//genesis // kkit Version 11 flat dumpfile // Saved on Fri Dec 8 15:17:38 2006 include kkit {argv 1} FASTDT = 1e-05 SIMDT = 0.001 CONTROLDT = 10 PLOTDT = 1 MAXTIME = 5000 TRANSIENT_TIME = 2 VARIABLE_DT_FLAG = 1 DEFAULT_VOL = 1.2566e-16 VERSION = 11.0 setfield /file/modpath value /home2/bhalla/scripts/modules kparms //genesis initdump -version 3 -ignoreorphans 1 simobjdump doqcsinfo filename accessname accesstype transcriber developer \ citation species tissue cellcompartment methodology sources \ model_implementation model_validation x y z simobjdump table input output alloced step_mode stepsize x y z simobjdump xtree path script namemode sizescale simobjdump xcoredraw xmin xmax ymin ymax simobjdump xtext editable simobjdump xgraph xmin xmax ymin ymax overlay simobjdump xplot pixflags script fg ysquish do_slope wy simobjdump group xtree_fg_req xtree_textfg_req plotfield expanded movealone \ link savename file version md5sum mod_save_flag x y z simobjdump geometry size dim shape outside xtree_fg_req xtree_textfg_req x y \ z simobjdump kpool DiffConst CoInit Co n nInit mwt nMin vol slave_enable \ geomname xtree_fg_req xtree_textfg_req x y z simobjdump kreac kf kb notes xtree_fg_req xtree_textfg_req x y z simobjdump kenz CoComplexInit CoComplex nComplexInit nComplex vol k1 k2 k3 \ keepconc usecomplex notes xtree_fg_req xtree_textfg_req link x y z simobjdump stim level1 width1 delay1 level2 width2 delay2 baselevel trig_time \ trig_mode notes xtree_fg_req xtree_textfg_req is_running x y z simobjdump xtab input output alloced step_mode stepsize notes editfunc \ xtree_fg_req xtree_textfg_req baselevel last_x last_y is_running x y z simobjdump kchan perm gmax Vm is_active use_nernst notes xtree_fg_req \ xtree_textfg_req x y z simobjdump transport input output alloced step_mode stepsize dt delay clock \ kf xtree_fg_req xtree_textfg_req x y z simobjdump proto x y z simundump geometry /kinetics/dendgeom 0 1.5e-18 3 cylinder "" white black 8 \ -2 0 simundump group /kinetics/PKC 0 blue black x 0 0 "" defaultfile defaultfile.g \ 0 0 0 -3.0493 8.2163 0 simundump kpool /kinetics/PKC/PKC-Ca 0 -1e-12 0.078942 0.078942 5951.9 5951.9 \ 0 0 75396 4 /kinetics/dendgeom red black -4.0752 1.5108 0 simundump kreac /kinetics/PKC/PKC-Ca/diff 0 0.101 0.001 "" white black \ -3.0752 4.5108 0 simundump kreac /kinetics/PKC/PKC-act-by-Ca 0 7.958e-06 0.5 "" white blue \ -4.0752 -0.12295 0 simundump kreac /kinetics/PKC/PKC-act-by-DAG 0 1.061e-07 8.6348 "" white blue \ -2.0612 0.69395 0 simundump kreac /kinetics/PKC/PKC-Ca-to-memb 0 1.2705 3.5026 "" white blue \ -3.7974 4.2533 0 simundump kreac /kinetics/PKC/PKC-DAG-to-memb 0 1 0.1 "" white blue -2.6168 \ 2.7362 0 simundump kpool /kinetics/PKC/PKC-Ca-memb* 0 -1e-12 0.028634 0.028634 2158.9 \ 2158.9 0 0 75396 4 /kinetics/dendgeom pink blue -2.7788 6.529 0 simundump kreac /kinetics/PKC/PKC-Ca-memb*/diff 0 0.101 0.001 "" white black \ -1.7788 9.529 0 simundump kpool /kinetics/PKC/PKC-DAG-memb* 0 -1e-12 0.0089225 0.0089225 \ 672.72 672.72 0 0 75396 4 /kinetics/dendgeom yellow blue -1.8297 5.5078 0 simundump kreac /kinetics/PKC/PKC-DAG-memb*/diff 0 0.101 0.001 "" white black \ -0.8297 8.5078 0 simundump kpool /kinetics/PKC/PKC-Ca-DAG 0 -1e-12 0.00089226 0.00089226 \ 67.273 67.273 0 0 75396 4 /kinetics/dendgeom white blue 0.2306 1.8026 0 simundump kreac /kinetics/PKC/PKC-Ca-DAG/diff 0 0.101 0.001 "" white black \ 1.2306 4.8026 0 simundump kreac /kinetics/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" white blue -3.0103 \ -1.9902 0 simundump kpool /kinetics/PKC/PKC-DAG 0 -1e-12 0.060193 0.060193 4538.3 \ 4538.3 0 0 75396 4 /kinetics/dendgeom white blue -0.99631 -1.0857 0 simundump kreac /kinetics/PKC/PKC-DAG/diff 0 0.101 0.001 "" white black \ 0.00369 1.9143 0 simundump kpool /kinetics/PKC/PKC-cytosolic 0 -1e-12 0.8223 0.8223 61998 \ 61998 0 0 75396 4 /kinetics/dendgeom white blue -6.1315 0.59711 0 simundump kreac /kinetics/PKC/PKC-cytosolic/diff 0 0.101 0.001 "" white black \ -5.1315 3.5971 0 simundump kpool /kinetics/PKC/PKM-zeta 0 -1e-12 0.01007 0.01007 759.21 759.21 \ 0 0 75396 4 /kinetics/dendgeom cyan blue -3 11 0 simundump kreac /kinetics/PKC/PKM-zeta/diff 0 0.101 0.001 "" white black -2 \ 14 0 simundump kpool /kinetics/DAG 1 -1e-12 12.2 12.2 9.1983e+05 9.1983e+05 0 0 \ 75396 4 /kinetics/dendgeom green black 4 -3 0 simundump kpool /kinetics/PKC-active 1 -1e-12 0.047627 0.047626 3590.8 3590.9 \ 0 0 75396 4 /kinetics/dendgeom red black 0 9 0 simundump kenz /kinetics/PKC-active/PKC-act-raf 1 0.0011493 0.0011493 86.652 \ 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow "" 6 10 0 simundump kenz /kinetics/PKC-active/PKC-inact-GAP 1 53.939 53.939 6.778 6.778 \ 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 4 13 0 simundump kenz /kinetics/PKC-active/PKC-act-GEF 1 726.99 726.99 91.354 91.354 \ 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 9 20 0 simundump kpool /kinetics/MAPK* 1 -1e-12 7.8539e-05 7.8539e-05 5.9215 5.9215 \ 0 0 75396 4 /kinetics/dendgeom orange yellow 13 1 0 simundump kenz /kinetics/MAPK*/MAPK*-feedback 1 3.6779e-08 3.6779e-08 \ 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 10 10 0 simundump kreac /kinetics/MAPK*/diff 0 0.101 0.001 "" white black 14 4 0 simundump group /kinetics/MAPK 0 brown black x 0 0 "" defaultfile \ defaultfile.g 0 0 0 15 11 0 simundump kpool /kinetics/MAPK/craf-1 0 0 0.48263 0.48263 36388 36388 0 0 \ 75396 4 /kinetics/dendgeom pink brown 6 8 0 simundump kreac /kinetics/MAPK/craf-1/diff 0 0.101 0.001 "" white black 7 11 \ 0 simundump kpool /kinetics/MAPK/craf-1* 0 0 0.012007 0.012007 905.28 905.28 0 \ 0 75396 4 /kinetics/dendgeom pink brown 9 8 0 simundump kreac /kinetics/MAPK/craf-1*/diff 0 0.101 0.001 "" white black 10 \ 11 0 simundump kpool /kinetics/MAPK/MAPKK 0 0 0.4946 0.4946 37291 37291 0 0 75396 \ 4 /kinetics/dendgeom pink brown 6 4 0 simundump kreac /kinetics/MAPK/MAPKK/diff 0 0.101 0.001 "" white black 7 7 0 simundump kpool /kinetics/MAPK/MAPK 0 -1e-12 3.5824 3.5824 2.701e+05 \ 2.701e+05 0 0 75396 4 /kinetics/dendgeom pink brown 6 1 0 simundump kreac /kinetics/MAPK/MAPK/diff 0 0.101 0.001 "" white black 7 4 0 simundump kpool /kinetics/MAPK/craf-1** 1 0 9.6059e-07 9.6059e-07 0.072425 \ 0.072425 0 0 75396 4 /kinetics/dendgeom hotpink brown 12 8 0 simundump kreac /kinetics/MAPK/craf-1**/diff 0 0.101 0.001 "" white black 13 \ 11 0 simundump kpool /kinetics/MAPK/MAPK-tyr 1 -1e-12 0.016774 0.016774 1264.7 \ 1264.7 0 0 75396 4 /kinetics/dendgeom orange brown 9 1 0 simundump kreac /kinetics/MAPK/MAPK-tyr/diff 0 0.101 0.001 "" white black 10 \ 4 0 simundump kpool /kinetics/MAPK/MAPKK* 0 0 8.2386e-06 8.2386e-06 0.62116 \ 0.62116 0 0 75396 4 /kinetics/dendgeom pink brown 13 4 0 simundump kenz /kinetics/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 0.00063751 48.066 \ 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 8 3 0 simundump kenz /kinetics/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 2.985e-06 0.22506 \ 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 13 3 0 simundump kreac /kinetics/MAPK/MAPKK*/diff 0 0.101 0.001 "" white black 14 7 \ 0 simundump kpool /kinetics/MAPK/MAPKK-ser 1 0 0.0020188 0.0020188 152.21 \ 152.21 0 0 75396 4 /kinetics/dendgeom pink brown 9 4 0 simundump kreac /kinetics/MAPK/MAPKK-ser/diff 0 0.101 0.001 "" white black 10 \ 7 0 simundump kpool /kinetics/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 75396 4 \ /kinetics/dendgeom 55 brown 5 6 0 simundump kenz /kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 0 0 0 0 75396 \ 0.00012505 1.2 0.3 0 0 "" red 55 "" 8 6 0 simundump kenz /kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 0 0 0 0 75396 \ 0.00012505 1.2 0.3 0 0 "" red 55 "" 11 6 0 simundump kreac /kinetics/MAPK/Raf-GTP-Ras/diff 0 0.101 0.001 "" white black \ 6 9 0 simundump kpool /kinetics/MAPK/Raf*-GTP-Ras 1 0 0.00082874 0.00082874 62.484 \ 62.484 0 0 75396 4 /kinetics/dendgeom red brown 5 5 0 simundump kenz /kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 1545.9 1545.9 \ 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 8 5 0 simundump kenz /kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 6.3096 6.3096 \ 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 11 5 0 simundump kreac /kinetics/MAPK/Raf*-GTP-Ras/diff 0 0.101 0.001 "" white black \ 6 8 0 simundump kpool /kinetics/MKP-1 1 -1e-12 0.019951 0.019951 1504.2 1504.2 0 0 \ 75396 4 /kinetics/dendgeom hotpink black 5 2 0 simundump kenz /kinetics/MKP-1/MKP1-tyr-deph 1 4.781e-05 4.781e-05 3.6047 \ 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 6 3 0 simundump kenz /kinetics/MKP-1/MKP1-thr-deph 1 2.2386e-07 2.2386e-07 0.016878 \ 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 11 3 0 simundump kreac /kinetics/MKP-1/diff 0 0.101 0.001 "" white black 6 5 0 simundump kreac /kinetics/Ras-act-craf 1 0.00013263 0.5 "" white black 3 9 0 simundump kpool /kinetics/PPhosphatase2A 1 -1e-12 0.9991 0.9991 75328 75328 0 \ 0 75396 4 /kinetics/dendgeom hotpink yellow 9 9 0 simundump kenz /kinetics/PPhosphatase2A/craf-deph 1 0.00076621 0.00076621 \ 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red hotpink "" 8 10 0 simundump kenz /kinetics/PPhosphatase2A/MAPKK-deph 1 5.2573e-07 5.2573e-07 \ 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red hotpink "" 11 7 0 simundump kenz /kinetics/PPhosphatase2A/MAPKK-deph-ser 1 0.00012882 \ 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red hotpink "" 8 7 0 simundump kenz /kinetics/PPhosphatase2A/craf**-deph 1 0.036779 0.036779 \ 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red hotpink "" 12 10 0 simundump kreac /kinetics/PPhosphatase2A/diff 0 0.101 0.001 "" white black 10 \ 12 0 simundump group /kinetics/Ras 1 blue black x 0 0 "" defaultfile defaultfile.g \ 0 0 0 14.513 16.351 0 simundump kreac /kinetics/Ras/dephosph-GEF 1 1 0 "" white blue 9.0702 17.881 \ 0 simundump kpool /kinetics/Ras/inact-GEF 1 -1e-12 0.084803 0.084803 6393.8 \ 6393.8 0 0 75396 4 /kinetics/dendgeom hotpink blue 12.453 18.352 0 simundump kenz /kinetics/Ras/inact-GEF/basal_GEF_activity 0 0.0040648 \ 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red hotpink "" 12 \ 17 0 simundump kreac /kinetics/Ras/inact-GEF/diff 0 0.101 0.001 "" white black \ 13.453 21.352 0 simundump kpool /kinetics/Ras/GEF* 1 -1e-12 0.0048465 0.0048465 365.41 365.41 \ 0 0 75396 4 /kinetics/dendgeom hotpink blue 6.4483 17.246 0 simundump kenz /kinetics/Ras/GEF*/GEF*-act-ras 1 0.0046465 0.0046465 350.33 \ 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" 7.0855 16.086 0 simundump kreac /kinetics/Ras/GEF*/diff 0 0.101 0.001 "" white black 7.4483 \ 20.246 0 simundump kpool /kinetics/Ras/GTP-Ras 1 0 0.0034512 0.0034512 260.21 260.21 0 \ 0 75396 4 /kinetics/dendgeom orange blue 12.564 13.084 0 simundump kreac /kinetics/Ras/GTP-Ras/diff 0 0.101 0.001 "" white black \ 13.564 16.084 0 simundump kpool /kinetics/Ras/GDP-Ras 1 0 0.48419 0.48419 36506 36506 0 0 \ 75396 4 /kinetics/dendgeom pink blue 6.1309 14.165 0 simundump kreac /kinetics/Ras/GDP-Ras/diff 0 0.101 0.001 "" white black \ 7.1309 17.165 0 simundump kreac /kinetics/Ras/Ras-intrinsic-GTPase 1 1e-04 0 "" white blue \ 9.0979 13.5 0 simundump kreac /kinetics/Ras/dephosph-GAP 1 0.1 0 "" white blue 4.0234 \ 15.524 0 simundump kpool /kinetics/Ras/GAP* 1 -1e-12 0.0035959 0.0035959 271.12 271.12 \ 0 0 75396 4 /kinetics/dendgeom red blue 1.3498 14.349 0 simundump kreac /kinetics/Ras/GAP*/diff 0 0.101 0.001 "" white black 2.3498 \ 17.349 0 simundump kpool /kinetics/Ras/GAP 1 -1e-12 0.0062918 0.0062918 474.38 474.38 \ 0 0 75396 4 /kinetics/dendgeom red blue 6.6549 12.338 0 simundump kenz /kinetics/Ras/GAP/GAP-inact-ras 1 2.1491e-05 2.1491e-05 1.6203 \ 1.6203 75396 0.00065634 40 10 0 0 "" red red "" 9.0121 12.403 0 simundump kreac /kinetics/Ras/GAP/diff 0 0.101 0.001 "" white black 7.6549 \ 15.338 0 simundump kreac /kinetics/Ras/CaM-bind-GEF 1 0.0026526 1 "" white blue 2.4861 \ 21.679 0 simundump kpool /kinetics/Ras/CaM-GEF 1 -1e-12 0.00021398 0.00021398 16.133 \ 16.133 0 0 75396 4 /kinetics/dendgeom pink blue 5.3451 19.58 0 simundump kenz /kinetics/Ras/CaM-GEF/CaM-GEF-act-ras 1 0.00020513 0.00020513 \ 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red pink "" 5.0223 18.657 0 simundump kreac /kinetics/Ras/CaM-GEF/diff 0 0.101 0.001 "" white black \ 6.3451 22.58 0 simundump group /kinetics/CaM 1 blue black x 0 0 "" defaultfile defaultfile.g \ 0 0 0 -10 21 0 simundump kpool /kinetics/CaM/CaM 1 -1e-12 18.403 18.403 1.3875e+06 \ 1.3875e+06 0 0 75396 4 /kinetics/dendgeom pink blue -13 30 0 simundump kreac /kinetics/CaM/CaM/diff 0 0.101 0.001 "" white black -12 33 0 simundump kreac /kinetics/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 10 "" white blue \ -10.4 23.26 0 simundump kpool /kinetics/CaM/CaM-Ca3 1 -1e-12 0.0033914 0.0033914 255.7 \ 255.7 0 0 75396 4 /kinetics/dendgeom hotpink blue -6.511 24.397 0 simundump kreac /kinetics/CaM/CaM-Ca3/diff 0 0.101 0.001 "" white black \ -5.511 27.397 0 simundump kpool /kinetics/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 1.2616e-05 0.95122 \ 0.95122 0 0 75396 4 /kinetics/dendgeom blue blue -2 24 0 simundump kreac /kinetics/CaM/CaM-Ca4/diff 0 0.101 0.001 "" white black -1 27 \ 0 simundump kreac /kinetics/CaM/CaM-bind-Ca 1 0.00011254 8.4853 "" white blue \ -10 30 0 simundump kpool /kinetics/CaM/CaM-Ca2 1 -1e-12 0.11776 0.11776 8878.5 8878.5 \ 0 0 75396 4 /kinetics/dendgeom pink blue -5.001 27.258 0 simundump kreac /kinetics/CaM/CaM-Ca2/diff 0 0.101 0.001 "" white black \ -4.001 30.258 0 simundump kreac /kinetics/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 10 "" white blue \ -8.842 26.225 0 simundump kreac /kinetics/CaM/CaM-Ca-bind-Ca 1 0.00011254 8.4853 "" white \ blue -4 30 0 simundump kpool /kinetics/CaM/CaM-Ca 1 -1e-12 1.472 1.472 1.1098e+05 \ 1.1098e+05 0 0 75396 4 /kinetics/dendgeom pink blue -7 31 0 simundump kreac /kinetics/CaM/CaM-Ca/diff 0 0.101 0.001 "" white black -6 34 \ 0 simundump kpool /kinetics/Ca 1 -1e-12 0.08 0.08 6031.7 6031.7 0 0 75396 4 \ /kinetics/dendgeom red black -18 23 0 simundump kreac /kinetics/Ca/diff 0 0.101 0.001 "" white black -17 26 0 simundump kreac /kinetics/Ras-act-unphosph-raf 0 0 0 "" white black 4 8 0 simundump group /kinetics/PKM 0 25 black x 0 0 "" PKM defaultfile.g 0 \ 5dc016e940e88c1cc7928f4e096ff523 0 -7 19 0 simundump kpool /kinetics/PKM/Ca_detector 0 -1e-12 0.99987 0.99987 75386 \ 75386 0 0 75396 4 /kinetics/dendgeom 7 25 -11 17 0 simundump kreac /kinetics/PKM/Ca_detector/diff 0 0.101 0.001 "" white black \ -10 20 0 simundump kpool /kinetics/PKM/PKM_synthesis 0 -1e-12 0.0010085 0.0010085 \ 76.04 76.04 0 0 75396 4 /kinetics/dendgeom 8 25 -11 9 0 simundump kenz /kinetics/PKM/PKM_synthesis/kenz 0 0.00010086 0.00010086 \ 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 "" -10 10 0 simundump kreac /kinetics/PKM/PKM_synthesis/diff 0 0.101 0.001 "" white black \ -10 12 0 simundump kpool /kinetics/PKM/AA_pool 0 -1e-12 1 1 75396 75396 0 0 75396 4 \ /kinetics/dendgeom 9 25 -7 12 0 simundump kreac /kinetics/PKM/PKM_degradation 0 0.0005 0 "" white 25 -8 7 0 simundump kpool /kinetics/PKM/degraded_PKM 0 -1e-12 0 0 0 0 0 0 75396 4 \ /kinetics/dendgeom 7 25 -12 5 0 simundump kpool /kinetics/PKM/Ca.detector_complex 0 -1e-12 0.00012615 \ 0.00012615 9.5109 9.5109 0 0 75396 4 /kinetics/dendgeom 7 25 -12 14 0 simundump kenz /kinetics/PKM/Ca.detector_complex/kenz 0 5.0428e-06 5.0428e-06 \ 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 "" -12 13 0 simundump kreac /kinetics/PKM/Ca.detector_complex/diff 0 0.101 0.001 "" white \ black -11 17 0 simundump kpool /kinetics/PKM/PKM_activator 0 -1e-12 0.19988 0.19988 15070 \ 15070 0 0 75396 4 /kinetics/dendgeom 6 25 -15 12 0 simundump kreac /kinetics/PKM/PKM_activator/diff 0 0.101 0.001 "" white black \ -14 15 0 simundump kreac /kinetics/PKM/turn_off_activator 0 0.001 0 "" white 25 -17 9 \ 0 simundump kreac /kinetics/PKM/trigger_PKM 0 0.00013263 1 "" white 25 -17 16 0 simundump kpool /kinetics/Ca_input 0 0 0.08 0.08 6031.7 6031.7 0 0 75396 4 \ /kinetics/dendgeom 61 black -18 30 0 simundump kreac /kinetics/Ca_diff 0 5 5 "" white black -18 26 0 simundump group /kinetics/chain 0 yellow black x 0 0 "" defaultfile \ defaultfile.g 0 0 0 4 0 0 simundump group /kinetics/chain/kinetics 0 yellow black x 0 0 "" defaultfile \ defaultfile.g 0 0 0 4 0 0 simundump group /kinetics/chain/kinetics/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 0.9507 8.2163 0 simundump kpool /kinetics/chain/kinetics/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black -0.0752 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 0.9248 4.5108 0 simundump kreac /kinetics/chain/kinetics/PKC/PKC-act-by-Ca 0 7.958e-06 0.5 "" \ white blue -0.0752 -0.12295 0 simundump kreac /kinetics/chain/kinetics/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 1.9388 0.69395 0 simundump kreac /kinetics/chain/kinetics/PKC/PKC-Ca-to-memb 0 1.2705 3.5026 \ "" white blue 0.2026 4.2533 0 simundump kreac /kinetics/chain/kinetics/PKC/PKC-DAG-to-memb 0 1 0.1 "" white \ blue 1.3832 2.7362 0 simundump kpool /kinetics/chain/kinetics/PKC/PKC-Ca-memb* 0 -1e-12 0.028634 \ 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue 1.2212 \ 6.529 0 simundump kreac /kinetics/chain/kinetics/PKC/PKC-Ca-memb*/diff 0 0.101 0.001 \ "" white black 2.2212 9.529 0 simundump kpool /kinetics/chain/kinetics/PKC/PKC-DAG-memb* 0 -1e-12 0.0089225 \ 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow blue 2.1703 \ 5.5078 0 simundump kreac /kinetics/chain/kinetics/PKC/PKC-DAG-memb*/diff 0 0.101 0.001 \ "" white black 3.1703 8.5078 0 simundump kpool /kinetics/chain/kinetics/PKC/PKC-Ca-DAG 0 -1e-12 0.00089226 \ 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white blue 4.2306 \ 1.8026 0 simundump kreac /kinetics/chain/kinetics/PKC/PKC-Ca-DAG/diff 0 0.101 0.001 "" \ white black 5.2306 4.8026 0 simundump kreac /kinetics/chain/kinetics/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 0.9897 -1.9902 0 simundump kpool /kinetics/chain/kinetics/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 3.0037 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics/PKC/PKC-DAG/diff 0 0.101 0.001 "" \ white black 4.0037 1.9143 0 simundump kpool /kinetics/chain/kinetics/PKC/PKC-cytosolic 0 -1e-12 0.8223 \ 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue -2.1315 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics/PKC/PKC-cytosolic/diff 0 0.101 0.001 \ "" white black -1.1315 3.5971 0 simundump kpool /kinetics/chain/kinetics/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 1 11 0 simundump kreac /kinetics/chain/kinetics/PKC/PKM-zeta/diff 0 0.101 0.001 "" \ white black 2 14 0 simundump kpool /kinetics/chain/kinetics/DAG 1 -1e-12 12.2 12.2 9.1983e+05 \ 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 8 -3 0 simundump kpool /kinetics/chain/kinetics/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 4 9 0 simundump kenz /kinetics/chain/kinetics/PKC-active/PKC-act-raf 1 0.0011493 \ 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow "" 10 10 0 simundump kenz /kinetics/chain/kinetics/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 8 13 0 simundump kenz /kinetics/chain/kinetics/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 13 20 0 simundump kpool /kinetics/chain/kinetics/MAPK* 1 -1e-12 7.8539e-05 7.8539e-05 \ 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 17 1 0 simundump kenz /kinetics/chain/kinetics/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 14 \ 10 0 simundump kreac /kinetics/chain/kinetics/MAPK*/diff 0 0.101 0.001 "" white \ black 18 4 0 simundump group /kinetics/chain/kinetics/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 19 11 0 simundump kpool /kinetics/chain/kinetics/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 10 8 0 simundump kreac /kinetics/chain/kinetics/MAPK/craf-1/diff 0 0.101 0.001 "" \ white black 11 11 0 simundump kpool /kinetics/chain/kinetics/MAPK/craf-1* 0 0 0.012007 0.012007 \ 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 13 8 0 simundump kreac /kinetics/chain/kinetics/MAPK/craf-1*/diff 0 0.101 0.001 "" \ white black 14 11 0 simundump kpool /kinetics/chain/kinetics/MAPK/MAPKK 0 0 0.4946 0.4946 37291 \ 37291 0 0 75396 0 /kinetics/dendgeom pink brown 10 4 0 simundump kreac /kinetics/chain/kinetics/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 11 7 0 simundump kpool /kinetics/chain/kinetics/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 10 1 0 simundump kreac /kinetics/chain/kinetics/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 11 4 0 simundump kpool /kinetics/chain/kinetics/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 16 8 0 simundump kreac /kinetics/chain/kinetics/MAPK/craf-1**/diff 0 0.101 0.001 "" \ white black 17 11 0 simundump kpool /kinetics/chain/kinetics/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 13 1 0 simundump kreac /kinetics/chain/kinetics/MAPK/MAPK-tyr/diff 0 0.101 0.001 "" \ white black 14 4 0 simundump kpool /kinetics/chain/kinetics/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 17 4 0 simundump kenz /kinetics/chain/kinetics/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 12 3 0 simundump kenz /kinetics/chain/kinetics/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 17 3 \ 0 simundump kreac /kinetics/chain/kinetics/MAPK/MAPKK*/diff 0 0.101 0.001 "" \ white black 18 7 0 simundump kpool /kinetics/chain/kinetics/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 13 4 0 simundump kreac /kinetics/chain/kinetics/MAPK/MAPKK-ser/diff 0 0.101 0.001 "" \ white black 14 7 0 simundump kpool /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 9 6 0 simundump kenz /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 0 0 \ 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 12 6 0 simundump kenz /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 0 0 \ 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 15 6 0 simundump kreac /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/diff 0 0.101 0.001 \ "" white black 10 9 0 simundump kpool /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 9 5 0 simundump kenz /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 12 \ 5 0 simundump kenz /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 15 5 0 simundump kreac /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/diff 0 0.101 0.001 \ "" white black 10 8 0 simundump kpool /kinetics/chain/kinetics/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 9 2 0 simundump kenz /kinetics/chain/kinetics/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 10 3 0 simundump kenz /kinetics/chain/kinetics/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 15 \ 3 0 simundump kreac /kinetics/chain/kinetics/MKP-1/diff 0 0.101 0.001 "" white \ black 10 5 0 simundump kreac /kinetics/chain/kinetics/Ras-act-craf 1 0.00013263 0.5 "" \ white black 7 9 0 simundump kpool /kinetics/chain/kinetics/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 13 9 0 simundump kenz /kinetics/chain/kinetics/PPhosphatase2A/craf-deph 1 0.00076621 \ 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red hotpink "" 12 10 \ 0 simundump kenz /kinetics/chain/kinetics/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 15 7 0 simundump kenz /kinetics/chain/kinetics/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 12 7 0 simundump kenz /kinetics/chain/kinetics/PPhosphatase2A/craf**-deph 1 0.036779 \ 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red hotpink "" \ 16 10 0 simundump kreac /kinetics/chain/kinetics/PPhosphatase2A/diff 0 0.101 0.001 "" \ white black 14 12 0 simundump group /kinetics/chain/kinetics/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 18.513 16.351 0 simundump kreac /kinetics/chain/kinetics/Ras/dephosph-GEF 1 1 0 "" white blue \ 13.07 17.881 0 simundump kpool /kinetics/chain/kinetics/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 16.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 16 17 0 simundump kreac /kinetics/chain/kinetics/Ras/inact-GEF/diff 0 0.101 0.001 "" \ white black 17.453 21.352 0 simundump kpool /kinetics/chain/kinetics/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 10.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 11.085 16.086 0 simundump kreac /kinetics/chain/kinetics/Ras/GEF*/diff 0 0.101 0.001 "" white \ black 11.448 20.246 0 simundump kpool /kinetics/chain/kinetics/Ras/GTP-Ras 1 0 0.0034512 0.0034512 \ 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 16.564 13.084 0 simundump kreac /kinetics/chain/kinetics/Ras/GTP-Ras/diff 0 0.101 0.001 "" \ white black 17.564 16.084 0 simundump kpool /kinetics/chain/kinetics/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 10.131 14.165 0 simundump kreac /kinetics/chain/kinetics/Ras/GDP-Ras/diff 0 0.101 0.001 "" \ white black 11.131 17.165 0 simundump kreac /kinetics/chain/kinetics/Ras/Ras-intrinsic-GTPase 1 1e-04 0 \ "" white blue 13.098 13.5 0 simundump kreac /kinetics/chain/kinetics/Ras/dephosph-GAP 1 0.1 0 "" white \ blue 8.0234 15.524 0 simundump kpool /kinetics/chain/kinetics/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 5.3498 \ 14.349 0 simundump kreac /kinetics/chain/kinetics/Ras/GAP*/diff 0 0.101 0.001 "" white \ black 6.3498 17.349 0 simundump kpool /kinetics/chain/kinetics/Ras/GAP 1 -1e-12 0.0062918 0.0062918 \ 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 10.655 12.338 0 simundump kenz /kinetics/chain/kinetics/Ras/GAP/GAP-inact-ras 1 2.1491e-05 \ 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red "" 13.012 \ 12.403 0 simundump kreac /kinetics/chain/kinetics/Ras/GAP/diff 0 0.101 0.001 "" white \ black 11.655 15.338 0 simundump kreac /kinetics/chain/kinetics/Ras/CaM-bind-GEF 1 0.0026526 1 "" \ white blue 6.4861 21.679 0 simundump kpool /kinetics/chain/kinetics/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 9.3451 \ 19.58 0 simundump kenz /kinetics/chain/kinetics/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 9.0223 18.657 0 simundump kreac /kinetics/chain/kinetics/Ras/CaM-GEF/diff 0 0.101 0.001 "" \ white black 10.345 22.58 0 simundump group /kinetics/chain/kinetics/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 -6 21 0 simundump kpool /kinetics/chain/kinetics/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue -9 30 0 simundump kreac /kinetics/chain/kinetics/CaM/CaM/diff 0 0.101 0.001 "" white \ black -8 33 0 simundump kreac /kinetics/chain/kinetics/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 10 \ "" white blue -6.4 23.26 0 simundump kpool /kinetics/chain/kinetics/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue -2.511 \ 24.397 0 simundump kreac /kinetics/chain/kinetics/CaM/CaM-Ca3/diff 0 0.101 0.001 "" \ white black -1.511 27.397 0 simundump kpool /kinetics/chain/kinetics/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 2 24 0 simundump kreac /kinetics/chain/kinetics/CaM/CaM-Ca4/diff 0 0.101 0.001 "" \ white black 3 27 0 simundump kreac /kinetics/chain/kinetics/CaM/CaM-bind-Ca 1 0.00011254 8.4853 \ "" white blue -6 30 0 simundump kpool /kinetics/chain/kinetics/CaM/CaM-Ca2 1 -1e-12 0.11776 0.11776 \ 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue -1.001 27.258 0 simundump kreac /kinetics/chain/kinetics/CaM/CaM-Ca2/diff 0 0.101 0.001 "" \ white black -0.00099993 30.258 0 simundump kreac /kinetics/chain/kinetics/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 10 \ "" white blue -4.842 26.225 0 simundump kreac /kinetics/chain/kinetics/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 0 30 0 simundump kpool /kinetics/chain/kinetics/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue -3 31 0 simundump kreac /kinetics/chain/kinetics/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black -2 34 0 simundump kpool /kinetics/chain/kinetics/Ca 1 -1e-12 0.08 0.08 6031.7 6031.7 \ 0 0 75396 0 /kinetics/dendgeom red black -14 23 0 simundump kreac /kinetics/chain/kinetics/Ca/diff 0 0.101 0.001 "" white black \ -13 26 0 simundump kreac /kinetics/chain/kinetics/Ras-act-unphosph-raf 0 0 0 "" white \ black 8 8 0 simundump group /kinetics/chain/kinetics/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 -3 19 0 simundump kpool /kinetics/chain/kinetics/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 -7 17 0 simundump kreac /kinetics/chain/kinetics/PKM/Ca_detector/diff 0 0.101 0.001 \ "" white black -6 20 0 simundump kpool /kinetics/chain/kinetics/PKM/PKM_synthesis 0 -1e-12 0.0010085 \ 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 -7 9 0 simundump kenz /kinetics/chain/kinetics/PKM/PKM_synthesis/kenz 0 0.00010086 \ 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 "" -6 10 0 simundump kreac /kinetics/chain/kinetics/PKM/PKM_synthesis/diff 0 0.101 0.001 \ "" white black -6 12 0 simundump kpool /kinetics/chain/kinetics/PKM/AA_pool 0 -1e-12 1 1 75396 75396 \ 0 0 75396 4 /kinetics/dendgeom 9 25 -3 12 0 simundump kreac /kinetics/chain/kinetics/PKM/PKM_degradation 0 0.0005 0 "" \ white 25 -4 7 0 simundump kpool /kinetics/chain/kinetics/PKM/degraded_PKM 0 -1e-12 0 0 0 0 0 \ 0 75396 4 /kinetics/dendgeom 7 25 -8 5 0 simundump kpool /kinetics/chain/kinetics/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 -8 \ 14 0 simundump kenz /kinetics/chain/kinetics/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" -8 13 0 simundump kreac /kinetics/chain/kinetics/PKM/Ca.detector_complex/diff 0 0.101 \ 0.001 "" white black -7 17 0 simundump kpool /kinetics/chain/kinetics/PKM/PKM_activator 0 -1e-12 0.19988 \ 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 -11 12 0 simundump kreac /kinetics/chain/kinetics/PKM/PKM_activator/diff 0 0.101 0.001 \ "" white black -10 15 0 simundump kreac /kinetics/chain/kinetics/PKM/turn_off_activator 0 0.001 0 "" \ white 25 -13 9 0 simundump kreac /kinetics/chain/kinetics/PKM/trigger_PKM 0 0.00013263 1 "" \ white 25 -13 16 0 simundump kpool /kinetics/chain/kinetics/Ca_input 0 0 0.08 0.08 6031.7 6031.7 \ 0 0 75396 4 /kinetics/dendgeom 61 black -14 30 0 simundump kreac /kinetics/chain/kinetics/Ca_diff 0 5 5 "" white black -14 26 \ 0 simundump group /kinetics/chain/kinetics[1] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 8 0 0 simundump group /kinetics/chain/kinetics[1]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 4.9507 8.2163 0 simundump kpool /kinetics/chain/kinetics[1]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 3.9248 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[1]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 4.9248 4.5108 0 simundump kreac /kinetics/chain/kinetics[1]/PKC/PKC-act-by-Ca 0 7.958e-06 0.5 \ "" white blue 3.9248 -0.12295 0 simundump kreac /kinetics/chain/kinetics[1]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 5.9388 0.69395 0 simundump kreac /kinetics/chain/kinetics[1]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 4.2026 4.2533 0 simundump kreac /kinetics/chain/kinetics[1]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 5.3832 2.7362 0 simundump kpool /kinetics/chain/kinetics[1]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 5.2212 6.529 0 simundump kreac /kinetics/chain/kinetics[1]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 6.2212 9.529 0 simundump kpool /kinetics/chain/kinetics[1]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 6.1703 5.5078 0 simundump kreac /kinetics/chain/kinetics[1]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 7.1703 8.5078 0 simundump kpool /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 8.2306 1.8026 0 simundump kreac /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG/diff 0 0.101 0.001 \ "" white black 9.2306 4.8026 0 simundump kreac /kinetics/chain/kinetics[1]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 4.9897 -1.9902 0 simundump kpool /kinetics/chain/kinetics[1]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 7.0037 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[1]/PKC/PKC-DAG/diff 0 0.101 0.001 "" \ white black 8.0037 1.9143 0 simundump kpool /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic 0 -1e-12 0.8223 \ 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 1.8685 0.59711 \ 0 simundump kreac /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 2.8685 3.5971 0 simundump kpool /kinetics/chain/kinetics[1]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 5 11 0 simundump kreac /kinetics/chain/kinetics[1]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 6 14 0 simundump kpool /kinetics/chain/kinetics[1]/DAG 1 -1e-12 12.2 12.2 9.1983e+05 \ 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 12 -3 0 simundump kpool /kinetics/chain/kinetics[1]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 8 9 0 simundump kenz /kinetics/chain/kinetics[1]/PKC-active/PKC-act-raf 1 0.0011493 \ 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow "" 14 10 0 simundump kenz /kinetics/chain/kinetics[1]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 12 13 0 simundump kenz /kinetics/chain/kinetics[1]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 17 20 0 simundump kpool /kinetics/chain/kinetics[1]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 21 1 \ 0 simundump kenz /kinetics/chain/kinetics[1]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 18 \ 10 0 simundump kreac /kinetics/chain/kinetics[1]/MAPK*/diff 0 0.101 0.001 "" white \ black 22 4 0 simundump group /kinetics/chain/kinetics[1]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 23 11 0 simundump kpool /kinetics/chain/kinetics[1]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 14 8 0 simundump kreac /kinetics/chain/kinetics[1]/MAPK/craf-1/diff 0 0.101 0.001 "" \ white black 15 11 0 simundump kpool /kinetics/chain/kinetics[1]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 17 8 0 simundump kreac /kinetics/chain/kinetics[1]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 18 11 0 simundump kpool /kinetics/chain/kinetics[1]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 14 4 0 simundump kreac /kinetics/chain/kinetics[1]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 15 7 0 simundump kpool /kinetics/chain/kinetics[1]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 14 1 0 simundump kreac /kinetics/chain/kinetics[1]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 15 4 0 simundump kpool /kinetics/chain/kinetics[1]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 20 8 0 simundump kreac /kinetics/chain/kinetics[1]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 21 11 0 simundump kpool /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 17 1 0 simundump kreac /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 18 4 0 simundump kpool /kinetics/chain/kinetics[1]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 21 4 0 simundump kenz /kinetics/chain/kinetics[1]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 16 3 0 simundump kenz /kinetics/chain/kinetics[1]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 21 3 \ 0 simundump kreac /kinetics/chain/kinetics[1]/MAPK/MAPKK*/diff 0 0.101 0.001 "" \ white black 22 7 0 simundump kpool /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 17 4 0 simundump kreac /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser/diff 0 0.101 0.001 \ "" white black 18 7 0 simundump kpool /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 13 6 0 simundump kenz /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 16 6 0 simundump kenz /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 19 6 0 simundump kreac /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 14 9 0 simundump kpool /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 13 5 0 simundump kenz /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 16 \ 5 0 simundump kenz /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 19 5 0 simundump kreac /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 14 8 0 simundump kpool /kinetics/chain/kinetics[1]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 13 2 0 simundump kenz /kinetics/chain/kinetics[1]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 14 3 0 simundump kenz /kinetics/chain/kinetics[1]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 19 \ 3 0 simundump kreac /kinetics/chain/kinetics[1]/MKP-1/diff 0 0.101 0.001 "" white \ black 14 5 0 simundump kreac /kinetics/chain/kinetics[1]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 11 9 0 simundump kpool /kinetics/chain/kinetics[1]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 17 9 0 simundump kenz /kinetics/chain/kinetics[1]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 16 10 0 simundump kenz /kinetics/chain/kinetics[1]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 19 7 0 simundump kenz /kinetics/chain/kinetics[1]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 16 7 0 simundump kenz /kinetics/chain/kinetics[1]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 20 10 0 simundump kreac /kinetics/chain/kinetics[1]/PPhosphatase2A/diff 0 0.101 0.001 \ "" white black 18 12 0 simundump group /kinetics/chain/kinetics[1]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 22.513 16.351 0 simundump kreac /kinetics/chain/kinetics[1]/Ras/dephosph-GEF 1 1 0 "" white \ blue 17.07 17.881 0 simundump kpool /kinetics/chain/kinetics[1]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 20.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[1]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 20 17 0 simundump kreac /kinetics/chain/kinetics[1]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 21.453 21.352 0 simundump kpool /kinetics/chain/kinetics[1]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 14.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[1]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 15.085 16.086 0 simundump kreac /kinetics/chain/kinetics[1]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 15.448 20.246 0 simundump kpool /kinetics/chain/kinetics[1]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 20.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[1]/Ras/GTP-Ras/diff 0 0.101 0.001 "" \ white black 21.564 16.084 0 simundump kpool /kinetics/chain/kinetics[1]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 14.131 14.165 0 simundump kreac /kinetics/chain/kinetics[1]/Ras/GDP-Ras/diff 0 0.101 0.001 "" \ white black 15.131 17.165 0 simundump kreac /kinetics/chain/kinetics[1]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 17.098 13.5 0 simundump kreac /kinetics/chain/kinetics[1]/Ras/dephosph-GAP 1 0.1 0 "" white \ blue 12.023 15.524 0 simundump kpool /kinetics/chain/kinetics[1]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 9.3498 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[1]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 10.35 17.349 0 simundump kpool /kinetics/chain/kinetics[1]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 14.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[1]/Ras/GAP/GAP-inact-ras 1 2.1491e-05 \ 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red "" 17.012 \ 12.403 0 simundump kreac /kinetics/chain/kinetics[1]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 15.655 15.338 0 simundump kreac /kinetics/chain/kinetics[1]/Ras/CaM-bind-GEF 1 0.0026526 1 "" \ white blue 10.486 21.679 0 simundump kpool /kinetics/chain/kinetics[1]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 13.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[1]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 13.022 18.657 0 simundump kreac /kinetics/chain/kinetics[1]/Ras/CaM-GEF/diff 0 0.101 0.001 "" \ white black 14.345 22.58 0 simundump group /kinetics/chain/kinetics[1]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 -2 21 0 simundump kpool /kinetics/chain/kinetics[1]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue -5 30 0 simundump kreac /kinetics/chain/kinetics[1]/CaM/CaM/diff 0 0.101 0.001 "" \ white black -4 33 0 simundump kreac /kinetics/chain/kinetics[1]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue -2.4 23.26 0 simundump kpool /kinetics/chain/kinetics[1]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 1.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[1]/CaM/CaM-Ca3/diff 0 0.101 0.001 "" \ white black 2.489 27.397 0 simundump kpool /kinetics/chain/kinetics[1]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 6 24 0 simundump kreac /kinetics/chain/kinetics[1]/CaM/CaM-Ca4/diff 0 0.101 0.001 "" \ white black 7 27 0 simundump kreac /kinetics/chain/kinetics[1]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue -2 30 0 simundump kpool /kinetics/chain/kinetics[1]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 2.999 27.258 \ 0 simundump kreac /kinetics/chain/kinetics[1]/CaM/CaM-Ca2/diff 0 0.101 0.001 "" \ white black 3.999 30.258 0 simundump kreac /kinetics/chain/kinetics[1]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue -0.842 26.225 0 simundump kreac /kinetics/chain/kinetics[1]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 4 30 0 simundump kpool /kinetics/chain/kinetics[1]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 1 31 0 simundump kreac /kinetics/chain/kinetics[1]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 2 34 0 simundump kpool /kinetics/chain/kinetics[1]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black -10 23 0 simundump kreac /kinetics/chain/kinetics[1]/Ca/diff 0 0.101 0.001 "" white \ black -9 26 0 simundump kreac /kinetics/chain/kinetics[1]/Ras-act-unphosph-raf 0 0 0 "" \ white black 12 8 0 simundump group /kinetics/chain/kinetics[1]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 1 19 0 simundump kpool /kinetics/chain/kinetics[1]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 -3 17 0 simundump kreac /kinetics/chain/kinetics[1]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black -2 20 0 simundump kpool /kinetics/chain/kinetics[1]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 -3 9 0 simundump kenz /kinetics/chain/kinetics[1]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" -2 10 0 simundump kreac /kinetics/chain/kinetics[1]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black -2 12 0 simundump kpool /kinetics/chain/kinetics[1]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 1 12 0 simundump kreac /kinetics/chain/kinetics[1]/PKM/PKM_degradation 0 0.0005 0 "" \ white 25 0 7 0 simundump kpool /kinetics/chain/kinetics[1]/PKM/degraded_PKM 0 -1e-12 0 0 0 0 \ 0 0 75396 4 /kinetics/dendgeom 7 25 -4 5 0 simundump kpool /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 -4 \ 14 0 simundump kenz /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" -4 13 0 simundump kreac /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black -3 17 0 simundump kpool /kinetics/chain/kinetics[1]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 -7 12 0 simundump kreac /kinetics/chain/kinetics[1]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black -6 15 0 simundump kreac /kinetics/chain/kinetics[1]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 -9 9 0 simundump kreac /kinetics/chain/kinetics[1]/PKM/trigger_PKM 0 0.00013263 1 "" \ white 25 -9 16 0 simundump kpool /kinetics/chain/kinetics[1]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black -10 30 0 simundump kreac /kinetics/chain/kinetics[1]/Ca_diff 0 5 5 "" white black -10 \ 26 0 simundump group /kinetics/chain/kinetics[2] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 12 0 0 simundump group /kinetics/chain/kinetics[2]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 8.9507 8.2163 0 simundump kpool /kinetics/chain/kinetics[2]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 7.9248 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[2]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 8.9248 4.5108 0 simundump kreac /kinetics/chain/kinetics[2]/PKC/PKC-act-by-Ca 0 7.958e-06 0.5 \ "" white blue 7.9248 -0.12295 0 simundump kreac /kinetics/chain/kinetics[2]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 9.9388 0.69395 0 simundump kreac /kinetics/chain/kinetics[2]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 8.2026 4.2533 0 simundump kreac /kinetics/chain/kinetics[2]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 9.3832 2.7362 0 simundump kpool /kinetics/chain/kinetics[2]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 9.2212 6.529 0 simundump kreac /kinetics/chain/kinetics[2]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 10.221 9.529 0 simundump kpool /kinetics/chain/kinetics[2]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 10.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[2]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 11.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 12.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG/diff 0 0.101 0.001 \ "" white black 13.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[2]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 8.9897 -1.9902 0 simundump kpool /kinetics/chain/kinetics[2]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 11.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[2]/PKC/PKC-DAG/diff 0 0.101 0.001 "" \ white black 12.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic 0 -1e-12 0.8223 \ 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 5.8685 0.59711 \ 0 simundump kreac /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 6.8685 3.5971 0 simundump kpool /kinetics/chain/kinetics[2]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 9 11 0 simundump kreac /kinetics/chain/kinetics[2]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 10 14 0 simundump kpool /kinetics/chain/kinetics[2]/DAG 1 -1e-12 12.2 12.2 9.1983e+05 \ 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 16 -3 0 simundump kpool /kinetics/chain/kinetics[2]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 12 9 0 simundump kenz /kinetics/chain/kinetics[2]/PKC-active/PKC-act-raf 1 0.0011493 \ 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow "" 18 10 0 simundump kenz /kinetics/chain/kinetics[2]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 16 13 0 simundump kenz /kinetics/chain/kinetics[2]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 21 20 0 simundump kpool /kinetics/chain/kinetics[2]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 25 1 \ 0 simundump kenz /kinetics/chain/kinetics[2]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 22 \ 10 0 simundump kreac /kinetics/chain/kinetics[2]/MAPK*/diff 0 0.101 0.001 "" white \ black 26 4 0 simundump group /kinetics/chain/kinetics[2]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 27 11 0 simundump kpool /kinetics/chain/kinetics[2]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 18 8 0 simundump kreac /kinetics/chain/kinetics[2]/MAPK/craf-1/diff 0 0.101 0.001 "" \ white black 19 11 0 simundump kpool /kinetics/chain/kinetics[2]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 21 8 0 simundump kreac /kinetics/chain/kinetics[2]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 22 11 0 simundump kpool /kinetics/chain/kinetics[2]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 18 4 0 simundump kreac /kinetics/chain/kinetics[2]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 19 7 0 simundump kpool /kinetics/chain/kinetics[2]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 18 1 0 simundump kreac /kinetics/chain/kinetics[2]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 19 4 0 simundump kpool /kinetics/chain/kinetics[2]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 24 8 0 simundump kreac /kinetics/chain/kinetics[2]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 25 11 0 simundump kpool /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 21 1 0 simundump kreac /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 22 4 0 simundump kpool /kinetics/chain/kinetics[2]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 25 4 0 simundump kenz /kinetics/chain/kinetics[2]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 20 3 0 simundump kenz /kinetics/chain/kinetics[2]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 25 3 \ 0 simundump kreac /kinetics/chain/kinetics[2]/MAPK/MAPKK*/diff 0 0.101 0.001 "" \ white black 26 7 0 simundump kpool /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 21 4 0 simundump kreac /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser/diff 0 0.101 0.001 \ "" white black 22 7 0 simundump kpool /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 17 6 0 simundump kenz /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 20 6 0 simundump kenz /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 23 6 0 simundump kreac /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 18 9 0 simundump kpool /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 17 5 0 simundump kenz /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 20 \ 5 0 simundump kenz /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 23 5 0 simundump kreac /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 18 8 0 simundump kpool /kinetics/chain/kinetics[2]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 17 2 0 simundump kenz /kinetics/chain/kinetics[2]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 18 3 0 simundump kenz /kinetics/chain/kinetics[2]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 23 \ 3 0 simundump kreac /kinetics/chain/kinetics[2]/MKP-1/diff 0 0.101 0.001 "" white \ black 18 5 0 simundump kreac /kinetics/chain/kinetics[2]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 15 9 0 simundump kpool /kinetics/chain/kinetics[2]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 21 9 0 simundump kenz /kinetics/chain/kinetics[2]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 20 10 0 simundump kenz /kinetics/chain/kinetics[2]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 23 7 0 simundump kenz /kinetics/chain/kinetics[2]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 20 7 0 simundump kenz /kinetics/chain/kinetics[2]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 24 10 0 simundump kreac /kinetics/chain/kinetics[2]/PPhosphatase2A/diff 0 0.101 0.001 \ "" white black 22 12 0 simundump group /kinetics/chain/kinetics[2]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 26.513 16.351 0 simundump kreac /kinetics/chain/kinetics[2]/Ras/dephosph-GEF 1 1 0 "" white \ blue 21.07 17.881 0 simundump kpool /kinetics/chain/kinetics[2]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 24.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[2]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 24 17 0 simundump kreac /kinetics/chain/kinetics[2]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 25.453 21.352 0 simundump kpool /kinetics/chain/kinetics[2]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 18.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[2]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 19.085 16.086 0 simundump kreac /kinetics/chain/kinetics[2]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 19.448 20.246 0 simundump kpool /kinetics/chain/kinetics[2]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 24.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[2]/Ras/GTP-Ras/diff 0 0.101 0.001 "" \ white black 25.564 16.084 0 simundump kpool /kinetics/chain/kinetics[2]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 18.131 14.165 0 simundump kreac /kinetics/chain/kinetics[2]/Ras/GDP-Ras/diff 0 0.101 0.001 "" \ white black 19.131 17.165 0 simundump kreac /kinetics/chain/kinetics[2]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 21.098 13.5 0 simundump kreac /kinetics/chain/kinetics[2]/Ras/dephosph-GAP 1 0.1 0 "" white \ blue 16.023 15.524 0 simundump kpool /kinetics/chain/kinetics[2]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 13.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[2]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 14.35 17.349 0 simundump kpool /kinetics/chain/kinetics[2]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 18.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[2]/Ras/GAP/GAP-inact-ras 1 2.1491e-05 \ 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red "" 21.012 \ 12.403 0 simundump kreac /kinetics/chain/kinetics[2]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 19.655 15.338 0 simundump kreac /kinetics/chain/kinetics[2]/Ras/CaM-bind-GEF 1 0.0026526 1 "" \ white blue 14.486 21.679 0 simundump kpool /kinetics/chain/kinetics[2]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 17.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[2]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 17.022 18.657 0 simundump kreac /kinetics/chain/kinetics[2]/Ras/CaM-GEF/diff 0 0.101 0.001 "" \ white black 18.345 22.58 0 simundump group /kinetics/chain/kinetics[2]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 2 21 0 simundump kpool /kinetics/chain/kinetics[2]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue -1 30 0 simundump kreac /kinetics/chain/kinetics[2]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 0 33 0 simundump kreac /kinetics/chain/kinetics[2]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 1.6 23.26 0 simundump kpool /kinetics/chain/kinetics[2]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 5.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[2]/CaM/CaM-Ca3/diff 0 0.101 0.001 "" \ white black 6.489 27.397 0 simundump kpool /kinetics/chain/kinetics[2]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 10 24 0 simundump kreac /kinetics/chain/kinetics[2]/CaM/CaM-Ca4/diff 0 0.101 0.001 "" \ white black 11 27 0 simundump kreac /kinetics/chain/kinetics[2]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 2 30 0 simundump kpool /kinetics/chain/kinetics[2]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 6.999 27.258 \ 0 simundump kreac /kinetics/chain/kinetics[2]/CaM/CaM-Ca2/diff 0 0.101 0.001 "" \ white black 7.999 30.258 0 simundump kreac /kinetics/chain/kinetics[2]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 3.158 26.225 0 simundump kreac /kinetics/chain/kinetics[2]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 8 30 0 simundump kpool /kinetics/chain/kinetics[2]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 5 31 0 simundump kreac /kinetics/chain/kinetics[2]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 6 34 0 simundump kpool /kinetics/chain/kinetics[2]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black -6 23 0 simundump kreac /kinetics/chain/kinetics[2]/Ca/diff 0 0.101 0.001 "" white \ black -5 26 0 simundump kreac /kinetics/chain/kinetics[2]/Ras-act-unphosph-raf 0 0 0 "" \ white black 16 8 0 simundump group /kinetics/chain/kinetics[2]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 5 19 0 simundump kpool /kinetics/chain/kinetics[2]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 1 17 0 simundump kreac /kinetics/chain/kinetics[2]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 2 20 0 simundump kpool /kinetics/chain/kinetics[2]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 1 9 0 simundump kenz /kinetics/chain/kinetics[2]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 2 10 0 simundump kreac /kinetics/chain/kinetics[2]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 2 12 0 simundump kpool /kinetics/chain/kinetics[2]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 5 12 0 simundump kreac /kinetics/chain/kinetics[2]/PKM/PKM_degradation 0 0.0005 0 "" \ white 25 4 7 0 simundump kpool /kinetics/chain/kinetics[2]/PKM/degraded_PKM 0 -1e-12 0 0 0 0 \ 0 0 75396 4 /kinetics/dendgeom 7 25 0 5 0 simundump kpool /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 0 \ 14 0 simundump kenz /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 0 13 0 simundump kreac /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 1 17 0 simundump kpool /kinetics/chain/kinetics[2]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 -3 12 0 simundump kreac /kinetics/chain/kinetics[2]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black -2 15 0 simundump kreac /kinetics/chain/kinetics[2]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 -5 9 0 simundump kreac /kinetics/chain/kinetics[2]/PKM/trigger_PKM 0 0.00013263 1 "" \ white 25 -5 16 0 simundump kpool /kinetics/chain/kinetics[2]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black -6 30 0 simundump kreac /kinetics/chain/kinetics[2]/Ca_diff 0 5 5 "" white black -6 \ 26 0 simundump group /kinetics/chain/kinetics[3] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 16 0 0 simundump group /kinetics/chain/kinetics[3]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 12.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[3]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 11.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[3]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 12.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[3]/PKC/PKC-act-by-Ca 0 7.958e-06 0.5 \ "" white blue 11.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[3]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 13.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[3]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 12.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[3]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 13.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[3]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 13.221 6.529 0 simundump kreac /kinetics/chain/kinetics[3]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 14.221 9.529 0 simundump kpool /kinetics/chain/kinetics[3]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 14.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[3]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 15.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 16.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG/diff 0 0.101 0.001 \ "" white black 17.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[3]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 12.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[3]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 15.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[3]/PKC/PKC-DAG/diff 0 0.101 0.001 "" \ white black 16.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic 0 -1e-12 0.8223 \ 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 9.8685 0.59711 \ 0 simundump kreac /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 10.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[3]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 13 11 0 simundump kreac /kinetics/chain/kinetics[3]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 14 14 0 simundump kpool /kinetics/chain/kinetics[3]/DAG 1 -1e-12 12.2 12.2 9.1983e+05 \ 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 20 -3 0 simundump kpool /kinetics/chain/kinetics[3]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 16 9 0 simundump kenz /kinetics/chain/kinetics[3]/PKC-active/PKC-act-raf 1 0.0011493 \ 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow "" 22 10 0 simundump kenz /kinetics/chain/kinetics[3]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 20 13 0 simundump kenz /kinetics/chain/kinetics[3]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 25 20 0 simundump kpool /kinetics/chain/kinetics[3]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 29 1 \ 0 simundump kenz /kinetics/chain/kinetics[3]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 26 \ 10 0 simundump kreac /kinetics/chain/kinetics[3]/MAPK*/diff 0 0.101 0.001 "" white \ black 30 4 0 simundump group /kinetics/chain/kinetics[3]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 31 11 0 simundump kpool /kinetics/chain/kinetics[3]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 22 8 0 simundump kreac /kinetics/chain/kinetics[3]/MAPK/craf-1/diff 0 0.101 0.001 "" \ white black 23 11 0 simundump kpool /kinetics/chain/kinetics[3]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 25 8 0 simundump kreac /kinetics/chain/kinetics[3]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 26 11 0 simundump kpool /kinetics/chain/kinetics[3]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 22 4 0 simundump kreac /kinetics/chain/kinetics[3]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 23 7 0 simundump kpool /kinetics/chain/kinetics[3]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 22 1 0 simundump kreac /kinetics/chain/kinetics[3]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 23 4 0 simundump kpool /kinetics/chain/kinetics[3]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 28 8 0 simundump kreac /kinetics/chain/kinetics[3]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 29 11 0 simundump kpool /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 25 1 0 simundump kreac /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 26 4 0 simundump kpool /kinetics/chain/kinetics[3]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 29 4 0 simundump kenz /kinetics/chain/kinetics[3]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 24 3 0 simundump kenz /kinetics/chain/kinetics[3]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 29 3 \ 0 simundump kreac /kinetics/chain/kinetics[3]/MAPK/MAPKK*/diff 0 0.101 0.001 "" \ white black 30 7 0 simundump kpool /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 25 4 0 simundump kreac /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser/diff 0 0.101 0.001 \ "" white black 26 7 0 simundump kpool /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 21 6 0 simundump kenz /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 24 6 0 simundump kenz /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 27 6 0 simundump kreac /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 22 9 0 simundump kpool /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 21 5 0 simundump kenz /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 24 \ 5 0 simundump kenz /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 27 5 0 simundump kreac /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 22 8 0 simundump kpool /kinetics/chain/kinetics[3]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 21 2 0 simundump kenz /kinetics/chain/kinetics[3]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 22 3 0 simundump kenz /kinetics/chain/kinetics[3]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 27 \ 3 0 simundump kreac /kinetics/chain/kinetics[3]/MKP-1/diff 0 0.101 0.001 "" white \ black 22 5 0 simundump kreac /kinetics/chain/kinetics[3]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 19 9 0 simundump kpool /kinetics/chain/kinetics[3]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 25 9 0 simundump kenz /kinetics/chain/kinetics[3]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 24 10 0 simundump kenz /kinetics/chain/kinetics[3]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 27 7 0 simundump kenz /kinetics/chain/kinetics[3]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 24 7 0 simundump kenz /kinetics/chain/kinetics[3]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 28 10 0 simundump kreac /kinetics/chain/kinetics[3]/PPhosphatase2A/diff 0 0.101 0.001 \ "" white black 26 12 0 simundump group /kinetics/chain/kinetics[3]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 30.513 16.351 0 simundump kreac /kinetics/chain/kinetics[3]/Ras/dephosph-GEF 1 1 0 "" white \ blue 25.07 17.881 0 simundump kpool /kinetics/chain/kinetics[3]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 28.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[3]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 28 17 0 simundump kreac /kinetics/chain/kinetics[3]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 29.453 21.352 0 simundump kpool /kinetics/chain/kinetics[3]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 22.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[3]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 23.085 16.086 0 simundump kreac /kinetics/chain/kinetics[3]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 23.448 20.246 0 simundump kpool /kinetics/chain/kinetics[3]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 28.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[3]/Ras/GTP-Ras/diff 0 0.101 0.001 "" \ white black 29.564 16.084 0 simundump kpool /kinetics/chain/kinetics[3]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 22.131 14.165 0 simundump kreac /kinetics/chain/kinetics[3]/Ras/GDP-Ras/diff 0 0.101 0.001 "" \ white black 23.131 17.165 0 simundump kreac /kinetics/chain/kinetics[3]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 25.098 13.5 0 simundump kreac /kinetics/chain/kinetics[3]/Ras/dephosph-GAP 1 0.1 0 "" white \ blue 20.023 15.524 0 simundump kpool /kinetics/chain/kinetics[3]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 17.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[3]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 18.35 17.349 0 simundump kpool /kinetics/chain/kinetics[3]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 22.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[3]/Ras/GAP/GAP-inact-ras 1 2.1491e-05 \ 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red "" 25.012 \ 12.403 0 simundump kreac /kinetics/chain/kinetics[3]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 23.655 15.338 0 simundump kreac /kinetics/chain/kinetics[3]/Ras/CaM-bind-GEF 1 0.0026526 1 "" \ white blue 18.486 21.679 0 simundump kpool /kinetics/chain/kinetics[3]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 21.