cytosol
Source Stone JR, Marletta MA. Biochemistry (1996) 35(4):1093-9. ( peer-reviewed publication )
Methodology Quantitative match to experiments
Model Implementation Mathematically equivalent
Model Validation Replicates orginal data
Notes This features the two step binding of NO to soluble Guanylyl Cyclase as proposed by Stone JR, Marletta MA. Biochemistry (1996) 35(4):1093-9. There is a fast step binding scheme and a slow step binding scheme. The difference lies in the binding of a NO to a non-heme site on sGC, which may not necessarily be the same site of binding during the initial binding. The rates have been directly used from their models

Conversion formats

FormatFile
Native Format (GENESIS format)    acc15.g   
GENESIS Format (Annotated version)    Anno_acc15.g   
MATLAB format    acc15.m   
SBML format    acc15.xml   



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