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[3]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 21.022 18.657 0 simundump kreac /kinetics/chain/kinetics[3]/Ras/CaM-GEF/diff 0 0.101 0.001 "" \ white black 22.345 22.58 0 simundump group /kinetics/chain/kinetics[3]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 6 21 0 simundump kpool /kinetics/chain/kinetics[3]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 3 30 0 simundump kreac /kinetics/chain/kinetics[3]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 4 33 0 simundump kreac /kinetics/chain/kinetics[3]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 5.6 23.26 0 simundump kpool /kinetics/chain/kinetics[3]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 9.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[3]/CaM/CaM-Ca3/diff 0 0.101 0.001 "" \ white black 10.489 27.397 0 simundump kpool /kinetics/chain/kinetics[3]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 14 24 0 simundump kreac /kinetics/chain/kinetics[3]/CaM/CaM-Ca4/diff 0 0.101 0.001 "" \ white black 15 27 0 simundump kreac /kinetics/chain/kinetics[3]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 6 30 0 simundump kpool /kinetics/chain/kinetics[3]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 10.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[3]/CaM/CaM-Ca2/diff 0 0.101 0.001 "" \ white black 11.999 30.258 0 simundump kreac /kinetics/chain/kinetics[3]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 7.158 26.225 0 simundump kreac /kinetics/chain/kinetics[3]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 12 30 0 simundump kpool /kinetics/chain/kinetics[3]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 9 31 0 simundump kreac /kinetics/chain/kinetics[3]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 10 34 0 simundump kpool /kinetics/chain/kinetics[3]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black -2 23 0 simundump kreac /kinetics/chain/kinetics[3]/Ca/diff 0 0.101 0.001 "" white \ black -1 26 0 simundump kreac /kinetics/chain/kinetics[3]/Ras-act-unphosph-raf 0 0 0 "" \ white black 20 8 0 simundump group /kinetics/chain/kinetics[3]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 9 19 0 simundump kpool /kinetics/chain/kinetics[3]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 5 17 0 simundump kreac /kinetics/chain/kinetics[3]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 6 20 0 simundump kpool /kinetics/chain/kinetics[3]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 5 9 0 simundump kenz /kinetics/chain/kinetics[3]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 6 10 0 simundump kreac /kinetics/chain/kinetics[3]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 6 12 0 simundump kpool /kinetics/chain/kinetics[3]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 9 12 0 simundump kreac /kinetics/chain/kinetics[3]/PKM/PKM_degradation 0 0.0005 0 "" \ white 25 8 7 0 simundump kpool /kinetics/chain/kinetics[3]/PKM/degraded_PKM 0 -1e-12 0 0 0 0 \ 0 0 75396 4 /kinetics/dendgeom 7 25 4 5 0 simundump kpool /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 4 \ 14 0 simundump kenz /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 4 13 0 simundump kreac /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 5 17 0 simundump kpool /kinetics/chain/kinetics[3]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 1 12 0 simundump kreac /kinetics/chain/kinetics[3]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 2 15 0 simundump kreac /kinetics/chain/kinetics[3]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 -1 9 0 simundump kreac /kinetics/chain/kinetics[3]/PKM/trigger_PKM 0 0.00013263 1 "" \ white 25 -1 16 0 simundump kpool /kinetics/chain/kinetics[3]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black -2 30 0 simundump kreac /kinetics/chain/kinetics[3]/Ca_diff 0 5 5 "" white black -2 \ 26 0 simundump group /kinetics/chain/kinetics[4] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 20 0 0 simundump group /kinetics/chain/kinetics[4]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 16.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[4]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 15.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[4]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 16.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[4]/PKC/PKC-act-by-Ca 0 7.958e-06 0.5 \ "" white blue 15.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[4]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 17.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[4]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 16.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[4]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 17.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[4]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 17.221 6.529 0 simundump kreac /kinetics/chain/kinetics[4]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 18.221 9.529 0 simundump kpool /kinetics/chain/kinetics[4]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 18.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[4]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 19.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 20.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG/diff 0 0.101 0.001 \ "" white black 21.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[4]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 16.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[4]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 19.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[4]/PKC/PKC-DAG/diff 0 0.101 0.001 "" \ white black 20.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic 0 -1e-12 0.8223 \ 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 13.868 0.59711 \ 0 simundump kreac /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 14.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[4]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 17 11 0 simundump kreac /kinetics/chain/kinetics[4]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 18 14 0 simundump kpool /kinetics/chain/kinetics[4]/DAG 1 -1e-12 12.2 12.2 9.1983e+05 \ 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 24 -3 0 simundump kpool /kinetics/chain/kinetics[4]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 20 9 0 simundump kenz /kinetics/chain/kinetics[4]/PKC-active/PKC-act-raf 1 0.0011493 \ 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow "" 26 10 0 simundump kenz /kinetics/chain/kinetics[4]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 24 13 0 simundump kenz /kinetics/chain/kinetics[4]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 29 20 0 simundump kpool /kinetics/chain/kinetics[4]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 33 1 \ 0 simundump kenz /kinetics/chain/kinetics[4]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 30 \ 10 0 simundump kreac /kinetics/chain/kinetics[4]/MAPK*/diff 0 0.101 0.001 "" white \ black 34 4 0 simundump group /kinetics/chain/kinetics[4]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 35 11 0 simundump kpool /kinetics/chain/kinetics[4]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 26 8 0 simundump kreac /kinetics/chain/kinetics[4]/MAPK/craf-1/diff 0 0.101 0.001 "" \ white black 27 11 0 simundump kpool /kinetics/chain/kinetics[4]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 29 8 0 simundump kreac /kinetics/chain/kinetics[4]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 30 11 0 simundump kpool /kinetics/chain/kinetics[4]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 26 4 0 simundump kreac /kinetics/chain/kinetics[4]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 27 7 0 simundump kpool /kinetics/chain/kinetics[4]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 26 1 0 simundump kreac /kinetics/chain/kinetics[4]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 27 4 0 simundump kpool /kinetics/chain/kinetics[4]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 32 8 0 simundump kreac /kinetics/chain/kinetics[4]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 33 11 0 simundump kpool /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 29 1 0 simundump kreac /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 30 4 0 simundump kpool /kinetics/chain/kinetics[4]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 33 4 0 simundump kenz /kinetics/chain/kinetics[4]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 28 3 0 simundump kenz /kinetics/chain/kinetics[4]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 33 3 \ 0 simundump kreac /kinetics/chain/kinetics[4]/MAPK/MAPKK*/diff 0 0.101 0.001 "" \ white black 34 7 0 simundump kpool /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 29 4 0 simundump kreac /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser/diff 0 0.101 0.001 \ "" white black 30 7 0 simundump kpool /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 25 6 0 simundump kenz /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 28 6 0 simundump kenz /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 31 6 0 simundump kreac /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 26 9 0 simundump kpool /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 25 5 0 simundump kenz /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 28 \ 5 0 simundump kenz /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 31 5 0 simundump kreac /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 26 8 0 simundump kpool /kinetics/chain/kinetics[4]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 25 2 0 simundump kenz /kinetics/chain/kinetics[4]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 26 3 0 simundump kenz /kinetics/chain/kinetics[4]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 31 \ 3 0 simundump kreac /kinetics/chain/kinetics[4]/MKP-1/diff 0 0.101 0.001 "" white \ black 26 5 0 simundump kreac /kinetics/chain/kinetics[4]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 23 9 0 simundump kpool /kinetics/chain/kinetics[4]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 29 9 0 simundump kenz /kinetics/chain/kinetics[4]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 28 10 0 simundump kenz /kinetics/chain/kinetics[4]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 31 7 0 simundump kenz /kinetics/chain/kinetics[4]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 28 7 0 simundump kenz /kinetics/chain/kinetics[4]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 32 10 0 simundump kreac /kinetics/chain/kinetics[4]/PPhosphatase2A/diff 0 0.101 0.001 \ "" white black 30 12 0 simundump group /kinetics/chain/kinetics[4]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 34.513 16.351 0 simundump kreac /kinetics/chain/kinetics[4]/Ras/dephosph-GEF 1 1 0 "" white \ blue 29.07 17.881 0 simundump kpool /kinetics/chain/kinetics[4]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 32.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[4]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 32 17 0 simundump kreac /kinetics/chain/kinetics[4]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 33.453 21.352 0 simundump kpool /kinetics/chain/kinetics[4]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 26.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[4]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 27.085 16.086 0 simundump kreac /kinetics/chain/kinetics[4]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 27.448 20.246 0 simundump kpool /kinetics/chain/kinetics[4]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 32.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[4]/Ras/GTP-Ras/diff 0 0.101 0.001 "" \ white black 33.564 16.084 0 simundump kpool /kinetics/chain/kinetics[4]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 26.131 14.165 0 simundump kreac /kinetics/chain/kinetics[4]/Ras/GDP-Ras/diff 0 0.101 0.001 "" \ white black 27.131 17.165 0 simundump kreac /kinetics/chain/kinetics[4]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 29.098 13.5 0 simundump kreac /kinetics/chain/kinetics[4]/Ras/dephosph-GAP 1 0.1 0 "" white \ blue 24.023 15.524 0 simundump kpool /kinetics/chain/kinetics[4]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 21.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[4]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 22.35 17.349 0 simundump kpool /kinetics/chain/kinetics[4]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 26.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[4]/Ras/GAP/GAP-inact-ras 1 2.1491e-05 \ 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red "" 29.012 \ 12.403 0 simundump kreac /kinetics/chain/kinetics[4]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 27.655 15.338 0 simundump kreac /kinetics/chain/kinetics[4]/Ras/CaM-bind-GEF 1 0.0026526 1 "" \ white blue 22.486 21.679 0 simundump kpool /kinetics/chain/kinetics[4]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 25.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[4]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 25.022 18.657 0 simundump kreac /kinetics/chain/kinetics[4]/Ras/CaM-GEF/diff 0 0.101 0.001 "" \ white black 26.345 22.58 0 simundump group /kinetics/chain/kinetics[4]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 10 21 0 simundump kpool /kinetics/chain/kinetics[4]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 7 30 0 simundump kreac /kinetics/chain/kinetics[4]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 8 33 0 simundump kreac /kinetics/chain/kinetics[4]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 9.6 23.26 0 simundump kpool /kinetics/chain/kinetics[4]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 13.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[4]/CaM/CaM-Ca3/diff 0 0.101 0.001 "" \ white black 14.489 27.397 0 simundump kpool /kinetics/chain/kinetics[4]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 18 24 0 simundump kreac /kinetics/chain/kinetics[4]/CaM/CaM-Ca4/diff 0 0.101 0.001 "" \ white black 19 27 0 simundump kreac /kinetics/chain/kinetics[4]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 10 30 0 simundump kpool /kinetics/chain/kinetics[4]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 14.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[4]/CaM/CaM-Ca2/diff 0 0.101 0.001 "" \ white black 15.999 30.258 0 simundump kreac /kinetics/chain/kinetics[4]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 11.158 26.225 0 simundump kreac /kinetics/chain/kinetics[4]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 16 30 0 simundump kpool /kinetics/chain/kinetics[4]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 13 31 0 simundump kreac /kinetics/chain/kinetics[4]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 14 34 0 simundump kpool /kinetics/chain/kinetics[4]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 2 23 0 simundump kreac /kinetics/chain/kinetics[4]/Ca/diff 0 0.101 0.001 "" white \ black 3 26 0 simundump kreac /kinetics/chain/kinetics[4]/Ras-act-unphosph-raf 0 0 0 "" \ white black 24 8 0 simundump group /kinetics/chain/kinetics[4]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 13 19 0 simundump kpool /kinetics/chain/kinetics[4]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 9 17 0 simundump kreac /kinetics/chain/kinetics[4]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 10 20 0 simundump kpool /kinetics/chain/kinetics[4]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 9 9 0 simundump kenz /kinetics/chain/kinetics[4]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 10 10 0 simundump kreac /kinetics/chain/kinetics[4]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 10 12 0 simundump kpool /kinetics/chain/kinetics[4]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 13 12 0 simundump kreac /kinetics/chain/kinetics[4]/PKM/PKM_degradation 0 0.0005 0 "" \ white 25 12 7 0 simundump kpool /kinetics/chain/kinetics[4]/PKM/degraded_PKM 0 -1e-12 0 0 0 0 \ 0 0 75396 4 /kinetics/dendgeom 7 25 8 5 0 simundump kpool /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 8 \ 14 0 simundump kenz /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 8 13 0 simundump kreac /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 9 17 0 simundump kpool /kinetics/chain/kinetics[4]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 5 12 0 simundump kreac /kinetics/chain/kinetics[4]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 6 15 0 simundump kreac /kinetics/chain/kinetics[4]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 3 9 0 simundump kreac /kinetics/chain/kinetics[4]/PKM/trigger_PKM 0 0.00013263 1 "" \ white 25 3 16 0 simundump kpool /kinetics/chain/kinetics[4]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 2 30 0 simundump kreac /kinetics/chain/kinetics[4]/Ca_diff 0 5 5 "" white black 2 26 \ 0 simundump group /kinetics/chain/kinetics[5] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 24 0 0 simundump group /kinetics/chain/kinetics[5]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 20.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[5]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 19.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[5]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 20.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[5]/PKC/PKC-act-by-Ca 0 7.958e-06 0.5 \ "" white blue 19.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[5]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 21.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[5]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 20.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[5]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 21.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[5]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 21.221 6.529 0 simundump kreac /kinetics/chain/kinetics[5]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 22.221 9.529 0 simundump kpool /kinetics/chain/kinetics[5]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 22.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[5]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 23.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 24.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG/diff 0 0.101 0.001 \ "" white black 25.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[5]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 20.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[5]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 23.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[5]/PKC/PKC-DAG/diff 0 0.101 0.001 "" \ white black 24.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic 0 -1e-12 0.8223 \ 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 17.868 0.59711 \ 0 simundump kreac /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 18.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[5]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 21 11 0 simundump kreac /kinetics/chain/kinetics[5]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 22 14 0 simundump kpool /kinetics/chain/kinetics[5]/DAG 1 -1e-12 12.2 12.2 9.1983e+05 \ 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 28 -3 0 simundump kpool /kinetics/chain/kinetics[5]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 24 9 0 simundump kenz /kinetics/chain/kinetics[5]/PKC-active/PKC-act-raf 1 0.0011493 \ 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow "" 30 10 0 simundump kenz /kinetics/chain/kinetics[5]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 28 13 0 simundump kenz /kinetics/chain/kinetics[5]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 33 20 0 simundump kpool /kinetics/chain/kinetics[5]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 37 1 \ 0 simundump kenz /kinetics/chain/kinetics[5]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 34 \ 10 0 simundump kreac /kinetics/chain/kinetics[5]/MAPK*/diff 0 0.101 0.001 "" white \ black 38 4 0 simundump group /kinetics/chain/kinetics[5]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 39 11 0 simundump kpool /kinetics/chain/kinetics[5]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 30 8 0 simundump kreac /kinetics/chain/kinetics[5]/MAPK/craf-1/diff 0 0.101 0.001 "" \ white black 31 11 0 simundump kpool /kinetics/chain/kinetics[5]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 33 8 0 simundump kreac /kinetics/chain/kinetics[5]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 34 11 0 simundump kpool /kinetics/chain/kinetics[5]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 30 4 0 simundump kreac /kinetics/chain/kinetics[5]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 31 7 0 simundump kpool /kinetics/chain/kinetics[5]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 30 1 0 simundump kreac /kinetics/chain/kinetics[5]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 31 4 0 simundump kpool /kinetics/chain/kinetics[5]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 36 8 0 simundump kreac /kinetics/chain/kinetics[5]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 37 11 0 simundump kpool /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 33 1 0 simundump kreac /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 34 4 0 simundump kpool /kinetics/chain/kinetics[5]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 37 4 0 simundump kenz /kinetics/chain/kinetics[5]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 32 3 0 simundump kenz /kinetics/chain/kinetics[5]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 37 3 \ 0 simundump kreac /kinetics/chain/kinetics[5]/MAPK/MAPKK*/diff 0 0.101 0.001 "" \ white black 38 7 0 simundump kpool /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 33 4 0 simundump kreac /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser/diff 0 0.101 0.001 \ "" white black 34 7 0 simundump kpool /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 29 6 0 simundump kenz /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 32 6 0 simundump kenz /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 35 6 0 simundump kreac /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 30 9 0 simundump kpool /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 29 5 0 simundump kenz /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 32 \ 5 0 simundump kenz /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 35 5 0 simundump kreac /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 30 8 0 simundump kpool /kinetics/chain/kinetics[5]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 29 2 0 simundump kenz /kinetics/chain/kinetics[5]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 30 3 0 simundump kenz /kinetics/chain/kinetics[5]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 35 \ 3 0 simundump kreac /kinetics/chain/kinetics[5]/MKP-1/diff 0 0.101 0.001 "" white \ black 30 5 0 simundump kreac /kinetics/chain/kinetics[5]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 27 9 0 simundump kpool /kinetics/chain/kinetics[5]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 33 9 0 simundump kenz /kinetics/chain/kinetics[5]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 32 10 0 simundump kenz /kinetics/chain/kinetics[5]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 35 7 0 simundump kenz /kinetics/chain/kinetics[5]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 32 7 0 simundump kenz /kinetics/chain/kinetics[5]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 36 10 0 simundump kreac /kinetics/chain/kinetics[5]/PPhosphatase2A/diff 0 0.101 0.001 \ "" white black 34 12 0 simundump group /kinetics/chain/kinetics[5]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 38.513 16.351 0 simundump kreac /kinetics/chain/kinetics[5]/Ras/dephosph-GEF 1 1 0 "" white \ blue 33.07 17.881 0 simundump kpool /kinetics/chain/kinetics[5]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 36.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[5]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 36 17 0 simundump kreac /kinetics/chain/kinetics[5]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 37.453 21.352 0 simundump kpool /kinetics/chain/kinetics[5]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 30.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[5]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 31.085 16.086 0 simundump kreac /kinetics/chain/kinetics[5]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 31.448 20.246 0 simundump kpool /kinetics/chain/kinetics[5]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 36.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[5]/Ras/GTP-Ras/diff 0 0.101 0.001 "" \ white black 37.564 16.084 0 simundump kpool /kinetics/chain/kinetics[5]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 30.131 14.165 0 simundump kreac /kinetics/chain/kinetics[5]/Ras/GDP-Ras/diff 0 0.101 0.001 "" \ white black 31.131 17.165 0 simundump kreac /kinetics/chain/kinetics[5]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 33.098 13.5 0 simundump kreac /kinetics/chain/kinetics[5]/Ras/dephosph-GAP 1 0.1 0 "" white \ blue 28.023 15.524 0 simundump kpool /kinetics/chain/kinetics[5]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 25.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[5]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 26.35 17.349 0 simundump kpool /kinetics/chain/kinetics[5]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 30.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[5]/Ras/GAP/GAP-inact-ras 1 2.1491e-05 \ 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red "" 33.012 \ 12.403 0 simundump kreac /kinetics/chain/kinetics[5]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 31.655 15.338 0 simundump kreac /kinetics/chain/kinetics[5]/Ras/CaM-bind-GEF 1 0.0026526 1 "" \ white blue 26.486 21.679 0 simundump kpool /kinetics/chain/kinetics[5]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 29.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[5]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 29.022 18.657 0 simundump kreac /kinetics/chain/kinetics[5]/Ras/CaM-GEF/diff 0 0.101 0.001 "" \ white black 30.345 22.58 0 simundump group /kinetics/chain/kinetics[5]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 14 21 0 simundump kpool /kinetics/chain/kinetics[5]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 11 30 0 simundump kreac /kinetics/chain/kinetics[5]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 12 33 0 simundump kreac /kinetics/chain/kinetics[5]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 13.6 23.26 0 simundump kpool /kinetics/chain/kinetics[5]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 17.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[5]/CaM/CaM-Ca3/diff 0 0.101 0.001 "" \ white black 18.489 27.397 0 simundump kpool /kinetics/chain/kinetics[5]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 22 24 0 simundump kreac /kinetics/chain/kinetics[5]/CaM/CaM-Ca4/diff 0 0.101 0.001 "" \ white black 23 27 0 simundump kreac /kinetics/chain/kinetics[5]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 14 30 0 simundump kpool /kinetics/chain/kinetics[5]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 18.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[5]/CaM/CaM-Ca2/diff 0 0.101 0.001 "" \ white black 19.999 30.258 0 simundump kreac /kinetics/chain/kinetics[5]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 15.158 26.225 0 simundump kreac /kinetics/chain/kinetics[5]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 20 30 0 simundump kpool /kinetics/chain/kinetics[5]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 17 31 0 simundump kreac /kinetics/chain/kinetics[5]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 18 34 0 simundump kpool /kinetics/chain/kinetics[5]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 6 23 0 simundump kreac /kinetics/chain/kinetics[5]/Ca/diff 0 0.101 0.001 "" white \ black 7 26 0 simundump kreac /kinetics/chain/kinetics[5]/Ras-act-unphosph-raf 0 0 0 "" \ white black 28 8 0 simundump group /kinetics/chain/kinetics[5]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 17 19 0 simundump kpool /kinetics/chain/kinetics[5]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 13 17 0 simundump kreac /kinetics/chain/kinetics[5]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 14 20 0 simundump kpool /kinetics/chain/kinetics[5]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 13 9 0 simundump kenz /kinetics/chain/kinetics[5]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 14 10 0 simundump kreac /kinetics/chain/kinetics[5]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 14 12 0 simundump kpool /kinetics/chain/kinetics[5]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 17 12 0 simundump kreac /kinetics/chain/kinetics[5]/PKM/PKM_degradation 0 0.0005 0 "" \ white 25 16 7 0 simundump kpool /kinetics/chain/kinetics[5]/PKM/degraded_PKM 0 -1e-12 0 0 0 0 \ 0 0 75396 4 /kinetics/dendgeom 7 25 12 5 0 simundump kpool /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 12 \ 14 0 simundump kenz /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 12 13 0 simundump kreac /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 13 17 0 simundump kpool /kinetics/chain/kinetics[5]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 9 12 0 simundump kreac /kinetics/chain/kinetics[5]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 10 15 0 simundump kreac /kinetics/chain/kinetics[5]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 7 9 0 simundump kreac /kinetics/chain/kinetics[5]/PKM/trigger_PKM 0 0.00013263 1 "" \ white 25 7 16 0 simundump kpool /kinetics/chain/kinetics[5]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 6 30 0 simundump kreac /kinetics/chain/kinetics[5]/Ca_diff 0 5 5 "" white black 6 26 \ 0 simundump group /kinetics/chain/kinetics[6] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 28 0 0 simundump group /kinetics/chain/kinetics[6]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 24.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[6]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 23.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[6]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 24.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[6]/PKC/PKC-act-by-Ca 0 7.958e-06 0.5 \ "" white blue 23.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[6]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 25.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[6]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 24.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[6]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 25.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[6]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 25.221 6.529 0 simundump kreac /kinetics/chain/kinetics[6]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 26.221 9.529 0 simundump kpool /kinetics/chain/kinetics[6]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 26.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[6]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 27.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 28.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG/diff 0 0.101 0.001 \ "" white black 29.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[6]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 24.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[6]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 27.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[6]/PKC/PKC-DAG/diff 0 0.101 0.001 "" \ white black 28.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic 0 -1e-12 0.8223 \ 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 21.868 0.59711 \ 0 simundump kreac /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 22.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[6]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 25 11 0 simundump kreac /kinetics/chain/kinetics[6]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 26 14 0 simundump kpool /kinetics/chain/kinetics[6]/DAG 1 -1e-12 12.2 12.2 9.1983e+05 \ 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 32 -3 0 simundump kpool /kinetics/chain/kinetics[6]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 28 9 0 simundump kenz /kinetics/chain/kinetics[6]/PKC-active/PKC-act-raf 1 0.0011493 \ 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow "" 34 10 0 simundump kenz /kinetics/chain/kinetics[6]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 32 13 0 simundump kenz /kinetics/chain/kinetics[6]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 37 20 0 simundump kpool /kinetics/chain/kinetics[6]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 41 1 \ 0 simundump kenz /kinetics/chain/kinetics[6]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 38 \ 10 0 simundump kreac /kinetics/chain/kinetics[6]/MAPK*/diff 0 0.101 0.001 "" white \ black 42 4 0 simundump group /kinetics/chain/kinetics[6]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 43 11 0 simundump kpool /kinetics/chain/kinetics[6]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 34 8 0 simundump kreac /kinetics/chain/kinetics[6]/MAPK/craf-1/diff 0 0.101 0.001 "" \ white black 35 11 0 simundump kpool /kinetics/chain/kinetics[6]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 37 8 0 simundump kreac /kinetics/chain/kinetics[6]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 38 11 0 simundump kpool /kinetics/chain/kinetics[6]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 34 4 0 simundump kreac /kinetics/chain/kinetics[6]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 35 7 0 simundump kpool /kinetics/chain/kinetics[6]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 34 1 0 simundump kreac /kinetics/chain/kinetics[6]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 35 4 0 simundump kpool /kinetics/chain/kinetics[6]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 40 8 0 simundump kreac /kinetics/chain/kinetics[6]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 41 11 0 simundump kpool /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 37 1 0 simundump kreac /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 38 4 0 simundump kpool /kinetics/chain/kinetics[6]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 41 4 0 simundump kenz /kinetics/chain/kinetics[6]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 36 3 0 simundump kenz /kinetics/chain/kinetics[6]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 41 3 \ 0 simundump kreac /kinetics/chain/kinetics[6]/MAPK/MAPKK*/diff 0 0.101 0.001 "" \ white black 42 7 0 simundump kpool /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 37 4 0 simundump kreac /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser/diff 0 0.101 0.001 \ "" white black 38 7 0 simundump kpool /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 33 6 0 simundump kenz /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 36 6 0 simundump kenz /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 39 6 0 simundump kreac /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 34 9 0 simundump kpool /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 33 5 0 simundump kenz /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 36 \ 5 0 simundump kenz /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 39 5 0 simundump kreac /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 34 8 0 simundump kpool /kinetics/chain/kinetics[6]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 33 2 0 simundump kenz /kinetics/chain/kinetics[6]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 34 3 0 simundump kenz /kinetics/chain/kinetics[6]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 39 \ 3 0 simundump kreac /kinetics/chain/kinetics[6]/MKP-1/diff 0 0.101 0.001 "" white \ black 34 5 0 simundump kreac /kinetics/chain/kinetics[6]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 31 9 0 simundump kpool /kinetics/chain/kinetics[6]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 37 9 0 simundump kenz /kinetics/chain/kinetics[6]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 36 10 0 simundump kenz /kinetics/chain/kinetics[6]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 39 7 0 simundump kenz /kinetics/chain/kinetics[6]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 36 7 0 simundump kenz /kinetics/chain/kinetics[6]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 40 10 0 simundump kreac /kinetics/chain/kinetics[6]/PPhosphatase2A/diff 0 0.101 0.001 \ "" white black 38 12 0 simundump group /kinetics/chain/kinetics[6]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 42.513 16.351 0 simundump kreac /kinetics/chain/kinetics[6]/Ras/dephosph-GEF 1 1 0 "" white \ blue 37.07 17.881 0 simundump kpool /kinetics/chain/kinetics[6]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 40.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[6]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 40 17 0 simundump kreac /kinetics/chain/kinetics[6]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 41.453 21.352 0 simundump kpool /kinetics/chain/kinetics[6]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 34.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[6]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 35.085 16.086 0 simundump kreac /kinetics/chain/kinetics[6]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 35.448 20.246 0 simundump kpool /kinetics/chain/kinetics[6]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 40.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[6]/Ras/GTP-Ras/diff 0 0.101 0.001 "" \ white black 41.564 16.084 0 simundump kpool /kinetics/chain/kinetics[6]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 34.131 14.165 0 simundump kreac /kinetics/chain/kinetics[6]/Ras/GDP-Ras/diff 0 0.101 0.001 "" \ white black 35.131 17.165 0 simundump kreac /kinetics/chain/kinetics[6]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 37.098 13.5 0 simundump kreac /kinetics/chain/kinetics[6]/Ras/dephosph-GAP 1 0.1 0 "" white \ blue 32.023 15.524 0 simundump kpool /kinetics/chain/kinetics[6]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 29.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[6]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 30.35 17.349 0 simundump kpool /kinetics/chain/kinetics[6]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 34.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[6]/Ras/GAP/GAP-inact-ras 1 2.1491e-05 \ 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red "" 37.012 \ 12.403 0 simundump kreac /kinetics/chain/kinetics[6]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 35.655 15.338 0 simundump kreac /kinetics/chain/kinetics[6]/Ras/CaM-bind-GEF 1 0.0026526 1 "" \ white blue 30.486 21.679 0 simundump kpool /kinetics/chain/kinetics[6]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 33.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[6]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 33.022 18.657 0 simundump kreac /kinetics/chain/kinetics[6]/Ras/CaM-GEF/diff 0 0.101 0.001 "" \ white black 34.345 22.58 0 simundump group /kinetics/chain/kinetics[6]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 18 21 0 simundump kpool /kinetics/chain/kinetics[6]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 15 30 0 simundump kreac /kinetics/chain/kinetics[6]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 16 33 0 simundump kreac /kinetics/chain/kinetics[6]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 17.6 23.26 0 simundump kpool /kinetics/chain/kinetics[6]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 21.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[6]/CaM/CaM-Ca3/diff 0 0.101 0.001 "" \ white black 22.489 27.397 0 simundump kpool /kinetics/chain/kinetics[6]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 26 24 0 simundump kreac /kinetics/chain/kinetics[6]/CaM/CaM-Ca4/diff 0 0.101 0.001 "" \ white black 27 27 0 simundump kreac /kinetics/chain/kinetics[6]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 18 30 0 simundump kpool /kinetics/chain/kinetics[6]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 22.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[6]/CaM/CaM-Ca2/diff 0 0.101 0.001 "" \ white black 23.999 30.258 0 simundump kreac /kinetics/chain/kinetics[6]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 19.158 26.225 0 simundump kreac /kinetics/chain/kinetics[6]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 24 30 0 simundump kpool /kinetics/chain/kinetics[6]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 21 31 0 simundump kreac /kinetics/chain/kinetics[6]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 22 34 0 simundump kpool /kinetics/chain/kinetics[6]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 10 23 0 simundump kreac /kinetics/chain/kinetics[6]/Ca/diff 0 0.101 0.001 "" white \ black 11 26 0 simundump kreac /kinetics/chain/kinetics[6]/Ras-act-unphosph-raf 0 0 0 "" \ white black 32 8 0 simundump group /kinetics/chain/kinetics[6]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 21 19 0 simundump kpool /kinetics/chain/kinetics[6]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 17 17 0 simundump kreac /kinetics/chain/kinetics[6]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 18 20 0 simundump kpool /kinetics/chain/kinetics[6]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 17 9 0 simundump kenz /kinetics/chain/kinetics[6]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 18 10 0 simundump kreac /kinetics/chain/kinetics[6]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 18 12 0 simundump kpool /kinetics/chain/kinetics[6]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 21 12 0 simundump kreac /kinetics/chain/kinetics[6]/PKM/PKM_degradation 0 0.0005 0 "" \ white 25 20 7 0 simundump kpool /kinetics/chain/kinetics[6]/PKM/degraded_PKM 0 -1e-12 0 0 0 0 \ 0 0 75396 4 /kinetics/dendgeom 7 25 16 5 0 simundump kpool /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 16 \ 14 0 simundump kenz /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 16 13 0 simundump kreac /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 17 17 0 simundump kpool /kinetics/chain/kinetics[6]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 13 12 0 simundump kreac /kinetics/chain/kinetics[6]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 14 15 0 simundump kreac /kinetics/chain/kinetics[6]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 11 9 0 simundump kreac /kinetics/chain/kinetics[6]/PKM/trigger_PKM 0 0.00013263 1 "" \ white 25 11 16 0 simundump kpool /kinetics/chain/kinetics[6]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 10 30 0 simundump kreac /kinetics/chain/kinetics[6]/Ca_diff 0 5 5 "" white black 10 \ 26 0 simundump group /kinetics/chain/kinetics[7] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 32 0 0 simundump group /kinetics/chain/kinetics[7]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 28.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[7]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 27.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[7]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 28.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[7]/PKC/PKC-act-by-Ca 0 7.958e-06 0.5 \ "" white blue 27.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[7]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 29.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[7]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 28.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[7]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 29.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[7]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 29.221 6.529 0 simundump kreac /kinetics/chain/kinetics[7]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 30.221 9.529 0 simundump kpool /kinetics/chain/kinetics[7]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 30.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[7]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 31.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 32.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG/diff 0 0.101 0.001 \ "" white black 33.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[7]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 28.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[7]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 31.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[7]/PKC/PKC-DAG/diff 0 0.101 0.001 "" \ white black 32.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic 0 -1e-12 0.8223 \ 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 25.868 0.59711 \ 0 simundump kreac /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 26.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[7]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 29 11 0 simundump kreac /kinetics/chain/kinetics[7]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 30 14 0 simundump kpool /kinetics/chain/kinetics[7]/DAG 1 -1e-12 12.2 12.2 9.1983e+05 \ 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 36 -3 0 simundump kpool /kinetics/chain/kinetics[7]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 32 9 0 simundump kenz /kinetics/chain/kinetics[7]/PKC-active/PKC-act-raf 1 0.0011493 \ 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow "" 38 10 0 simundump kenz /kinetics/chain/kinetics[7]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 36 13 0 simundump kenz /kinetics/chain/kinetics[7]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 41 20 0 simundump kpool /kinetics/chain/kinetics[7]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 45 1 \ 0 simundump kenz /kinetics/chain/kinetics[7]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 42 \ 10 0 simundump kreac /kinetics/chain/kinetics[7]/MAPK*/diff 0 0.101 0.001 "" white \ black 46 4 0 simundump group /kinetics/chain/kinetics[7]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 47 11 0 simundump kpool /kinetics/chain/kinetics[7]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 38 8 0 simundump kreac /kinetics/chain/kinetics[7]/MAPK/craf-1/diff 0 0.101 0.001 "" \ white black 39 11 0 simundump kpool /kinetics/chain/kinetics[7]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 41 8 0 simundump kreac /kinetics/chain/kinetics[7]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 42 11 0 simundump kpool /kinetics/chain/kinetics[7]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 38 4 0 simundump kreac /kinetics/chain/kinetics[7]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 39 7 0 simundump kpool /kinetics/chain/kinetics[7]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 38 1 0 simundump kreac /kinetics/chain/kinetics[7]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 39 4 0 simundump kpool /kinetics/chain/kinetics[7]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 44 8 0 simundump kreac /kinetics/chain/kinetics[7]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 45 11 0 simundump kpool /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 41 1 0 simundump kreac /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 42 4 0 simundump kpool /kinetics/chain/kinetics[7]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 45 4 0 simundump kenz /kinetics/chain/kinetics[7]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 40 3 0 simundump kenz /kinetics/chain/kinetics[7]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 45 3 \ 0 simundump kreac /kinetics/chain/kinetics[7]/MAPK/MAPKK*/diff 0 0.101 0.001 "" \ white black 46 7 0 simundump kpool /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 41 4 0 simundump kreac /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser/diff 0 0.101 0.001 \ "" white black 42 7 0 simundump kpool /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 37 6 0 simundump kenz /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 40 6 0 simundump kenz /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 43 6 0 simundump kreac /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 38 9 0 simundump kpool /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 37 5 0 simundump kenz /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 40 \ 5 0 simundump kenz /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 43 5 0 simundump kreac /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 38 8 0 simundump kpool /kinetics/chain/kinetics[7]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 37 2 0 simundump kenz /kinetics/chain/kinetics[7]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 38 3 0 simundump kenz /kinetics/chain/kinetics[7]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 43 \ 3 0 simundump kreac /kinetics/chain/kinetics[7]/MKP-1/diff 0 0.101 0.001 "" white \ black 38 5 0 simundump kreac /kinetics/chain/kinetics[7]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 35 9 0 simundump kpool /kinetics/chain/kinetics[7]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 41 9 0 simundump kenz /kinetics/chain/kinetics[7]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 40 10 0 simundump kenz /kinetics/chain/kinetics[7]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 43 7 0 simundump kenz /kinetics/chain/kinetics[7]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 40 7 0 simundump kenz /kinetics/chain/kinetics[7]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 44 10 0 simundump kreac /kinetics/chain/kinetics[7]/PPhosphatase2A/diff 0 0.101 0.001 \ "" white black 42 12 0 simundump group /kinetics/chain/kinetics[7]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 46.513 16.351 0 simundump kreac /kinetics/chain/kinetics[7]/Ras/dephosph-GEF 1 1 0 "" white \ blue 41.07 17.881 0 simundump kpool /kinetics/chain/kinetics[7]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 44.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[7]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 44 17 0 simundump kreac /kinetics/chain/kinetics[7]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 45.453 21.352 0 simundump kpool /kinetics/chain/kinetics[7]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 38.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[7]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 39.085 16.086 0 simundump kreac /kinetics/chain/kinetics[7]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 39.448 20.246 0 simundump kpool /kinetics/chain/kinetics[7]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 44.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[7]/Ras/GTP-Ras/diff 0 0.101 0.001 "" \ white black 45.564 16.084 0 simundump kpool /kinetics/chain/kinetics[7]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 38.131 14.165 0 simundump kreac /kinetics/chain/kinetics[7]/Ras/GDP-Ras/diff 0 0.101 0.001 "" \ white black 39.131 17.165 0 simundump kreac /kinetics/chain/kinetics[7]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 41.098 13.5 0 simundump kreac /kinetics/chain/kinetics[7]/Ras/dephosph-GAP 1 0.1 0 "" white \ blue 36.023 15.524 0 simundump kpool /kinetics/chain/kinetics[7]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 33.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[7]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 34.35 17.349 0 simundump kpool /kinetics/chain/kinetics[7]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 38.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[7]/Ras/GAP/GAP-inact-ras 1 2.1491e-05 \ 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red "" 41.012 \ 12.403 0 simundump kreac /kinetics/chain/kinetics[7]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 39.655 15.338 0 simundump kreac /kinetics/chain/kinetics[7]/Ras/CaM-bind-GEF 1 0.0026526 1 "" \ white blue 34.486 21.679 0 simundump kpool /kinetics/chain/kinetics[7]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 37.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[7]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 37.022 18.657 0 simundump kreac /kinetics/chain/kinetics[7]/Ras/CaM-GEF/diff 0 0.101 0.001 "" \ white black 38.345 22.58 0 simundump group /kinetics/chain/kinetics[7]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 22 21 0 simundump kpool /kinetics/chain/kinetics[7]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 19 30 0 simundump kreac /kinetics/chain/kinetics[7]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 20 33 0 simundump kreac /kinetics/chain/kinetics[7]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 21.6 23.26 0 simundump kpool /kinetics/chain/kinetics[7]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 25.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[7]/CaM/CaM-Ca3/diff 0 0.101 0.001 "" \ white black 26.489 27.397 0 simundump kpool /kinetics/chain/kinetics[7]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 30 24 0 simundump kreac /kinetics/chain/kinetics[7]/CaM/CaM-Ca4/diff 0 0.101 0.001 "" \ white black 31 27 0 simundump kreac /kinetics/chain/kinetics[7]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 22 30 0 simundump kpool /kinetics/chain/kinetics[7]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 26.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[7]/CaM/CaM-Ca2/diff 0 0.101 0.001 "" \ white black 27.999 30.258 0 simundump kreac /kinetics/chain/kinetics[7]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 23.158 26.225 0 simundump kreac /kinetics/chain/kinetics[7]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 28 30 0 simundump kpool /kinetics/chain/kinetics[7]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 25 31 0 simundump kreac /kinetics/chain/kinetics[7]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 26 34 0 simundump kpool /kinetics/chain/kinetics[7]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 14 23 0 simundump kreac /kinetics/chain/kinetics[7]/Ca/diff 0 0.101 0.001 "" white \ black 15 26 0 simundump kreac /kinetics/chain/kinetics[7]/Ras-act-unphosph-raf 0 0 0 "" \ white black 36 8 0 simundump group /kinetics/chain/kinetics[7]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 25 19 0 simundump kpool /kinetics/chain/kinetics[7]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 21 17 0 simundump kreac /kinetics/chain/kinetics[7]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 22 20 0 simundump kpool /kinetics/chain/kinetics[7]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 21 9 0 simundump kenz /kinetics/chain/kinetics[7]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 22 10 0 simundump kreac /kinetics/chain/kinetics[7]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 22 12 0 simundump kpool /kinetics/chain/kinetics[7]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 25 12 0 simundump kreac /kinetics/chain/kinetics[7]/PKM/PKM_degradation 0 0.0005 0 "" \ white 25 24 7 0 simundump kpool /kinetics/chain/kinetics[7]/PKM/degraded_PKM 0 -1e-12 0 0 0 0 \ 0 0 75396 4 /kinetics/dendgeom 7 25 20 5 0 simundump kpool /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 20 \ 14 0 simundump kenz /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 20 13 0 simundump kreac /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 21 17 0 simundump kpool /kinetics/chain/kinetics[7]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 17 12 0 simundump kreac /kinetics/chain/kinetics[7]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 18 15 0 simundump kreac /kinetics/chain/kinetics[7]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 15 9 0 simundump kreac /kinetics/chain/kinetics[7]/PKM/trigger_PKM 0 0.00013263 1 "" \ white 25 15 16 0 simundump kpool /kinetics/chain/kinetics[7]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 14 30 0 simundump kreac /kinetics/chain/kinetics[7]/Ca_diff 0 5 5 "" white black 14 \ 26 0 simundump group /kinetics/chain/kinetics[8] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 36 0 0 simundump group /kinetics/chain/kinetics[8]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 32.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[8]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 31.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[8]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 32.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[8]/PKC/PKC-act-by-Ca 0 7.958e-06 0.5 \ "" white blue 31.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[8]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 33.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[8]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 32.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[8]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 33.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[8]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 33.221 6.529 0 simundump kreac /kinetics/chain/kinetics[8]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 34.221 9.529 0 simundump kpool /kinetics/chain/kinetics[8]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 34.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[8]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 35.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 36.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG/diff 0 0.101 0.001 \ "" white black 37.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[8]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 32.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[8]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 35.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[8]/PKC/PKC-DAG/diff 0 0.101 0.001 "" \ white black 36.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic 0 -1e-12 0.8223 \ 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 29.868 0.59711 \ 0 simundump kreac /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 30.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[8]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 33 11 0 simundump kreac /kinetics/chain/kinetics[8]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 34 14 0 simundump kpool /kinetics/chain/kinetics[8]/DAG 1 -1e-12 12.2 12.2 9.1983e+05 \ 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 40 -3 0 simundump kpool /kinetics/chain/kinetics[8]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 36 9 0 simundump kenz /kinetics/chain/kinetics[8]/PKC-active/PKC-act-raf 1 0.0011493 \ 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow "" 42 10 0 simundump kenz /kinetics/chain/kinetics[8]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 40 13 0 simundump kenz /kinetics/chain/kinetics[8]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 45 20 0 simundump kpool /kinetics/chain/kinetics[8]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 49 1 \ 0 simundump kenz /kinetics/chain/kinetics[8]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 46 \ 10 0 simundump kreac /kinetics/chain/kinetics[8]/MAPK*/diff 0 0.101 0.001 "" white \ black 50 4 0 simundump group /kinetics/chain/kinetics[8]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 51 11 0 simundump kpool /kinetics/chain/kinetics[8]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 42 8 0 simundump kreac /kinetics/chain/kinetics[8]/MAPK/craf-1/diff 0 0.101 0.001 "" \ white black 43 11 0 simundump kpool /kinetics/chain/kinetics[8]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 45 8 0 simundump kreac /kinetics/chain/kinetics[8]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 46 11 0 simundump kpool /kinetics/chain/kinetics[8]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 42 4 0 simundump kreac /kinetics/chain/kinetics[8]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 43 7 0 simundump kpool /kinetics/chain/kinetics[8]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 42 1 0 simundump kreac /kinetics/chain/kinetics[8]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 43 4 0 simundump kpool /kinetics/chain/kinetics[8]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 48 8 0 simundump kreac /kinetics/chain/kinetics[8]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 49 11 0 simundump kpool /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 45 1 0 simundump kreac /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 46 4 0 simundump kpool /kinetics/chain/kinetics[8]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 49 4 0 simundump kenz /kinetics/chain/kinetics[8]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 44 3 0 simundump kenz /kinetics/chain/kinetics[8]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 49 3 \ 0 simundump kreac /kinetics/chain/kinetics[8]/MAPK/MAPKK*/diff 0 0.101 0.001 "" \ white black 50 7 0 simundump kpool /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 45 4 0 simundump kreac /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser/diff 0 0.101 0.001 \ "" white black 46 7 0 simundump kpool /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 41 6 0 simundump kenz /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 44 6 0 simundump kenz /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 47 6 0 simundump kreac /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 42 9 0 simundump kpool /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 41 5 0 simundump kenz /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 44 \ 5 0 simundump kenz /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 47 5 0 simundump kreac /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 42 8 0 simundump kpool /kinetics/chain/kinetics[8]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 41 2 0 simundump kenz /kinetics/chain/kinetics[8]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 42 3 0 simundump kenz /kinetics/chain/kinetics[8]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 47 \ 3 0 simundump kreac /kinetics/chain/kinetics[8]/MKP-1/diff 0 0.101 0.001 "" white \ black 42 5 0 simundump kreac /kinetics/chain/kinetics[8]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 39 9 0 simundump kpool /kinetics/chain/kinetics[8]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 45 9 0 simundump kenz /kinetics/chain/kinetics[8]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 44 10 0 simundump kenz /kinetics/chain/kinetics[8]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 47 7 0 simundump kenz /kinetics/chain/kinetics[8]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 44 7 0 simundump kenz /kinetics/chain/kinetics[8]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 48 10 0 simundump kreac /kinetics/chain/kinetics[8]/PPhosphatase2A/diff 0 0.101 0.001 \ "" white black 46 12 0 simundump group /kinetics/chain/kinetics[8]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 50.513 16.351 0 simundump kreac /kinetics/chain/kinetics[8]/Ras/dephosph-GEF 1 1 0 "" white \ blue 45.07 17.881 0 simundump kpool /kinetics/chain/kinetics[8]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 48.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[8]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 48 17 0 simundump kreac /kinetics/chain/kinetics[8]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 49.453 21.352 0 simundump kpool /kinetics/chain/kinetics[8]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 42.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[8]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 43.085 16.086 0 simundump kreac /kinetics/chain/kinetics[8]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 43.448 20.246 0 simundump kpool /kinetics/chain/kinetics[8]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 48.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[8]/Ras/GTP-Ras/diff 0 0.101 0.001 "" \ white black 49.564 16.084 0 simundump kpool /kinetics/chain/kinetics[8]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 42.131 14.165 0 simundump kreac /kinetics/chain/kinetics[8]/Ras/GDP-Ras/diff 0 0.101 0.001 "" \ white black 43.131 17.165 0 simundump kreac /kinetics/chain/kinetics[8]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 45.098 13.5 0 simundump kreac /kinetics/chain/kinetics[8]/Ras/dephosph-GAP 1 0.1 0 "" white \ blue 40.023 15.524 0 simundump kpool /kinetics/chain/kinetics[8]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 37.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[8]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 38.35 17.349 0 simundump kpool /kinetics/chain/kinetics[8]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 42.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[8]/Ras/GAP/GAP-inact-ras 1 2.1491e-05 \ 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red "" 45.012 \ 12.403 0 simundump kreac /kinetics/chain/kinetics[8]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 43.655 15.338 0 simundump kreac /kinetics/chain/kinetics[8]/Ras/CaM-bind-GEF 1 0.0026526 1 "" \ white blue 38.486 21.679 0 simundump kpool /kinetics/chain/kinetics[8]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 41.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[8]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 41.022 18.657 0 simundump kreac /kinetics/chain/kinetics[8]/Ras/CaM-GEF/diff 0 0.101 0.001 "" \ white black 42.345 22.58 0 simundump group /kinetics/chain/kinetics[8]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 26 21 0 simundump kpool /kinetics/chain/kinetics[8]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 23 30 0 simundump kreac /kinetics/chain/kinetics[8]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 24 33 0 simundump kreac /kinetics/chain/kinetics[8]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 25.6 23.26 0 simundump kpool /kinetics/chain/kinetics[8]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 29.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[8]/CaM/CaM-Ca3/diff 0 0.101 0.001 "" \ white black 30.489 27.397 0 simundump kpool /kinetics/chain/kinetics[8]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 34 24 0 simundump kreac /kinetics/chain/kinetics[8]/CaM/CaM-Ca4/diff 0 0.101 0.001 "" \ white black 35 27 0 simundump kreac /kinetics/chain/kinetics[8]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 26 30 0 simundump kpool /kinetics/chain/kinetics[8]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 30.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[8]/CaM/CaM-Ca2/diff 0 0.101 0.001 "" \ white black 31.999 30.258 0 simundump kreac /kinetics/chain/kinetics[8]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 27.158 26.225 0 simundump kreac /kinetics/chain/kinetics[8]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 32 30 0 simundump kpool /kinetics/chain/kinetics[8]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 29 31 0 simundump kreac /kinetics/chain/kinetics[8]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 30 34 0 simundump kpool /kinetics/chain/kinetics[8]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 18 23 0 simundump kreac /kinetics/chain/kinetics[8]/Ca/diff 0 0.101 0.001 "" white \ black 19 26 0 simundump kreac /kinetics/chain/kinetics[8]/Ras-act-unphosph-raf 0 0 0 "" \ white black 40 8 0 simundump group /kinetics/chain/kinetics[8]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 29 19 0 simundump kpool /kinetics/chain/kinetics[8]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 25 17 0 simundump kreac /kinetics/chain/kinetics[8]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 26 20 0 simundump kpool /kinetics/chain/kinetics[8]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 25 9 0 simundump kenz /kinetics/chain/kinetics[8]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 26 10 0 simundump kreac /kinetics/chain/kinetics[8]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 26 12 0 simundump kpool /kinetics/chain/kinetics[8]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 29 12 0 simundump kreac /kinetics/chain/kinetics[8]/PKM/PKM_degradation 0 0.0005 0 "" \ white 25 28 7 0 simundump kpool /kinetics/chain/kinetics[8]/PKM/degraded_PKM 0 -1e-12 0 0 0 0 \ 0 0 75396 4 /kinetics/dendgeom 7 25 24 5 0 simundump kpool /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 24 \ 14 0 simundump kenz /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 24 13 0 simundump kreac /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 25 17 0 simundump kpool /kinetics/chain/kinetics[8]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 21 12 0 simundump kreac /kinetics/chain/kinetics[8]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 22 15 0 simundump kreac /kinetics/chain/kinetics[8]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 19 9 0 simundump kreac /kinetics/chain/kinetics[8]/PKM/trigger_PKM 0 0.00013263 1 "" \ white 25 19 16 0 simundump kpool /kinetics/chain/kinetics[8]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 18 30 0 simundump kreac /kinetics/chain/kinetics[8]/Ca_diff 0 5 5 "" white black 18 \ 26 0 simundump group /kinetics/chain/kinetics[9] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 40 0 0 simundump group /kinetics/chain/kinetics[9]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 36.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[9]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 35.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[9]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 36.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[9]/PKC/PKC-act-by-Ca 0 7.958e-06 0.5 \ "" white blue 35.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[9]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 37.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[9]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 36.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[9]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 37.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[9]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 37.221 6.529 0 simundump kreac /kinetics/chain/kinetics[9]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 38.221 9.529 0 simundump kpool /kinetics/chain/kinetics[9]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 38.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[9]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 39.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[9]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 40.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[9]/PKC/PKC-Ca-DAG/diff 0 0.101 0.001 \ "" white black 41.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[9]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 36.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[9]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 39.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[9]/PKC/PKC-DAG/diff 0 0.101 0.001 "" \ white black 40.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[9]/PKC/PKC-cytosolic 0 -1e-12 0.8223 \ 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 33.868 0.59711 \ 0 simundump kreac /kinetics/chain/kinetics[9]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 34.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[9]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 37 11 0 simundump kreac /kinetics/chain/kinetics[9]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 38 14 0 simundump kpool /kinetics/chain/kinetics[9]/DAG 1 -1e-12 12.2 12.2 9.1983e+05 \ 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 44 -3 0 simundump kpool /kinetics/chain/kinetics[9]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 40 9 0 simundump kenz /kinetics/chain/kinetics[9]/PKC-active/PKC-act-raf 1 0.0011493 \ 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow "" 46 10 0 simundump kenz /kinetics/chain/kinetics[9]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 44 13 0 simundump kenz /kinetics/chain/kinetics[9]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 49 20 0 simundump kpool /kinetics/chain/kinetics[9]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 53 1 \ 0 simundump kenz /kinetics/chain/kinetics[9]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 50 \ 10 0 simundump kreac /kinetics/chain/kinetics[9]/MAPK*/diff 0 0.101 0.001 "" white \ black 54 4 0 simundump group /kinetics/chain/kinetics[9]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 55 11 0 simundump kpool /kinetics/chain/kinetics[9]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 46 8 0 simundump kreac /kinetics/chain/kinetics[9]/MAPK/craf-1/diff 0 0.101 0.001 "" \ white black 47 11 0 simundump kpool /kinetics/chain/kinetics[9]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 49 8 0 simundump kreac /kinetics/chain/kinetics[9]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 50 11 0 simundump kpool /kinetics/chain/kinetics[9]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 46 4 0 simundump kreac /kinetics/chain/kinetics[9]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 47 7 0 simundump kpool /kinetics/chain/kinetics[9]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 46 1 0 simundump kreac /kinetics/chain/kinetics[9]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 47 4 0 simundump kpool /kinetics/chain/kinetics[9]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 52 8 0 simundump kreac /kinetics/chain/kinetics[9]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 53 11 0 simundump kpool /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 49 1 0 simundump kreac /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 50 4 0 simundump kpool /kinetics/chain/kinetics[9]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 53 4 0 simundump kenz /kinetics/chain/kinetics[9]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 48 3 0 simundump kenz /kinetics/chain/kinetics[9]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 53 3 \ 0 simundump kreac /kinetics/chain/kinetics[9]/MAPK/MAPKK*/diff 0 0.101 0.001 "" \ white black 54 7 0 simundump kpool /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 49 4 0 simundump kreac /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser/diff 0 0.101 0.001 \ "" white black 50 7 0 simundump kpool /kinetics/chain/kinetics[9]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 45 6 0 simundump kenz /kinetics/chain/kinetics[9]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 48 6 0 simundump kenz /kinetics/chain/kinetics[9]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 0 \ 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 51 6 0 simundump kreac /kinetics/chain/kinetics[9]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 46 9 0 simundump kpool /kinetics/chain/kinetics[9]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 45 5 0 simundump kenz /kinetics/chain/kinetics[9]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 48 \ 5 0 simundump kenz /kinetics/chain/kinetics[9]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 51 5 0 simundump kreac /kinetics/chain/kinetics[9]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 46 8 0 simundump kpool /kinetics/chain/kinetics[9]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 45 2 0 simundump kenz /kinetics/chain/kinetics[9]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 46 3 0 simundump kenz /kinetics/chain/kinetics[9]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 51 \ 3 0 simundump kreac /kinetics/chain/kinetics[9]/MKP-1/diff 0 0.101 0.001 "" white \ black 46 5 0 simundump kreac /kinetics/chain/kinetics[9]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 43 9 0 simundump kpool /kinetics/chain/kinetics[9]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 49 9 0 simundump kenz /kinetics/chain/kinetics[9]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 48 10 0 simundump kenz /kinetics/chain/kinetics[9]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 51 7 0 simundump kenz /kinetics/chain/kinetics[9]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 48 7 0 simundump kenz /kinetics/chain/kinetics[9]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 52 10 0 simundump kreac /kinetics/chain/kinetics[9]/PPhosphatase2A/diff 0 0.101 0.001 \ "" white black 50 12 0 simundump group /kinetics/chain/kinetics[9]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 54.513 16.351 0 simundump kreac /kinetics/chain/kinetics[9]/Ras/dephosph-GEF 1 1 0 "" white \ blue 49.07 17.881 0 simundump kpool /kinetics/chain/kinetics[9]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 52.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[9]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 52 17 0 simundump kreac /kinetics/chain/kinetics[9]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 53.453 21.352 0 simundump kpool /kinetics/chain/kinetics[9]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 46.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[9]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 47.085 16.086 0 simundump kreac /kinetics/chain/kinetics[9]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 47.448 20.246 0 simundump kpool /kinetics/chain/kinetics[9]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 52.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[9]/Ras/GTP-Ras/diff 0 0.101 0.001 "" \ white black 53.564 16.084 0 simundump kpool /kinetics/chain/kinetics[9]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 46.131 14.165 0 simundump kreac /kinetics/chain/kinetics[9]/Ras/GDP-Ras/diff 0 0.101 0.001 "" \ white black 47.131 17.165 0 simundump kreac /kinetics/chain/kinetics[9]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 49.098 13.5 0 simundump kreac /kinetics/chain/kinetics[9]/Ras/dephosph-GAP 1 0.1 0 "" white \ blue 44.023 15.524 0 simundump kpool /kinetics/chain/kinetics[9]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 41.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[9]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 42.35 17.349 0 simundump kpool /kinetics/chain/kinetics[9]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 46.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[9]/Ras/GAP/GAP-inact-ras 1 2.1491e-05 \ 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red "" 49.012 \ 12.403 0 simundump kreac /kinetics/chain/kinetics[9]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 47.655 15.338 0 simundump kreac /kinetics/chain/kinetics[9]/Ras/CaM-bind-GEF 1 0.0026526 1 "" \ white blue 42.486 21.679 0 simundump kpool /kinetics/chain/kinetics[9]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 45.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[9]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 45.022 18.657 0 simundump kreac /kinetics/chain/kinetics[9]/Ras/CaM-GEF/diff 0 0.101 0.001 "" \ white black 46.345 22.58 0 simundump group /kinetics/chain/kinetics[9]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 30 21 0 simundump kpool /kinetics/chain/kinetics[9]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 27 30 0 simundump kreac /kinetics/chain/kinetics[9]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 28 33 0 simundump kreac /kinetics/chain/kinetics[9]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 29.6 23.26 0 simundump kpool /kinetics/chain/kinetics[9]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 33.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[9]/CaM/CaM-Ca3/diff 0 0.101 0.001 "" \ white black 34.489 27.397 0 simundump kpool /kinetics/chain/kinetics[9]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 38 24 0 simundump kreac /kinetics/chain/kinetics[9]/CaM/CaM-Ca4/diff 0 0.101 0.001 "" \ white black 39 27 0 simundump kreac /kinetics/chain/kinetics[9]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 30 30 0 simundump kpool /kinetics/chain/kinetics[9]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 34.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[9]/CaM/CaM-Ca2/diff 0 0.101 0.001 "" \ white black 35.999 30.258 0 simundump kreac /kinetics/chain/kinetics[9]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 31.158 26.225 0 simundump kreac /kinetics/chain/kinetics[9]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 36 30 0 simundump kpool /kinetics/chain/kinetics[9]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 33 31 0 simundump kreac /kinetics/chain/kinetics[9]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 34 34 0 simundump kpool /kinetics/chain/kinetics[9]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 22 23 0 simundump kreac /kinetics/chain/kinetics[9]/Ca/diff 0 0.101 0.001 "" white \ black 23 26 0 simundump kreac /kinetics/chain/kinetics[9]/Ras-act-unphosph-raf 0 0 0 "" \ white black 44 8 0 simundump group /kinetics/chain/kinetics[9]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 33 19 0 simundump kpool /kinetics/chain/kinetics[9]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 29 17 0 simundump kreac /kinetics/chain/kinetics[9]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 30 20 0 simundump kpool /kinetics/chain/kinetics[9]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 29 9 0 simundump kenz /kinetics/chain/kinetics[9]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 30 10 0 simundump kreac /kinetics/chain/kinetics[9]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 30 12 0 simundump kpool /kinetics/chain/kinetics[9]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 33 12 0 simundump kreac /kinetics/chain/kinetics[9]/PKM/PKM_degradation 0 0.0005 0 "" \ white 25 32 7 0 simundump kpool /kinetics/chain/kinetics[9]/PKM/degraded_PKM 0 -1e-12 0 0 0 0 \ 0 0 75396 4 /kinetics/dendgeom 7 25 28 5 0 simundump kpool /kinetics/chain/kinetics[9]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 28 \ 14 0 simundump kenz /kinetics/chain/kinetics[9]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 28 13 0 simundump kreac /kinetics/chain/kinetics[9]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 29 17 0 simundump kpool /kinetics/chain/kinetics[9]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 25 12 0 simundump kreac /kinetics/chain/kinetics[9]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 26 15 0 simundump kreac /kinetics/chain/kinetics[9]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 23 9 0 simundump kreac /kinetics/chain/kinetics[9]/PKM/trigger_PKM 0 0.00013263 1 "" \ white 25 23 16 0 simundump kpool /kinetics/chain/kinetics[9]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 22 30 0 simundump kreac /kinetics/chain/kinetics[9]/Ca_diff 0 5 5 "" white black 22 \ 26 0 simundump group /kinetics/chain/kinetics[10] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 44 0 0 simundump group /kinetics/chain/kinetics[10]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 40.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[10]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 39.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[10]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 40.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[10]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 39.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[10]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 41.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[10]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 40.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[10]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 41.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[10]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 41.221 6.529 0 simundump kreac /kinetics/chain/kinetics[10]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 42.221 9.529 0 simundump kpool /kinetics/chain/kinetics[10]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 42.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[10]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 43.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[10]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 44.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[10]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 45.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[10]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 40.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[10]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 43.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[10]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 44.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[10]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 37.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[10]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 38.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[10]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 41 11 0 simundump kreac /kinetics/chain/kinetics[10]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 42 14 0 simundump kpool /kinetics/chain/kinetics[10]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 48 -3 0 simundump kpool /kinetics/chain/kinetics[10]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 44 9 0 simundump kenz /kinetics/chain/kinetics[10]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 50 10 0 simundump kenz /kinetics/chain/kinetics[10]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 48 13 0 simundump kenz /kinetics/chain/kinetics[10]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 53 20 0 simundump kpool /kinetics/chain/kinetics[10]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 57 1 \ 0 simundump kenz /kinetics/chain/kinetics[10]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 54 \ 10 0 simundump kreac /kinetics/chain/kinetics[10]/MAPK*/diff 0 0.101 0.001 "" \ white black 58 4 0 simundump group /kinetics/chain/kinetics[10]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 59 11 0 simundump kpool /kinetics/chain/kinetics[10]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 50 8 0 simundump kreac /kinetics/chain/kinetics[10]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 51 11 0 simundump kpool /kinetics/chain/kinetics[10]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 53 8 0 simundump kreac /kinetics/chain/kinetics[10]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 54 11 0 simundump kpool /kinetics/chain/kinetics[10]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 50 4 0 simundump kreac /kinetics/chain/kinetics[10]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 51 7 0 simundump kpool /kinetics/chain/kinetics[10]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 50 1 0 simundump kreac /kinetics/chain/kinetics[10]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 51 4 0 simundump kpool /kinetics/chain/kinetics[10]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 56 8 0 simundump kreac /kinetics/chain/kinetics[10]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 57 11 0 simundump kpool /kinetics/chain/kinetics[10]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 53 1 0 simundump kreac /kinetics/chain/kinetics[10]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 54 4 0 simundump kpool /kinetics/chain/kinetics[10]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 57 4 0 simundump kenz /kinetics/chain/kinetics[10]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 52 3 0 simundump kenz /kinetics/chain/kinetics[10]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 57 3 \ 0 simundump kreac /kinetics/chain/kinetics[10]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 58 7 0 simundump kpool /kinetics/chain/kinetics[10]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 53 4 0 simundump kreac /kinetics/chain/kinetics[10]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 54 7 0 simundump kpool /kinetics/chain/kinetics[10]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 49 6 0 simundump kenz /kinetics/chain/kinetics[10]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 52 6 0 simundump kenz /kinetics/chain/kinetics[10]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 55 6 0 simundump kreac /kinetics/chain/kinetics[10]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 50 9 0 simundump kpool /kinetics/chain/kinetics[10]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 49 5 0 simundump kenz /kinetics/chain/kinetics[10]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 52 \ 5 0 simundump kenz /kinetics/chain/kinetics[10]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 55 5 0 simundump kreac /kinetics/chain/kinetics[10]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 50 8 0 simundump kpool /kinetics/chain/kinetics[10]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 49 2 0 simundump kenz /kinetics/chain/kinetics[10]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 50 3 0 simundump kenz /kinetics/chain/kinetics[10]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 55 \ 3 0 simundump kreac /kinetics/chain/kinetics[10]/MKP-1/diff 0 0.101 0.001 "" \ white black 50 5 0 simundump kreac /kinetics/chain/kinetics[10]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 47 9 0 simundump kpool /kinetics/chain/kinetics[10]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 53 9 0 simundump kenz /kinetics/chain/kinetics[10]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 52 10 0 simundump kenz /kinetics/chain/kinetics[10]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 55 7 0 simundump kenz /kinetics/chain/kinetics[10]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 52 7 0 simundump kenz /kinetics/chain/kinetics[10]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 56 10 0 simundump kreac /kinetics/chain/kinetics[10]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 54 12 0 simundump group /kinetics/chain/kinetics[10]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 58.513 16.351 0 simundump kreac /kinetics/chain/kinetics[10]/Ras/dephosph-GEF 1 1 0 "" white \ blue 53.07 17.881 0 simundump kpool /kinetics/chain/kinetics[10]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 56.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[10]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 56 17 0 simundump kreac /kinetics/chain/kinetics[10]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 57.453 21.352 0 simundump kpool /kinetics/chain/kinetics[10]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 50.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[10]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 51.085 16.086 0 simundump kreac /kinetics/chain/kinetics[10]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 51.448 20.246 0 simundump kpool /kinetics/chain/kinetics[10]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 56.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[10]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 57.564 16.084 0 simundump kpool /kinetics/chain/kinetics[10]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 50.131 14.165 0 simundump kreac /kinetics/chain/kinetics[10]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 51.131 17.165 0 simundump kreac /kinetics/chain/kinetics[10]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 53.098 13.5 0 simundump kreac /kinetics/chain/kinetics[10]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 48.023 15.524 0 simundump kpool /kinetics/chain/kinetics[10]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 45.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[10]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 46.35 17.349 0 simundump kpool /kinetics/chain/kinetics[10]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 50.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[10]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 53.012 12.403 0 simundump kreac /kinetics/chain/kinetics[10]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 51.655 15.338 0 simundump kreac /kinetics/chain/kinetics[10]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 46.486 21.679 0 simundump kpool /kinetics/chain/kinetics[10]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 49.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[10]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 49.022 18.657 0 simundump kreac /kinetics/chain/kinetics[10]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 50.345 22.58 0 simundump group /kinetics/chain/kinetics[10]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 34 21 0 simundump kpool /kinetics/chain/kinetics[10]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 31 30 0 simundump kreac /kinetics/chain/kinetics[10]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 32 33 0 simundump kreac /kinetics/chain/kinetics[10]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 33.6 23.26 0 simundump kpool /kinetics/chain/kinetics[10]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 37.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[10]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 38.489 27.397 0 simundump kpool /kinetics/chain/kinetics[10]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 42 24 0 simundump kreac /kinetics/chain/kinetics[10]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 43 27 0 simundump kreac /kinetics/chain/kinetics[10]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 34 30 0 simundump kpool /kinetics/chain/kinetics[10]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 38.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[10]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 39.999 30.258 0 simundump kreac /kinetics/chain/kinetics[10]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 35.158 26.225 0 simundump kreac /kinetics/chain/kinetics[10]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 40 30 0 simundump kpool /kinetics/chain/kinetics[10]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 37 31 0 simundump kreac /kinetics/chain/kinetics[10]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 38 34 0 simundump kpool /kinetics/chain/kinetics[10]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 26 23 0 simundump kreac /kinetics/chain/kinetics[10]/Ca/diff 0 0.101 0.001 "" white \ black 27 26 0 simundump kreac /kinetics/chain/kinetics[10]/Ras-act-unphosph-raf 0 0 0 "" \ white black 48 8 0 simundump group /kinetics/chain/kinetics[10]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 37 19 0 simundump kpool /kinetics/chain/kinetics[10]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 33 17 0 simundump kreac /kinetics/chain/kinetics[10]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 34 20 0 simundump kpool /kinetics/chain/kinetics[10]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 33 9 0 simundump kenz /kinetics/chain/kinetics[10]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 34 10 0 simundump kreac /kinetics/chain/kinetics[10]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 34 12 0 simundump kpool /kinetics/chain/kinetics[10]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 37 12 0 simundump kreac /kinetics/chain/kinetics[10]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 36 7 0 simundump kpool /kinetics/chain/kinetics[10]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 32 5 0 simundump kpool /kinetics/chain/kinetics[10]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 32 \ 14 0 simundump kenz /kinetics/chain/kinetics[10]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 32 13 0 simundump kreac /kinetics/chain/kinetics[10]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 33 17 0 simundump kpool /kinetics/chain/kinetics[10]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 29 12 0 simundump kreac /kinetics/chain/kinetics[10]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 30 15 0 simundump kreac /kinetics/chain/kinetics[10]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 27 9 0 simundump kreac /kinetics/chain/kinetics[10]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 27 16 0 simundump kpool /kinetics/chain/kinetics[10]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 26 30 0 simundump kreac /kinetics/chain/kinetics[10]/Ca_diff 0 5 5 "" white black 26 \ 26 0 simundump group /kinetics/chain/kinetics[11] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 48 0 0 simundump group /kinetics/chain/kinetics[11]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 44.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[11]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 43.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[11]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 44.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[11]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 43.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[11]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 45.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[11]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 44.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[11]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 45.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[11]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 45.221 6.529 0 simundump kreac /kinetics/chain/kinetics[11]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 46.221 9.529 0 simundump kpool /kinetics/chain/kinetics[11]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 46.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[11]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 47.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[11]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 48.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[11]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 49.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[11]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 44.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[11]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 47.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[11]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 48.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[11]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 41.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[11]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 42.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[11]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 45 11 0 simundump kreac /kinetics/chain/kinetics[11]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 46 14 0 simundump kpool /kinetics/chain/kinetics[11]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 52 -3 0 simundump kpool /kinetics/chain/kinetics[11]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 48 9 0 simundump kenz /kinetics/chain/kinetics[11]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 54 10 0 simundump kenz /kinetics/chain/kinetics[11]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 52 13 0 simundump kenz /kinetics/chain/kinetics[11]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 57 20 0 simundump kpool /kinetics/chain/kinetics[11]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 61 1 \ 0 simundump kenz /kinetics/chain/kinetics[11]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 58 \ 10 0 simundump kreac /kinetics/chain/kinetics[11]/MAPK*/diff 0 0.101 0.001 "" \ white black 62 4 0 simundump group /kinetics/chain/kinetics[11]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 63 11 0 simundump kpool /kinetics/chain/kinetics[11]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 54 8 0 simundump kreac /kinetics/chain/kinetics[11]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 55 11 0 simundump kpool /kinetics/chain/kinetics[11]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 57 8 0 simundump kreac /kinetics/chain/kinetics[11]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 58 11 0 simundump kpool /kinetics/chain/kinetics[11]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 54 4 0 simundump kreac /kinetics/chain/kinetics[11]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 55 7 0 simundump kpool /kinetics/chain/kinetics[11]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 54 1 0 simundump kreac /kinetics/chain/kinetics[11]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 55 4 0 simundump kpool /kinetics/chain/kinetics[11]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 60 8 0 simundump kreac /kinetics/chain/kinetics[11]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 61 11 0 simundump kpool /kinetics/chain/kinetics[11]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 57 1 0 simundump kreac /kinetics/chain/kinetics[11]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 58 4 0 simundump kpool /kinetics/chain/kinetics[11]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 61 4 0 simundump kenz /kinetics/chain/kinetics[11]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 56 3 0 simundump kenz /kinetics/chain/kinetics[11]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 61 3 \ 0 simundump kreac /kinetics/chain/kinetics[11]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 62 7 0 simundump kpool /kinetics/chain/kinetics[11]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 57 4 0 simundump kreac /kinetics/chain/kinetics[11]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 58 7 0 simundump kpool /kinetics/chain/kinetics[11]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 53 6 0 simundump kenz /kinetics/chain/kinetics[11]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 56 6 0 simundump kenz /kinetics/chain/kinetics[11]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 59 6 0 simundump kreac /kinetics/chain/kinetics[11]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 54 9 0 simundump kpool /kinetics/chain/kinetics[11]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 53 5 0 simundump kenz /kinetics/chain/kinetics[11]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 56 \ 5 0 simundump kenz /kinetics/chain/kinetics[11]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 59 5 0 simundump kreac /kinetics/chain/kinetics[11]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 54 8 0 simundump kpool /kinetics/chain/kinetics[11]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 53 2 0 simundump kenz /kinetics/chain/kinetics[11]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 54 3 0 simundump kenz /kinetics/chain/kinetics[11]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 59 \ 3 0 simundump kreac /kinetics/chain/kinetics[11]/MKP-1/diff 0 0.101 0.001 "" \ white black 54 5 0 simundump kreac /kinetics/chain/kinetics[11]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 51 9 0 simundump kpool /kinetics/chain/kinetics[11]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 57 9 0 simundump kenz /kinetics/chain/kinetics[11]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 56 10 0 simundump kenz /kinetics/chain/kinetics[11]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 59 7 0 simundump kenz /kinetics/chain/kinetics[11]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 56 7 0 simundump kenz /kinetics/chain/kinetics[11]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 60 10 0 simundump kreac /kinetics/chain/kinetics[11]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 58 12 0 simundump group /kinetics/chain/kinetics[11]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 62.513 16.351 0 simundump kreac /kinetics/chain/kinetics[11]/Ras/dephosph-GEF 1 1 0 "" white \ blue 57.07 17.881 0 simundump kpool /kinetics/chain/kinetics[11]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 60.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[11]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 60 17 0 simundump kreac /kinetics/chain/kinetics[11]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 61.453 21.352 0 simundump kpool /kinetics/chain/kinetics[11]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 54.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[11]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 55.085 16.086 0 simundump kreac /kinetics/chain/kinetics[11]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 55.448 20.246 0 simundump kpool /kinetics/chain/kinetics[11]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 60.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[11]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 61.564 16.084 0 simundump kpool /kinetics/chain/kinetics[11]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 54.131 14.165 0 simundump kreac /kinetics/chain/kinetics[11]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 55.131 17.165 0 simundump kreac /kinetics/chain/kinetics[11]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 57.098 13.5 0 simundump kreac /kinetics/chain/kinetics[11]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 52.023 15.524 0 simundump kpool /kinetics/chain/kinetics[11]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 49.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[11]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 50.35 17.349 0 simundump kpool /kinetics/chain/kinetics[11]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 54.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[11]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 57.012 12.403 0 simundump kreac /kinetics/chain/kinetics[11]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 55.655 15.338 0 simundump kreac /kinetics/chain/kinetics[11]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 50.486 21.679 0 simundump kpool /kinetics/chain/kinetics[11]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 53.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[11]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 53.022 18.657 0 simundump kreac /kinetics/chain/kinetics[11]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 54.345 22.58 0 simundump group /kinetics/chain/kinetics[11]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 38 21 0 simundump kpool /kinetics/chain/kinetics[11]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 35 30 0 simundump kreac /kinetics/chain/kinetics[11]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 36 33 0 simundump kreac /kinetics/chain/kinetics[11]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 37.6 23.26 0 simundump kpool /kinetics/chain/kinetics[11]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 41.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[11]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 42.489 27.397 0 simundump kpool /kinetics/chain/kinetics[11]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 46 24 0 simundump kreac /kinetics/chain/kinetics[11]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 47 27 0 simundump kreac /kinetics/chain/kinetics[11]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 38 30 0 simundump kpool /kinetics/chain/kinetics[11]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 42.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[11]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 43.999 30.258 0 simundump kreac /kinetics/chain/kinetics[11]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 39.158 26.225 0 simundump kreac /kinetics/chain/kinetics[11]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 44 30 0 simundump kpool /kinetics/chain/kinetics[11]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 41 31 0 simundump kreac /kinetics/chain/kinetics[11]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 42 34 0 simundump kpool /kinetics/chain/kinetics[11]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 30 23 0 simundump kreac /kinetics/chain/kinetics[11]/Ca/diff 0 0.101 0.001 "" white \ black 31 26 0 simundump kreac /kinetics/chain/kinetics[11]/Ras-act-unphosph-raf 0 0 0 "" \ white black 52 8 0 simundump group /kinetics/chain/kinetics[11]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 41 19 0 simundump kpool /kinetics/chain/kinetics[11]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 37 17 0 simundump kreac /kinetics/chain/kinetics[11]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 38 20 0 simundump kpool /kinetics/chain/kinetics[11]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 37 9 0 simundump kenz /kinetics/chain/kinetics[11]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 38 10 0 simundump kreac /kinetics/chain/kinetics[11]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 38 12 0 simundump kpool /kinetics/chain/kinetics[11]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 41 12 0 simundump kreac /kinetics/chain/kinetics[11]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 40 7 0 simundump kpool /kinetics/chain/kinetics[11]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 36 5 0 simundump kpool /kinetics/chain/kinetics[11]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 36 \ 14 0 simundump kenz /kinetics/chain/kinetics[11]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 36 13 0 simundump kreac /kinetics/chain/kinetics[11]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 37 17 0 simundump kpool /kinetics/chain/kinetics[11]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 33 12 0 simundump kreac /kinetics/chain/kinetics[11]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 34 15 0 simundump kreac /kinetics/chain/kinetics[11]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 31 9 0 simundump kreac /kinetics/chain/kinetics[11]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 31 16 0 simundump kpool /kinetics/chain/kinetics[11]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 30 30 0 simundump kreac /kinetics/chain/kinetics[11]/Ca_diff 0 5 5 "" white black 30 \ 26 0 simundump group /kinetics/chain/kinetics[12] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 52 0 0 simundump group /kinetics/chain/kinetics[12]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 48.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[12]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 47.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[12]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 48.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[12]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 47.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[12]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 49.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[12]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 48.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[12]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 49.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[12]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 49.221 6.529 0 simundump kreac /kinetics/chain/kinetics[12]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 50.221 9.529 0 simundump kpool /kinetics/chain/kinetics[12]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 50.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[12]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 51.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[12]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 52.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[12]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 53.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[12]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 48.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[12]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 51.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[12]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 52.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[12]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 45.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[12]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 46.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[12]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 49 11 0 simundump kreac /kinetics/chain/kinetics[12]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 50 14 0 simundump kpool /kinetics/chain/kinetics[12]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 56 -3 0 simundump kpool /kinetics/chain/kinetics[12]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 52 9 0 simundump kenz /kinetics/chain/kinetics[12]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 58 10 0 simundump kenz /kinetics/chain/kinetics[12]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 56 13 0 simundump kenz /kinetics/chain/kinetics[12]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 61 20 0 simundump kpool /kinetics/chain/kinetics[12]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 65 1 \ 0 simundump kenz /kinetics/chain/kinetics[12]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 62 \ 10 0 simundump kreac /kinetics/chain/kinetics[12]/MAPK*/diff 0 0.101 0.001 "" \ white black 66 4 0 simundump group /kinetics/chain/kinetics[12]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 67 11 0 simundump kpool /kinetics/chain/kinetics[12]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 58 8 0 simundump kreac /kinetics/chain/kinetics[12]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 59 11 0 simundump kpool /kinetics/chain/kinetics[12]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 61 8 0 simundump kreac /kinetics/chain/kinetics[12]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 62 11 0 simundump kpool /kinetics/chain/kinetics[12]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 58 4 0 simundump kreac /kinetics/chain/kinetics[12]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 59 7 0 simundump kpool /kinetics/chain/kinetics[12]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 58 1 0 simundump kreac /kinetics/chain/kinetics[12]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 59 4 0 simundump kpool /kinetics/chain/kinetics[12]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 64 8 0 simundump kreac /kinetics/chain/kinetics[12]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 65 11 0 simundump kpool /kinetics/chain/kinetics[12]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 61 1 0 simundump kreac /kinetics/chain/kinetics[12]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 62 4 0 simundump kpool /kinetics/chain/kinetics[12]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 65 4 0 simundump kenz /kinetics/chain/kinetics[12]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 60 3 0 simundump kenz /kinetics/chain/kinetics[12]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 65 3 \ 0 simundump kreac /kinetics/chain/kinetics[12]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 66 7 0 simundump kpool /kinetics/chain/kinetics[12]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 61 4 0 simundump kreac /kinetics/chain/kinetics[12]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 62 7 0 simundump kpool /kinetics/chain/kinetics[12]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 57 6 0 simundump kenz /kinetics/chain/kinetics[12]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 60 6 0 simundump kenz /kinetics/chain/kinetics[12]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 63 6 0 simundump kreac /kinetics/chain/kinetics[12]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 58 9 0 simundump kpool /kinetics/chain/kinetics[12]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 57 5 0 simundump kenz /kinetics/chain/kinetics[12]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 60 \ 5 0 simundump kenz /kinetics/chain/kinetics[12]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 63 5 0 simundump kreac /kinetics/chain/kinetics[12]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 58 8 0 simundump kpool /kinetics/chain/kinetics[12]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 57 2 0 simundump kenz /kinetics/chain/kinetics[12]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 58 3 0 simundump kenz /kinetics/chain/kinetics[12]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 63 \ 3 0 simundump kreac /kinetics/chain/kinetics[12]/MKP-1/diff 0 0.101 0.001 "" \ white black 58 5 0 simundump kreac /kinetics/chain/kinetics[12]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 55 9 0 simundump kpool /kinetics/chain/kinetics[12]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 61 9 0 simundump kenz /kinetics/chain/kinetics[12]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 60 10 0 simundump kenz /kinetics/chain/kinetics[12]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 63 7 0 simundump kenz /kinetics/chain/kinetics[12]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 60 7 0 simundump kenz /kinetics/chain/kinetics[12]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 64 10 0 simundump kreac /kinetics/chain/kinetics[12]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 62 12 0 simundump group /kinetics/chain/kinetics[12]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 66.513 16.351 0 simundump kreac /kinetics/chain/kinetics[12]/Ras/dephosph-GEF 1 1 0 "" white \ blue 61.07 17.881 0 simundump kpool /kinetics/chain/kinetics[12]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 64.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[12]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 64 17 0 simundump kreac /kinetics/chain/kinetics[12]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 65.453 21.352 0 simundump kpool /kinetics/chain/kinetics[12]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 58.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[12]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 59.085 16.086 0 simundump kreac /kinetics/chain/kinetics[12]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 59.448 20.246 0 simundump kpool /kinetics/chain/kinetics[12]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 64.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[12]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 65.564 16.084 0 simundump kpool /kinetics/chain/kinetics[12]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 58.131 14.165 0 simundump kreac /kinetics/chain/kinetics[12]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 59.131 17.165 0 simundump kreac /kinetics/chain/kinetics[12]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 61.098 13.5 0 simundump kreac /kinetics/chain/kinetics[12]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 56.023 15.524 0 simundump kpool /kinetics/chain/kinetics[12]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 53.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[12]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 54.35 17.349 0 simundump kpool /kinetics/chain/kinetics[12]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 58.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[12]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 61.012 12.403 0 simundump kreac /kinetics/chain/kinetics[12]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 59.655 15.338 0 simundump kreac /kinetics/chain/kinetics[12]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 54.486 21.679 0 simundump kpool /kinetics/chain/kinetics[12]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 57.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[12]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 57.022 18.657 0 simundump kreac /kinetics/chain/kinetics[12]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 58.345 22.58 0 simundump group /kinetics/chain/kinetics[12]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 42 21 0 simundump kpool /kinetics/chain/kinetics[12]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 39 30 0 simundump kreac /kinetics/chain/kinetics[12]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 40 33 0 simundump kreac /kinetics/chain/kinetics[12]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 41.6 23.26 0 simundump kpool /kinetics/chain/kinetics[12]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 45.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[12]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 46.489 27.397 0 simundump kpool /kinetics/chain/kinetics[12]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 50 24 0 simundump kreac /kinetics/chain/kinetics[12]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 51 27 0 simundump kreac /kinetics/chain/kinetics[12]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 42 30 0 simundump kpool /kinetics/chain/kinetics[12]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 46.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[12]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 47.999 30.258 0 simundump kreac /kinetics/chain/kinetics[12]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 43.158 26.225 0 simundump kreac /kinetics/chain/kinetics[12]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 48 30 0 simundump kpool /kinetics/chain/kinetics[12]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 45 31 0 simundump kreac /kinetics/chain/kinetics[12]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 46 34 0 simundump kpool /kinetics/chain/kinetics[12]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 34 23 0 simundump kreac /kinetics/chain/kinetics[12]/Ca/diff 0 0.101 0.001 "" white \ black 35 26 0 simundump kreac /kinetics/chain/kinetics[12]/Ras-act-unphosph-raf 0 0 0 "" \ white black 56 8 0 simundump group /kinetics/chain/kinetics[12]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 45 19 0 simundump kpool /kinetics/chain/kinetics[12]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 41 17 0 simundump kreac /kinetics/chain/kinetics[12]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 42 20 0 simundump kpool /kinetics/chain/kinetics[12]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 41 9 0 simundump kenz /kinetics/chain/kinetics[12]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 42 10 0 simundump kreac /kinetics/chain/kinetics[12]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 42 12 0 simundump kpool /kinetics/chain/kinetics[12]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 45 12 0 simundump kreac /kinetics/chain/kinetics[12]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 44 7 0 simundump kpool /kinetics/chain/kinetics[12]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 40 5 0 simundump kpool /kinetics/chain/kinetics[12]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 40 \ 14 0 simundump kenz /kinetics/chain/kinetics[12]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 40 13 0 simundump kreac /kinetics/chain/kinetics[12]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 41 17 0 simundump kpool /kinetics/chain/kinetics[12]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 37 12 0 simundump kreac /kinetics/chain/kinetics[12]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 38 15 0 simundump kreac /kinetics/chain/kinetics[12]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 35 9 0 simundump kreac /kinetics/chain/kinetics[12]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 35 16 0 simundump kpool /kinetics/chain/kinetics[12]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 34 30 0 simundump kreac /kinetics/chain/kinetics[12]/Ca_diff 0 5 5 "" white black 34 \ 26 0 simundump group /kinetics/chain/kinetics[13] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 56 0 0 simundump group /kinetics/chain/kinetics[13]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 52.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[13]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 51.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[13]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 52.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[13]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 51.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[13]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 53.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[13]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 52.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[13]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 53.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[13]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 53.221 6.529 0 simundump kreac /kinetics/chain/kinetics[13]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 54.221 9.529 0 simundump kpool /kinetics/chain/kinetics[13]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 54.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[13]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 55.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[13]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 56.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[13]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 57.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[13]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 52.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[13]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 55.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[13]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 56.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[13]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 49.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[13]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 50.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[13]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 53 11 0 simundump kreac /kinetics/chain/kinetics[13]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 54 14 0 simundump kpool /kinetics/chain/kinetics[13]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 60 -3 0 simundump kpool /kinetics/chain/kinetics[13]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 56 9 0 simundump kenz /kinetics/chain/kinetics[13]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 62 10 0 simundump kenz /kinetics/chain/kinetics[13]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 60 13 0 simundump kenz /kinetics/chain/kinetics[13]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 65 20 0 simundump kpool /kinetics/chain/kinetics[13]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 69 1 \ 0 simundump kenz /kinetics/chain/kinetics[13]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 66 \ 10 0 simundump kreac /kinetics/chain/kinetics[13]/MAPK*/diff 0 0.101 0.001 "" \ white black 70 4 0 simundump group /kinetics/chain/kinetics[13]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 71 11 0 simundump kpool /kinetics/chain/kinetics[13]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 62 8 0 simundump kreac /kinetics/chain/kinetics[13]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 63 11 0 simundump kpool /kinetics/chain/kinetics[13]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 65 8 0 simundump kreac /kinetics/chain/kinetics[13]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 66 11 0 simundump kpool /kinetics/chain/kinetics[13]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 62 4 0 simundump kreac /kinetics/chain/kinetics[13]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 63 7 0 simundump kpool /kinetics/chain/kinetics[13]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 62 1 0 simundump kreac /kinetics/chain/kinetics[13]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 63 4 0 simundump kpool /kinetics/chain/kinetics[13]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 68 8 0 simundump kreac /kinetics/chain/kinetics[13]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 69 11 0 simundump kpool /kinetics/chain/kinetics[13]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 65 1 0 simundump kreac /kinetics/chain/kinetics[13]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 66 4 0 simundump kpool /kinetics/chain/kinetics[13]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 69 4 0 simundump kenz /kinetics/chain/kinetics[13]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 64 3 0 simundump kenz /kinetics/chain/kinetics[13]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 69 3 \ 0 simundump kreac /kinetics/chain/kinetics[13]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 70 7 0 simundump kpool /kinetics/chain/kinetics[13]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 65 4 0 simundump kreac /kinetics/chain/kinetics[13]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 66 7 0 simundump kpool /kinetics/chain/kinetics[13]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 61 6 0 simundump kenz /kinetics/chain/kinetics[13]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 64 6 0 simundump kenz /kinetics/chain/kinetics[13]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 67 6 0 simundump kreac /kinetics/chain/kinetics[13]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 62 9 0 simundump kpool /kinetics/chain/kinetics[13]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 61 5 0 simundump kenz /kinetics/chain/kinetics[13]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 64 \ 5 0 simundump kenz /kinetics/chain/kinetics[13]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 67 5 0 simundump kreac /kinetics/chain/kinetics[13]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 62 8 0 simundump kpool /kinetics/chain/kinetics[13]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 61 2 0 simundump kenz /kinetics/chain/kinetics[13]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 62 3 0 simundump kenz /kinetics/chain/kinetics[13]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 67 \ 3 0 simundump kreac /kinetics/chain/kinetics[13]/MKP-1/diff 0 0.101 0.001 "" \ white black 62 5 0 simundump kreac /kinetics/chain/kinetics[13]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 59 9 0 simundump kpool /kinetics/chain/kinetics[13]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 65 9 0 simundump kenz /kinetics/chain/kinetics[13]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 64 10 0 simundump kenz /kinetics/chain/kinetics[13]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 67 7 0 simundump kenz /kinetics/chain/kinetics[13]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 64 7 0 simundump kenz /kinetics/chain/kinetics[13]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 68 10 0 simundump kreac /kinetics/chain/kinetics[13]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 66 12 0 simundump group /kinetics/chain/kinetics[13]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 70.513 16.351 0 simundump kreac /kinetics/chain/kinetics[13]/Ras/dephosph-GEF 1 1 0 "" white \ blue 65.07 17.881 0 simundump kpool /kinetics/chain/kinetics[13]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 68.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[13]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 68 17 0 simundump kreac /kinetics/chain/kinetics[13]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 69.453 21.352 0 simundump kpool /kinetics/chain/kinetics[13]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 62.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[13]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 63.085 16.086 0 simundump kreac /kinetics/chain/kinetics[13]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 63.448 20.246 0 simundump kpool /kinetics/chain/kinetics[13]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 68.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[13]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 69.564 16.084 0 simundump kpool /kinetics/chain/kinetics[13]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 62.131 14.165 0 simundump kreac /kinetics/chain/kinetics[13]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 63.131 17.165 0 simundump kreac /kinetics/chain/kinetics[13]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 65.098 13.5 0 simundump kreac /kinetics/chain/kinetics[13]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 60.023 15.524 0 simundump kpool /kinetics/chain/kinetics[13]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 57.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[13]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 58.35 17.349 0 simundump kpool /kinetics/chain/kinetics[13]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 62.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[13]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 65.012 12.403 0 simundump kreac /kinetics/chain/kinetics[13]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 63.655 15.338 0 simundump kreac /kinetics/chain/kinetics[13]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 58.486 21.679 0 simundump kpool /kinetics/chain/kinetics[13]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 61.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[13]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 61.022 18.657 0 simundump kreac /kinetics/chain/kinetics[13]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 62.345 22.58 0 simundump group /kinetics/chain/kinetics[13]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 46 21 0 simundump kpool /kinetics/chain/kinetics[13]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 43 30 0 simundump kreac /kinetics/chain/kinetics[13]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 44 33 0 simundump kreac /kinetics/chain/kinetics[13]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 45.6 23.26 0 simundump kpool /kinetics/chain/kinetics[13]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 49.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[13]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 50.489 27.397 0 simundump kpool /kinetics/chain/kinetics[13]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 54 24 0 simundump kreac /kinetics/chain/kinetics[13]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 55 27 0 simundump kreac /kinetics/chain/kinetics[13]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 46 30 0 simundump kpool /kinetics/chain/kinetics[13]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 50.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[13]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 51.999 30.258 0 simundump kreac /kinetics/chain/kinetics[13]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 47.158 26.225 0 simundump kreac /kinetics/chain/kinetics[13]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 52 30 0 simundump kpool /kinetics/chain/kinetics[13]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 49 31 0 simundump kreac /kinetics/chain/kinetics[13]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 50 34 0 simundump kpool /kinetics/chain/kinetics[13]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 38 23 0 simundump kreac /kinetics/chain/kinetics[13]/Ca/diff 0 0.101 0.001 "" white \ black 39 26 0 simundump kreac /kinetics/chain/kinetics[13]/Ras-act-unphosph-raf 0 0 0 "" \ white black 60 8 0 simundump group /kinetics/chain/kinetics[13]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 49 19 0 simundump kpool /kinetics/chain/kinetics[13]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 45 17 0 simundump kreac /kinetics/chain/kinetics[13]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 46 20 0 simundump kpool /kinetics/chain/kinetics[13]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 45 9 0 simundump kenz /kinetics/chain/kinetics[13]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 46 10 0 simundump kreac /kinetics/chain/kinetics[13]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 46 12 0 simundump kpool /kinetics/chain/kinetics[13]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 49 12 0 simundump kreac /kinetics/chain/kinetics[13]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 48 7 0 simundump kpool /kinetics/chain/kinetics[13]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 44 5 0 simundump kpool /kinetics/chain/kinetics[13]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 44 \ 14 0 simundump kenz /kinetics/chain/kinetics[13]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 44 13 0 simundump kreac /kinetics/chain/kinetics[13]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 45 17 0 simundump kpool /kinetics/chain/kinetics[13]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 41 12 0 simundump kreac /kinetics/chain/kinetics[13]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 42 15 0 simundump kreac /kinetics/chain/kinetics[13]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 39 9 0 simundump kreac /kinetics/chain/kinetics[13]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 39 16 0 simundump kpool /kinetics/chain/kinetics[13]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 38 30 0 simundump kreac /kinetics/chain/kinetics[13]/Ca_diff 0 5 5 "" white black 38 \ 26 0 simundump group /kinetics/chain/kinetics[14] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 60 0 0 simundump group /kinetics/chain/kinetics[14]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 56.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[14]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 55.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[14]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 56.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[14]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 55.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[14]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 57.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[14]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 56.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[14]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 57.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[14]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 57.221 6.529 0 simundump kreac /kinetics/chain/kinetics[14]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 58.221 9.529 0 simundump kpool /kinetics/chain/kinetics[14]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 58.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[14]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 59.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[14]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 60.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[14]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 61.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[14]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 56.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[14]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 59.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[14]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 60.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[14]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 53.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[14]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 54.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[14]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 57 11 0 simundump kreac /kinetics/chain/kinetics[14]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 58 14 0 simundump kpool /kinetics/chain/kinetics[14]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 64 -3 0 simundump kpool /kinetics/chain/kinetics[14]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 60 9 0 simundump kenz /kinetics/chain/kinetics[14]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 66 10 0 simundump kenz /kinetics/chain/kinetics[14]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 64 13 0 simundump kenz /kinetics/chain/kinetics[14]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 69 20 0 simundump kpool /kinetics/chain/kinetics[14]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 73 1 \ 0 simundump kenz /kinetics/chain/kinetics[14]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 70 \ 10 0 simundump kreac /kinetics/chain/kinetics[14]/MAPK*/diff 0 0.101 0.001 "" \ white black 74 4 0 simundump group /kinetics/chain/kinetics[14]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 75 11 0 simundump kpool /kinetics/chain/kinetics[14]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 66 8 0 simundump kreac /kinetics/chain/kinetics[14]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 67 11 0 simundump kpool /kinetics/chain/kinetics[14]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 69 8 0 simundump kreac /kinetics/chain/kinetics[14]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 70 11 0 simundump kpool /kinetics/chain/kinetics[14]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 66 4 0 simundump kreac /kinetics/chain/kinetics[14]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 67 7 0 simundump kpool /kinetics/chain/kinetics[14]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 66 1 0 simundump kreac /kinetics/chain/kinetics[14]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 67 4 0 simundump kpool /kinetics/chain/kinetics[14]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 72 8 0 simundump kreac /kinetics/chain/kinetics[14]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 73 11 0 simundump kpool /kinetics/chain/kinetics[14]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 69 1 0 simundump kreac /kinetics/chain/kinetics[14]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 70 4 0 simundump kpool /kinetics/chain/kinetics[14]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 73 4 0 simundump kenz /kinetics/chain/kinetics[14]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 68 3 0 simundump kenz /kinetics/chain/kinetics[14]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 73 3 \ 0 simundump kreac /kinetics/chain/kinetics[14]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 74 7 0 simundump kpool /kinetics/chain/kinetics[14]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 69 4 0 simundump kreac /kinetics/chain/kinetics[14]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 70 7 0 simundump kpool /kinetics/chain/kinetics[14]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 65 6 0 simundump kenz /kinetics/chain/kinetics[14]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 68 6 0 simundump kenz /kinetics/chain/kinetics[14]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 71 6 0 simundump kreac /kinetics/chain/kinetics[14]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 66 9 0 simundump kpool /kinetics/chain/kinetics[14]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 65 5 0 simundump kenz /kinetics/chain/kinetics[14]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 68 \ 5 0 simundump kenz /kinetics/chain/kinetics[14]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 71 5 0 simundump kreac /kinetics/chain/kinetics[14]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 66 8 0 simundump kpool /kinetics/chain/kinetics[14]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 65 2 0 simundump kenz /kinetics/chain/kinetics[14]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 66 3 0 simundump kenz /kinetics/chain/kinetics[14]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 71 \ 3 0 simundump kreac /kinetics/chain/kinetics[14]/MKP-1/diff 0 0.101 0.001 "" \ white black 66 5 0 simundump kreac /kinetics/chain/kinetics[14]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 63 9 0 simundump kpool /kinetics/chain/kinetics[14]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 69 9 0 simundump kenz /kinetics/chain/kinetics[14]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 68 10 0 simundump kenz /kinetics/chain/kinetics[14]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 71 7 0 simundump kenz /kinetics/chain/kinetics[14]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 68 7 0 simundump kenz /kinetics/chain/kinetics[14]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 72 10 0 simundump kreac /kinetics/chain/kinetics[14]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 70 12 0 simundump group /kinetics/chain/kinetics[14]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 74.513 16.351 0 simundump kreac /kinetics/chain/kinetics[14]/Ras/dephosph-GEF 1 1 0 "" white \ blue 69.07 17.881 0 simundump kpool /kinetics/chain/kinetics[14]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 72.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[14]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 72 17 0 simundump kreac /kinetics/chain/kinetics[14]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 73.453 21.352 0 simundump kpool /kinetics/chain/kinetics[14]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 66.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[14]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 67.085 16.086 0 simundump kreac /kinetics/chain/kinetics[14]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 67.448 20.246 0 simundump kpool /kinetics/chain/kinetics[14]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 72.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[14]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 73.564 16.084 0 simundump kpool /kinetics/chain/kinetics[14]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 66.131 14.165 0 simundump kreac /kinetics/chain/kinetics[14]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 67.131 17.165 0 simundump kreac /kinetics/chain/kinetics[14]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 69.098 13.5 0 simundump kreac /kinetics/chain/kinetics[14]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 64.023 15.524 0 simundump kpool /kinetics/chain/kinetics[14]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 61.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[14]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 62.35 17.349 0 simundump kpool /kinetics/chain/kinetics[14]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 66.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[14]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 69.012 12.403 0 simundump kreac /kinetics/chain/kinetics[14]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 67.655 15.338 0 simundump kreac /kinetics/chain/kinetics[14]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 62.486 21.679 0 simundump kpool /kinetics/chain/kinetics[14]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 65.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[14]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 65.022 18.657 0 simundump kreac /kinetics/chain/kinetics[14]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 66.345 22.58 0 simundump group /kinetics/chain/kinetics[14]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 50 21 0 simundump kpool /kinetics/chain/kinetics[14]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 47 30 0 simundump kreac /kinetics/chain/kinetics[14]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 48 33 0 simundump kreac /kinetics/chain/kinetics[14]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 49.6 23.26 0 simundump kpool /kinetics/chain/kinetics[14]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 53.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[14]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 54.489 27.397 0 simundump kpool /kinetics/chain/kinetics[14]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 58 24 0 simundump kreac /kinetics/chain/kinetics[14]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 59 27 0 simundump kreac /kinetics/chain/kinetics[14]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 50 30 0 simundump kpool /kinetics/chain/kinetics[14]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 54.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[14]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 55.999 30.258 0 simundump kreac /kinetics/chain/kinetics[14]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 51.158 26.225 0 simundump kreac /kinetics/chain/kinetics[14]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 56 30 0 simundump kpool /kinetics/chain/kinetics[14]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 53 31 0 simundump kreac /kinetics/chain/kinetics[14]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 54 34 0 simundump kpool /kinetics/chain/kinetics[14]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 42 23 0 simundump kreac /kinetics/chain/kinetics[14]/Ca/diff 0 0.101 0.001 "" white \ black 43 26 0 simundump kreac /kinetics/chain/kinetics[14]/Ras-act-unphosph-raf 0 0 0 "" \ white black 64 8 0 simundump group /kinetics/chain/kinetics[14]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 53 19 0 simundump kpool /kinetics/chain/kinetics[14]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 49 17 0 simundump kreac /kinetics/chain/kinetics[14]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 50 20 0 simundump kpool /kinetics/chain/kinetics[14]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 49 9 0 simundump kenz /kinetics/chain/kinetics[14]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 50 10 0 simundump kreac /kinetics/chain/kinetics[14]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 50 12 0 simundump kpool /kinetics/chain/kinetics[14]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 53 12 0 simundump kreac /kinetics/chain/kinetics[14]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 52 7 0 simundump kpool /kinetics/chain/kinetics[14]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 48 5 0 simundump kpool /kinetics/chain/kinetics[14]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 48 \ 14 0 simundump kenz /kinetics/chain/kinetics[14]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 48 13 0 simundump kreac /kinetics/chain/kinetics[14]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 49 17 0 simundump kpool /kinetics/chain/kinetics[14]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 45 12 0 simundump kreac /kinetics/chain/kinetics[14]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 46 15 0 simundump kreac /kinetics/chain/kinetics[14]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 43 9 0 simundump kreac /kinetics/chain/kinetics[14]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 43 16 0 simundump kpool /kinetics/chain/kinetics[14]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 42 30 0 simundump kreac /kinetics/chain/kinetics[14]/Ca_diff 0 5 5 "" white black 42 \ 26 0 simundump group /kinetics/chain/kinetics[15] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 64 0 0 simundump group /kinetics/chain/kinetics[15]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 60.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[15]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 59.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[15]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 60.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[15]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 59.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[15]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 61.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[15]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 60.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[15]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 61.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[15]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 61.221 6.529 0 simundump kreac /kinetics/chain/kinetics[15]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 62.221 9.529 0 simundump kpool /kinetics/chain/kinetics[15]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 62.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[15]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 63.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[15]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 64.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[15]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 65.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[15]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 60.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[15]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 63.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[15]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 64.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[15]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 57.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[15]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 58.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[15]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 61 11 0 simundump kreac /kinetics/chain/kinetics[15]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 62 14 0 simundump kpool /kinetics/chain/kinetics[15]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 68 -3 0 simundump kpool /kinetics/chain/kinetics[15]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 64 9 0 simundump kenz /kinetics/chain/kinetics[15]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 70 10 0 simundump kenz /kinetics/chain/kinetics[15]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 68 13 0 simundump kenz /kinetics/chain/kinetics[15]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 73 20 0 simundump kpool /kinetics/chain/kinetics[15]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 77 1 \ 0 simundump kenz /kinetics/chain/kinetics[15]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 74 \ 10 0 simundump kreac /kinetics/chain/kinetics[15]/MAPK*/diff 0 0.101 0.001 "" \ white black 78 4 0 simundump group /kinetics/chain/kinetics[15]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 79 11 0 simundump kpool /kinetics/chain/kinetics[15]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 70 8 0 simundump kreac /kinetics/chain/kinetics[15]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 71 11 0 simundump kpool /kinetics/chain/kinetics[15]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 73 8 0 simundump kreac /kinetics/chain/kinetics[15]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 74 11 0 simundump kpool /kinetics/chain/kinetics[15]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 70 4 0 simundump kreac /kinetics/chain/kinetics[15]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 71 7 0 simundump kpool /kinetics/chain/kinetics[15]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 70 1 0 simundump kreac /kinetics/chain/kinetics[15]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 71 4 0 simundump kpool /kinetics/chain/kinetics[15]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 76 8 0 simundump kreac /kinetics/chain/kinetics[15]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 77 11 0 simundump kpool /kinetics/chain/kinetics[15]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 73 1 0 simundump kreac /kinetics/chain/kinetics[15]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 74 4 0 simundump kpool /kinetics/chain/kinetics[15]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 77 4 0 simundump kenz /kinetics/chain/kinetics[15]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 72 3 0 simundump kenz /kinetics/chain/kinetics[15]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 77 3 \ 0 simundump kreac /kinetics/chain/kinetics[15]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 78 7 0 simundump kpool /kinetics/chain/kinetics[15]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 73 4 0 simundump kreac /kinetics/chain/kinetics[15]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 74 7 0 simundump kpool /kinetics/chain/kinetics[15]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 69 6 0 simundump kenz /kinetics/chain/kinetics[15]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 72 6 0 simundump kenz /kinetics/chain/kinetics[15]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 75 6 0 simundump kreac /kinetics/chain/kinetics[15]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 70 9 0 simundump kpool /kinetics/chain/kinetics[15]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 69 5 0 simundump kenz /kinetics/chain/kinetics[15]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 72 \ 5 0 simundump kenz /kinetics/chain/kinetics[15]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 75 5 0 simundump kreac /kinetics/chain/kinetics[15]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 70 8 0 simundump kpool /kinetics/chain/kinetics[15]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 69 2 0 simundump kenz /kinetics/chain/kinetics[15]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 70 3 0 simundump kenz /kinetics/chain/kinetics[15]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 75 \ 3 0 simundump kreac /kinetics/chain/kinetics[15]/MKP-1/diff 0 0.101 0.001 "" \ white black 70 5 0 simundump kreac /kinetics/chain/kinetics[15]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 67 9 0 simundump kpool /kinetics/chain/kinetics[15]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 73 9 0 simundump kenz /kinetics/chain/kinetics[15]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 72 10 0 simundump kenz /kinetics/chain/kinetics[15]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 75 7 0 simundump kenz /kinetics/chain/kinetics[15]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 72 7 0 simundump kenz /kinetics/chain/kinetics[15]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 76 10 0 simundump kreac /kinetics/chain/kinetics[15]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 74 12 0 simundump group /kinetics/chain/kinetics[15]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 78.513 16.351 0 simundump kreac /kinetics/chain/kinetics[15]/Ras/dephosph-GEF 1 1 0 "" white \ blue 73.07 17.881 0 simundump kpool /kinetics/chain/kinetics[15]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 76.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[15]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 76 17 0 simundump kreac /kinetics/chain/kinetics[15]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 77.453 21.352 0 simundump kpool /kinetics/chain/kinetics[15]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 70.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[15]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 71.086 16.086 0 simundump kreac /kinetics/chain/kinetics[15]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 71.448 20.246 0 simundump kpool /kinetics/chain/kinetics[15]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 76.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[15]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 77.564 16.084 0 simundump kpool /kinetics/chain/kinetics[15]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 70.131 14.165 0 simundump kreac /kinetics/chain/kinetics[15]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 71.131 17.165 0 simundump kreac /kinetics/chain/kinetics[15]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 73.098 13.5 0 simundump kreac /kinetics/chain/kinetics[15]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 68.023 15.524 0 simundump kpool /kinetics/chain/kinetics[15]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 65.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[15]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 66.35 17.349 0 simundump kpool /kinetics/chain/kinetics[15]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 70.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[15]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 73.012 12.403 0 simundump kreac /kinetics/chain/kinetics[15]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 71.655 15.338 0 simundump kreac /kinetics/chain/kinetics[15]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 66.486 21.679 0 simundump kpool /kinetics/chain/kinetics[15]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 69.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[15]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 69.022 18.657 0 simundump kreac /kinetics/chain/kinetics[15]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 70.345 22.58 0 simundump group /kinetics/chain/kinetics[15]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 54 21 0 simundump kpool /kinetics/chain/kinetics[15]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 51 30 0 simundump kreac /kinetics/chain/kinetics[15]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 52 33 0 simundump kreac /kinetics/chain/kinetics[15]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 53.6 23.26 0 simundump kpool /kinetics/chain/kinetics[15]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 57.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[15]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 58.489 27.397 0 simundump kpool /kinetics/chain/kinetics[15]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 62 24 0 simundump kreac /kinetics/chain/kinetics[15]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 63 27 0 simundump kreac /kinetics/chain/kinetics[15]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 54 30 0 simundump kpool /kinetics/chain/kinetics[15]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 58.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[15]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 59.999 30.258 0 simundump kreac /kinetics/chain/kinetics[15]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 55.158 26.225 0 simundump kreac /kinetics/chain/kinetics[15]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 60 30 0 simundump kpool /kinetics/chain/kinetics[15]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 57 31 0 simundump kreac /kinetics/chain/kinetics[15]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 58 34 0 simundump kpool /kinetics/chain/kinetics[15]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 46 23 0 simundump kreac /kinetics/chain/kinetics[15]/Ca/diff 0 0.101 0.001 "" white \ black 47 26 0 simundump kreac /kinetics/chain/kinetics[15]/Ras-act-unphosph-raf 0 0 0 "" \ white black 68 8 0 simundump group /kinetics/chain/kinetics[15]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 57 19 0 simundump kpool /kinetics/chain/kinetics[15]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 53 17 0 simundump kreac /kinetics/chain/kinetics[15]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 54 20 0 simundump kpool /kinetics/chain/kinetics[15]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 53 9 0 simundump kenz /kinetics/chain/kinetics[15]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 54 10 0 simundump kreac /kinetics/chain/kinetics[15]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 54 12 0 simundump kpool /kinetics/chain/kinetics[15]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 57 12 0 simundump kreac /kinetics/chain/kinetics[15]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 56 7 0 simundump kpool /kinetics/chain/kinetics[15]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 52 5 0 simundump kpool /kinetics/chain/kinetics[15]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 52 \ 14 0 simundump kenz /kinetics/chain/kinetics[15]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 52 13 0 simundump kreac /kinetics/chain/kinetics[15]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 53 17 0 simundump kpool /kinetics/chain/kinetics[15]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 49 12 0 simundump kreac /kinetics/chain/kinetics[15]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 50 15 0 simundump kreac /kinetics/chain/kinetics[15]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 47 9 0 simundump kreac /kinetics/chain/kinetics[15]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 47 16 0 simundump kpool /kinetics/chain/kinetics[15]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 46 30 0 simundump kreac /kinetics/chain/kinetics[15]/Ca_diff 0 5 5 "" white black 46 \ 26 0 simundump group /kinetics/chain/kinetics[16] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 68 0 0 simundump group /kinetics/chain/kinetics[16]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 64.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[16]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 63.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[16]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 64.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[16]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 63.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[16]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 65.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[16]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 64.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[16]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 65.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[16]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 65.221 6.529 0 simundump kreac /kinetics/chain/kinetics[16]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 66.221 9.529 0 simundump kpool /kinetics/chain/kinetics[16]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 66.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[16]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 67.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[16]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 68.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[16]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 69.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[16]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 64.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[16]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 67.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[16]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 68.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[16]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 61.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[16]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 62.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[16]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 65 11 0 simundump kreac /kinetics/chain/kinetics[16]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 66 14 0 simundump kpool /kinetics/chain/kinetics[16]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 72 -3 0 simundump kpool /kinetics/chain/kinetics[16]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 68 9 0 simundump kenz /kinetics/chain/kinetics[16]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 74 10 0 simundump kenz /kinetics/chain/kinetics[16]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 72 13 0 simundump kenz /kinetics/chain/kinetics[16]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 77 20 0 simundump kpool /kinetics/chain/kinetics[16]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 81 1 \ 0 simundump kenz /kinetics/chain/kinetics[16]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 78 \ 10 0 simundump kreac /kinetics/chain/kinetics[16]/MAPK*/diff 0 0.101 0.001 "" \ white black 82 4 0 simundump group /kinetics/chain/kinetics[16]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 83 11 0 simundump kpool /kinetics/chain/kinetics[16]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 74 8 0 simundump kreac /kinetics/chain/kinetics[16]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 75 11 0 simundump kpool /kinetics/chain/kinetics[16]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 77 8 0 simundump kreac /kinetics/chain/kinetics[16]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 78 11 0 simundump kpool /kinetics/chain/kinetics[16]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 74 4 0 simundump kreac /kinetics/chain/kinetics[16]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 75 7 0 simundump kpool /kinetics/chain/kinetics[16]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 74 1 0 simundump kreac /kinetics/chain/kinetics[16]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 75 4 0 simundump kpool /kinetics/chain/kinetics[16]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 80 8 0 simundump kreac /kinetics/chain/kinetics[16]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 81 11 0 simundump kpool /kinetics/chain/kinetics[16]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 77 1 0 simundump kreac /kinetics/chain/kinetics[16]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 78 4 0 simundump kpool /kinetics/chain/kinetics[16]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 81 4 0 simundump kenz /kinetics/chain/kinetics[16]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 76 3 0 simundump kenz /kinetics/chain/kinetics[16]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 81 3 \ 0 simundump kreac /kinetics/chain/kinetics[16]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 82 7 0 simundump kpool /kinetics/chain/kinetics[16]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 77 4 0 simundump kreac /kinetics/chain/kinetics[16]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 78 7 0 simundump kpool /kinetics/chain/kinetics[16]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 73 6 0 simundump kenz /kinetics/chain/kinetics[16]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 76 6 0 simundump kenz /kinetics/chain/kinetics[16]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 79 6 0 simundump kreac /kinetics/chain/kinetics[16]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 74 9 0 simundump kpool /kinetics/chain/kinetics[16]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 73 5 0 simundump kenz /kinetics/chain/kinetics[16]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 76 \ 5 0 simundump kenz /kinetics/chain/kinetics[16]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 79 5 0 simundump kreac /kinetics/chain/kinetics[16]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 74 8 0 simundump kpool /kinetics/chain/kinetics[16]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 73 2 0 simundump kenz /kinetics/chain/kinetics[16]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 74 3 0 simundump kenz /kinetics/chain/kinetics[16]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 79 \ 3 0 simundump kreac /kinetics/chain/kinetics[16]/MKP-1/diff 0 0.101 0.001 "" \ white black 74 5 0 simundump kreac /kinetics/chain/kinetics[16]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 71 9 0 simundump kpool /kinetics/chain/kinetics[16]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 77 9 0 simundump kenz /kinetics/chain/kinetics[16]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 76 10 0 simundump kenz /kinetics/chain/kinetics[16]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 79 7 0 simundump kenz /kinetics/chain/kinetics[16]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 76 7 0 simundump kenz /kinetics/chain/kinetics[16]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 80 10 0 simundump kreac /kinetics/chain/kinetics[16]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 78 12 0 simundump group /kinetics/chain/kinetics[16]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 82.513 16.351 0 simundump kreac /kinetics/chain/kinetics[16]/Ras/dephosph-GEF 1 1 0 "" white \ blue 77.07 17.881 0 simundump kpool /kinetics/chain/kinetics[16]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 80.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[16]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 80 17 0 simundump kreac /kinetics/chain/kinetics[16]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 81.453 21.352 0 simundump kpool /kinetics/chain/kinetics[16]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 74.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[16]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 75.086 16.086 0 simundump kreac /kinetics/chain/kinetics[16]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 75.448 20.246 0 simundump kpool /kinetics/chain/kinetics[16]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 80.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[16]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 81.564 16.084 0 simundump kpool /kinetics/chain/kinetics[16]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 74.131 14.165 0 simundump kreac /kinetics/chain/kinetics[16]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 75.131 17.165 0 simundump kreac /kinetics/chain/kinetics[16]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 77.098 13.5 0 simundump kreac /kinetics/chain/kinetics[16]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 72.023 15.524 0 simundump kpool /kinetics/chain/kinetics[16]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 69.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[16]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 70.35 17.349 0 simundump kpool /kinetics/chain/kinetics[16]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 74.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[16]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 77.012 12.403 0 simundump kreac /kinetics/chain/kinetics[16]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 75.655 15.338 0 simundump kreac /kinetics/chain/kinetics[16]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 70.486 21.679 0 simundump kpool /kinetics/chain/kinetics[16]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 73.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[16]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 73.022 18.657 0 simundump kreac /kinetics/chain/kinetics[16]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 74.345 22.58 0 simundump group /kinetics/chain/kinetics[16]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 58 21 0 simundump kpool /kinetics/chain/kinetics[16]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 55 30 0 simundump kreac /kinetics/chain/kinetics[16]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 56 33 0 simundump kreac /kinetics/chain/kinetics[16]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 57.6 23.26 0 simundump kpool /kinetics/chain/kinetics[16]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 61.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[16]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 62.489 27.397 0 simundump kpool /kinetics/chain/kinetics[16]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 66 24 0 simundump kreac /kinetics/chain/kinetics[16]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 67 27 0 simundump kreac /kinetics/chain/kinetics[16]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 58 30 0 simundump kpool /kinetics/chain/kinetics[16]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 62.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[16]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 63.999 30.258 0 simundump kreac /kinetics/chain/kinetics[16]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 59.158 26.225 0 simundump kreac /kinetics/chain/kinetics[16]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 64 30 0 simundump kpool /kinetics/chain/kinetics[16]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 61 31 0 simundump kreac /kinetics/chain/kinetics[16]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 62 34 0 simundump kpool /kinetics/chain/kinetics[16]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 50 23 0 simundump kreac /kinetics/chain/kinetics[16]/Ca/diff 0 0.101 0.001 "" white \ black 51 26 0 simundump kreac /kinetics/chain/kinetics[16]/Ras-act-unphosph-raf 0 0 0 "" \ white black 72 8 0 simundump group /kinetics/chain/kinetics[16]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 61 19 0 simundump kpool /kinetics/chain/kinetics[16]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 57 17 0 simundump kreac /kinetics/chain/kinetics[16]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 58 20 0 simundump kpool /kinetics/chain/kinetics[16]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 57 9 0 simundump kenz /kinetics/chain/kinetics[16]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 58 10 0 simundump kreac /kinetics/chain/kinetics[16]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 58 12 0 simundump kpool /kinetics/chain/kinetics[16]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 61 12 0 simundump kreac /kinetics/chain/kinetics[16]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 60 7 0 simundump kpool /kinetics/chain/kinetics[16]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 56 5 0 simundump kpool /kinetics/chain/kinetics[16]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 56 \ 14 0 simundump kenz /kinetics/chain/kinetics[16]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 56 13 0 simundump kreac /kinetics/chain/kinetics[16]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 57 17 0 simundump kpool /kinetics/chain/kinetics[16]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 53 12 0 simundump kreac /kinetics/chain/kinetics[16]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 54 15 0 simundump kreac /kinetics/chain/kinetics[16]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 51 9 0 simundump kreac /kinetics/chain/kinetics[16]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 51 16 0 simundump kpool /kinetics/chain/kinetics[16]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 50 30 0 simundump kreac /kinetics/chain/kinetics[16]/Ca_diff 0 5 5 "" white black 50 \ 26 0 simundump group /kinetics/chain/kinetics[17] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 72 0 0 simundump group /kinetics/chain/kinetics[17]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 68.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[17]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 67.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[17]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 68.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[17]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 67.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[17]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 69.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[17]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 68.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[17]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 69.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[17]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 69.221 6.529 0 simundump kreac /kinetics/chain/kinetics[17]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 70.221 9.529 0 simundump kpool /kinetics/chain/kinetics[17]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 70.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[17]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 71.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[17]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 72.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[17]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 73.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[17]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 68.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[17]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 71.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[17]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 72.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[17]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 65.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[17]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 66.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[17]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 69 11 0 simundump kreac /kinetics/chain/kinetics[17]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 70 14 0 simundump kpool /kinetics/chain/kinetics[17]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 76 -3 0 simundump kpool /kinetics/chain/kinetics[17]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 72 9 0 simundump kenz /kinetics/chain/kinetics[17]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 78 10 0 simundump kenz /kinetics/chain/kinetics[17]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 76 13 0 simundump kenz /kinetics/chain/kinetics[17]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 81 20 0 simundump kpool /kinetics/chain/kinetics[17]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 85 1 \ 0 simundump kenz /kinetics/chain/kinetics[17]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 82 \ 10 0 simundump kreac /kinetics/chain/kinetics[17]/MAPK*/diff 0 0.101 0.001 "" \ white black 86 4 0 simundump group /kinetics/chain/kinetics[17]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 87 11 0 simundump kpool /kinetics/chain/kinetics[17]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 78 8 0 simundump kreac /kinetics/chain/kinetics[17]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 79 11 0 simundump kpool /kinetics/chain/kinetics[17]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 81 8 0 simundump kreac /kinetics/chain/kinetics[17]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 82 11 0 simundump kpool /kinetics/chain/kinetics[17]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 78 4 0 simundump kreac /kinetics/chain/kinetics[17]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 79 7 0 simundump kpool /kinetics/chain/kinetics[17]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 78 1 0 simundump kreac /kinetics/chain/kinetics[17]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 79 4 0 simundump kpool /kinetics/chain/kinetics[17]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 84 8 0 simundump kreac /kinetics/chain/kinetics[17]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 85 11 0 simundump kpool /kinetics/chain/kinetics[17]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 81 1 0 simundump kreac /kinetics/chain/kinetics[17]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 82 4 0 simundump kpool /kinetics/chain/kinetics[17]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 85 4 0 simundump kenz /kinetics/chain/kinetics[17]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 80 3 0 simundump kenz /kinetics/chain/kinetics[17]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 85 3 \ 0 simundump kreac /kinetics/chain/kinetics[17]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 86 7 0 simundump kpool /kinetics/chain/kinetics[17]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 81 4 0 simundump kreac /kinetics/chain/kinetics[17]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 82 7 0 simundump kpool /kinetics/chain/kinetics[17]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 77 6 0 simundump kenz /kinetics/chain/kinetics[17]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 80 6 0 simundump kenz /kinetics/chain/kinetics[17]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 83 6 0 simundump kreac /kinetics/chain/kinetics[17]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 78 9 0 simundump kpool /kinetics/chain/kinetics[17]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 77 5 0 simundump kenz /kinetics/chain/kinetics[17]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 80 \ 5 0 simundump kenz /kinetics/chain/kinetics[17]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 83 5 0 simundump kreac /kinetics/chain/kinetics[17]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 78 8 0 simundump kpool /kinetics/chain/kinetics[17]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 77 2 0 simundump kenz /kinetics/chain/kinetics[17]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 78 3 0 simundump kenz /kinetics/chain/kinetics[17]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 83 \ 3 0 simundump kreac /kinetics/chain/kinetics[17]/MKP-1/diff 0 0.101 0.001 "" \ white black 78 5 0 simundump kreac /kinetics/chain/kinetics[17]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 75 9 0 simundump kpool /kinetics/chain/kinetics[17]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 81 9 0 simundump kenz /kinetics/chain/kinetics[17]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 80 10 0 simundump kenz /kinetics/chain/kinetics[17]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 83 7 0 simundump kenz /kinetics/chain/kinetics[17]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 80 7 0 simundump kenz /kinetics/chain/kinetics[17]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 84 10 0 simundump kreac /kinetics/chain/kinetics[17]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 82 12 0 simundump group /kinetics/chain/kinetics[17]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 86.513 16.351 0 simundump kreac /kinetics/chain/kinetics[17]/Ras/dephosph-GEF 1 1 0 "" white \ blue 81.07 17.881 0 simundump kpool /kinetics/chain/kinetics[17]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 84.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[17]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 84 17 0 simundump kreac /kinetics/chain/kinetics[17]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 85.453 21.352 0 simundump kpool /kinetics/chain/kinetics[17]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 78.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[17]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 79.086 16.086 0 simundump kreac /kinetics/chain/kinetics[17]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 79.448 20.246 0 simundump kpool /kinetics/chain/kinetics[17]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 84.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[17]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 85.564 16.084 0 simundump kpool /kinetics/chain/kinetics[17]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 78.131 14.165 0 simundump kreac /kinetics/chain/kinetics[17]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 79.131 17.165 0 simundump kreac /kinetics/chain/kinetics[17]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 81.098 13.5 0 simundump kreac /kinetics/chain/kinetics[17]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 76.023 15.524 0 simundump kpool /kinetics/chain/kinetics[17]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 73.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[17]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 74.35 17.349 0 simundump kpool /kinetics/chain/kinetics[17]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 78.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[17]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 81.012 12.403 0 simundump kreac /kinetics/chain/kinetics[17]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 79.655 15.338 0 simundump kreac /kinetics/chain/kinetics[17]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 74.486 21.679 0 simundump kpool /kinetics/chain/kinetics[17]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 77.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[17]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 77.022 18.657 0 simundump kreac /kinetics/chain/kinetics[17]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 78.345 22.58 0 simundump group /kinetics/chain/kinetics[17]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 62 21 0 simundump kpool /kinetics/chain/kinetics[17]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 59 30 0 simundump kreac /kinetics/chain/kinetics[17]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 60 33 0 simundump kreac /kinetics/chain/kinetics[17]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 61.6 23.26 0 simundump kpool /kinetics/chain/kinetics[17]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 65.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[17]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 66.489 27.397 0 simundump kpool /kinetics/chain/kinetics[17]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 70 24 0 simundump kreac /kinetics/chain/kinetics[17]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 71 27 0 simundump kreac /kinetics/chain/kinetics[17]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 62 30 0 simundump kpool /kinetics/chain/kinetics[17]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 66.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[17]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 67.999 30.258 0 simundump kreac /kinetics/chain/kinetics[17]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 63.158 26.225 0 simundump kreac /kinetics/chain/kinetics[17]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 68 30 0 simundump kpool /kinetics/chain/kinetics[17]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 65 31 0 simundump kreac /kinetics/chain/kinetics[17]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 66 34 0 simundump kpool /kinetics/chain/kinetics[17]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 54 23 0 simundump kreac /kinetics/chain/kinetics[17]/Ca/diff 0 0.101 0.001 "" white \ black 55 26 0 simundump kreac /kinetics/chain/kinetics[17]/Ras-act-unphosph-raf 0 0 0 "" \ white black 76 8 0 simundump group /kinetics/chain/kinetics[17]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 65 19 0 simundump kpool /kinetics/chain/kinetics[17]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 61 17 0 simundump kreac /kinetics/chain/kinetics[17]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 62 20 0 simundump kpool /kinetics/chain/kinetics[17]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 61 9 0 simundump kenz /kinetics/chain/kinetics[17]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 62 10 0 simundump kreac /kinetics/chain/kinetics[17]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 62 12 0 simundump kpool /kinetics/chain/kinetics[17]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 65 12 0 simundump kreac /kinetics/chain/kinetics[17]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 64 7 0 simundump kpool /kinetics/chain/kinetics[17]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 60 5 0 simundump kpool /kinetics/chain/kinetics[17]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 60 \ 14 0 simundump kenz /kinetics/chain/kinetics[17]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 60 13 0 simundump kreac /kinetics/chain/kinetics[17]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 61 17 0 simundump kpool /kinetics/chain/kinetics[17]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 57 12 0 simundump kreac /kinetics/chain/kinetics[17]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 58 15 0 simundump kreac /kinetics/chain/kinetics[17]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 55 9 0 simundump kreac /kinetics/chain/kinetics[17]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 55 16 0 simundump kpool /kinetics/chain/kinetics[17]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 54 30 0 simundump kreac /kinetics/chain/kinetics[17]/Ca_diff 0 5 5 "" white black 54 \ 26 0 simundump group /kinetics/chain/kinetics[18] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 76 0 0 simundump group /kinetics/chain/kinetics[18]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 72.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[18]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 71.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[18]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 72.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[18]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 71.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[18]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 73.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[18]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 72.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[18]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 73.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[18]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 73.221 6.529 0 simundump kreac /kinetics/chain/kinetics[18]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 74.221 9.529 0 simundump kpool /kinetics/chain/kinetics[18]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 74.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[18]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 75.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[18]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 76.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[18]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 77.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[18]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 72.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[18]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 75.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[18]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 76.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[18]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 69.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[18]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 70.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[18]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 73 11 0 simundump kreac /kinetics/chain/kinetics[18]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 74 14 0 simundump kpool /kinetics/chain/kinetics[18]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 80 -3 0 simundump kpool /kinetics/chain/kinetics[18]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 76 9 0 simundump kenz /kinetics/chain/kinetics[18]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 82 10 0 simundump kenz /kinetics/chain/kinetics[18]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 80 13 0 simundump kenz /kinetics/chain/kinetics[18]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 85 20 0 simundump kpool /kinetics/chain/kinetics[18]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 89 1 \ 0 simundump kenz /kinetics/chain/kinetics[18]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 86 \ 10 0 simundump kreac /kinetics/chain/kinetics[18]/MAPK*/diff 0 0.101 0.001 "" \ white black 90 4 0 simundump group /kinetics/chain/kinetics[18]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 91 11 0 simundump kpool /kinetics/chain/kinetics[18]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 82 8 0 simundump kreac /kinetics/chain/kinetics[18]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 83 11 0 simundump kpool /kinetics/chain/kinetics[18]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 85 8 0 simundump kreac /kinetics/chain/kinetics[18]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 86 11 0 simundump kpool /kinetics/chain/kinetics[18]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 82 4 0 simundump kreac /kinetics/chain/kinetics[18]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 83 7 0 simundump kpool /kinetics/chain/kinetics[18]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 82 1 0 simundump kreac /kinetics/chain/kinetics[18]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 83 4 0 simundump kpool /kinetics/chain/kinetics[18]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 88 8 0 simundump kreac /kinetics/chain/kinetics[18]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 89 11 0 simundump kpool /kinetics/chain/kinetics[18]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 85 1 0 simundump kreac /kinetics/chain/kinetics[18]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 86 4 0 simundump kpool /kinetics/chain/kinetics[18]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 89 4 0 simundump kenz /kinetics/chain/kinetics[18]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 84 3 0 simundump kenz /kinetics/chain/kinetics[18]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 89 3 \ 0 simundump kreac /kinetics/chain/kinetics[18]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 90 7 0 simundump kpool /kinetics/chain/kinetics[18]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 85 4 0 simundump kreac /kinetics/chain/kinetics[18]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 86 7 0 simundump kpool /kinetics/chain/kinetics[18]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 81 6 0 simundump kenz /kinetics/chain/kinetics[18]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 84 6 0 simundump kenz /kinetics/chain/kinetics[18]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 87 6 0 simundump kreac /kinetics/chain/kinetics[18]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 82 9 0 simundump kpool /kinetics/chain/kinetics[18]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 81 5 0 simundump kenz /kinetics/chain/kinetics[18]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 84 \ 5 0 simundump kenz /kinetics/chain/kinetics[18]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 87 5 0 simundump kreac /kinetics/chain/kinetics[18]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 82 8 0 simundump kpool /kinetics/chain/kinetics[18]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 81 2 0 simundump kenz /kinetics/chain/kinetics[18]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 82 3 0 simundump kenz /kinetics/chain/kinetics[18]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 87 \ 3 0 simundump kreac /kinetics/chain/kinetics[18]/MKP-1/diff 0 0.101 0.001 "" \ white black 82 5 0 simundump kreac /kinetics/chain/kinetics[18]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 79 9 0 simundump kpool /kinetics/chain/kinetics[18]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 85 9 0 simundump kenz /kinetics/chain/kinetics[18]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 84 10 0 simundump kenz /kinetics/chain/kinetics[18]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 87 7 0 simundump kenz /kinetics/chain/kinetics[18]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 84 7 0 simundump kenz /kinetics/chain/kinetics[18]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 88 10 0 simundump kreac /kinetics/chain/kinetics[18]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 86 12 0 simundump group /kinetics/chain/kinetics[18]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 90.513 16.351 0 simundump kreac /kinetics/chain/kinetics[18]/Ras/dephosph-GEF 1 1 0 "" white \ blue 85.07 17.881 0 simundump kpool /kinetics/chain/kinetics[18]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 88.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[18]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 88 17 0 simundump kreac /kinetics/chain/kinetics[18]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 89.453 21.352 0 simundump kpool /kinetics/chain/kinetics[18]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 82.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[18]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 83.086 16.086 0 simundump kreac /kinetics/chain/kinetics[18]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 83.448 20.246 0 simundump kpool /kinetics/chain/kinetics[18]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 88.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[18]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 89.564 16.084 0 simundump kpool /kinetics/chain/kinetics[18]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 82.131 14.165 0 simundump kreac /kinetics/chain/kinetics[18]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 83.131 17.165 0 simundump kreac /kinetics/chain/kinetics[18]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 85.098 13.5 0 simundump kreac /kinetics/chain/kinetics[18]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 80.023 15.524 0 simundump kpool /kinetics/chain/kinetics[18]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 77.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[18]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 78.35 17.349 0 simundump kpool /kinetics/chain/kinetics[18]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 82.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[18]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 85.012 12.403 0 simundump kreac /kinetics/chain/kinetics[18]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 83.655 15.338 0 simundump kreac /kinetics/chain/kinetics[18]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 78.486 21.679 0 simundump kpool /kinetics/chain/kinetics[18]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 81.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[18]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 81.022 18.657 0 simundump kreac /kinetics/chain/kinetics[18]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 82.345 22.58 0 simundump group /kinetics/chain/kinetics[18]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 66 21 0 simundump kpool /kinetics/chain/kinetics[18]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 63 30 0 simundump kreac /kinetics/chain/kinetics[18]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 64 33 0 simundump kreac /kinetics/chain/kinetics[18]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 65.6 23.26 0 simundump kpool /kinetics/chain/kinetics[18]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 69.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[18]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 70.489 27.397 0 simundump kpool /kinetics/chain/kinetics[18]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 74 24 0 simundump kreac /kinetics/chain/kinetics[18]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 75 27 0 simundump kreac /kinetics/chain/kinetics[18]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 66 30 0 simundump kpool /kinetics/chain/kinetics[18]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 70.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[18]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 71.999 30.258 0 simundump kreac /kinetics/chain/kinetics[18]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 67.158 26.225 0 simundump kreac /kinetics/chain/kinetics[18]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 72 30 0 simundump kpool /kinetics/chain/kinetics[18]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 69 31 0 simundump kreac /kinetics/chain/kinetics[18]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 70 34 0 simundump kpool /kinetics/chain/kinetics[18]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 58 23 0 simundump kreac /kinetics/chain/kinetics[18]/Ca/diff 0 0.101 0.001 "" white \ black 59 26 0 simundump kreac /kinetics/chain/kinetics[18]/Ras-act-unphosph-raf 0 0 0 "" \ white black 80 8 0 simundump group /kinetics/chain/kinetics[18]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 69 19 0 simundump kpool /kinetics/chain/kinetics[18]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 65 17 0 simundump kreac /kinetics/chain/kinetics[18]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 66 20 0 simundump kpool /kinetics/chain/kinetics[18]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 65 9 0 simundump kenz /kinetics/chain/kinetics[18]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 66 10 0 simundump kreac /kinetics/chain/kinetics[18]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 66 12 0 simundump kpool /kinetics/chain/kinetics[18]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 69 12 0 simundump kreac /kinetics/chain/kinetics[18]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 68 7 0 simundump kpool /kinetics/chain/kinetics[18]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 64 5 0 simundump kpool /kinetics/chain/kinetics[18]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 64 \ 14 0 simundump kenz /kinetics/chain/kinetics[18]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 64 13 0 simundump kreac /kinetics/chain/kinetics[18]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 65 17 0 simundump kpool /kinetics/chain/kinetics[18]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 61 12 0 simundump kreac /kinetics/chain/kinetics[18]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 62 15 0 simundump kreac /kinetics/chain/kinetics[18]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 59 9 0 simundump kreac /kinetics/chain/kinetics[18]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 59 16 0 simundump kpool /kinetics/chain/kinetics[18]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 58 30 0 simundump kreac /kinetics/chain/kinetics[18]/Ca_diff 0 5 5 "" white black 58 \ 26 0 simundump group /kinetics/chain/kinetics[19] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 80 0 0 simundump group /kinetics/chain/kinetics[19]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 76.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[19]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 75.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[19]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 76.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[19]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 75.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[19]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 77.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[19]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 76.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[19]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 77.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[19]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 77.221 6.529 0 simundump kreac /kinetics/chain/kinetics[19]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 78.221 9.529 0 simundump kpool /kinetics/chain/kinetics[19]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 78.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[19]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 79.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[19]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 80.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[19]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 81.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[19]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 76.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[19]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 79.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[19]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 80.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[19]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 73.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[19]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 74.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[19]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 77 11 0 simundump kreac /kinetics/chain/kinetics[19]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 78 14 0 simundump kpool /kinetics/chain/kinetics[19]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 84 -3 0 simundump kpool /kinetics/chain/kinetics[19]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 80 9 0 simundump kenz /kinetics/chain/kinetics[19]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 86 10 0 simundump kenz /kinetics/chain/kinetics[19]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 84 13 0 simundump kenz /kinetics/chain/kinetics[19]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 89 20 0 simundump kpool /kinetics/chain/kinetics[19]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 93 1 \ 0 simundump kenz /kinetics/chain/kinetics[19]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 90 \ 10 0 simundump kreac /kinetics/chain/kinetics[19]/MAPK*/diff 0 0.101 0.001 "" \ white black 94 4 0 simundump group /kinetics/chain/kinetics[19]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 95 11 0 simundump kpool /kinetics/chain/kinetics[19]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 86 8 0 simundump kreac /kinetics/chain/kinetics[19]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 87 11 0 simundump kpool /kinetics/chain/kinetics[19]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 89 8 0 simundump kreac /kinetics/chain/kinetics[19]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 90 11 0 simundump kpool /kinetics/chain/kinetics[19]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 86 4 0 simundump kreac /kinetics/chain/kinetics[19]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 87 7 0 simundump kpool /kinetics/chain/kinetics[19]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 86 1 0 simundump kreac /kinetics/chain/kinetics[19]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 87 4 0 simundump kpool /kinetics/chain/kinetics[19]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 92 8 0 simundump kreac /kinetics/chain/kinetics[19]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 93 11 0 simundump kpool /kinetics/chain/kinetics[19]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 89 1 0 simundump kreac /kinetics/chain/kinetics[19]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 90 4 0 simundump kpool /kinetics/chain/kinetics[19]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 93 4 0 simundump kenz /kinetics/chain/kinetics[19]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 88 3 0 simundump kenz /kinetics/chain/kinetics[19]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 93 3 \ 0 simundump kreac /kinetics/chain/kinetics[19]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 94 7 0 simundump kpool /kinetics/chain/kinetics[19]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 89 4 0 simundump kreac /kinetics/chain/kinetics[19]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 90 7 0 simundump kpool /kinetics/chain/kinetics[19]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 85 6 0 simundump kenz /kinetics/chain/kinetics[19]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 88 6 0 simundump kenz /kinetics/chain/kinetics[19]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 91 6 0 simundump kreac /kinetics/chain/kinetics[19]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 86 9 0 simundump kpool /kinetics/chain/kinetics[19]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 85 5 0 simundump kenz /kinetics/chain/kinetics[19]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 88 \ 5 0 simundump kenz /kinetics/chain/kinetics[19]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 91 5 0 simundump kreac /kinetics/chain/kinetics[19]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 86 8 0 simundump kpool /kinetics/chain/kinetics[19]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 85 2 0 simundump kenz /kinetics/chain/kinetics[19]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 86 3 0 simundump kenz /kinetics/chain/kinetics[19]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 91 \ 3 0 simundump kreac /kinetics/chain/kinetics[19]/MKP-1/diff 0 0.101 0.001 "" \ white black 86 5 0 simundump kreac /kinetics/chain/kinetics[19]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 83 9 0 simundump kpool /kinetics/chain/kinetics[19]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 89 9 0 simundump kenz /kinetics/chain/kinetics[19]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 88 10 0 simundump kenz /kinetics/chain/kinetics[19]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 91 7 0 simundump kenz /kinetics/chain/kinetics[19]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 88 7 0 simundump kenz /kinetics/chain/kinetics[19]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 92 10 0 simundump kreac /kinetics/chain/kinetics[19]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 90 12 0 simundump group /kinetics/chain/kinetics[19]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 94.513 16.351 0 simundump kreac /kinetics/chain/kinetics[19]/Ras/dephosph-GEF 1 1 0 "" white \ blue 89.07 17.881 0 simundump kpool /kinetics/chain/kinetics[19]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 92.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[19]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 92 17 0 simundump kreac /kinetics/chain/kinetics[19]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 93.453 21.352 0 simundump kpool /kinetics/chain/kinetics[19]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 86.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[19]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 87.086 16.086 0 simundump kreac /kinetics/chain/kinetics[19]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 87.448 20.246 0 simundump kpool /kinetics/chain/kinetics[19]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 92.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[19]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 93.564 16.084 0 simundump kpool /kinetics/chain/kinetics[19]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 86.131 14.165 0 simundump kreac /kinetics/chain/kinetics[19]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 87.131 17.165 0 simundump kreac /kinetics/chain/kinetics[19]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 89.098 13.5 0 simundump kreac /kinetics/chain/kinetics[19]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 84.023 15.524 0 simundump kpool /kinetics/chain/kinetics[19]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 81.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[19]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 82.35 17.349 0 simundump kpool /kinetics/chain/kinetics[19]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 86.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[19]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 89.012 12.403 0 simundump kreac /kinetics/chain/kinetics[19]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 87.655 15.338 0 simundump kreac /kinetics/chain/kinetics[19]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 82.486 21.679 0 simundump kpool /kinetics/chain/kinetics[19]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 85.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[19]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 85.022 18.657 0 simundump kreac /kinetics/chain/kinetics[19]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 86.345 22.58 0 simundump group /kinetics/chain/kinetics[19]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 70 21 0 simundump kpool /kinetics/chain/kinetics[19]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 67 30 0 simundump kreac /kinetics/chain/kinetics[19]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 68 33 0 simundump kreac /kinetics/chain/kinetics[19]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 69.6 23.26 0 simundump kpool /kinetics/chain/kinetics[19]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 73.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[19]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 74.489 27.397 0 simundump kpool /kinetics/chain/kinetics[19]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 78 24 0 simundump kreac /kinetics/chain/kinetics[19]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 79 27 0 simundump kreac /kinetics/chain/kinetics[19]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 70 30 0 simundump kpool /kinetics/chain/kinetics[19]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 74.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[19]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 75.999 30.258 0 simundump kreac /kinetics/chain/kinetics[19]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 71.158 26.225 0 simundump kreac /kinetics/chain/kinetics[19]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 76 30 0 simundump kpool /kinetics/chain/kinetics[19]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 73 31 0 simundump kreac /kinetics/chain/kinetics[19]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 74 34 0 simundump kpool /kinetics/chain/kinetics[19]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 62 23 0 simundump kreac /kinetics/chain/kinetics[19]/Ca/diff 0 0.101 0.001 "" white \ black 63 26 0 simundump kreac /kinetics/chain/kinetics[19]/Ras-act-unphosph-raf 0 0 0 "" \ white black 84 8 0 simundump group /kinetics/chain/kinetics[19]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 73 19 0 simundump kpool /kinetics/chain/kinetics[19]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 69 17 0 simundump kreac /kinetics/chain/kinetics[19]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 70 20 0 simundump kpool /kinetics/chain/kinetics[19]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 69 9 0 simundump kenz /kinetics/chain/kinetics[19]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 70 10 0 simundump kreac /kinetics/chain/kinetics[19]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 70 12 0 simundump kpool /kinetics/chain/kinetics[19]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 73 12 0 simundump kreac /kinetics/chain/kinetics[19]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 72 7 0 simundump kpool /kinetics/chain/kinetics[19]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 68 5 0 simundump kpool /kinetics/chain/kinetics[19]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 68 \ 14 0 simundump kenz /kinetics/chain/kinetics[19]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 68 13 0 simundump kreac /kinetics/chain/kinetics[19]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 69 17 0 simundump kpool /kinetics/chain/kinetics[19]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 65 12 0 simundump kreac /kinetics/chain/kinetics[19]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 66 15 0 simundump kreac /kinetics/chain/kinetics[19]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 63 9 0 simundump kreac /kinetics/chain/kinetics[19]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 63 16 0 simundump kpool /kinetics/chain/kinetics[19]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 62 30 0 simundump kreac /kinetics/chain/kinetics[19]/Ca_diff 0 5 5 "" white black 62 \ 26 0 simundump group /kinetics/chain/kinetics[20] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 84 0 0 simundump group /kinetics/chain/kinetics[20]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 80.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[20]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 79.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[20]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 80.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[20]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 79.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[20]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 81.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[20]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 80.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[20]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 81.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[20]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 81.221 6.529 0 simundump kreac /kinetics/chain/kinetics[20]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 82.221 9.529 0 simundump kpool /kinetics/chain/kinetics[20]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 82.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[20]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 83.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[20]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 84.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[20]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 85.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[20]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 80.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[20]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 83.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[20]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 84.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[20]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 77.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[20]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 78.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[20]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 81 11 0 simundump kreac /kinetics/chain/kinetics[20]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 82 14 0 simundump kpool /kinetics/chain/kinetics[20]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 88 -3 0 simundump kpool /kinetics/chain/kinetics[20]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 84 9 0 simundump kenz /kinetics/chain/kinetics[20]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 90 10 0 simundump kenz /kinetics/chain/kinetics[20]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 88 13 0 simundump kenz /kinetics/chain/kinetics[20]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 93 20 0 simundump kpool /kinetics/chain/kinetics[20]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 97 1 \ 0 simundump kenz /kinetics/chain/kinetics[20]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 94 \ 10 0 simundump kreac /kinetics/chain/kinetics[20]/MAPK*/diff 0 0.101 0.001 "" \ white black 98 4 0 simundump group /kinetics/chain/kinetics[20]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 99 11 0 simundump kpool /kinetics/chain/kinetics[20]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 90 8 0 simundump kreac /kinetics/chain/kinetics[20]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 91 11 0 simundump kpool /kinetics/chain/kinetics[20]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 93 8 0 simundump kreac /kinetics/chain/kinetics[20]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 94 11 0 simundump kpool /kinetics/chain/kinetics[20]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 90 4 0 simundump kreac /kinetics/chain/kinetics[20]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 91 7 0 simundump kpool /kinetics/chain/kinetics[20]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 90 1 0 simundump kreac /kinetics/chain/kinetics[20]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 91 4 0 simundump kpool /kinetics/chain/kinetics[20]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 96 8 0 simundump kreac /kinetics/chain/kinetics[20]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 97 11 0 simundump kpool /kinetics/chain/kinetics[20]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 93 1 0 simundump kreac /kinetics/chain/kinetics[20]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 94 4 0 simundump kpool /kinetics/chain/kinetics[20]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 97 4 0 simundump kenz /kinetics/chain/kinetics[20]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 92 3 0 simundump kenz /kinetics/chain/kinetics[20]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 97 3 \ 0 simundump kreac /kinetics/chain/kinetics[20]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 98 7 0 simundump kpool /kinetics/chain/kinetics[20]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 93 4 0 simundump kreac /kinetics/chain/kinetics[20]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 94 7 0 simundump kpool /kinetics/chain/kinetics[20]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 89 6 0 simundump kenz /kinetics/chain/kinetics[20]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 92 6 0 simundump kenz /kinetics/chain/kinetics[20]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 95 6 0 simundump kreac /kinetics/chain/kinetics[20]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 90 9 0 simundump kpool /kinetics/chain/kinetics[20]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 89 5 0 simundump kenz /kinetics/chain/kinetics[20]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 92 \ 5 0 simundump kenz /kinetics/chain/kinetics[20]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 95 5 0 simundump kreac /kinetics/chain/kinetics[20]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 90 8 0 simundump kpool /kinetics/chain/kinetics[20]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 89 2 0 simundump kenz /kinetics/chain/kinetics[20]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 90 3 0 simundump kenz /kinetics/chain/kinetics[20]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 95 \ 3 0 simundump kreac /kinetics/chain/kinetics[20]/MKP-1/diff 0 0.101 0.001 "" \ white black 90 5 0 simundump kreac /kinetics/chain/kinetics[20]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 87 9 0 simundump kpool /kinetics/chain/kinetics[20]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 93 9 0 simundump kenz /kinetics/chain/kinetics[20]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 92 10 0 simundump kenz /kinetics/chain/kinetics[20]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 95 7 0 simundump kenz /kinetics/chain/kinetics[20]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 92 7 0 simundump kenz /kinetics/chain/kinetics[20]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 96 10 0 simundump kreac /kinetics/chain/kinetics[20]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 94 12 0 simundump group /kinetics/chain/kinetics[20]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 98.513 16.351 0 simundump kreac /kinetics/chain/kinetics[20]/Ras/dephosph-GEF 1 1 0 "" white \ blue 93.07 17.881 0 simundump kpool /kinetics/chain/kinetics[20]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 96.453 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[20]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 96 17 0 simundump kreac /kinetics/chain/kinetics[20]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 97.453 21.352 0 simundump kpool /kinetics/chain/kinetics[20]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 90.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[20]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 91.086 16.086 0 simundump kreac /kinetics/chain/kinetics[20]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 91.448 20.246 0 simundump kpool /kinetics/chain/kinetics[20]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 96.564 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[20]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 97.564 16.084 0 simundump kpool /kinetics/chain/kinetics[20]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 90.131 14.165 0 simundump kreac /kinetics/chain/kinetics[20]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 91.131 17.165 0 simundump kreac /kinetics/chain/kinetics[20]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 93.098 13.5 0 simundump kreac /kinetics/chain/kinetics[20]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 88.023 15.524 0 simundump kpool /kinetics/chain/kinetics[20]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 85.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[20]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 86.35 17.349 0 simundump kpool /kinetics/chain/kinetics[20]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 90.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[20]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 93.012 12.403 0 simundump kreac /kinetics/chain/kinetics[20]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 91.655 15.338 0 simundump kreac /kinetics/chain/kinetics[20]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 86.486 21.679 0 simundump kpool /kinetics/chain/kinetics[20]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 89.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[20]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 89.022 18.657 0 simundump kreac /kinetics/chain/kinetics[20]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 90.345 22.58 0 simundump group /kinetics/chain/kinetics[20]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 74 21 0 simundump kpool /kinetics/chain/kinetics[20]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 71 30 0 simundump kreac /kinetics/chain/kinetics[20]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 72 33 0 simundump kreac /kinetics/chain/kinetics[20]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 73.6 23.26 0 simundump kpool /kinetics/chain/kinetics[20]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 77.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[20]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 78.489 27.397 0 simundump kpool /kinetics/chain/kinetics[20]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 82 24 0 simundump kreac /kinetics/chain/kinetics[20]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 83 27 0 simundump kreac /kinetics/chain/kinetics[20]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 74 30 0 simundump kpool /kinetics/chain/kinetics[20]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 78.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[20]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 79.999 30.258 0 simundump kreac /kinetics/chain/kinetics[20]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 75.158 26.225 0 simundump kreac /kinetics/chain/kinetics[20]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 80 30 0 simundump kpool /kinetics/chain/kinetics[20]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 77 31 0 simundump kreac /kinetics/chain/kinetics[20]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 78 34 0 simundump kpool /kinetics/chain/kinetics[20]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 66 23 0 simundump kreac /kinetics/chain/kinetics[20]/Ca/diff 0 0.101 0.001 "" white \ black 67 26 0 simundump kreac /kinetics/chain/kinetics[20]/Ras-act-unphosph-raf 0 0 0 "" \ white black 88 8 0 simundump group /kinetics/chain/kinetics[20]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 77 19 0 simundump kpool /kinetics/chain/kinetics[20]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 73 17 0 simundump kreac /kinetics/chain/kinetics[20]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 74 20 0 simundump kpool /kinetics/chain/kinetics[20]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 73 9 0 simundump kenz /kinetics/chain/kinetics[20]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 74 10 0 simundump kreac /kinetics/chain/kinetics[20]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 74 12 0 simundump kpool /kinetics/chain/kinetics[20]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 77 12 0 simundump kreac /kinetics/chain/kinetics[20]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 76 7 0 simundump kpool /kinetics/chain/kinetics[20]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 72 5 0 simundump kpool /kinetics/chain/kinetics[20]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 72 \ 14 0 simundump kenz /kinetics/chain/kinetics[20]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 72 13 0 simundump kreac /kinetics/chain/kinetics[20]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 73 17 0 simundump kpool /kinetics/chain/kinetics[20]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 69 12 0 simundump kreac /kinetics/chain/kinetics[20]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 70 15 0 simundump kreac /kinetics/chain/kinetics[20]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 67 9 0 simundump kreac /kinetics/chain/kinetics[20]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 67 16 0 simundump kpool /kinetics/chain/kinetics[20]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 66 30 0 simundump kreac /kinetics/chain/kinetics[20]/Ca_diff 0 5 5 "" white black 66 \ 26 0 simundump group /kinetics/chain/kinetics[21] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 88 0 0 simundump group /kinetics/chain/kinetics[21]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 84.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[21]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 83.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[21]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 84.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[21]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 83.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[21]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 85.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[21]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 84.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[21]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 85.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[21]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 85.221 6.529 0 simundump kreac /kinetics/chain/kinetics[21]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 86.221 9.529 0 simundump kpool /kinetics/chain/kinetics[21]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 86.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[21]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 87.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[21]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 88.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[21]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 89.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[21]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 84.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[21]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 87.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[21]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 88.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[21]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 81.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[21]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 82.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[21]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 85 11 0 simundump kreac /kinetics/chain/kinetics[21]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 86 14 0 simundump kpool /kinetics/chain/kinetics[21]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 92 -3 0 simundump kpool /kinetics/chain/kinetics[21]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 88 9 0 simundump kenz /kinetics/chain/kinetics[21]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 94 10 0 simundump kenz /kinetics/chain/kinetics[21]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 92 13 0 simundump kenz /kinetics/chain/kinetics[21]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 97 20 0 simundump kpool /kinetics/chain/kinetics[21]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 101 1 \ 0 simundump kenz /kinetics/chain/kinetics[21]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" 98 \ 10 0 simundump kreac /kinetics/chain/kinetics[21]/MAPK*/diff 0 0.101 0.001 "" \ white black 102 4 0 simundump group /kinetics/chain/kinetics[21]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 103 11 0 simundump kpool /kinetics/chain/kinetics[21]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 94 8 0 simundump kreac /kinetics/chain/kinetics[21]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 95 11 0 simundump kpool /kinetics/chain/kinetics[21]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 97 8 0 simundump kreac /kinetics/chain/kinetics[21]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 98 11 0 simundump kpool /kinetics/chain/kinetics[21]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 94 4 0 simundump kreac /kinetics/chain/kinetics[21]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 95 7 0 simundump kpool /kinetics/chain/kinetics[21]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 94 1 0 simundump kreac /kinetics/chain/kinetics[21]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 95 4 0 simundump kpool /kinetics/chain/kinetics[21]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 100 8 0 simundump kreac /kinetics/chain/kinetics[21]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 101 11 0 simundump kpool /kinetics/chain/kinetics[21]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 97 1 0 simundump kreac /kinetics/chain/kinetics[21]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 98 4 0 simundump kpool /kinetics/chain/kinetics[21]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 101 4 \ 0 simundump kenz /kinetics/chain/kinetics[21]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 96 3 0 simundump kenz /kinetics/chain/kinetics[21]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 101 3 \ 0 simundump kreac /kinetics/chain/kinetics[21]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 102 7 0 simundump kpool /kinetics/chain/kinetics[21]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 97 4 0 simundump kreac /kinetics/chain/kinetics[21]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 98 7 0 simundump kpool /kinetics/chain/kinetics[21]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 93 6 0 simundump kenz /kinetics/chain/kinetics[21]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 96 6 0 simundump kenz /kinetics/chain/kinetics[21]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 99 6 0 simundump kreac /kinetics/chain/kinetics[21]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 94 9 0 simundump kpool /kinetics/chain/kinetics[21]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 93 5 0 simundump kenz /kinetics/chain/kinetics[21]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" 96 \ 5 0 simundump kenz /kinetics/chain/kinetics[21]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 99 5 0 simundump kreac /kinetics/chain/kinetics[21]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 94 8 0 simundump kpool /kinetics/chain/kinetics[21]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 93 2 0 simundump kenz /kinetics/chain/kinetics[21]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 94 3 0 simundump kenz /kinetics/chain/kinetics[21]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 99 \ 3 0 simundump kreac /kinetics/chain/kinetics[21]/MKP-1/diff 0 0.101 0.001 "" \ white black 94 5 0 simundump kreac /kinetics/chain/kinetics[21]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 91 9 0 simundump kpool /kinetics/chain/kinetics[21]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 97 9 0 simundump kenz /kinetics/chain/kinetics[21]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 96 10 0 simundump kenz /kinetics/chain/kinetics[21]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 99 7 0 simundump kenz /kinetics/chain/kinetics[21]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 96 7 0 simundump kenz /kinetics/chain/kinetics[21]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 100 10 0 simundump kreac /kinetics/chain/kinetics[21]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 98 12 0 simundump group /kinetics/chain/kinetics[21]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 102.51 16.351 0 simundump kreac /kinetics/chain/kinetics[21]/Ras/dephosph-GEF 1 1 0 "" white \ blue 97.07 17.881 0 simundump kpool /kinetics/chain/kinetics[21]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 100.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[21]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 100 17 0 simundump kreac /kinetics/chain/kinetics[21]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 101.45 21.352 0 simundump kpool /kinetics/chain/kinetics[21]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 94.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[21]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 95.086 16.086 0 simundump kreac /kinetics/chain/kinetics[21]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 95.448 20.246 0 simundump kpool /kinetics/chain/kinetics[21]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 100.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[21]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 101.56 16.084 0 simundump kpool /kinetics/chain/kinetics[21]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 94.131 14.165 0 simundump kreac /kinetics/chain/kinetics[21]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 95.131 17.165 0 simundump kreac /kinetics/chain/kinetics[21]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 97.098 13.5 0 simundump kreac /kinetics/chain/kinetics[21]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 92.023 15.524 0 simundump kpool /kinetics/chain/kinetics[21]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 89.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[21]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 90.35 17.349 0 simundump kpool /kinetics/chain/kinetics[21]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 94.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[21]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 97.012 12.403 0 simundump kreac /kinetics/chain/kinetics[21]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 95.655 15.338 0 simundump kreac /kinetics/chain/kinetics[21]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 90.486 21.679 0 simundump kpool /kinetics/chain/kinetics[21]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 93.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[21]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 93.022 18.657 0 simundump kreac /kinetics/chain/kinetics[21]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 94.345 22.58 0 simundump group /kinetics/chain/kinetics[21]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 78 21 0 simundump kpool /kinetics/chain/kinetics[21]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 75 30 0 simundump kreac /kinetics/chain/kinetics[21]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 76 33 0 simundump kreac /kinetics/chain/kinetics[21]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 77.6 23.26 0 simundump kpool /kinetics/chain/kinetics[21]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 81.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[21]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 82.489 27.397 0 simundump kpool /kinetics/chain/kinetics[21]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 86 24 0 simundump kreac /kinetics/chain/kinetics[21]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 87 27 0 simundump kreac /kinetics/chain/kinetics[21]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 78 30 0 simundump kpool /kinetics/chain/kinetics[21]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 82.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[21]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 83.999 30.258 0 simundump kreac /kinetics/chain/kinetics[21]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 79.158 26.225 0 simundump kreac /kinetics/chain/kinetics[21]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 84 30 0 simundump kpool /kinetics/chain/kinetics[21]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 81 31 0 simundump kreac /kinetics/chain/kinetics[21]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 82 34 0 simundump kpool /kinetics/chain/kinetics[21]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 70 23 0 simundump kreac /kinetics/chain/kinetics[21]/Ca/diff 0 0.101 0.001 "" white \ black 71 26 0 simundump kreac /kinetics/chain/kinetics[21]/Ras-act-unphosph-raf 0 0 0 "" \ white black 92 8 0 simundump group /kinetics/chain/kinetics[21]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 81 19 0 simundump kpool /kinetics/chain/kinetics[21]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 77 17 0 simundump kreac /kinetics/chain/kinetics[21]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 78 20 0 simundump kpool /kinetics/chain/kinetics[21]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 77 9 0 simundump kenz /kinetics/chain/kinetics[21]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 78 10 0 simundump kreac /kinetics/chain/kinetics[21]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 78 12 0 simundump kpool /kinetics/chain/kinetics[21]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 81 12 0 simundump kreac /kinetics/chain/kinetics[21]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 80 7 0 simundump kpool /kinetics/chain/kinetics[21]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 76 5 0 simundump kpool /kinetics/chain/kinetics[21]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 76 \ 14 0 simundump kenz /kinetics/chain/kinetics[21]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 76 13 0 simundump kreac /kinetics/chain/kinetics[21]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 77 17 0 simundump kpool /kinetics/chain/kinetics[21]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 73 12 0 simundump kreac /kinetics/chain/kinetics[21]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 74 15 0 simundump kreac /kinetics/chain/kinetics[21]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 71 9 0 simundump kreac /kinetics/chain/kinetics[21]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 71 16 0 simundump kpool /kinetics/chain/kinetics[21]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 70 30 0 simundump kreac /kinetics/chain/kinetics[21]/Ca_diff 0 5 5 "" white black 70 \ 26 0 simundump group /kinetics/chain/kinetics[22] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 92 0 0 simundump group /kinetics/chain/kinetics[22]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 88.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[22]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 87.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[22]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 88.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[22]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 87.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[22]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 89.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[22]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 88.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[22]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 89.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[22]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 89.221 6.529 0 simundump kreac /kinetics/chain/kinetics[22]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 90.221 9.529 0 simundump kpool /kinetics/chain/kinetics[22]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 90.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[22]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 91.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[22]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 92.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[22]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 93.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[22]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 88.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[22]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 91.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[22]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 92.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[22]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 85.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[22]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 86.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[22]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 89 11 0 simundump kreac /kinetics/chain/kinetics[22]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 90 14 0 simundump kpool /kinetics/chain/kinetics[22]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 96 -3 0 simundump kpool /kinetics/chain/kinetics[22]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 92 9 0 simundump kenz /kinetics/chain/kinetics[22]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 98 10 0 simundump kenz /kinetics/chain/kinetics[22]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 96 13 0 simundump kenz /kinetics/chain/kinetics[22]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 101 20 0 simundump kpool /kinetics/chain/kinetics[22]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 105 1 \ 0 simundump kenz /kinetics/chain/kinetics[22]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 102 10 0 simundump kreac /kinetics/chain/kinetics[22]/MAPK*/diff 0 0.101 0.001 "" \ white black 106 4 0 simundump group /kinetics/chain/kinetics[22]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 107 11 0 simundump kpool /kinetics/chain/kinetics[22]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 98 8 0 simundump kreac /kinetics/chain/kinetics[22]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 99 11 0 simundump kpool /kinetics/chain/kinetics[22]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 101 8 0 simundump kreac /kinetics/chain/kinetics[22]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 102 11 0 simundump kpool /kinetics/chain/kinetics[22]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 98 4 0 simundump kreac /kinetics/chain/kinetics[22]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 99 7 0 simundump kpool /kinetics/chain/kinetics[22]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 98 1 0 simundump kreac /kinetics/chain/kinetics[22]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 99 4 0 simundump kpool /kinetics/chain/kinetics[22]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 104 8 0 simundump kreac /kinetics/chain/kinetics[22]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 105 11 0 simundump kpool /kinetics/chain/kinetics[22]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 101 1 0 simundump kreac /kinetics/chain/kinetics[22]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 102 4 0 simundump kpool /kinetics/chain/kinetics[22]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 105 4 \ 0 simundump kenz /kinetics/chain/kinetics[22]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 100 3 \ 0 simundump kenz /kinetics/chain/kinetics[22]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 105 3 \ 0 simundump kreac /kinetics/chain/kinetics[22]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 106 7 0 simundump kpool /kinetics/chain/kinetics[22]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 101 4 0 simundump kreac /kinetics/chain/kinetics[22]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 102 7 0 simundump kpool /kinetics/chain/kinetics[22]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 97 6 0 simundump kenz /kinetics/chain/kinetics[22]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 100 6 0 simundump kenz /kinetics/chain/kinetics[22]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 103 6 0 simundump kreac /kinetics/chain/kinetics[22]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 98 9 0 simundump kpool /kinetics/chain/kinetics[22]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 97 5 0 simundump kenz /kinetics/chain/kinetics[22]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 100 5 0 simundump kenz /kinetics/chain/kinetics[22]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 103 5 0 simundump kreac /kinetics/chain/kinetics[22]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 98 8 0 simundump kpool /kinetics/chain/kinetics[22]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 97 2 0 simundump kenz /kinetics/chain/kinetics[22]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 98 3 0 simundump kenz /kinetics/chain/kinetics[22]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 103 3 0 simundump kreac /kinetics/chain/kinetics[22]/MKP-1/diff 0 0.101 0.001 "" \ white black 98 5 0 simundump kreac /kinetics/chain/kinetics[22]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 95 9 0 simundump kpool /kinetics/chain/kinetics[22]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 101 9 0 simundump kenz /kinetics/chain/kinetics[22]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 100 10 0 simundump kenz /kinetics/chain/kinetics[22]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 103 7 0 simundump kenz /kinetics/chain/kinetics[22]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 100 7 0 simundump kenz /kinetics/chain/kinetics[22]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 104 10 0 simundump kreac /kinetics/chain/kinetics[22]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 102 12 0 simundump group /kinetics/chain/kinetics[22]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 106.51 16.351 0 simundump kreac /kinetics/chain/kinetics[22]/Ras/dephosph-GEF 1 1 0 "" white \ blue 101.07 17.881 0 simundump kpool /kinetics/chain/kinetics[22]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 104.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[22]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 104 17 0 simundump kreac /kinetics/chain/kinetics[22]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 105.45 21.352 0 simundump kpool /kinetics/chain/kinetics[22]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 98.448 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[22]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 99.086 16.086 0 simundump kreac /kinetics/chain/kinetics[22]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 99.448 20.246 0 simundump kpool /kinetics/chain/kinetics[22]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 104.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[22]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 105.56 16.084 0 simundump kpool /kinetics/chain/kinetics[22]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 98.131 14.165 0 simundump kreac /kinetics/chain/kinetics[22]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 99.131 17.165 0 simundump kreac /kinetics/chain/kinetics[22]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 101.1 13.5 0 simundump kreac /kinetics/chain/kinetics[22]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 96.023 15.524 0 simundump kpool /kinetics/chain/kinetics[22]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 93.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[22]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 94.35 17.349 0 simundump kpool /kinetics/chain/kinetics[22]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 98.655 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[22]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 101.01 12.403 0 simundump kreac /kinetics/chain/kinetics[22]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 99.655 15.338 0 simundump kreac /kinetics/chain/kinetics[22]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 94.486 21.679 0 simundump kpool /kinetics/chain/kinetics[22]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 97.345 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[22]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 97.022 18.657 0 simundump kreac /kinetics/chain/kinetics[22]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 98.345 22.58 0 simundump group /kinetics/chain/kinetics[22]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 82 21 0 simundump kpool /kinetics/chain/kinetics[22]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 79 30 0 simundump kreac /kinetics/chain/kinetics[22]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 80 33 0 simundump kreac /kinetics/chain/kinetics[22]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 81.6 23.26 0 simundump kpool /kinetics/chain/kinetics[22]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 85.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[22]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 86.489 27.397 0 simundump kpool /kinetics/chain/kinetics[22]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 90 24 0 simundump kreac /kinetics/chain/kinetics[22]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 91 27 0 simundump kreac /kinetics/chain/kinetics[22]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 82 30 0 simundump kpool /kinetics/chain/kinetics[22]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 86.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[22]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 87.999 30.258 0 simundump kreac /kinetics/chain/kinetics[22]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 83.158 26.225 0 simundump kreac /kinetics/chain/kinetics[22]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 88 30 0 simundump kpool /kinetics/chain/kinetics[22]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 85 31 0 simundump kreac /kinetics/chain/kinetics[22]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 86 34 0 simundump kpool /kinetics/chain/kinetics[22]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 74 23 0 simundump kreac /kinetics/chain/kinetics[22]/Ca/diff 0 0.101 0.001 "" white \ black 75 26 0 simundump kreac /kinetics/chain/kinetics[22]/Ras-act-unphosph-raf 0 0 0 "" \ white black 96 8 0 simundump group /kinetics/chain/kinetics[22]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 85 19 0 simundump kpool /kinetics/chain/kinetics[22]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 81 17 0 simundump kreac /kinetics/chain/kinetics[22]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 82 20 0 simundump kpool /kinetics/chain/kinetics[22]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 81 9 0 simundump kenz /kinetics/chain/kinetics[22]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 82 10 0 simundump kreac /kinetics/chain/kinetics[22]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 82 12 0 simundump kpool /kinetics/chain/kinetics[22]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 85 12 0 simundump kreac /kinetics/chain/kinetics[22]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 84 7 0 simundump kpool /kinetics/chain/kinetics[22]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 80 5 0 simundump kpool /kinetics/chain/kinetics[22]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 80 \ 14 0 simundump kenz /kinetics/chain/kinetics[22]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 80 13 0 simundump kreac /kinetics/chain/kinetics[22]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 81 17 0 simundump kpool /kinetics/chain/kinetics[22]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 77 12 0 simundump kreac /kinetics/chain/kinetics[22]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 78 15 0 simundump kreac /kinetics/chain/kinetics[22]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 75 9 0 simundump kreac /kinetics/chain/kinetics[22]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 75 16 0 simundump kpool /kinetics/chain/kinetics[22]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 74 30 0 simundump kreac /kinetics/chain/kinetics[22]/Ca_diff 0 5 5 "" white black 74 \ 26 0 simundump group /kinetics/chain/kinetics[23] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 96 0 0 simundump group /kinetics/chain/kinetics[23]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 92.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[23]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 91.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[23]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 92.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[23]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 91.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[23]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 93.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[23]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 92.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[23]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 93.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[23]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 93.221 6.529 0 simundump kreac /kinetics/chain/kinetics[23]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 94.221 9.529 0 simundump kpool /kinetics/chain/kinetics[23]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 94.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[23]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 95.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[23]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 96.231 1.8026 0 simundump kreac /kinetics/chain/kinetics[23]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 97.231 4.8026 0 simundump kreac /kinetics/chain/kinetics[23]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 92.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[23]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 95.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[23]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 96.004 1.9143 0 simundump kpool /kinetics/chain/kinetics[23]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 89.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[23]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 90.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[23]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 93 11 0 simundump kreac /kinetics/chain/kinetics[23]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 94 14 0 simundump kpool /kinetics/chain/kinetics[23]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 100 -3 0 simundump kpool /kinetics/chain/kinetics[23]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 96 9 0 simundump kenz /kinetics/chain/kinetics[23]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 102 10 0 simundump kenz /kinetics/chain/kinetics[23]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 100 13 0 simundump kenz /kinetics/chain/kinetics[23]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 105 20 0 simundump kpool /kinetics/chain/kinetics[23]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 109 1 \ 0 simundump kenz /kinetics/chain/kinetics[23]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 106 10 0 simundump kreac /kinetics/chain/kinetics[23]/MAPK*/diff 0 0.101 0.001 "" \ white black 110 4 0 simundump group /kinetics/chain/kinetics[23]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 111 11 0 simundump kpool /kinetics/chain/kinetics[23]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 102 8 0 simundump kreac /kinetics/chain/kinetics[23]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 103 11 0 simundump kpool /kinetics/chain/kinetics[23]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 105 8 0 simundump kreac /kinetics/chain/kinetics[23]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 106 11 0 simundump kpool /kinetics/chain/kinetics[23]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 102 4 0 simundump kreac /kinetics/chain/kinetics[23]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 103 7 0 simundump kpool /kinetics/chain/kinetics[23]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 102 1 0 simundump kreac /kinetics/chain/kinetics[23]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 103 4 0 simundump kpool /kinetics/chain/kinetics[23]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 108 8 0 simundump kreac /kinetics/chain/kinetics[23]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 109 11 0 simundump kpool /kinetics/chain/kinetics[23]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 105 1 0 simundump kreac /kinetics/chain/kinetics[23]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 106 4 0 simundump kpool /kinetics/chain/kinetics[23]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 109 4 \ 0 simundump kenz /kinetics/chain/kinetics[23]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 104 3 \ 0 simundump kenz /kinetics/chain/kinetics[23]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 109 3 \ 0 simundump kreac /kinetics/chain/kinetics[23]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 110 7 0 simundump kpool /kinetics/chain/kinetics[23]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 105 4 0 simundump kreac /kinetics/chain/kinetics[23]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 106 7 0 simundump kpool /kinetics/chain/kinetics[23]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 101 6 0 simundump kenz /kinetics/chain/kinetics[23]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 104 6 0 simundump kenz /kinetics/chain/kinetics[23]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 107 6 0 simundump kreac /kinetics/chain/kinetics[23]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 102 9 0 simundump kpool /kinetics/chain/kinetics[23]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 101 5 0 simundump kenz /kinetics/chain/kinetics[23]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 104 5 0 simundump kenz /kinetics/chain/kinetics[23]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 107 5 0 simundump kreac /kinetics/chain/kinetics[23]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 102 8 0 simundump kpool /kinetics/chain/kinetics[23]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 101 2 0 simundump kenz /kinetics/chain/kinetics[23]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 102 3 0 simundump kenz /kinetics/chain/kinetics[23]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 107 3 0 simundump kreac /kinetics/chain/kinetics[23]/MKP-1/diff 0 0.101 0.001 "" \ white black 102 5 0 simundump kreac /kinetics/chain/kinetics[23]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 99 9 0 simundump kpool /kinetics/chain/kinetics[23]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 105 9 0 simundump kenz /kinetics/chain/kinetics[23]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 104 10 0 simundump kenz /kinetics/chain/kinetics[23]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 107 7 0 simundump kenz /kinetics/chain/kinetics[23]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 104 7 0 simundump kenz /kinetics/chain/kinetics[23]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 108 10 0 simundump kreac /kinetics/chain/kinetics[23]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 106 12 0 simundump group /kinetics/chain/kinetics[23]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 110.51 16.351 0 simundump kreac /kinetics/chain/kinetics[23]/Ras/dephosph-GEF 1 1 0 "" white \ blue 105.07 17.881 0 simundump kpool /kinetics/chain/kinetics[23]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 108.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[23]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 108 17 0 simundump kreac /kinetics/chain/kinetics[23]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 109.45 21.352 0 simundump kpool /kinetics/chain/kinetics[23]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 102.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[23]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 103.09 16.086 0 simundump kreac /kinetics/chain/kinetics[23]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 103.45 20.246 0 simundump kpool /kinetics/chain/kinetics[23]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 108.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[23]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 109.56 16.084 0 simundump kpool /kinetics/chain/kinetics[23]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 102.13 14.165 0 simundump kreac /kinetics/chain/kinetics[23]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 103.13 17.165 0 simundump kreac /kinetics/chain/kinetics[23]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 105.1 13.5 0 simundump kreac /kinetics/chain/kinetics[23]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 100.02 15.524 0 simundump kpool /kinetics/chain/kinetics[23]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 97.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[23]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 98.35 17.349 0 simundump kpool /kinetics/chain/kinetics[23]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 102.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[23]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 105.01 12.403 0 simundump kreac /kinetics/chain/kinetics[23]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 103.65 15.338 0 simundump kreac /kinetics/chain/kinetics[23]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 98.486 21.679 0 simundump kpool /kinetics/chain/kinetics[23]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 101.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[23]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 101.02 18.657 0 simundump kreac /kinetics/chain/kinetics[23]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 102.35 22.58 0 simundump group /kinetics/chain/kinetics[23]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 86 21 0 simundump kpool /kinetics/chain/kinetics[23]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 83 30 0 simundump kreac /kinetics/chain/kinetics[23]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 84 33 0 simundump kreac /kinetics/chain/kinetics[23]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 85.6 23.26 0 simundump kpool /kinetics/chain/kinetics[23]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 89.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[23]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 90.489 27.397 0 simundump kpool /kinetics/chain/kinetics[23]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 94 24 0 simundump kreac /kinetics/chain/kinetics[23]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 95 27 0 simundump kreac /kinetics/chain/kinetics[23]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 86 30 0 simundump kpool /kinetics/chain/kinetics[23]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 90.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[23]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 91.999 30.258 0 simundump kreac /kinetics/chain/kinetics[23]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 87.158 26.225 0 simundump kreac /kinetics/chain/kinetics[23]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 92 30 0 simundump kpool /kinetics/chain/kinetics[23]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 89 31 0 simundump kreac /kinetics/chain/kinetics[23]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 90 34 0 simundump kpool /kinetics/chain/kinetics[23]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 78 23 0 simundump kreac /kinetics/chain/kinetics[23]/Ca/diff 0 0.101 0.001 "" white \ black 79 26 0 simundump kreac /kinetics/chain/kinetics[23]/Ras-act-unphosph-raf 0 0 0 "" \ white black 100 8 0 simundump group /kinetics/chain/kinetics[23]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 89 19 0 simundump kpool /kinetics/chain/kinetics[23]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 85 17 0 simundump kreac /kinetics/chain/kinetics[23]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 86 20 0 simundump kpool /kinetics/chain/kinetics[23]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 85 9 0 simundump kenz /kinetics/chain/kinetics[23]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 86 10 0 simundump kreac /kinetics/chain/kinetics[23]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 86 12 0 simundump kpool /kinetics/chain/kinetics[23]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 89 12 0 simundump kreac /kinetics/chain/kinetics[23]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 88 7 0 simundump kpool /kinetics/chain/kinetics[23]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 84 5 0 simundump kpool /kinetics/chain/kinetics[23]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 84 \ 14 0 simundump kenz /kinetics/chain/kinetics[23]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 84 13 0 simundump kreac /kinetics/chain/kinetics[23]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 85 17 0 simundump kpool /kinetics/chain/kinetics[23]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 81 12 0 simundump kreac /kinetics/chain/kinetics[23]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 82 15 0 simundump kreac /kinetics/chain/kinetics[23]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 79 9 0 simundump kreac /kinetics/chain/kinetics[23]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 79 16 0 simundump kpool /kinetics/chain/kinetics[23]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 78 30 0 simundump kreac /kinetics/chain/kinetics[23]/Ca_diff 0 5 5 "" white black 78 \ 26 0 simundump group /kinetics/chain/kinetics[24] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 100 0 0 simundump group /kinetics/chain/kinetics[24]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 96.951 8.2163 0 simundump kpool /kinetics/chain/kinetics[24]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 95.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[24]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 96.925 4.5108 0 simundump kreac /kinetics/chain/kinetics[24]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 95.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[24]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 97.939 0.69395 0 simundump kreac /kinetics/chain/kinetics[24]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 96.203 4.2533 0 simundump kreac /kinetics/chain/kinetics[24]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 97.383 2.7362 0 simundump kpool /kinetics/chain/kinetics[24]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 97.221 6.529 0 simundump kreac /kinetics/chain/kinetics[24]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 98.221 9.529 0 simundump kpool /kinetics/chain/kinetics[24]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 98.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[24]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 99.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[24]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 100.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[24]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 101.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[24]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 96.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[24]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 99.004 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[24]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 100 1.9143 0 simundump kpool /kinetics/chain/kinetics[24]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 93.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[24]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 94.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[24]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 97 11 0 simundump kreac /kinetics/chain/kinetics[24]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 98 14 0 simundump kpool /kinetics/chain/kinetics[24]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 104 -3 0 simundump kpool /kinetics/chain/kinetics[24]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 100 9 0 simundump kenz /kinetics/chain/kinetics[24]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 106 10 0 simundump kenz /kinetics/chain/kinetics[24]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 104 13 0 simundump kenz /kinetics/chain/kinetics[24]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 109 20 0 simundump kpool /kinetics/chain/kinetics[24]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 113 1 \ 0 simundump kenz /kinetics/chain/kinetics[24]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 110 10 0 simundump kreac /kinetics/chain/kinetics[24]/MAPK*/diff 0 0.101 0.001 "" \ white black 114 4 0 simundump group /kinetics/chain/kinetics[24]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 115 11 0 simundump kpool /kinetics/chain/kinetics[24]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 106 8 0 simundump kreac /kinetics/chain/kinetics[24]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 107 11 0 simundump kpool /kinetics/chain/kinetics[24]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 109 8 0 simundump kreac /kinetics/chain/kinetics[24]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 110 11 0 simundump kpool /kinetics/chain/kinetics[24]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 106 4 0 simundump kreac /kinetics/chain/kinetics[24]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 107 7 0 simundump kpool /kinetics/chain/kinetics[24]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 106 1 0 simundump kreac /kinetics/chain/kinetics[24]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 107 4 0 simundump kpool /kinetics/chain/kinetics[24]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 112 8 0 simundump kreac /kinetics/chain/kinetics[24]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 113 11 0 simundump kpool /kinetics/chain/kinetics[24]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 109 1 0 simundump kreac /kinetics/chain/kinetics[24]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 110 4 0 simundump kpool /kinetics/chain/kinetics[24]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 113 4 \ 0 simundump kenz /kinetics/chain/kinetics[24]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 108 3 \ 0 simundump kenz /kinetics/chain/kinetics[24]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 113 3 \ 0 simundump kreac /kinetics/chain/kinetics[24]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 114 7 0 simundump kpool /kinetics/chain/kinetics[24]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 109 4 0 simundump kreac /kinetics/chain/kinetics[24]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 110 7 0 simundump kpool /kinetics/chain/kinetics[24]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 105 6 0 simundump kenz /kinetics/chain/kinetics[24]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 108 6 0 simundump kenz /kinetics/chain/kinetics[24]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 111 6 0 simundump kreac /kinetics/chain/kinetics[24]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 106 9 0 simundump kpool /kinetics/chain/kinetics[24]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 105 5 0 simundump kenz /kinetics/chain/kinetics[24]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 108 5 0 simundump kenz /kinetics/chain/kinetics[24]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 111 5 0 simundump kreac /kinetics/chain/kinetics[24]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 106 8 0 simundump kpool /kinetics/chain/kinetics[24]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 105 2 0 simundump kenz /kinetics/chain/kinetics[24]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 106 3 0 simundump kenz /kinetics/chain/kinetics[24]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 111 3 0 simundump kreac /kinetics/chain/kinetics[24]/MKP-1/diff 0 0.101 0.001 "" \ white black 106 5 0 simundump kreac /kinetics/chain/kinetics[24]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 103 9 0 simundump kpool /kinetics/chain/kinetics[24]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 109 9 0 simundump kenz /kinetics/chain/kinetics[24]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 108 10 0 simundump kenz /kinetics/chain/kinetics[24]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 111 7 0 simundump kenz /kinetics/chain/kinetics[24]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 108 7 0 simundump kenz /kinetics/chain/kinetics[24]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 112 10 0 simundump kreac /kinetics/chain/kinetics[24]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 110 12 0 simundump group /kinetics/chain/kinetics[24]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 114.51 16.351 0 simundump kreac /kinetics/chain/kinetics[24]/Ras/dephosph-GEF 1 1 0 "" white \ blue 109.07 17.881 0 simundump kpool /kinetics/chain/kinetics[24]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 112.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[24]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 112 17 0 simundump kreac /kinetics/chain/kinetics[24]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 113.45 21.352 0 simundump kpool /kinetics/chain/kinetics[24]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 106.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[24]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 107.09 16.086 0 simundump kreac /kinetics/chain/kinetics[24]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 107.45 20.246 0 simundump kpool /kinetics/chain/kinetics[24]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 112.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[24]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 113.56 16.084 0 simundump kpool /kinetics/chain/kinetics[24]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 106.13 14.165 0 simundump kreac /kinetics/chain/kinetics[24]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 107.13 17.165 0 simundump kreac /kinetics/chain/kinetics[24]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 109.1 13.5 0 simundump kreac /kinetics/chain/kinetics[24]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 104.02 15.524 0 simundump kpool /kinetics/chain/kinetics[24]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 101.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[24]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 102.35 17.349 0 simundump kpool /kinetics/chain/kinetics[24]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 106.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[24]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 109.01 12.403 0 simundump kreac /kinetics/chain/kinetics[24]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 107.65 15.338 0 simundump kreac /kinetics/chain/kinetics[24]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 102.49 21.679 0 simundump kpool /kinetics/chain/kinetics[24]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 105.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[24]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 105.02 18.657 0 simundump kreac /kinetics/chain/kinetics[24]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 106.35 22.58 0 simundump group /kinetics/chain/kinetics[24]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 90 21 0 simundump kpool /kinetics/chain/kinetics[24]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 87 30 0 simundump kreac /kinetics/chain/kinetics[24]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 88 33 0 simundump kreac /kinetics/chain/kinetics[24]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 89.6 23.26 0 simundump kpool /kinetics/chain/kinetics[24]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 93.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[24]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 94.489 27.397 0 simundump kpool /kinetics/chain/kinetics[24]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 98 24 0 simundump kreac /kinetics/chain/kinetics[24]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 99 27 0 simundump kreac /kinetics/chain/kinetics[24]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 90 30 0 simundump kpool /kinetics/chain/kinetics[24]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 94.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[24]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 95.999 30.258 0 simundump kreac /kinetics/chain/kinetics[24]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 91.158 26.225 0 simundump kreac /kinetics/chain/kinetics[24]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 96 30 0 simundump kpool /kinetics/chain/kinetics[24]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 93 31 0 simundump kreac /kinetics/chain/kinetics[24]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 94 34 0 simundump kpool /kinetics/chain/kinetics[24]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 82 23 0 simundump kreac /kinetics/chain/kinetics[24]/Ca/diff 0 0.101 0.001 "" white \ black 83 26 0 simundump kreac /kinetics/chain/kinetics[24]/Ras-act-unphosph-raf 0 0 0 "" \ white black 104 8 0 simundump group /kinetics/chain/kinetics[24]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 93 19 0 simundump kpool /kinetics/chain/kinetics[24]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 89 17 0 simundump kreac /kinetics/chain/kinetics[24]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 90 20 0 simundump kpool /kinetics/chain/kinetics[24]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 89 9 0 simundump kenz /kinetics/chain/kinetics[24]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 90 10 0 simundump kreac /kinetics/chain/kinetics[24]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 90 12 0 simundump kpool /kinetics/chain/kinetics[24]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 93 12 0 simundump kreac /kinetics/chain/kinetics[24]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 92 7 0 simundump kpool /kinetics/chain/kinetics[24]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 88 5 0 simundump kpool /kinetics/chain/kinetics[24]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 88 \ 14 0 simundump kenz /kinetics/chain/kinetics[24]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 88 13 0 simundump kreac /kinetics/chain/kinetics[24]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 89 17 0 simundump kpool /kinetics/chain/kinetics[24]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 85 12 0 simundump kreac /kinetics/chain/kinetics[24]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 86 15 0 simundump kreac /kinetics/chain/kinetics[24]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 83 9 0 simundump kreac /kinetics/chain/kinetics[24]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 83 16 0 simundump kpool /kinetics/chain/kinetics[24]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 82 30 0 simundump kreac /kinetics/chain/kinetics[24]/Ca_diff 0 5 5 "" white black 82 \ 26 0 simundump group /kinetics/chain/kinetics[25] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 104 0 0 simundump group /kinetics/chain/kinetics[25]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 100.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[25]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 99.925 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[25]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 100.93 4.5108 0 simundump kreac /kinetics/chain/kinetics[25]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 99.925 -0.12295 0 simundump kreac /kinetics/chain/kinetics[25]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 101.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[25]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 100.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[25]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 101.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[25]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 101.22 6.529 0 simundump kreac /kinetics/chain/kinetics[25]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 102.22 9.529 0 simundump kpool /kinetics/chain/kinetics[25]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 102.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[25]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 103.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[25]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 104.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[25]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 105.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[25]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 100.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[25]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 103 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[25]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 104 1.9143 0 simundump kpool /kinetics/chain/kinetics[25]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 97.868 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[25]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 98.868 3.5971 0 simundump kpool /kinetics/chain/kinetics[25]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 101 11 0 simundump kreac /kinetics/chain/kinetics[25]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 102 14 0 simundump kpool /kinetics/chain/kinetics[25]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 108 -3 0 simundump kpool /kinetics/chain/kinetics[25]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 104 9 0 simundump kenz /kinetics/chain/kinetics[25]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 110 10 0 simundump kenz /kinetics/chain/kinetics[25]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 108 13 0 simundump kenz /kinetics/chain/kinetics[25]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 113 20 0 simundump kpool /kinetics/chain/kinetics[25]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 117 1 \ 0 simundump kenz /kinetics/chain/kinetics[25]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 114 10 0 simundump kreac /kinetics/chain/kinetics[25]/MAPK*/diff 0 0.101 0.001 "" \ white black 118 4 0 simundump group /kinetics/chain/kinetics[25]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 119 11 0 simundump kpool /kinetics/chain/kinetics[25]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 110 8 0 simundump kreac /kinetics/chain/kinetics[25]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 111 11 0 simundump kpool /kinetics/chain/kinetics[25]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 113 8 0 simundump kreac /kinetics/chain/kinetics[25]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 114 11 0 simundump kpool /kinetics/chain/kinetics[25]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 110 4 0 simundump kreac /kinetics/chain/kinetics[25]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 111 7 0 simundump kpool /kinetics/chain/kinetics[25]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 110 1 0 simundump kreac /kinetics/chain/kinetics[25]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 111 4 0 simundump kpool /kinetics/chain/kinetics[25]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 116 8 0 simundump kreac /kinetics/chain/kinetics[25]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 117 11 0 simundump kpool /kinetics/chain/kinetics[25]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 113 1 0 simundump kreac /kinetics/chain/kinetics[25]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 114 4 0 simundump kpool /kinetics/chain/kinetics[25]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 117 4 \ 0 simundump kenz /kinetics/chain/kinetics[25]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 112 3 \ 0 simundump kenz /kinetics/chain/kinetics[25]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 117 3 \ 0 simundump kreac /kinetics/chain/kinetics[25]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 118 7 0 simundump kpool /kinetics/chain/kinetics[25]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 113 4 0 simundump kreac /kinetics/chain/kinetics[25]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 114 7 0 simundump kpool /kinetics/chain/kinetics[25]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 109 6 0 simundump kenz /kinetics/chain/kinetics[25]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 112 6 0 simundump kenz /kinetics/chain/kinetics[25]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 115 6 0 simundump kreac /kinetics/chain/kinetics[25]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 110 9 0 simundump kpool /kinetics/chain/kinetics[25]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 109 5 0 simundump kenz /kinetics/chain/kinetics[25]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 112 5 0 simundump kenz /kinetics/chain/kinetics[25]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 115 5 0 simundump kreac /kinetics/chain/kinetics[25]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 110 8 0 simundump kpool /kinetics/chain/kinetics[25]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 109 2 0 simundump kenz /kinetics/chain/kinetics[25]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 110 3 0 simundump kenz /kinetics/chain/kinetics[25]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 115 3 0 simundump kreac /kinetics/chain/kinetics[25]/MKP-1/diff 0 0.101 0.001 "" \ white black 110 5 0 simundump kreac /kinetics/chain/kinetics[25]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 107 9 0 simundump kpool /kinetics/chain/kinetics[25]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 113 9 0 simundump kenz /kinetics/chain/kinetics[25]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 112 10 0 simundump kenz /kinetics/chain/kinetics[25]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 115 7 0 simundump kenz /kinetics/chain/kinetics[25]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 112 7 0 simundump kenz /kinetics/chain/kinetics[25]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 116 10 0 simundump kreac /kinetics/chain/kinetics[25]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 114 12 0 simundump group /kinetics/chain/kinetics[25]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 118.51 16.351 0 simundump kreac /kinetics/chain/kinetics[25]/Ras/dephosph-GEF 1 1 0 "" white \ blue 113.07 17.881 0 simundump kpool /kinetics/chain/kinetics[25]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 116.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[25]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 116 17 0 simundump kreac /kinetics/chain/kinetics[25]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 117.45 21.352 0 simundump kpool /kinetics/chain/kinetics[25]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 110.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[25]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 111.09 16.086 0 simundump kreac /kinetics/chain/kinetics[25]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 111.45 20.246 0 simundump kpool /kinetics/chain/kinetics[25]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 116.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[25]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 117.56 16.084 0 simundump kpool /kinetics/chain/kinetics[25]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 110.13 14.165 0 simundump kreac /kinetics/chain/kinetics[25]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 111.13 17.165 0 simundump kreac /kinetics/chain/kinetics[25]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 113.1 13.5 0 simundump kreac /kinetics/chain/kinetics[25]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 108.02 15.524 0 simundump kpool /kinetics/chain/kinetics[25]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 105.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[25]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 106.35 17.349 0 simundump kpool /kinetics/chain/kinetics[25]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 110.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[25]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 113.01 12.403 0 simundump kreac /kinetics/chain/kinetics[25]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 111.65 15.338 0 simundump kreac /kinetics/chain/kinetics[25]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 106.49 21.679 0 simundump kpool /kinetics/chain/kinetics[25]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 109.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[25]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 109.02 18.657 0 simundump kreac /kinetics/chain/kinetics[25]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 110.35 22.58 0 simundump group /kinetics/chain/kinetics[25]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 94 21 0 simundump kpool /kinetics/chain/kinetics[25]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 91 30 0 simundump kreac /kinetics/chain/kinetics[25]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 92 33 0 simundump kreac /kinetics/chain/kinetics[25]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 93.6 23.26 0 simundump kpool /kinetics/chain/kinetics[25]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 97.489 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[25]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 98.489 27.397 0 simundump kpool /kinetics/chain/kinetics[25]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 102 24 \ 0 simundump kreac /kinetics/chain/kinetics[25]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 103 27 0 simundump kreac /kinetics/chain/kinetics[25]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 94 30 0 simundump kpool /kinetics/chain/kinetics[25]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 98.999 \ 27.258 0 simundump kreac /kinetics/chain/kinetics[25]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 99.999 30.258 0 simundump kreac /kinetics/chain/kinetics[25]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 95.158 26.225 0 simundump kreac /kinetics/chain/kinetics[25]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 100 30 0 simundump kpool /kinetics/chain/kinetics[25]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 97 31 0 simundump kreac /kinetics/chain/kinetics[25]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 98 34 0 simundump kpool /kinetics/chain/kinetics[25]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 86 23 0 simundump kreac /kinetics/chain/kinetics[25]/Ca/diff 0 0.101 0.001 "" white \ black 87 26 0 simundump kreac /kinetics/chain/kinetics[25]/Ras-act-unphosph-raf 0 0 0 "" \ white black 108 8 0 simundump group /kinetics/chain/kinetics[25]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 97 19 0 simundump kpool /kinetics/chain/kinetics[25]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 93 17 0 simundump kreac /kinetics/chain/kinetics[25]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 94 20 0 simundump kpool /kinetics/chain/kinetics[25]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 93 9 0 simundump kenz /kinetics/chain/kinetics[25]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 94 10 0 simundump kreac /kinetics/chain/kinetics[25]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 94 12 0 simundump kpool /kinetics/chain/kinetics[25]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 97 12 0 simundump kreac /kinetics/chain/kinetics[25]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 96 7 0 simundump kpool /kinetics/chain/kinetics[25]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 92 5 0 simundump kpool /kinetics/chain/kinetics[25]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 92 \ 14 0 simundump kenz /kinetics/chain/kinetics[25]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 92 13 0 simundump kreac /kinetics/chain/kinetics[25]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 93 17 0 simundump kpool /kinetics/chain/kinetics[25]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 89 12 0 simundump kreac /kinetics/chain/kinetics[25]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 90 15 0 simundump kreac /kinetics/chain/kinetics[25]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 87 9 0 simundump kreac /kinetics/chain/kinetics[25]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 87 16 0 simundump kpool /kinetics/chain/kinetics[25]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 86 30 0 simundump kreac /kinetics/chain/kinetics[25]/Ca_diff 0 5 5 "" white black 86 \ 26 0 simundump group /kinetics/chain/kinetics[26] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 108 0 0 simundump group /kinetics/chain/kinetics[26]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 104.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[26]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 103.92 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[26]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 104.92 4.5108 0 simundump kreac /kinetics/chain/kinetics[26]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 103.92 -0.12295 0 simundump kreac /kinetics/chain/kinetics[26]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 105.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[26]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 104.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[26]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 105.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[26]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 105.22 6.529 0 simundump kreac /kinetics/chain/kinetics[26]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 106.22 9.529 0 simundump kpool /kinetics/chain/kinetics[26]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 106.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[26]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 107.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[26]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 108.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[26]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 109.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[26]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 104.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[26]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 107 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[26]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 108 1.9143 0 simundump kpool /kinetics/chain/kinetics[26]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 101.87 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[26]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 102.87 3.5971 0 simundump kpool /kinetics/chain/kinetics[26]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 105 11 0 simundump kreac /kinetics/chain/kinetics[26]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 106 14 0 simundump kpool /kinetics/chain/kinetics[26]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 112 -3 0 simundump kpool /kinetics/chain/kinetics[26]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 108 9 0 simundump kenz /kinetics/chain/kinetics[26]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 114 10 0 simundump kenz /kinetics/chain/kinetics[26]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 112 13 0 simundump kenz /kinetics/chain/kinetics[26]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 117 20 0 simundump kpool /kinetics/chain/kinetics[26]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 121 1 \ 0 simundump kenz /kinetics/chain/kinetics[26]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 118 10 0 simundump kreac /kinetics/chain/kinetics[26]/MAPK*/diff 0 0.101 0.001 "" \ white black 122 4 0 simundump group /kinetics/chain/kinetics[26]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 123 11 0 simundump kpool /kinetics/chain/kinetics[26]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 114 8 0 simundump kreac /kinetics/chain/kinetics[26]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 115 11 0 simundump kpool /kinetics/chain/kinetics[26]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 117 8 0 simundump kreac /kinetics/chain/kinetics[26]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 118 11 0 simundump kpool /kinetics/chain/kinetics[26]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 114 4 0 simundump kreac /kinetics/chain/kinetics[26]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 115 7 0 simundump kpool /kinetics/chain/kinetics[26]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 114 1 0 simundump kreac /kinetics/chain/kinetics[26]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 115 4 0 simundump kpool /kinetics/chain/kinetics[26]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 120 8 0 simundump kreac /kinetics/chain/kinetics[26]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 121 11 0 simundump kpool /kinetics/chain/kinetics[26]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 117 1 0 simundump kreac /kinetics/chain/kinetics[26]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 118 4 0 simundump kpool /kinetics/chain/kinetics[26]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 121 4 \ 0 simundump kenz /kinetics/chain/kinetics[26]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 116 3 \ 0 simundump kenz /kinetics/chain/kinetics[26]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 121 3 \ 0 simundump kreac /kinetics/chain/kinetics[26]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 122 7 0 simundump kpool /kinetics/chain/kinetics[26]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 117 4 0 simundump kreac /kinetics/chain/kinetics[26]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 118 7 0 simundump kpool /kinetics/chain/kinetics[26]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 113 6 0 simundump kenz /kinetics/chain/kinetics[26]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 116 6 0 simundump kenz /kinetics/chain/kinetics[26]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 119 6 0 simundump kreac /kinetics/chain/kinetics[26]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 114 9 0 simundump kpool /kinetics/chain/kinetics[26]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 113 5 0 simundump kenz /kinetics/chain/kinetics[26]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 116 5 0 simundump kenz /kinetics/chain/kinetics[26]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 119 5 0 simundump kreac /kinetics/chain/kinetics[26]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 114 8 0 simundump kpool /kinetics/chain/kinetics[26]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 113 2 0 simundump kenz /kinetics/chain/kinetics[26]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 114 3 0 simundump kenz /kinetics/chain/kinetics[26]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 119 3 0 simundump kreac /kinetics/chain/kinetics[26]/MKP-1/diff 0 0.101 0.001 "" \ white black 114 5 0 simundump kreac /kinetics/chain/kinetics[26]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 111 9 0 simundump kpool /kinetics/chain/kinetics[26]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 117 9 0 simundump kenz /kinetics/chain/kinetics[26]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 116 10 0 simundump kenz /kinetics/chain/kinetics[26]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 119 7 0 simundump kenz /kinetics/chain/kinetics[26]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 116 7 0 simundump kenz /kinetics/chain/kinetics[26]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 120 10 0 simundump kreac /kinetics/chain/kinetics[26]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 118 12 0 simundump group /kinetics/chain/kinetics[26]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 122.51 16.351 0 simundump kreac /kinetics/chain/kinetics[26]/Ras/dephosph-GEF 1 1 0 "" white \ blue 117.07 17.881 0 simundump kpool /kinetics/chain/kinetics[26]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 120.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[26]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 120 17 0 simundump kreac /kinetics/chain/kinetics[26]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 121.45 21.352 0 simundump kpool /kinetics/chain/kinetics[26]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 114.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[26]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 115.09 16.086 0 simundump kreac /kinetics/chain/kinetics[26]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 115.45 20.246 0 simundump kpool /kinetics/chain/kinetics[26]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 120.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[26]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 121.56 16.084 0 simundump kpool /kinetics/chain/kinetics[26]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 114.13 14.165 0 simundump kreac /kinetics/chain/kinetics[26]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 115.13 17.165 0 simundump kreac /kinetics/chain/kinetics[26]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 117.1 13.5 0 simundump kreac /kinetics/chain/kinetics[26]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 112.02 15.524 0 simundump kpool /kinetics/chain/kinetics[26]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 109.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[26]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 110.35 17.349 0 simundump kpool /kinetics/chain/kinetics[26]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 114.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[26]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 117.01 12.403 0 simundump kreac /kinetics/chain/kinetics[26]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 115.65 15.338 0 simundump kreac /kinetics/chain/kinetics[26]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 110.49 21.679 0 simundump kpool /kinetics/chain/kinetics[26]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 113.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[26]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 113.02 18.657 0 simundump kreac /kinetics/chain/kinetics[26]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 114.35 22.58 0 simundump group /kinetics/chain/kinetics[26]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 98 21 0 simundump kpool /kinetics/chain/kinetics[26]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 95 30 0 simundump kreac /kinetics/chain/kinetics[26]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 96 33 0 simundump kreac /kinetics/chain/kinetics[26]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 97.6 23.26 0 simundump kpool /kinetics/chain/kinetics[26]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 101.49 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[26]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 102.49 27.397 0 simundump kpool /kinetics/chain/kinetics[26]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 106 24 \ 0 simundump kreac /kinetics/chain/kinetics[26]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 107 27 0 simundump kreac /kinetics/chain/kinetics[26]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 98 30 0 simundump kpool /kinetics/chain/kinetics[26]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 103 27.258 0 simundump kreac /kinetics/chain/kinetics[26]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 104 30.258 0 simundump kreac /kinetics/chain/kinetics[26]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 99.158 26.225 0 simundump kreac /kinetics/chain/kinetics[26]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 104 30 0 simundump kpool /kinetics/chain/kinetics[26]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 101 31 0 simundump kreac /kinetics/chain/kinetics[26]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 102 34 0 simundump kpool /kinetics/chain/kinetics[26]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 90 23 0 simundump kreac /kinetics/chain/kinetics[26]/Ca/diff 0 0.101 0.001 "" white \ black 91 26 0 simundump kreac /kinetics/chain/kinetics[26]/Ras-act-unphosph-raf 0 0 0 "" \ white black 112 8 0 simundump group /kinetics/chain/kinetics[26]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 101 19 0 simundump kpool /kinetics/chain/kinetics[26]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 97 17 0 simundump kreac /kinetics/chain/kinetics[26]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 98 20 0 simundump kpool /kinetics/chain/kinetics[26]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 97 9 0 simundump kenz /kinetics/chain/kinetics[26]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 98 10 0 simundump kreac /kinetics/chain/kinetics[26]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 98 12 0 simundump kpool /kinetics/chain/kinetics[26]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 101 12 0 simundump kreac /kinetics/chain/kinetics[26]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 100 7 0 simundump kpool /kinetics/chain/kinetics[26]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 96 5 0 simundump kpool /kinetics/chain/kinetics[26]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 96 \ 14 0 simundump kenz /kinetics/chain/kinetics[26]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 96 13 0 simundump kreac /kinetics/chain/kinetics[26]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 97 17 0 simundump kpool /kinetics/chain/kinetics[26]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 93 12 0 simundump kreac /kinetics/chain/kinetics[26]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 94 15 0 simundump kreac /kinetics/chain/kinetics[26]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 91 9 0 simundump kreac /kinetics/chain/kinetics[26]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 91 16 0 simundump kpool /kinetics/chain/kinetics[26]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 90 30 0 simundump kreac /kinetics/chain/kinetics[26]/Ca_diff 0 5 5 "" white black 90 \ 26 0 simundump group /kinetics/chain/kinetics[27] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 112 0 0 simundump group /kinetics/chain/kinetics[27]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 108.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[27]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 107.92 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[27]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 108.92 4.5108 0 simundump kreac /kinetics/chain/kinetics[27]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 107.92 -0.12295 0 simundump kreac /kinetics/chain/kinetics[27]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 109.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[27]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 108.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[27]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 109.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[27]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 109.22 6.529 0 simundump kreac /kinetics/chain/kinetics[27]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 110.22 9.529 0 simundump kpool /kinetics/chain/kinetics[27]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 110.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[27]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 111.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[27]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 112.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[27]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 113.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[27]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 108.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[27]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 111 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[27]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 112 1.9143 0 simundump kpool /kinetics/chain/kinetics[27]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 105.87 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[27]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 106.87 3.5971 0 simundump kpool /kinetics/chain/kinetics[27]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 109 11 0 simundump kreac /kinetics/chain/kinetics[27]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 110 14 0 simundump kpool /kinetics/chain/kinetics[27]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 116 -3 0 simundump kpool /kinetics/chain/kinetics[27]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 112 9 0 simundump kenz /kinetics/chain/kinetics[27]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 118 10 0 simundump kenz /kinetics/chain/kinetics[27]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 116 13 0 simundump kenz /kinetics/chain/kinetics[27]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 121 20 0 simundump kpool /kinetics/chain/kinetics[27]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 125 1 \ 0 simundump kenz /kinetics/chain/kinetics[27]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 122 10 0 simundump kreac /kinetics/chain/kinetics[27]/MAPK*/diff 0 0.101 0.001 "" \ white black 126 4 0 simundump group /kinetics/chain/kinetics[27]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 127 11 0 simundump kpool /kinetics/chain/kinetics[27]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 118 8 0 simundump kreac /kinetics/chain/kinetics[27]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 119 11 0 simundump kpool /kinetics/chain/kinetics[27]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 121 8 0 simundump kreac /kinetics/chain/kinetics[27]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 122 11 0 simundump kpool /kinetics/chain/kinetics[27]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 118 4 0 simundump kreac /kinetics/chain/kinetics[27]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 119 7 0 simundump kpool /kinetics/chain/kinetics[27]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 118 1 0 simundump kreac /kinetics/chain/kinetics[27]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 119 4 0 simundump kpool /kinetics/chain/kinetics[27]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 124 8 0 simundump kreac /kinetics/chain/kinetics[27]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 125 11 0 simundump kpool /kinetics/chain/kinetics[27]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 121 1 0 simundump kreac /kinetics/chain/kinetics[27]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 122 4 0 simundump kpool /kinetics/chain/kinetics[27]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 125 4 \ 0 simundump kenz /kinetics/chain/kinetics[27]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 120 3 \ 0 simundump kenz /kinetics/chain/kinetics[27]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 125 3 \ 0 simundump kreac /kinetics/chain/kinetics[27]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 126 7 0 simundump kpool /kinetics/chain/kinetics[27]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 121 4 0 simundump kreac /kinetics/chain/kinetics[27]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 122 7 0 simundump kpool /kinetics/chain/kinetics[27]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 117 6 0 simundump kenz /kinetics/chain/kinetics[27]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 120 6 0 simundump kenz /kinetics/chain/kinetics[27]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 123 6 0 simundump kreac /kinetics/chain/kinetics[27]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 118 9 0 simundump kpool /kinetics/chain/kinetics[27]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 117 5 0 simundump kenz /kinetics/chain/kinetics[27]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 120 5 0 simundump kenz /kinetics/chain/kinetics[27]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 123 5 0 simundump kreac /kinetics/chain/kinetics[27]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 118 8 0 simundump kpool /kinetics/chain/kinetics[27]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 117 2 0 simundump kenz /kinetics/chain/kinetics[27]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 118 3 0 simundump kenz /kinetics/chain/kinetics[27]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 123 3 0 simundump kreac /kinetics/chain/kinetics[27]/MKP-1/diff 0 0.101 0.001 "" \ white black 118 5 0 simundump kreac /kinetics/chain/kinetics[27]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 115 9 0 simundump kpool /kinetics/chain/kinetics[27]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 121 9 0 simundump kenz /kinetics/chain/kinetics[27]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 120 10 0 simundump kenz /kinetics/chain/kinetics[27]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 123 7 0 simundump kenz /kinetics/chain/kinetics[27]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 120 7 0 simundump kenz /kinetics/chain/kinetics[27]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 124 10 0 simundump kreac /kinetics/chain/kinetics[27]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 122 12 0 simundump group /kinetics/chain/kinetics[27]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 126.51 16.351 0 simundump kreac /kinetics/chain/kinetics[27]/Ras/dephosph-GEF 1 1 0 "" white \ blue 121.07 17.881 0 simundump kpool /kinetics/chain/kinetics[27]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 124.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[27]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 124 17 0 simundump kreac /kinetics/chain/kinetics[27]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 125.45 21.352 0 simundump kpool /kinetics/chain/kinetics[27]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 118.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[27]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 119.09 16.086 0 simundump kreac /kinetics/chain/kinetics[27]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 119.45 20.246 0 simundump kpool /kinetics/chain/kinetics[27]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 124.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[27]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 125.56 16.084 0 simundump kpool /kinetics/chain/kinetics[27]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 118.13 14.165 0 simundump kreac /kinetics/chain/kinetics[27]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 119.13 17.165 0 simundump kreac /kinetics/chain/kinetics[27]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 121.1 13.5 0 simundump kreac /kinetics/chain/kinetics[27]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 116.02 15.524 0 simundump kpool /kinetics/chain/kinetics[27]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 113.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[27]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 114.35 17.349 0 simundump kpool /kinetics/chain/kinetics[27]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 118.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[27]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 121.01 12.403 0 simundump kreac /kinetics/chain/kinetics[27]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 119.65 15.338 0 simundump kreac /kinetics/chain/kinetics[27]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 114.49 21.679 0 simundump kpool /kinetics/chain/kinetics[27]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 117.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[27]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 117.02 18.657 0 simundump kreac /kinetics/chain/kinetics[27]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 118.35 22.58 0 simundump group /kinetics/chain/kinetics[27]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 102 21 0 simundump kpool /kinetics/chain/kinetics[27]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 99 30 0 simundump kreac /kinetics/chain/kinetics[27]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 100 33 0 simundump kreac /kinetics/chain/kinetics[27]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 101.6 23.26 0 simundump kpool /kinetics/chain/kinetics[27]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 105.49 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[27]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 106.49 27.397 0 simundump kpool /kinetics/chain/kinetics[27]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 110 24 \ 0 simundump kreac /kinetics/chain/kinetics[27]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 111 27 0 simundump kreac /kinetics/chain/kinetics[27]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 102 30 0 simundump kpool /kinetics/chain/kinetics[27]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 107 27.258 0 simundump kreac /kinetics/chain/kinetics[27]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 108 30.258 0 simundump kreac /kinetics/chain/kinetics[27]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 103.16 26.225 0 simundump kreac /kinetics/chain/kinetics[27]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 108 30 0 simundump kpool /kinetics/chain/kinetics[27]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 105 31 0 simundump kreac /kinetics/chain/kinetics[27]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 106 34 0 simundump kpool /kinetics/chain/kinetics[27]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 94 23 0 simundump kreac /kinetics/chain/kinetics[27]/Ca/diff 0 0.101 0.001 "" white \ black 95 26 0 simundump kreac /kinetics/chain/kinetics[27]/Ras-act-unphosph-raf 0 0 0 "" \ white black 116 8 0 simundump group /kinetics/chain/kinetics[27]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 105 19 0 simundump kpool /kinetics/chain/kinetics[27]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 101 17 0 simundump kreac /kinetics/chain/kinetics[27]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 102 20 0 simundump kpool /kinetics/chain/kinetics[27]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 101 9 0 simundump kenz /kinetics/chain/kinetics[27]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 102 10 0 simundump kreac /kinetics/chain/kinetics[27]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 102 12 0 simundump kpool /kinetics/chain/kinetics[27]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 105 12 0 simundump kreac /kinetics/chain/kinetics[27]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 104 7 0 simundump kpool /kinetics/chain/kinetics[27]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 100 5 0 simundump kpool /kinetics/chain/kinetics[27]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 100 \ 14 0 simundump kenz /kinetics/chain/kinetics[27]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 100 13 0 simundump kreac /kinetics/chain/kinetics[27]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 101 17 0 simundump kpool /kinetics/chain/kinetics[27]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 97 12 0 simundump kreac /kinetics/chain/kinetics[27]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 98 15 0 simundump kreac /kinetics/chain/kinetics[27]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 95 9 0 simundump kreac /kinetics/chain/kinetics[27]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 95 16 0 simundump kpool /kinetics/chain/kinetics[27]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 94 30 0 simundump kreac /kinetics/chain/kinetics[27]/Ca_diff 0 5 5 "" white black 94 \ 26 0 simundump group /kinetics/chain/kinetics[28] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 116 0 0 simundump group /kinetics/chain/kinetics[28]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 112.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[28]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 111.92 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[28]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 112.92 4.5108 0 simundump kreac /kinetics/chain/kinetics[28]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 111.92 -0.12295 0 simundump kreac /kinetics/chain/kinetics[28]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 113.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[28]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 112.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[28]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 113.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[28]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 113.22 6.529 0 simundump kreac /kinetics/chain/kinetics[28]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 114.22 9.529 0 simundump kpool /kinetics/chain/kinetics[28]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 114.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[28]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 115.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[28]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 116.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[28]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 117.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[28]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 112.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[28]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 115 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[28]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 116 1.9143 0 simundump kpool /kinetics/chain/kinetics[28]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 109.87 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[28]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 110.87 3.5971 0 simundump kpool /kinetics/chain/kinetics[28]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 113 11 0 simundump kreac /kinetics/chain/kinetics[28]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 114 14 0 simundump kpool /kinetics/chain/kinetics[28]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 120 -3 0 simundump kpool /kinetics/chain/kinetics[28]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 116 9 0 simundump kenz /kinetics/chain/kinetics[28]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 122 10 0 simundump kenz /kinetics/chain/kinetics[28]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 120 13 0 simundump kenz /kinetics/chain/kinetics[28]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 125 20 0 simundump kpool /kinetics/chain/kinetics[28]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 129 1 \ 0 simundump kenz /kinetics/chain/kinetics[28]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 126 10 0 simundump kreac /kinetics/chain/kinetics[28]/MAPK*/diff 0 0.101 0.001 "" \ white black 130 4 0 simundump group /kinetics/chain/kinetics[28]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 131 11 0 simundump kpool /kinetics/chain/kinetics[28]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 122 8 0 simundump kreac /kinetics/chain/kinetics[28]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 123 11 0 simundump kpool /kinetics/chain/kinetics[28]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 125 8 0 simundump kreac /kinetics/chain/kinetics[28]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 126 11 0 simundump kpool /kinetics/chain/kinetics[28]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 122 4 0 simundump kreac /kinetics/chain/kinetics[28]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 123 7 0 simundump kpool /kinetics/chain/kinetics[28]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 122 1 0 simundump kreac /kinetics/chain/kinetics[28]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 123 4 0 simundump kpool /kinetics/chain/kinetics[28]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 128 8 0 simundump kreac /kinetics/chain/kinetics[28]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 129 11 0 simundump kpool /kinetics/chain/kinetics[28]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 125 1 0 simundump kreac /kinetics/chain/kinetics[28]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 126 4 0 simundump kpool /kinetics/chain/kinetics[28]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 129 4 \ 0 simundump kenz /kinetics/chain/kinetics[28]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 124 3 \ 0 simundump kenz /kinetics/chain/kinetics[28]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 129 3 \ 0 simundump kreac /kinetics/chain/kinetics[28]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 130 7 0 simundump kpool /kinetics/chain/kinetics[28]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 125 4 0 simundump kreac /kinetics/chain/kinetics[28]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 126 7 0 simundump kpool /kinetics/chain/kinetics[28]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 121 6 0 simundump kenz /kinetics/chain/kinetics[28]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 124 6 0 simundump kenz /kinetics/chain/kinetics[28]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 127 6 0 simundump kreac /kinetics/chain/kinetics[28]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 122 9 0 simundump kpool /kinetics/chain/kinetics[28]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 121 5 0 simundump kenz /kinetics/chain/kinetics[28]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 124 5 0 simundump kenz /kinetics/chain/kinetics[28]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 127 5 0 simundump kreac /kinetics/chain/kinetics[28]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 122 8 0 simundump kpool /kinetics/chain/kinetics[28]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 121 2 0 simundump kenz /kinetics/chain/kinetics[28]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 122 3 0 simundump kenz /kinetics/chain/kinetics[28]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 127 3 0 simundump kreac /kinetics/chain/kinetics[28]/MKP-1/diff 0 0.101 0.001 "" \ white black 122 5 0 simundump kreac /kinetics/chain/kinetics[28]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 119 9 0 simundump kpool /kinetics/chain/kinetics[28]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 125 9 0 simundump kenz /kinetics/chain/kinetics[28]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 124 10 0 simundump kenz /kinetics/chain/kinetics[28]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 127 7 0 simundump kenz /kinetics/chain/kinetics[28]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 124 7 0 simundump kenz /kinetics/chain/kinetics[28]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 128 10 0 simundump kreac /kinetics/chain/kinetics[28]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 126 12 0 simundump group /kinetics/chain/kinetics[28]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 130.51 16.351 0 simundump kreac /kinetics/chain/kinetics[28]/Ras/dephosph-GEF 1 1 0 "" white \ blue 125.07 17.881 0 simundump kpool /kinetics/chain/kinetics[28]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 128.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[28]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 128 17 0 simundump kreac /kinetics/chain/kinetics[28]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 129.45 21.352 0 simundump kpool /kinetics/chain/kinetics[28]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 122.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[28]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 123.09 16.086 0 simundump kreac /kinetics/chain/kinetics[28]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 123.45 20.246 0 simundump kpool /kinetics/chain/kinetics[28]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 128.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[28]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 129.56 16.084 0 simundump kpool /kinetics/chain/kinetics[28]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 122.13 14.165 0 simundump kreac /kinetics/chain/kinetics[28]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 123.13 17.165 0 simundump kreac /kinetics/chain/kinetics[28]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 125.1 13.5 0 simundump kreac /kinetics/chain/kinetics[28]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 120.02 15.524 0 simundump kpool /kinetics/chain/kinetics[28]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 117.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[28]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 118.35 17.349 0 simundump kpool /kinetics/chain/kinetics[28]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 122.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[28]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 125.01 12.403 0 simundump kreac /kinetics/chain/kinetics[28]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 123.65 15.338 0 simundump kreac /kinetics/chain/kinetics[28]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 118.49 21.679 0 simundump kpool /kinetics/chain/kinetics[28]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 121.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[28]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 121.02 18.657 0 simundump kreac /kinetics/chain/kinetics[28]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 122.35 22.58 0 simundump group /kinetics/chain/kinetics[28]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 106 21 0 simundump kpool /kinetics/chain/kinetics[28]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 103 30 0 simundump kreac /kinetics/chain/kinetics[28]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 104 33 0 simundump kreac /kinetics/chain/kinetics[28]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 105.6 23.26 0 simundump kpool /kinetics/chain/kinetics[28]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 109.49 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[28]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 110.49 27.397 0 simundump kpool /kinetics/chain/kinetics[28]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 114 24 \ 0 simundump kreac /kinetics/chain/kinetics[28]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 115 27 0 simundump kreac /kinetics/chain/kinetics[28]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 106 30 0 simundump kpool /kinetics/chain/kinetics[28]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 111 27.258 0 simundump kreac /kinetics/chain/kinetics[28]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 112 30.258 0 simundump kreac /kinetics/chain/kinetics[28]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 107.16 26.225 0 simundump kreac /kinetics/chain/kinetics[28]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 112 30 0 simundump kpool /kinetics/chain/kinetics[28]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 109 31 0 simundump kreac /kinetics/chain/kinetics[28]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 110 34 0 simundump kpool /kinetics/chain/kinetics[28]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 98 23 0 simundump kreac /kinetics/chain/kinetics[28]/Ca/diff 0 0.101 0.001 "" white \ black 99 26 0 simundump kreac /kinetics/chain/kinetics[28]/Ras-act-unphosph-raf 0 0 0 "" \ white black 120 8 0 simundump group /kinetics/chain/kinetics[28]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 109 19 0 simundump kpool /kinetics/chain/kinetics[28]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 105 17 0 simundump kreac /kinetics/chain/kinetics[28]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 106 20 0 simundump kpool /kinetics/chain/kinetics[28]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 105 9 0 simundump kenz /kinetics/chain/kinetics[28]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 106 10 0 simundump kreac /kinetics/chain/kinetics[28]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 106 12 0 simundump kpool /kinetics/chain/kinetics[28]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 109 12 0 simundump kreac /kinetics/chain/kinetics[28]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 108 7 0 simundump kpool /kinetics/chain/kinetics[28]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 104 5 0 simundump kpool /kinetics/chain/kinetics[28]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 104 \ 14 0 simundump kenz /kinetics/chain/kinetics[28]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 104 13 0 simundump kreac /kinetics/chain/kinetics[28]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 105 17 0 simundump kpool /kinetics/chain/kinetics[28]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 101 12 0 simundump kreac /kinetics/chain/kinetics[28]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 102 15 0 simundump kreac /kinetics/chain/kinetics[28]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 99 9 0 simundump kreac /kinetics/chain/kinetics[28]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 99 16 0 simundump kpool /kinetics/chain/kinetics[28]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 98 30 0 simundump kreac /kinetics/chain/kinetics[28]/Ca_diff 0 5 5 "" white black 98 \ 26 0 simundump group /kinetics/chain/kinetics[29] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 120 0 0 simundump group /kinetics/chain/kinetics[29]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 116.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[29]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 115.92 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[29]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 116.92 4.5108 0 simundump kreac /kinetics/chain/kinetics[29]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 115.92 -0.12295 0 simundump kreac /kinetics/chain/kinetics[29]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 117.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[29]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 116.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[29]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 117.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[29]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 117.22 6.529 0 simundump kreac /kinetics/chain/kinetics[29]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 118.22 9.529 0 simundump kpool /kinetics/chain/kinetics[29]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 118.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[29]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 119.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[29]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 120.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[29]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 121.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[29]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 116.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[29]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 119 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[29]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 120 1.9143 0 simundump kpool /kinetics/chain/kinetics[29]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 113.87 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[29]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 114.87 3.5971 0 simundump kpool /kinetics/chain/kinetics[29]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 117 11 0 simundump kreac /kinetics/chain/kinetics[29]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 118 14 0 simundump kpool /kinetics/chain/kinetics[29]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 124 -3 0 simundump kpool /kinetics/chain/kinetics[29]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 120 9 0 simundump kenz /kinetics/chain/kinetics[29]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 126 10 0 simundump kenz /kinetics/chain/kinetics[29]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 124 13 0 simundump kenz /kinetics/chain/kinetics[29]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 129 20 0 simundump kpool /kinetics/chain/kinetics[29]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 133 1 \ 0 simundump kenz /kinetics/chain/kinetics[29]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 130 10 0 simundump kreac /kinetics/chain/kinetics[29]/MAPK*/diff 0 0.101 0.001 "" \ white black 134 4 0 simundump group /kinetics/chain/kinetics[29]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 135 11 0 simundump kpool /kinetics/chain/kinetics[29]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 126 8 0 simundump kreac /kinetics/chain/kinetics[29]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 127 11 0 simundump kpool /kinetics/chain/kinetics[29]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 129 8 0 simundump kreac /kinetics/chain/kinetics[29]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 130 11 0 simundump kpool /kinetics/chain/kinetics[29]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 126 4 0 simundump kreac /kinetics/chain/kinetics[29]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 127 7 0 simundump kpool /kinetics/chain/kinetics[29]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 126 1 0 simundump kreac /kinetics/chain/kinetics[29]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 127 4 0 simundump kpool /kinetics/chain/kinetics[29]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 132 8 0 simundump kreac /kinetics/chain/kinetics[29]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 133 11 0 simundump kpool /kinetics/chain/kinetics[29]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 129 1 0 simundump kreac /kinetics/chain/kinetics[29]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 130 4 0 simundump kpool /kinetics/chain/kinetics[29]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 133 4 \ 0 simundump kenz /kinetics/chain/kinetics[29]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 128 3 \ 0 simundump kenz /kinetics/chain/kinetics[29]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 133 3 \ 0 simundump kreac /kinetics/chain/kinetics[29]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 134 7 0 simundump kpool /kinetics/chain/kinetics[29]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 129 4 0 simundump kreac /kinetics/chain/kinetics[29]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 130 7 0 simundump kpool /kinetics/chain/kinetics[29]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 125 6 0 simundump kenz /kinetics/chain/kinetics[29]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 128 6 0 simundump kenz /kinetics/chain/kinetics[29]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 131 6 0 simundump kreac /kinetics/chain/kinetics[29]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 126 9 0 simundump kpool /kinetics/chain/kinetics[29]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 125 5 0 simundump kenz /kinetics/chain/kinetics[29]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 128 5 0 simundump kenz /kinetics/chain/kinetics[29]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 131 5 0 simundump kreac /kinetics/chain/kinetics[29]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 126 8 0 simundump kpool /kinetics/chain/kinetics[29]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 125 2 0 simundump kenz /kinetics/chain/kinetics[29]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 126 3 0 simundump kenz /kinetics/chain/kinetics[29]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 131 3 0 simundump kreac /kinetics/chain/kinetics[29]/MKP-1/diff 0 0.101 0.001 "" \ white black 126 5 0 simundump kreac /kinetics/chain/kinetics[29]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 123 9 0 simundump kpool /kinetics/chain/kinetics[29]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 129 9 0 simundump kenz /kinetics/chain/kinetics[29]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 128 10 0 simundump kenz /kinetics/chain/kinetics[29]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 131 7 0 simundump kenz /kinetics/chain/kinetics[29]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 128 7 0 simundump kenz /kinetics/chain/kinetics[29]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 132 10 0 simundump kreac /kinetics/chain/kinetics[29]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 130 12 0 simundump group /kinetics/chain/kinetics[29]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 134.51 16.351 0 simundump kreac /kinetics/chain/kinetics[29]/Ras/dephosph-GEF 1 1 0 "" white \ blue 129.07 17.881 0 simundump kpool /kinetics/chain/kinetics[29]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 132.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[29]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 132 17 0 simundump kreac /kinetics/chain/kinetics[29]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 133.45 21.352 0 simundump kpool /kinetics/chain/kinetics[29]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 126.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[29]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 127.09 16.086 0 simundump kreac /kinetics/chain/kinetics[29]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 127.45 20.246 0 simundump kpool /kinetics/chain/kinetics[29]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 132.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[29]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 133.56 16.084 0 simundump kpool /kinetics/chain/kinetics[29]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 126.13 14.165 0 simundump kreac /kinetics/chain/kinetics[29]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 127.13 17.165 0 simundump kreac /kinetics/chain/kinetics[29]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 129.1 13.5 0 simundump kreac /kinetics/chain/kinetics[29]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 124.02 15.524 0 simundump kpool /kinetics/chain/kinetics[29]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 121.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[29]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 122.35 17.349 0 simundump kpool /kinetics/chain/kinetics[29]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 126.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[29]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 129.01 12.403 0 simundump kreac /kinetics/chain/kinetics[29]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 127.65 15.338 0 simundump kreac /kinetics/chain/kinetics[29]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 122.49 21.679 0 simundump kpool /kinetics/chain/kinetics[29]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 125.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[29]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 125.02 18.657 0 simundump kreac /kinetics/chain/kinetics[29]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 126.35 22.58 0 simundump group /kinetics/chain/kinetics[29]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 110 21 0 simundump kpool /kinetics/chain/kinetics[29]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 107 30 0 simundump kreac /kinetics/chain/kinetics[29]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 108 33 0 simundump kreac /kinetics/chain/kinetics[29]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 109.6 23.26 0 simundump kpool /kinetics/chain/kinetics[29]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 113.49 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[29]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 114.49 27.397 0 simundump kpool /kinetics/chain/kinetics[29]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 118 24 \ 0 simundump kreac /kinetics/chain/kinetics[29]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 119 27 0 simundump kreac /kinetics/chain/kinetics[29]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 110 30 0 simundump kpool /kinetics/chain/kinetics[29]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 115 27.258 0 simundump kreac /kinetics/chain/kinetics[29]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 116 30.258 0 simundump kreac /kinetics/chain/kinetics[29]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 111.16 26.225 0 simundump kreac /kinetics/chain/kinetics[29]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 116 30 0 simundump kpool /kinetics/chain/kinetics[29]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 113 31 0 simundump kreac /kinetics/chain/kinetics[29]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 114 34 0 simundump kpool /kinetics/chain/kinetics[29]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 102 23 0 simundump kreac /kinetics/chain/kinetics[29]/Ca/diff 0 0.101 0.001 "" white \ black 103 26 0 simundump kreac /kinetics/chain/kinetics[29]/Ras-act-unphosph-raf 0 0 0 "" \ white black 124 8 0 simundump group /kinetics/chain/kinetics[29]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 113 19 0 simundump kpool /kinetics/chain/kinetics[29]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 109 17 0 simundump kreac /kinetics/chain/kinetics[29]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 110 20 0 simundump kpool /kinetics/chain/kinetics[29]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 109 9 0 simundump kenz /kinetics/chain/kinetics[29]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 110 10 0 simundump kreac /kinetics/chain/kinetics[29]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 110 12 0 simundump kpool /kinetics/chain/kinetics[29]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 113 12 0 simundump kreac /kinetics/chain/kinetics[29]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 112 7 0 simundump kpool /kinetics/chain/kinetics[29]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 108 5 0 simundump kpool /kinetics/chain/kinetics[29]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 108 \ 14 0 simundump kenz /kinetics/chain/kinetics[29]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 108 13 0 simundump kreac /kinetics/chain/kinetics[29]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 109 17 0 simundump kpool /kinetics/chain/kinetics[29]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 105 12 0 simundump kreac /kinetics/chain/kinetics[29]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 106 15 0 simundump kreac /kinetics/chain/kinetics[29]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 103 9 0 simundump kreac /kinetics/chain/kinetics[29]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 103 16 0 simundump kpool /kinetics/chain/kinetics[29]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 102 30 0 simundump kreac /kinetics/chain/kinetics[29]/Ca_diff 0 5 5 "" white black 102 \ 26 0 simundump group /kinetics/chain/kinetics[30] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 124 0 0 simundump group /kinetics/chain/kinetics[30]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 120.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[30]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 119.92 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[30]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 120.92 4.5108 0 simundump kreac /kinetics/chain/kinetics[30]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 119.92 -0.12295 0 simundump kreac /kinetics/chain/kinetics[30]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 121.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[30]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 120.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[30]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 121.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[30]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 121.22 6.529 0 simundump kreac /kinetics/chain/kinetics[30]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 122.22 9.529 0 simundump kpool /kinetics/chain/kinetics[30]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 122.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[30]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 123.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[30]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 124.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[30]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 125.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[30]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 120.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[30]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 123 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[30]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 124 1.9143 0 simundump kpool /kinetics/chain/kinetics[30]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 117.87 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[30]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 118.87 3.5971 0 simundump kpool /kinetics/chain/kinetics[30]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 121 11 0 simundump kreac /kinetics/chain/kinetics[30]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 122 14 0 simundump kpool /kinetics/chain/kinetics[30]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 128 -3 0 simundump kpool /kinetics/chain/kinetics[30]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 124 9 0 simundump kenz /kinetics/chain/kinetics[30]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 130 10 0 simundump kenz /kinetics/chain/kinetics[30]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 128 13 0 simundump kenz /kinetics/chain/kinetics[30]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 133 20 0 simundump kpool /kinetics/chain/kinetics[30]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 137 1 \ 0 simundump kenz /kinetics/chain/kinetics[30]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 134 10 0 simundump kreac /kinetics/chain/kinetics[30]/MAPK*/diff 0 0.101 0.001 "" \ white black 138 4 0 simundump group /kinetics/chain/kinetics[30]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 139 11 0 simundump kpool /kinetics/chain/kinetics[30]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 130 8 0 simundump kreac /kinetics/chain/kinetics[30]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 131 11 0 simundump kpool /kinetics/chain/kinetics[30]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 133 8 0 simundump kreac /kinetics/chain/kinetics[30]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 134 11 0 simundump kpool /kinetics/chain/kinetics[30]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 130 4 0 simundump kreac /kinetics/chain/kinetics[30]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 131 7 0 simundump kpool /kinetics/chain/kinetics[30]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 130 1 0 simundump kreac /kinetics/chain/kinetics[30]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 131 4 0 simundump kpool /kinetics/chain/kinetics[30]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 136 8 0 simundump kreac /kinetics/chain/kinetics[30]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 137 11 0 simundump kpool /kinetics/chain/kinetics[30]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 133 1 0 simundump kreac /kinetics/chain/kinetics[30]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 134 4 0 simundump kpool /kinetics/chain/kinetics[30]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 137 4 \ 0 simundump kenz /kinetics/chain/kinetics[30]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 132 3 \ 0 simundump kenz /kinetics/chain/kinetics[30]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 137 3 \ 0 simundump kreac /kinetics/chain/kinetics[30]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 138 7 0 simundump kpool /kinetics/chain/kinetics[30]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 133 4 0 simundump kreac /kinetics/chain/kinetics[30]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 134 7 0 simundump kpool /kinetics/chain/kinetics[30]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 129 6 0 simundump kenz /kinetics/chain/kinetics[30]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 132 6 0 simundump kenz /kinetics/chain/kinetics[30]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 135 6 0 simundump kreac /kinetics/chain/kinetics[30]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 130 9 0 simundump kpool /kinetics/chain/kinetics[30]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 129 5 0 simundump kenz /kinetics/chain/kinetics[30]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 132 5 0 simundump kenz /kinetics/chain/kinetics[30]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 135 5 0 simundump kreac /kinetics/chain/kinetics[30]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 130 8 0 simundump kpool /kinetics/chain/kinetics[30]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 129 2 0 simundump kenz /kinetics/chain/kinetics[30]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 130 3 0 simundump kenz /kinetics/chain/kinetics[30]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 135 3 0 simundump kreac /kinetics/chain/kinetics[30]/MKP-1/diff 0 0.101 0.001 "" \ white black 130 5 0 simundump kreac /kinetics/chain/kinetics[30]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 127 9 0 simundump kpool /kinetics/chain/kinetics[30]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 133 9 0 simundump kenz /kinetics/chain/kinetics[30]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 132 10 0 simundump kenz /kinetics/chain/kinetics[30]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 135 7 0 simundump kenz /kinetics/chain/kinetics[30]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 132 7 0 simundump kenz /kinetics/chain/kinetics[30]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 136 10 0 simundump kreac /kinetics/chain/kinetics[30]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 134 12 0 simundump group /kinetics/chain/kinetics[30]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 138.51 16.351 0 simundump kreac /kinetics/chain/kinetics[30]/Ras/dephosph-GEF 1 1 0 "" white \ blue 133.07 17.881 0 simundump kpool /kinetics/chain/kinetics[30]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 136.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[30]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 136 17 0 simundump kreac /kinetics/chain/kinetics[30]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 137.45 21.352 0 simundump kpool /kinetics/chain/kinetics[30]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 130.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[30]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 131.09 16.086 0 simundump kreac /kinetics/chain/kinetics[30]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 131.45 20.246 0 simundump kpool /kinetics/chain/kinetics[30]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 136.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[30]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 137.56 16.084 0 simundump kpool /kinetics/chain/kinetics[30]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 130.13 14.165 0 simundump kreac /kinetics/chain/kinetics[30]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 131.13 17.165 0 simundump kreac /kinetics/chain/kinetics[30]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 133.1 13.5 0 simundump kreac /kinetics/chain/kinetics[30]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 128.02 15.524 0 simundump kpool /kinetics/chain/kinetics[30]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 125.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[30]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 126.35 17.349 0 simundump kpool /kinetics/chain/kinetics[30]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 130.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[30]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 133.01 12.403 0 simundump kreac /kinetics/chain/kinetics[30]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 131.65 15.338 0 simundump kreac /kinetics/chain/kinetics[30]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 126.49 21.679 0 simundump kpool /kinetics/chain/kinetics[30]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 129.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[30]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 129.02 18.657 0 simundump kreac /kinetics/chain/kinetics[30]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 130.35 22.58 0 simundump group /kinetics/chain/kinetics[30]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 114 21 0 simundump kpool /kinetics/chain/kinetics[30]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 111 30 0 simundump kreac /kinetics/chain/kinetics[30]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 112 33 0 simundump kreac /kinetics/chain/kinetics[30]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 113.6 23.26 0 simundump kpool /kinetics/chain/kinetics[30]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 117.49 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[30]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 118.49 27.397 0 simundump kpool /kinetics/chain/kinetics[30]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 122 24 \ 0 simundump kreac /kinetics/chain/kinetics[30]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 123 27 0 simundump kreac /kinetics/chain/kinetics[30]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 114 30 0 simundump kpool /kinetics/chain/kinetics[30]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 119 27.258 0 simundump kreac /kinetics/chain/kinetics[30]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 120 30.258 0 simundump kreac /kinetics/chain/kinetics[30]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 115.16 26.225 0 simundump kreac /kinetics/chain/kinetics[30]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 120 30 0 simundump kpool /kinetics/chain/kinetics[30]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 117 31 0 simundump kreac /kinetics/chain/kinetics[30]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 118 34 0 simundump kpool /kinetics/chain/kinetics[30]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 106 23 0 simundump kreac /kinetics/chain/kinetics[30]/Ca/diff 0 0.101 0.001 "" white \ black 107 26 0 simundump kreac /kinetics/chain/kinetics[30]/Ras-act-unphosph-raf 0 0 0 "" \ white black 128 8 0 simundump group /kinetics/chain/kinetics[30]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 117 19 0 simundump kpool /kinetics/chain/kinetics[30]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 113 17 0 simundump kreac /kinetics/chain/kinetics[30]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 114 20 0 simundump kpool /kinetics/chain/kinetics[30]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 113 9 0 simundump kenz /kinetics/chain/kinetics[30]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 114 10 0 simundump kreac /kinetics/chain/kinetics[30]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 114 12 0 simundump kpool /kinetics/chain/kinetics[30]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 117 12 0 simundump kreac /kinetics/chain/kinetics[30]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 116 7 0 simundump kpool /kinetics/chain/kinetics[30]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 112 5 0 simundump kpool /kinetics/chain/kinetics[30]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 112 \ 14 0 simundump kenz /kinetics/chain/kinetics[30]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 112 13 0 simundump kreac /kinetics/chain/kinetics[30]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 113 17 0 simundump kpool /kinetics/chain/kinetics[30]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 109 12 0 simundump kreac /kinetics/chain/kinetics[30]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 110 15 0 simundump kreac /kinetics/chain/kinetics[30]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 107 9 0 simundump kreac /kinetics/chain/kinetics[30]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 107 16 0 simundump kpool /kinetics/chain/kinetics[30]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 106 30 0 simundump kreac /kinetics/chain/kinetics[30]/Ca_diff 0 5 5 "" white black 106 \ 26 0 simundump group /kinetics/chain/kinetics[31] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 128 0 0 simundump group /kinetics/chain/kinetics[31]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 124.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[31]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 123.92 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[31]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 124.92 4.5108 0 simundump kreac /kinetics/chain/kinetics[31]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 123.92 -0.12295 0 simundump kreac /kinetics/chain/kinetics[31]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 125.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[31]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 124.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[31]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 125.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[31]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 125.22 6.529 0 simundump kreac /kinetics/chain/kinetics[31]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 126.22 9.529 0 simundump kpool /kinetics/chain/kinetics[31]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 126.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[31]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 127.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[31]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 128.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[31]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 129.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[31]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 124.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[31]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 127 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[31]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 128 1.9143 0 simundump kpool /kinetics/chain/kinetics[31]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 121.87 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[31]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 122.87 3.5971 0 simundump kpool /kinetics/chain/kinetics[31]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 125 11 0 simundump kreac /kinetics/chain/kinetics[31]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 126 14 0 simundump kpool /kinetics/chain/kinetics[31]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 132 -3 0 simundump kpool /kinetics/chain/kinetics[31]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 128 9 0 simundump kenz /kinetics/chain/kinetics[31]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 134 10 0 simundump kenz /kinetics/chain/kinetics[31]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 132 13 0 simundump kenz /kinetics/chain/kinetics[31]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 137 20 0 simundump kpool /kinetics/chain/kinetics[31]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 141 1 \ 0 simundump kenz /kinetics/chain/kinetics[31]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 138 10 0 simundump kreac /kinetics/chain/kinetics[31]/MAPK*/diff 0 0.101 0.001 "" \ white black 142 4 0 simundump group /kinetics/chain/kinetics[31]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 143 11 0 simundump kpool /kinetics/chain/kinetics[31]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 134 8 0 simundump kreac /kinetics/chain/kinetics[31]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 135 11 0 simundump kpool /kinetics/chain/kinetics[31]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 137 8 0 simundump kreac /kinetics/chain/kinetics[31]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 138 11 0 simundump kpool /kinetics/chain/kinetics[31]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 134 4 0 simundump kreac /kinetics/chain/kinetics[31]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 135 7 0 simundump kpool /kinetics/chain/kinetics[31]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 134 1 0 simundump kreac /kinetics/chain/kinetics[31]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 135 4 0 simundump kpool /kinetics/chain/kinetics[31]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 140 8 0 simundump kreac /kinetics/chain/kinetics[31]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 141 11 0 simundump kpool /kinetics/chain/kinetics[31]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 137 1 0 simundump kreac /kinetics/chain/kinetics[31]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 138 4 0 simundump kpool /kinetics/chain/kinetics[31]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 141 4 \ 0 simundump kenz /kinetics/chain/kinetics[31]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 136 3 \ 0 simundump kenz /kinetics/chain/kinetics[31]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 141 3 \ 0 simundump kreac /kinetics/chain/kinetics[31]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 142 7 0 simundump kpool /kinetics/chain/kinetics[31]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 137 4 0 simundump kreac /kinetics/chain/kinetics[31]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 138 7 0 simundump kpool /kinetics/chain/kinetics[31]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 133 6 0 simundump kenz /kinetics/chain/kinetics[31]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 136 6 0 simundump kenz /kinetics/chain/kinetics[31]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 139 6 0 simundump kreac /kinetics/chain/kinetics[31]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 134 9 0 simundump kpool /kinetics/chain/kinetics[31]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 133 5 0 simundump kenz /kinetics/chain/kinetics[31]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 136 5 0 simundump kenz /kinetics/chain/kinetics[31]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 139 5 0 simundump kreac /kinetics/chain/kinetics[31]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 134 8 0 simundump kpool /kinetics/chain/kinetics[31]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 133 2 0 simundump kenz /kinetics/chain/kinetics[31]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 134 3 0 simundump kenz /kinetics/chain/kinetics[31]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 139 3 0 simundump kreac /kinetics/chain/kinetics[31]/MKP-1/diff 0 0.101 0.001 "" \ white black 134 5 0 simundump kreac /kinetics/chain/kinetics[31]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 131 9 0 simundump kpool /kinetics/chain/kinetics[31]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 137 9 0 simundump kenz /kinetics/chain/kinetics[31]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 136 10 0 simundump kenz /kinetics/chain/kinetics[31]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 139 7 0 simundump kenz /kinetics/chain/kinetics[31]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 136 7 0 simundump kenz /kinetics/chain/kinetics[31]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 140 10 0 simundump kreac /kinetics/chain/kinetics[31]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 138 12 0 simundump group /kinetics/chain/kinetics[31]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 142.51 16.351 0 simundump kreac /kinetics/chain/kinetics[31]/Ras/dephosph-GEF 1 1 0 "" white \ blue 137.07 17.881 0 simundump kpool /kinetics/chain/kinetics[31]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 140.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[31]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 140 17 0 simundump kreac /kinetics/chain/kinetics[31]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 141.45 21.352 0 simundump kpool /kinetics/chain/kinetics[31]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 134.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[31]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 135.09 16.086 0 simundump kreac /kinetics/chain/kinetics[31]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 135.45 20.246 0 simundump kpool /kinetics/chain/kinetics[31]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 140.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[31]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 141.56 16.084 0 simundump kpool /kinetics/chain/kinetics[31]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 134.13 14.165 0 simundump kreac /kinetics/chain/kinetics[31]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 135.13 17.165 0 simundump kreac /kinetics/chain/kinetics[31]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 137.1 13.5 0 simundump kreac /kinetics/chain/kinetics[31]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 132.02 15.524 0 simundump kpool /kinetics/chain/kinetics[31]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 129.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[31]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 130.35 17.349 0 simundump kpool /kinetics/chain/kinetics[31]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 134.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[31]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 137.01 12.403 0 simundump kreac /kinetics/chain/kinetics[31]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 135.65 15.338 0 simundump kreac /kinetics/chain/kinetics[31]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 130.49 21.679 0 simundump kpool /kinetics/chain/kinetics[31]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 133.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[31]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 133.02 18.657 0 simundump kreac /kinetics/chain/kinetics[31]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 134.35 22.58 0 simundump group /kinetics/chain/kinetics[31]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 118 21 0 simundump kpool /kinetics/chain/kinetics[31]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 115 30 0 simundump kreac /kinetics/chain/kinetics[31]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 116 33 0 simundump kreac /kinetics/chain/kinetics[31]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 117.6 23.26 0 simundump kpool /kinetics/chain/kinetics[31]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 121.49 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[31]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 122.49 27.397 0 simundump kpool /kinetics/chain/kinetics[31]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 126 24 \ 0 simundump kreac /kinetics/chain/kinetics[31]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 127 27 0 simundump kreac /kinetics/chain/kinetics[31]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 118 30 0 simundump kpool /kinetics/chain/kinetics[31]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 123 27.258 0 simundump kreac /kinetics/chain/kinetics[31]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 124 30.258 0 simundump kreac /kinetics/chain/kinetics[31]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 119.16 26.225 0 simundump kreac /kinetics/chain/kinetics[31]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 124 30 0 simundump kpool /kinetics/chain/kinetics[31]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 121 31 0 simundump kreac /kinetics/chain/kinetics[31]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 122 34 0 simundump kpool /kinetics/chain/kinetics[31]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 110 23 0 simundump kreac /kinetics/chain/kinetics[31]/Ca/diff 0 0.101 0.001 "" white \ black 111 26 0 simundump kreac /kinetics/chain/kinetics[31]/Ras-act-unphosph-raf 0 0 0 "" \ white black 132 8 0 simundump group /kinetics/chain/kinetics[31]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 121 19 0 simundump kpool /kinetics/chain/kinetics[31]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 117 17 0 simundump kreac /kinetics/chain/kinetics[31]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 118 20 0 simundump kpool /kinetics/chain/kinetics[31]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 117 9 0 simundump kenz /kinetics/chain/kinetics[31]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 118 10 0 simundump kreac /kinetics/chain/kinetics[31]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 118 12 0 simundump kpool /kinetics/chain/kinetics[31]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 121 12 0 simundump kreac /kinetics/chain/kinetics[31]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 120 7 0 simundump kpool /kinetics/chain/kinetics[31]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 116 5 0 simundump kpool /kinetics/chain/kinetics[31]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 116 \ 14 0 simundump kenz /kinetics/chain/kinetics[31]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 116 13 0 simundump kreac /kinetics/chain/kinetics[31]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 117 17 0 simundump kpool /kinetics/chain/kinetics[31]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 113 12 0 simundump kreac /kinetics/chain/kinetics[31]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 114 15 0 simundump kreac /kinetics/chain/kinetics[31]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 111 9 0 simundump kreac /kinetics/chain/kinetics[31]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 111 16 0 simundump kpool /kinetics/chain/kinetics[31]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 110 30 0 simundump kreac /kinetics/chain/kinetics[31]/Ca_diff 0 5 5 "" white black 110 \ 26 0 simundump group /kinetics/chain/kinetics[32] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 132 0 0 simundump group /kinetics/chain/kinetics[32]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 128.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[32]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 127.92 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[32]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 128.92 4.5108 0 simundump kreac /kinetics/chain/kinetics[32]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 127.92 -0.12295 0 simundump kreac /kinetics/chain/kinetics[32]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 129.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[32]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 128.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[32]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 129.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[32]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 129.22 6.529 0 simundump kreac /kinetics/chain/kinetics[32]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 130.22 9.529 0 simundump kpool /kinetics/chain/kinetics[32]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 130.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[32]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 131.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[32]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 132.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[32]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 133.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[32]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 128.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[32]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 131 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[32]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 132 1.9143 0 simundump kpool /kinetics/chain/kinetics[32]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 125.87 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[32]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 126.87 3.5971 0 simundump kpool /kinetics/chain/kinetics[32]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 129 11 0 simundump kreac /kinetics/chain/kinetics[32]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 130 14 0 simundump kpool /kinetics/chain/kinetics[32]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 136 -3 0 simundump kpool /kinetics/chain/kinetics[32]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 132 9 0 simundump kenz /kinetics/chain/kinetics[32]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 138 10 0 simundump kenz /kinetics/chain/kinetics[32]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 136 13 0 simundump kenz /kinetics/chain/kinetics[32]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 141 20 0 simundump kpool /kinetics/chain/kinetics[32]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 145 1 \ 0 simundump kenz /kinetics/chain/kinetics[32]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 142 10 0 simundump kreac /kinetics/chain/kinetics[32]/MAPK*/diff 0 0.101 0.001 "" \ white black 146 4 0 simundump group /kinetics/chain/kinetics[32]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 147 11 0 simundump kpool /kinetics/chain/kinetics[32]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 138 8 0 simundump kreac /kinetics/chain/kinetics[32]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 139 11 0 simundump kpool /kinetics/chain/kinetics[32]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 141 8 0 simundump kreac /kinetics/chain/kinetics[32]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 142 11 0 simundump kpool /kinetics/chain/kinetics[32]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 138 4 0 simundump kreac /kinetics/chain/kinetics[32]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 139 7 0 simundump kpool /kinetics/chain/kinetics[32]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 138 1 0 simundump kreac /kinetics/chain/kinetics[32]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 139 4 0 simundump kpool /kinetics/chain/kinetics[32]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 144 8 0 simundump kreac /kinetics/chain/kinetics[32]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 145 11 0 simundump kpool /kinetics/chain/kinetics[32]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 141 1 0 simundump kreac /kinetics/chain/kinetics[32]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 142 4 0 simundump kpool /kinetics/chain/kinetics[32]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 145 4 \ 0 simundump kenz /kinetics/chain/kinetics[32]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 140 3 \ 0 simundump kenz /kinetics/chain/kinetics[32]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 145 3 \ 0 simundump kreac /kinetics/chain/kinetics[32]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 146 7 0 simundump kpool /kinetics/chain/kinetics[32]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 141 4 0 simundump kreac /kinetics/chain/kinetics[32]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 142 7 0 simundump kpool /kinetics/chain/kinetics[32]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 137 6 0 simundump kenz /kinetics/chain/kinetics[32]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 140 6 0 simundump kenz /kinetics/chain/kinetics[32]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 143 6 0 simundump kreac /kinetics/chain/kinetics[32]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 138 9 0 simundump kpool /kinetics/chain/kinetics[32]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 137 5 0 simundump kenz /kinetics/chain/kinetics[32]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 140 5 0 simundump kenz /kinetics/chain/kinetics[32]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 143 5 0 simundump kreac /kinetics/chain/kinetics[32]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 138 8 0 simundump kpool /kinetics/chain/kinetics[32]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 137 2 0 simundump kenz /kinetics/chain/kinetics[32]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 138 3 0 simundump kenz /kinetics/chain/kinetics[32]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 143 3 0 simundump kreac /kinetics/chain/kinetics[32]/MKP-1/diff 0 0.101 0.001 "" \ white black 138 5 0 simundump kreac /kinetics/chain/kinetics[32]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 135 9 0 simundump kpool /kinetics/chain/kinetics[32]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 141 9 0 simundump kenz /kinetics/chain/kinetics[32]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 140 10 0 simundump kenz /kinetics/chain/kinetics[32]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 143 7 0 simundump kenz /kinetics/chain/kinetics[32]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 140 7 0 simundump kenz /kinetics/chain/kinetics[32]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 144 10 0 simundump kreac /kinetics/chain/kinetics[32]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 142 12 0 simundump group /kinetics/chain/kinetics[32]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 146.51 16.351 0 simundump kreac /kinetics/chain/kinetics[32]/Ras/dephosph-GEF 1 1 0 "" white \ blue 141.07 17.881 0 simundump kpool /kinetics/chain/kinetics[32]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 144.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[32]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 144 17 0 simundump kreac /kinetics/chain/kinetics[32]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 145.45 21.352 0 simundump kpool /kinetics/chain/kinetics[32]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 138.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[32]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 139.09 16.086 0 simundump kreac /kinetics/chain/kinetics[32]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 139.45 20.246 0 simundump kpool /kinetics/chain/kinetics[32]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 144.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[32]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 145.56 16.084 0 simundump kpool /kinetics/chain/kinetics[32]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 138.13 14.165 0 simundump kreac /kinetics/chain/kinetics[32]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 139.13 17.165 0 simundump kreac /kinetics/chain/kinetics[32]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 141.1 13.5 0 simundump kreac /kinetics/chain/kinetics[32]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 136.02 15.524 0 simundump kpool /kinetics/chain/kinetics[32]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 133.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[32]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 134.35 17.349 0 simundump kpool /kinetics/chain/kinetics[32]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 138.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[32]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 141.01 12.403 0 simundump kreac /kinetics/chain/kinetics[32]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 139.65 15.338 0 simundump kreac /kinetics/chain/kinetics[32]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 134.49 21.679 0 simundump kpool /kinetics/chain/kinetics[32]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 137.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[32]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 137.02 18.657 0 simundump kreac /kinetics/chain/kinetics[32]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 138.35 22.58 0 simundump group /kinetics/chain/kinetics[32]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 122 21 0 simundump kpool /kinetics/chain/kinetics[32]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 119 30 0 simundump kreac /kinetics/chain/kinetics[32]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 120 33 0 simundump kreac /kinetics/chain/kinetics[32]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 121.6 23.26 0 simundump kpool /kinetics/chain/kinetics[32]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 125.49 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[32]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 126.49 27.397 0 simundump kpool /kinetics/chain/kinetics[32]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 130 24 \ 0 simundump kreac /kinetics/chain/kinetics[32]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 131 27 0 simundump kreac /kinetics/chain/kinetics[32]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 122 30 0 simundump kpool /kinetics/chain/kinetics[32]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 127 27.258 0 simundump kreac /kinetics/chain/kinetics[32]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 128 30.258 0 simundump kreac /kinetics/chain/kinetics[32]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 123.16 26.225 0 simundump kreac /kinetics/chain/kinetics[32]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 128 30 0 simundump kpool /kinetics/chain/kinetics[32]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 125 31 0 simundump kreac /kinetics/chain/kinetics[32]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 126 34 0 simundump kpool /kinetics/chain/kinetics[32]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 114 23 0 simundump kreac /kinetics/chain/kinetics[32]/Ca/diff 0 0.101 0.001 "" white \ black 115 26 0 simundump kreac /kinetics/chain/kinetics[32]/Ras-act-unphosph-raf 0 0 0 "" \ white black 136 8 0 simundump group /kinetics/chain/kinetics[32]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 125 19 0 simundump kpool /kinetics/chain/kinetics[32]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 121 17 0 simundump kreac /kinetics/chain/kinetics[32]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 122 20 0 simundump kpool /kinetics/chain/kinetics[32]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 121 9 0 simundump kenz /kinetics/chain/kinetics[32]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 122 10 0 simundump kreac /kinetics/chain/kinetics[32]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 122 12 0 simundump kpool /kinetics/chain/kinetics[32]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 125 12 0 simundump kreac /kinetics/chain/kinetics[32]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 124 7 0 simundump kpool /kinetics/chain/kinetics[32]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 120 5 0 simundump kpool /kinetics/chain/kinetics[32]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 120 \ 14 0 simundump kenz /kinetics/chain/kinetics[32]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 120 13 0 simundump kreac /kinetics/chain/kinetics[32]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 121 17 0 simundump kpool /kinetics/chain/kinetics[32]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 117 12 0 simundump kreac /kinetics/chain/kinetics[32]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 118 15 0 simundump kreac /kinetics/chain/kinetics[32]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 115 9 0 simundump kreac /kinetics/chain/kinetics[32]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 115 16 0 simundump kpool /kinetics/chain/kinetics[32]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 114 30 0 simundump kreac /kinetics/chain/kinetics[32]/Ca_diff 0 5 5 "" white black 114 \ 26 0 simundump group /kinetics/chain/kinetics[33] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 136 0 0 simundump group /kinetics/chain/kinetics[33]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 132.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[33]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 131.92 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[33]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 132.92 4.5108 0 simundump kreac /kinetics/chain/kinetics[33]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 131.92 -0.12295 0 simundump kreac /kinetics/chain/kinetics[33]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 133.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[33]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 132.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[33]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 133.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[33]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 133.22 6.529 0 simundump kreac /kinetics/chain/kinetics[33]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 134.22 9.529 0 simundump kpool /kinetics/chain/kinetics[33]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 134.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[33]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 135.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[33]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 136.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[33]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 137.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[33]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 132.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[33]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 135 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[33]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 136 1.9143 0 simundump kpool /kinetics/chain/kinetics[33]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 129.87 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[33]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 130.87 3.5971 0 simundump kpool /kinetics/chain/kinetics[33]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 133 11 0 simundump kreac /kinetics/chain/kinetics[33]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 134 14 0 simundump kpool /kinetics/chain/kinetics[33]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 140 -3 0 simundump kpool /kinetics/chain/kinetics[33]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 136 9 0 simundump kenz /kinetics/chain/kinetics[33]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 142 10 0 simundump kenz /kinetics/chain/kinetics[33]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 140 13 0 simundump kenz /kinetics/chain/kinetics[33]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 145 20 0 simundump kpool /kinetics/chain/kinetics[33]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 149 1 \ 0 simundump kenz /kinetics/chain/kinetics[33]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 146 10 0 simundump kreac /kinetics/chain/kinetics[33]/MAPK*/diff 0 0.101 0.001 "" \ white black 150 4 0 simundump group /kinetics/chain/kinetics[33]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 151 11 0 simundump kpool /kinetics/chain/kinetics[33]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 142 8 0 simundump kreac /kinetics/chain/kinetics[33]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 143 11 0 simundump kpool /kinetics/chain/kinetics[33]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 145 8 0 simundump kreac /kinetics/chain/kinetics[33]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 146 11 0 simundump kpool /kinetics/chain/kinetics[33]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 142 4 0 simundump kreac /kinetics/chain/kinetics[33]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 143 7 0 simundump kpool /kinetics/chain/kinetics[33]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 142 1 0 simundump kreac /kinetics/chain/kinetics[33]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 143 4 0 simundump kpool /kinetics/chain/kinetics[33]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 148 8 0 simundump kreac /kinetics/chain/kinetics[33]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 149 11 0 simundump kpool /kinetics/chain/kinetics[33]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 145 1 0 simundump kreac /kinetics/chain/kinetics[33]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 146 4 0 simundump kpool /kinetics/chain/kinetics[33]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 149 4 \ 0 simundump kenz /kinetics/chain/kinetics[33]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 144 3 \ 0 simundump kenz /kinetics/chain/kinetics[33]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 149 3 \ 0 simundump kreac /kinetics/chain/kinetics[33]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 150 7 0 simundump kpool /kinetics/chain/kinetics[33]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 145 4 0 simundump kreac /kinetics/chain/kinetics[33]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 146 7 0 simundump kpool /kinetics/chain/kinetics[33]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 141 6 0 simundump kenz /kinetics/chain/kinetics[33]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 144 6 0 simundump kenz /kinetics/chain/kinetics[33]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 147 6 0 simundump kreac /kinetics/chain/kinetics[33]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 142 9 0 simundump kpool /kinetics/chain/kinetics[33]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 141 5 0 simundump kenz /kinetics/chain/kinetics[33]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 144 5 0 simundump kenz /kinetics/chain/kinetics[33]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 147 5 0 simundump kreac /kinetics/chain/kinetics[33]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 142 8 0 simundump kpool /kinetics/chain/kinetics[33]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 141 2 0 simundump kenz /kinetics/chain/kinetics[33]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 142 3 0 simundump kenz /kinetics/chain/kinetics[33]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 147 3 0 simundump kreac /kinetics/chain/kinetics[33]/MKP-1/diff 0 0.101 0.001 "" \ white black 142 5 0 simundump kreac /kinetics/chain/kinetics[33]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 139 9 0 simundump kpool /kinetics/chain/kinetics[33]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 145 9 0 simundump kenz /kinetics/chain/kinetics[33]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 144 10 0 simundump kenz /kinetics/chain/kinetics[33]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 147 7 0 simundump kenz /kinetics/chain/kinetics[33]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 144 7 0 simundump kenz /kinetics/chain/kinetics[33]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 148 10 0 simundump kreac /kinetics/chain/kinetics[33]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 146 12 0 simundump group /kinetics/chain/kinetics[33]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 150.51 16.351 0 simundump kreac /kinetics/chain/kinetics[33]/Ras/dephosph-GEF 1 1 0 "" white \ blue 145.07 17.881 0 simundump kpool /kinetics/chain/kinetics[33]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 148.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[33]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 148 17 0 simundump kreac /kinetics/chain/kinetics[33]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 149.45 21.352 0 simundump kpool /kinetics/chain/kinetics[33]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 142.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[33]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 143.09 16.086 0 simundump kreac /kinetics/chain/kinetics[33]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 143.45 20.246 0 simundump kpool /kinetics/chain/kinetics[33]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 148.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[33]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 149.56 16.084 0 simundump kpool /kinetics/chain/kinetics[33]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 142.13 14.165 0 simundump kreac /kinetics/chain/kinetics[33]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 143.13 17.165 0 simundump kreac /kinetics/chain/kinetics[33]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 145.1 13.5 0 simundump kreac /kinetics/chain/kinetics[33]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 140.02 15.524 0 simundump kpool /kinetics/chain/kinetics[33]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 137.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[33]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 138.35 17.349 0 simundump kpool /kinetics/chain/kinetics[33]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 142.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[33]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 145.01 12.403 0 simundump kreac /kinetics/chain/kinetics[33]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 143.65 15.338 0 simundump kreac /kinetics/chain/kinetics[33]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 138.49 21.679 0 simundump kpool /kinetics/chain/kinetics[33]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 141.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[33]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 141.02 18.657 0 simundump kreac /kinetics/chain/kinetics[33]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 142.35 22.58 0 simundump group /kinetics/chain/kinetics[33]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 126 21 0 simundump kpool /kinetics/chain/kinetics[33]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 123 30 0 simundump kreac /kinetics/chain/kinetics[33]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 124 33 0 simundump kreac /kinetics/chain/kinetics[33]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 125.6 23.26 0 simundump kpool /kinetics/chain/kinetics[33]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 129.49 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[33]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 130.49 27.397 0 simundump kpool /kinetics/chain/kinetics[33]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 134 24 \ 0 simundump kreac /kinetics/chain/kinetics[33]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 135 27 0 simundump kreac /kinetics/chain/kinetics[33]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 126 30 0 simundump kpool /kinetics/chain/kinetics[33]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 131 27.258 0 simundump kreac /kinetics/chain/kinetics[33]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 132 30.258 0 simundump kreac /kinetics/chain/kinetics[33]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 127.16 26.225 0 simundump kreac /kinetics/chain/kinetics[33]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 132 30 0 simundump kpool /kinetics/chain/kinetics[33]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 129 31 0 simundump kreac /kinetics/chain/kinetics[33]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 130 34 0 simundump kpool /kinetics/chain/kinetics[33]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 118 23 0 simundump kreac /kinetics/chain/kinetics[33]/Ca/diff 0 0.101 0.001 "" white \ black 119 26 0 simundump kreac /kinetics/chain/kinetics[33]/Ras-act-unphosph-raf 0 0 0 "" \ white black 140 8 0 simundump group /kinetics/chain/kinetics[33]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 129 19 0 simundump kpool /kinetics/chain/kinetics[33]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 125 17 0 simundump kreac /kinetics/chain/kinetics[33]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 126 20 0 simundump kpool /kinetics/chain/kinetics[33]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 125 9 0 simundump kenz /kinetics/chain/kinetics[33]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 126 10 0 simundump kreac /kinetics/chain/kinetics[33]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 126 12 0 simundump kpool /kinetics/chain/kinetics[33]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 129 12 0 simundump kreac /kinetics/chain/kinetics[33]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 128 7 0 simundump kpool /kinetics/chain/kinetics[33]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 124 5 0 simundump kpool /kinetics/chain/kinetics[33]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 124 \ 14 0 simundump kenz /kinetics/chain/kinetics[33]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 124 13 0 simundump kreac /kinetics/chain/kinetics[33]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 125 17 0 simundump kpool /kinetics/chain/kinetics[33]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 121 12 0 simundump kreac /kinetics/chain/kinetics[33]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 122 15 0 simundump kreac /kinetics/chain/kinetics[33]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 119 9 0 simundump kreac /kinetics/chain/kinetics[33]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 119 16 0 simundump kpool /kinetics/chain/kinetics[33]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 118 30 0 simundump kreac /kinetics/chain/kinetics[33]/Ca_diff 0 5 5 "" white black 118 \ 26 0 simundump group /kinetics/chain/kinetics[34] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 140 0 0 simundump group /kinetics/chain/kinetics[34]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 136.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[34]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 135.92 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[34]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 136.92 4.5108 0 simundump kreac /kinetics/chain/kinetics[34]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 135.92 -0.12295 0 simundump kreac /kinetics/chain/kinetics[34]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 137.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[34]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 136.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[34]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 137.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[34]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 137.22 6.529 0 simundump kreac /kinetics/chain/kinetics[34]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 138.22 9.529 0 simundump kpool /kinetics/chain/kinetics[34]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 138.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[34]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 139.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[34]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 140.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[34]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 141.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[34]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 136.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[34]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 139 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[34]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 140 1.9143 0 simundump kpool /kinetics/chain/kinetics[34]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 133.87 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[34]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 134.87 3.5971 0 simundump kpool /kinetics/chain/kinetics[34]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 137 11 0 simundump kreac /kinetics/chain/kinetics[34]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 138 14 0 simundump kpool /kinetics/chain/kinetics[34]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 144 -3 0 simundump kpool /kinetics/chain/kinetics[34]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 140 9 0 simundump kenz /kinetics/chain/kinetics[34]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 146 10 0 simundump kenz /kinetics/chain/kinetics[34]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 144 13 0 simundump kenz /kinetics/chain/kinetics[34]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 149 20 0 simundump kpool /kinetics/chain/kinetics[34]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 153 1 \ 0 simundump kenz /kinetics/chain/kinetics[34]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 150 10 0 simundump kreac /kinetics/chain/kinetics[34]/MAPK*/diff 0 0.101 0.001 "" \ white black 154 4 0 simundump group /kinetics/chain/kinetics[34]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 155 11 0 simundump kpool /kinetics/chain/kinetics[34]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 146 8 0 simundump kreac /kinetics/chain/kinetics[34]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 147 11 0 simundump kpool /kinetics/chain/kinetics[34]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 149 8 0 simundump kreac /kinetics/chain/kinetics[34]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 150 11 0 simundump kpool /kinetics/chain/kinetics[34]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 146 4 0 simundump kreac /kinetics/chain/kinetics[34]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 147 7 0 simundump kpool /kinetics/chain/kinetics[34]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 146 1 0 simundump kreac /kinetics/chain/kinetics[34]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 147 4 0 simundump kpool /kinetics/chain/kinetics[34]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 152 8 0 simundump kreac /kinetics/chain/kinetics[34]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 153 11 0 simundump kpool /kinetics/chain/kinetics[34]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 149 1 0 simundump kreac /kinetics/chain/kinetics[34]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 150 4 0 simundump kpool /kinetics/chain/kinetics[34]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 153 4 \ 0 simundump kenz /kinetics/chain/kinetics[34]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 148 3 \ 0 simundump kenz /kinetics/chain/kinetics[34]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 153 3 \ 0 simundump kreac /kinetics/chain/kinetics[34]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 154 7 0 simundump kpool /kinetics/chain/kinetics[34]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 149 4 0 simundump kreac /kinetics/chain/kinetics[34]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 150 7 0 simundump kpool /kinetics/chain/kinetics[34]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 145 6 0 simundump kenz /kinetics/chain/kinetics[34]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 148 6 0 simundump kenz /kinetics/chain/kinetics[34]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 151 6 0 simundump kreac /kinetics/chain/kinetics[34]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 146 9 0 simundump kpool /kinetics/chain/kinetics[34]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 145 5 0 simundump kenz /kinetics/chain/kinetics[34]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 148 5 0 simundump kenz /kinetics/chain/kinetics[34]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 151 5 0 simundump kreac /kinetics/chain/kinetics[34]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 146 8 0 simundump kpool /kinetics/chain/kinetics[34]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 145 2 0 simundump kenz /kinetics/chain/kinetics[34]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 146 3 0 simundump kenz /kinetics/chain/kinetics[34]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 151 3 0 simundump kreac /kinetics/chain/kinetics[34]/MKP-1/diff 0 0.101 0.001 "" \ white black 146 5 0 simundump kreac /kinetics/chain/kinetics[34]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 143 9 0 simundump kpool /kinetics/chain/kinetics[34]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 149 9 0 simundump kenz /kinetics/chain/kinetics[34]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 148 10 0 simundump kenz /kinetics/chain/kinetics[34]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 151 7 0 simundump kenz /kinetics/chain/kinetics[34]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 148 7 0 simundump kenz /kinetics/chain/kinetics[34]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 152 10 0 simundump kreac /kinetics/chain/kinetics[34]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 150 12 0 simundump group /kinetics/chain/kinetics[34]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 154.51 16.351 0 simundump kreac /kinetics/chain/kinetics[34]/Ras/dephosph-GEF 1 1 0 "" white \ blue 149.07 17.881 0 simundump kpool /kinetics/chain/kinetics[34]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 152.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[34]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 152 17 0 simundump kreac /kinetics/chain/kinetics[34]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 153.45 21.352 0 simundump kpool /kinetics/chain/kinetics[34]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 146.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[34]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 147.09 16.086 0 simundump kreac /kinetics/chain/kinetics[34]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 147.45 20.246 0 simundump kpool /kinetics/chain/kinetics[34]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 152.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[34]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 153.56 16.084 0 simundump kpool /kinetics/chain/kinetics[34]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 146.13 14.165 0 simundump kreac /kinetics/chain/kinetics[34]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 147.13 17.165 0 simundump kreac /kinetics/chain/kinetics[34]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 149.1 13.5 0 simundump kreac /kinetics/chain/kinetics[34]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 144.02 15.524 0 simundump kpool /kinetics/chain/kinetics[34]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 141.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[34]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 142.35 17.349 0 simundump kpool /kinetics/chain/kinetics[34]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 146.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[34]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 149.01 12.403 0 simundump kreac /kinetics/chain/kinetics[34]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 147.65 15.338 0 simundump kreac /kinetics/chain/kinetics[34]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 142.49 21.679 0 simundump kpool /kinetics/chain/kinetics[34]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 145.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[34]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 145.02 18.657 0 simundump kreac /kinetics/chain/kinetics[34]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 146.35 22.58 0 simundump group /kinetics/chain/kinetics[34]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 130 21 0 simundump kpool /kinetics/chain/kinetics[34]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 127 30 0 simundump kreac /kinetics/chain/kinetics[34]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 128 33 0 simundump kreac /kinetics/chain/kinetics[34]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 129.6 23.26 0 simundump kpool /kinetics/chain/kinetics[34]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 133.49 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[34]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 134.49 27.397 0 simundump kpool /kinetics/chain/kinetics[34]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 138 24 \ 0 simundump kreac /kinetics/chain/kinetics[34]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 139 27 0 simundump kreac /kinetics/chain/kinetics[34]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 130 30 0 simundump kpool /kinetics/chain/kinetics[34]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 135 27.258 0 simundump kreac /kinetics/chain/kinetics[34]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 136 30.258 0 simundump kreac /kinetics/chain/kinetics[34]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 131.16 26.225 0 simundump kreac /kinetics/chain/kinetics[34]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 136 30 0 simundump kpool /kinetics/chain/kinetics[34]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 133 31 0 simundump kreac /kinetics/chain/kinetics[34]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 134 34 0 simundump kpool /kinetics/chain/kinetics[34]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 122 23 0 simundump kreac /kinetics/chain/kinetics[34]/Ca/diff 0 0.101 0.001 "" white \ black 123 26 0 simundump kreac /kinetics/chain/kinetics[34]/Ras-act-unphosph-raf 0 0 0 "" \ white black 144 8 0 simundump group /kinetics/chain/kinetics[34]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 133 19 0 simundump kpool /kinetics/chain/kinetics[34]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 129 17 0 simundump kreac /kinetics/chain/kinetics[34]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 130 20 0 simundump kpool /kinetics/chain/kinetics[34]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 129 9 0 simundump kenz /kinetics/chain/kinetics[34]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 130 10 0 simundump kreac /kinetics/chain/kinetics[34]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 130 12 0 simundump kpool /kinetics/chain/kinetics[34]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 133 12 0 simundump kreac /kinetics/chain/kinetics[34]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 132 7 0 simundump kpool /kinetics/chain/kinetics[34]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 128 5 0 simundump kpool /kinetics/chain/kinetics[34]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 128 \ 14 0 simundump kenz /kinetics/chain/kinetics[34]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 128 13 0 simundump kreac /kinetics/chain/kinetics[34]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 129 17 0 simundump kpool /kinetics/chain/kinetics[34]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 125 12 0 simundump kreac /kinetics/chain/kinetics[34]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 126 15 0 simundump kreac /kinetics/chain/kinetics[34]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 123 9 0 simundump kreac /kinetics/chain/kinetics[34]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 123 16 0 simundump kpool /kinetics/chain/kinetics[34]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 122 30 0 simundump kreac /kinetics/chain/kinetics[34]/Ca_diff 0 5 5 "" white black 122 \ 26 0 simundump group /kinetics/chain/kinetics[35] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 144 0 0 simundump group /kinetics/chain/kinetics[35]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 140.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[35]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 139.92 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[35]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 140.92 4.5108 0 simundump kreac /kinetics/chain/kinetics[35]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 139.92 -0.12295 0 simundump kreac /kinetics/chain/kinetics[35]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 141.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[35]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 140.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[35]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 141.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[35]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 141.22 6.529 0 simundump kreac /kinetics/chain/kinetics[35]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 142.22 9.529 0 simundump kpool /kinetics/chain/kinetics[35]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 142.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[35]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 143.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[35]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 144.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[35]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 145.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[35]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 140.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[35]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 143 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[35]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 144 1.9143 0 simundump kpool /kinetics/chain/kinetics[35]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 137.87 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[35]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 138.87 3.5971 0 simundump kpool /kinetics/chain/kinetics[35]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 141 11 0 simundump kreac /kinetics/chain/kinetics[35]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 142 14 0 simundump kpool /kinetics/chain/kinetics[35]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 148 -3 0 simundump kpool /kinetics/chain/kinetics[35]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 144 9 0 simundump kenz /kinetics/chain/kinetics[35]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 150 10 0 simundump kenz /kinetics/chain/kinetics[35]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 148 13 0 simundump kenz /kinetics/chain/kinetics[35]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 153 20 0 simundump kpool /kinetics/chain/kinetics[35]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 157 1 \ 0 simundump kenz /kinetics/chain/kinetics[35]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 154 10 0 simundump kreac /kinetics/chain/kinetics[35]/MAPK*/diff 0 0.101 0.001 "" \ white black 158 4 0 simundump group /kinetics/chain/kinetics[35]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 159 11 0 simundump kpool /kinetics/chain/kinetics[35]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 150 8 0 simundump kreac /kinetics/chain/kinetics[35]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 151 11 0 simundump kpool /kinetics/chain/kinetics[35]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 153 8 0 simundump kreac /kinetics/chain/kinetics[35]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 154 11 0 simundump kpool /kinetics/chain/kinetics[35]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 150 4 0 simundump kreac /kinetics/chain/kinetics[35]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 151 7 0 simundump kpool /kinetics/chain/kinetics[35]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 150 1 0 simundump kreac /kinetics/chain/kinetics[35]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 151 4 0 simundump kpool /kinetics/chain/kinetics[35]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 156 8 0 simundump kreac /kinetics/chain/kinetics[35]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 157 11 0 simundump kpool /kinetics/chain/kinetics[35]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 153 1 0 simundump kreac /kinetics/chain/kinetics[35]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 154 4 0 simundump kpool /kinetics/chain/kinetics[35]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 157 4 \ 0 simundump kenz /kinetics/chain/kinetics[35]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 152 3 \ 0 simundump kenz /kinetics/chain/kinetics[35]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 157 3 \ 0 simundump kreac /kinetics/chain/kinetics[35]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 158 7 0 simundump kpool /kinetics/chain/kinetics[35]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 153 4 0 simundump kreac /kinetics/chain/kinetics[35]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 154 7 0 simundump kpool /kinetics/chain/kinetics[35]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 149 6 0 simundump kenz /kinetics/chain/kinetics[35]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 152 6 0 simundump kenz /kinetics/chain/kinetics[35]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 155 6 0 simundump kreac /kinetics/chain/kinetics[35]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 150 9 0 simundump kpool /kinetics/chain/kinetics[35]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 149 5 0 simundump kenz /kinetics/chain/kinetics[35]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 152 5 0 simundump kenz /kinetics/chain/kinetics[35]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 155 5 0 simundump kreac /kinetics/chain/kinetics[35]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 150 8 0 simundump kpool /kinetics/chain/kinetics[35]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 149 2 0 simundump kenz /kinetics/chain/kinetics[35]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 150 3 0 simundump kenz /kinetics/chain/kinetics[35]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 155 3 0 simundump kreac /kinetics/chain/kinetics[35]/MKP-1/diff 0 0.101 0.001 "" \ white black 150 5 0 simundump kreac /kinetics/chain/kinetics[35]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 147 9 0 simundump kpool /kinetics/chain/kinetics[35]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 153 9 0 simundump kenz /kinetics/chain/kinetics[35]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 152 10 0 simundump kenz /kinetics/chain/kinetics[35]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 155 7 0 simundump kenz /kinetics/chain/kinetics[35]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 152 7 0 simundump kenz /kinetics/chain/kinetics[35]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 156 10 0 simundump kreac /kinetics/chain/kinetics[35]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 154 12 0 simundump group /kinetics/chain/kinetics[35]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 158.51 16.351 0 simundump kreac /kinetics/chain/kinetics[35]/Ras/dephosph-GEF 1 1 0 "" white \ blue 153.07 17.881 0 simundump kpool /kinetics/chain/kinetics[35]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 156.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[35]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 156 17 0 simundump kreac /kinetics/chain/kinetics[35]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 157.45 21.352 0 simundump kpool /kinetics/chain/kinetics[35]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 150.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[35]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 151.09 16.086 0 simundump kreac /kinetics/chain/kinetics[35]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 151.45 20.246 0 simundump kpool /kinetics/chain/kinetics[35]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 156.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[35]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 157.56 16.084 0 simundump kpool /kinetics/chain/kinetics[35]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 150.13 14.165 0 simundump kreac /kinetics/chain/kinetics[35]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 151.13 17.165 0 simundump kreac /kinetics/chain/kinetics[35]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 153.1 13.5 0 simundump kreac /kinetics/chain/kinetics[35]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 148.02 15.524 0 simundump kpool /kinetics/chain/kinetics[35]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 145.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[35]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 146.35 17.349 0 simundump kpool /kinetics/chain/kinetics[35]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 150.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[35]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 153.01 12.403 0 simundump kreac /kinetics/chain/kinetics[35]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 151.65 15.338 0 simundump kreac /kinetics/chain/kinetics[35]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 146.49 21.679 0 simundump kpool /kinetics/chain/kinetics[35]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 149.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[35]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 149.02 18.657 0 simundump kreac /kinetics/chain/kinetics[35]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 150.35 22.58 0 simundump group /kinetics/chain/kinetics[35]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 134 21 0 simundump kpool /kinetics/chain/kinetics[35]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 131 30 0 simundump kreac /kinetics/chain/kinetics[35]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 132 33 0 simundump kreac /kinetics/chain/kinetics[35]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 133.6 23.26 0 simundump kpool /kinetics/chain/kinetics[35]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 137.49 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[35]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 138.49 27.397 0 simundump kpool /kinetics/chain/kinetics[35]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 142 24 \ 0 simundump kreac /kinetics/chain/kinetics[35]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 143 27 0 simundump kreac /kinetics/chain/kinetics[35]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 134 30 0 simundump kpool /kinetics/chain/kinetics[35]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 139 27.258 0 simundump kreac /kinetics/chain/kinetics[35]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 140 30.258 0 simundump kreac /kinetics/chain/kinetics[35]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 135.16 26.225 0 simundump kreac /kinetics/chain/kinetics[35]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 140 30 0 simundump kpool /kinetics/chain/kinetics[35]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 137 31 0 simundump kreac /kinetics/chain/kinetics[35]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 138 34 0 simundump kpool /kinetics/chain/kinetics[35]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 126 23 0 simundump kreac /kinetics/chain/kinetics[35]/Ca/diff 0 0.101 0.001 "" white \ black 127 26 0 simundump kreac /kinetics/chain/kinetics[35]/Ras-act-unphosph-raf 0 0 0 "" \ white black 148 8 0 simundump group /kinetics/chain/kinetics[35]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 137 19 0 simundump kpool /kinetics/chain/kinetics[35]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 133 17 0 simundump kreac /kinetics/chain/kinetics[35]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 134 20 0 simundump kpool /kinetics/chain/kinetics[35]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 133 9 0 simundump kenz /kinetics/chain/kinetics[35]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 134 10 0 simundump kreac /kinetics/chain/kinetics[35]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 134 12 0 simundump kpool /kinetics/chain/kinetics[35]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 137 12 0 simundump kreac /kinetics/chain/kinetics[35]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 136 7 0 simundump kpool /kinetics/chain/kinetics[35]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 132 5 0 simundump kpool /kinetics/chain/kinetics[35]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 132 \ 14 0 simundump kenz /kinetics/chain/kinetics[35]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 132 13 0 simundump kreac /kinetics/chain/kinetics[35]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 133 17 0 simundump kpool /kinetics/chain/kinetics[35]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 129 12 0 simundump kreac /kinetics/chain/kinetics[35]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 130 15 0 simundump kreac /kinetics/chain/kinetics[35]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 127 9 0 simundump kreac /kinetics/chain/kinetics[35]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 127 16 0 simundump kpool /kinetics/chain/kinetics[35]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 126 30 0 simundump kreac /kinetics/chain/kinetics[35]/Ca_diff 0 5 5 "" white black 126 \ 26 0 simundump group /kinetics/chain/kinetics[36] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 148 0 0 simundump group /kinetics/chain/kinetics[36]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 144.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[36]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 143.92 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[36]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 144.92 4.5108 0 simundump kreac /kinetics/chain/kinetics[36]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 143.92 -0.12295 0 simundump kreac /kinetics/chain/kinetics[36]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 145.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[36]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 144.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[36]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 145.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[36]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 145.22 6.529 0 simundump kreac /kinetics/chain/kinetics[36]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 146.22 9.529 0 simundump kpool /kinetics/chain/kinetics[36]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 146.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[36]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 147.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[36]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 148.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[36]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 149.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[36]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 144.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[36]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 147 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[36]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 148 1.9143 0 simundump kpool /kinetics/chain/kinetics[36]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 141.87 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[36]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 142.87 3.5971 0 simundump kpool /kinetics/chain/kinetics[36]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 145 11 0 simundump kreac /kinetics/chain/kinetics[36]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 146 14 0 simundump kpool /kinetics/chain/kinetics[36]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 152 -3 0 simundump kpool /kinetics/chain/kinetics[36]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 148 9 0 simundump kenz /kinetics/chain/kinetics[36]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 154 10 0 simundump kenz /kinetics/chain/kinetics[36]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 152 13 0 simundump kenz /kinetics/chain/kinetics[36]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 157 20 0 simundump kpool /kinetics/chain/kinetics[36]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 161 1 \ 0 simundump kenz /kinetics/chain/kinetics[36]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 158 10 0 simundump kreac /kinetics/chain/kinetics[36]/MAPK*/diff 0 0.101 0.001 "" \ white black 162 4 0 simundump group /kinetics/chain/kinetics[36]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 163 11 0 simundump kpool /kinetics/chain/kinetics[36]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 154 8 0 simundump kreac /kinetics/chain/kinetics[36]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 155 11 0 simundump kpool /kinetics/chain/kinetics[36]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 157 8 0 simundump kreac /kinetics/chain/kinetics[36]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 158 11 0 simundump kpool /kinetics/chain/kinetics[36]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 154 4 0 simundump kreac /kinetics/chain/kinetics[36]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 155 7 0 simundump kpool /kinetics/chain/kinetics[36]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 154 1 0 simundump kreac /kinetics/chain/kinetics[36]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 155 4 0 simundump kpool /kinetics/chain/kinetics[36]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 160 8 0 simundump kreac /kinetics/chain/kinetics[36]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 161 11 0 simundump kpool /kinetics/chain/kinetics[36]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 157 1 0 simundump kreac /kinetics/chain/kinetics[36]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 158 4 0 simundump kpool /kinetics/chain/kinetics[36]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 161 4 \ 0 simundump kenz /kinetics/chain/kinetics[36]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 156 3 \ 0 simundump kenz /kinetics/chain/kinetics[36]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 161 3 \ 0 simundump kreac /kinetics/chain/kinetics[36]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 162 7 0 simundump kpool /kinetics/chain/kinetics[36]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 157 4 0 simundump kreac /kinetics/chain/kinetics[36]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 158 7 0 simundump kpool /kinetics/chain/kinetics[36]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 153 6 0 simundump kenz /kinetics/chain/kinetics[36]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 156 6 0 simundump kenz /kinetics/chain/kinetics[36]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 159 6 0 simundump kreac /kinetics/chain/kinetics[36]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 154 9 0 simundump kpool /kinetics/chain/kinetics[36]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 153 5 0 simundump kenz /kinetics/chain/kinetics[36]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 156 5 0 simundump kenz /kinetics/chain/kinetics[36]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 159 5 0 simundump kreac /kinetics/chain/kinetics[36]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 154 8 0 simundump kpool /kinetics/chain/kinetics[36]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 153 2 0 simundump kenz /kinetics/chain/kinetics[36]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 154 3 0 simundump kenz /kinetics/chain/kinetics[36]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 159 3 0 simundump kreac /kinetics/chain/kinetics[36]/MKP-1/diff 0 0.101 0.001 "" \ white black 154 5 0 simundump kreac /kinetics/chain/kinetics[36]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 151 9 0 simundump kpool /kinetics/chain/kinetics[36]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 157 9 0 simundump kenz /kinetics/chain/kinetics[36]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 156 10 0 simundump kenz /kinetics/chain/kinetics[36]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 159 7 0 simundump kenz /kinetics/chain/kinetics[36]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 156 7 0 simundump kenz /kinetics/chain/kinetics[36]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 160 10 0 simundump kreac /kinetics/chain/kinetics[36]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 158 12 0 simundump group /kinetics/chain/kinetics[36]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 162.51 16.351 0 simundump kreac /kinetics/chain/kinetics[36]/Ras/dephosph-GEF 1 1 0 "" white \ blue 157.07 17.881 0 simundump kpool /kinetics/chain/kinetics[36]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 160.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[36]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 160 17 0 simundump kreac /kinetics/chain/kinetics[36]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 161.45 21.352 0 simundump kpool /kinetics/chain/kinetics[36]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 154.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[36]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 155.09 16.086 0 simundump kreac /kinetics/chain/kinetics[36]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 155.45 20.246 0 simundump kpool /kinetics/chain/kinetics[36]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 160.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[36]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 161.56 16.084 0 simundump kpool /kinetics/chain/kinetics[36]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 154.13 14.165 0 simundump kreac /kinetics/chain/kinetics[36]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 155.13 17.165 0 simundump kreac /kinetics/chain/kinetics[36]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 157.1 13.5 0 simundump kreac /kinetics/chain/kinetics[36]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 152.02 15.524 0 simundump kpool /kinetics/chain/kinetics[36]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 149.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[36]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 150.35 17.349 0 simundump kpool /kinetics/chain/kinetics[36]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 154.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[36]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 157.01 12.403 0 simundump kreac /kinetics/chain/kinetics[36]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 155.65 15.338 0 simundump kreac /kinetics/chain/kinetics[36]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 150.49 21.679 0 simundump kpool /kinetics/chain/kinetics[36]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 153.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[36]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 153.02 18.657 0 simundump kreac /kinetics/chain/kinetics[36]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 154.35 22.58 0 simundump group /kinetics/chain/kinetics[36]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 138 21 0 simundump kpool /kinetics/chain/kinetics[36]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 135 30 0 simundump kreac /kinetics/chain/kinetics[36]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 136 33 0 simundump kreac /kinetics/chain/kinetics[36]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 137.6 23.26 0 simundump kpool /kinetics/chain/kinetics[36]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 141.49 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[36]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 142.49 27.397 0 simundump kpool /kinetics/chain/kinetics[36]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 146 24 \ 0 simundump kreac /kinetics/chain/kinetics[36]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 147 27 0 simundump kreac /kinetics/chain/kinetics[36]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 138 30 0 simundump kpool /kinetics/chain/kinetics[36]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 143 27.258 0 simundump kreac /kinetics/chain/kinetics[36]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 144 30.258 0 simundump kreac /kinetics/chain/kinetics[36]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 139.16 26.225 0 simundump kreac /kinetics/chain/kinetics[36]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 144 30 0 simundump kpool /kinetics/chain/kinetics[36]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 141 31 0 simundump kreac /kinetics/chain/kinetics[36]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 142 34 0 simundump kpool /kinetics/chain/kinetics[36]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 130 23 0 simundump kreac /kinetics/chain/kinetics[36]/Ca/diff 0 0.101 0.001 "" white \ black 131 26 0 simundump kreac /kinetics/chain/kinetics[36]/Ras-act-unphosph-raf 0 0 0 "" \ white black 152 8 0 simundump group /kinetics/chain/kinetics[36]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 141 19 0 simundump kpool /kinetics/chain/kinetics[36]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 137 17 0 simundump kreac /kinetics/chain/kinetics[36]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 138 20 0 simundump kpool /kinetics/chain/kinetics[36]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 137 9 0 simundump kenz /kinetics/chain/kinetics[36]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 138 10 0 simundump kreac /kinetics/chain/kinetics[36]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 138 12 0 simundump kpool /kinetics/chain/kinetics[36]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 141 12 0 simundump kreac /kinetics/chain/kinetics[36]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 140 7 0 simundump kpool /kinetics/chain/kinetics[36]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 136 5 0 simundump kpool /kinetics/chain/kinetics[36]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 136 \ 14 0 simundump kenz /kinetics/chain/kinetics[36]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 136 13 0 simundump kreac /kinetics/chain/kinetics[36]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 137 17 0 simundump kpool /kinetics/chain/kinetics[36]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 133 12 0 simundump kreac /kinetics/chain/kinetics[36]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 134 15 0 simundump kreac /kinetics/chain/kinetics[36]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 131 9 0 simundump kreac /kinetics/chain/kinetics[36]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 131 16 0 simundump kpool /kinetics/chain/kinetics[36]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 130 30 0 simundump kreac /kinetics/chain/kinetics[36]/Ca_diff 0 5 5 "" white black 130 \ 26 0 simundump group /kinetics/chain/kinetics[37] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 152 0 0 simundump group /kinetics/chain/kinetics[37]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 148.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[37]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 0 /kinetics/dendgeom red black 147.92 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[37]/PKC/PKC-Ca/diff 0 0.101 0.001 "" \ white black 148.92 4.5108 0 simundump kreac /kinetics/chain/kinetics[37]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 147.92 -0.12295 0 simundump kreac /kinetics/chain/kinetics[37]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 149.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[37]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 148.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[37]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 149.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[37]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 0 /kinetics/dendgeom pink blue \ 149.22 6.529 0 simundump kreac /kinetics/chain/kinetics[37]/PKC/PKC-Ca-memb*/diff 0 0.101 \ 0.001 "" white black 150.22 9.529 0 simundump kpool /kinetics/chain/kinetics[37]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 0 /kinetics/dendgeom yellow \ blue 150.17 5.5078 0 simundump kreac /kinetics/chain/kinetics[37]/PKC/PKC-DAG-memb*/diff 0 0.101 \ 0.001 "" white black 151.17 8.5078 0 simundump kpool /kinetics/chain/kinetics[37]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 0 /kinetics/dendgeom white \ blue 152.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[37]/PKC/PKC-Ca-DAG/diff 0 0.101 \ 0.001 "" white black 153.23 4.8026 0 simundump kreac /kinetics/chain/kinetics[37]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 148.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[37]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 0 /kinetics/dendgeom white blue 151 \ -1.0857 0 simundump kreac /kinetics/chain/kinetics[37]/PKC/PKC-DAG/diff 0 0.101 0.001 \ "" white black 152 1.9143 0 simundump kpool /kinetics/chain/kinetics[37]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 0 /kinetics/dendgeom white blue 145.87 \ 0.59711 0 simundump kreac /kinetics/chain/kinetics[37]/PKC/PKC-cytosolic/diff 0 0.101 \ 0.001 "" white black 146.87 3.5971 0 simundump kpool /kinetics/chain/kinetics[37]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 0 /kinetics/dendgeom cyan blue 149 11 0 simundump kreac /kinetics/chain/kinetics[37]/PKC/PKM-zeta/diff 0 0.101 0.001 \ "" white black 150 14 0 simundump kpool /kinetics/chain/kinetics[37]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 156 -3 0 simundump kpool /kinetics/chain/kinetics[37]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 2 /kinetics/dendgeom red black 152 9 0 simundump kenz /kinetics/chain/kinetics[37]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 158 10 0 simundump kenz /kinetics/chain/kinetics[37]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 156 13 0 simundump kenz /kinetics/chain/kinetics[37]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 161 20 0 simundump kpool /kinetics/chain/kinetics[37]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 0 /kinetics/dendgeom orange yellow 165 1 \ 0 simundump kenz /kinetics/chain/kinetics[37]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 162 10 0 simundump kreac /kinetics/chain/kinetics[37]/MAPK*/diff 0 0.101 0.001 "" \ white black 166 4 0 simundump group /kinetics/chain/kinetics[37]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 167 11 0 simundump kpool /kinetics/chain/kinetics[37]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 0 /kinetics/dendgeom pink brown 158 8 0 simundump kreac /kinetics/chain/kinetics[37]/MAPK/craf-1/diff 0 0.101 0.001 \ "" white black 159 11 0 simundump kpool /kinetics/chain/kinetics[37]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 0 /kinetics/dendgeom pink brown 161 8 0 simundump kreac /kinetics/chain/kinetics[37]/MAPK/craf-1*/diff 0 0.101 0.001 \ "" white black 162 11 0 simundump kpool /kinetics/chain/kinetics[37]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 0 /kinetics/dendgeom pink brown 158 4 0 simundump kreac /kinetics/chain/kinetics[37]/MAPK/MAPKK/diff 0 0.101 0.001 "" \ white black 159 7 0 simundump kpool /kinetics/chain/kinetics[37]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 0 /kinetics/dendgeom pink brown 158 1 0 simundump kreac /kinetics/chain/kinetics[37]/MAPK/MAPK/diff 0 0.101 0.001 "" \ white black 159 4 0 simundump kpool /kinetics/chain/kinetics[37]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 0 /kinetics/dendgeom hotpink brown \ 164 8 0 simundump kreac /kinetics/chain/kinetics[37]/MAPK/craf-1**/diff 0 0.101 0.001 \ "" white black 165 11 0 simundump kpool /kinetics/chain/kinetics[37]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 0 /kinetics/dendgeom orange brown 161 1 0 simundump kreac /kinetics/chain/kinetics[37]/MAPK/MAPK-tyr/diff 0 0.101 0.001 \ "" white black 162 4 0 simundump kpool /kinetics/chain/kinetics[37]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 0 /kinetics/dendgeom pink brown 165 4 \ 0 simundump kenz /kinetics/chain/kinetics[37]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 160 3 \ 0 simundump kenz /kinetics/chain/kinetics[37]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 165 3 \ 0 simundump kreac /kinetics/chain/kinetics[37]/MAPK/MAPKK*/diff 0 0.101 0.001 \ "" white black 166 7 0 simundump kpool /kinetics/chain/kinetics[37]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 0 /kinetics/dendgeom pink brown 161 4 0 simundump kreac /kinetics/chain/kinetics[37]/MAPK/MAPKK-ser/diff 0 0.101 \ 0.001 "" white black 162 7 0 simundump kpool /kinetics/chain/kinetics[37]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 0 /kinetics/dendgeom 55 brown 157 6 0 simundump kenz /kinetics/chain/kinetics[37]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 160 6 0 simundump kenz /kinetics/chain/kinetics[37]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 163 6 0 simundump kreac /kinetics/chain/kinetics[37]/MAPK/Raf-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 158 9 0 simundump kpool /kinetics/chain/kinetics[37]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 0 /kinetics/dendgeom red brown 157 5 0 simundump kenz /kinetics/chain/kinetics[37]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 160 5 0 simundump kenz /kinetics/chain/kinetics[37]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 163 5 0 simundump kreac /kinetics/chain/kinetics[37]/MAPK/Raf*-GTP-Ras/diff 0 0.101 \ 0.001 "" white black 158 8 0 simundump kpool /kinetics/chain/kinetics[37]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 0 /kinetics/dendgeom hotpink black 157 2 0 simundump kenz /kinetics/chain/kinetics[37]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 158 3 0 simundump kenz /kinetics/chain/kinetics[37]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 163 3 0 simundump kreac /kinetics/chain/kinetics[37]/MKP-1/diff 0 0.101 0.001 "" \ white black 158 5 0 simundump kreac /kinetics/chain/kinetics[37]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 155 9 0 simundump kpool /kinetics/chain/kinetics[37]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 0 /kinetics/dendgeom hotpink yellow 161 9 0 simundump kenz /kinetics/chain/kinetics[37]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 160 10 0 simundump kenz /kinetics/chain/kinetics[37]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 163 7 0 simundump kenz /kinetics/chain/kinetics[37]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 160 7 0 simundump kenz /kinetics/chain/kinetics[37]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 164 10 0 simundump kreac /kinetics/chain/kinetics[37]/PPhosphatase2A/diff 0 0.101 \ 0.001 "" white black 162 12 0 simundump group /kinetics/chain/kinetics[37]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 166.51 16.351 0 simundump kreac /kinetics/chain/kinetics[37]/Ras/dephosph-GEF 1 1 0 "" white \ blue 161.07 17.881 0 simundump kpool /kinetics/chain/kinetics[37]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 0 /kinetics/dendgeom hotpink blue 164.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[37]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 164 17 0 simundump kreac /kinetics/chain/kinetics[37]/Ras/inact-GEF/diff 0 0.101 0.001 \ "" white black 165.45 21.352 0 simundump kpool /kinetics/chain/kinetics[37]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 0 /kinetics/dendgeom hotpink blue 158.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[37]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 159.09 16.086 0 simundump kreac /kinetics/chain/kinetics[37]/Ras/GEF*/diff 0 0.101 0.001 "" \ white black 159.45 20.246 0 simundump kpool /kinetics/chain/kinetics[37]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 0 /kinetics/dendgeom orange blue 164.56 \ 13.084 0 simundump kreac /kinetics/chain/kinetics[37]/Ras/GTP-Ras/diff 0 0.101 0.001 \ "" white black 165.56 16.084 0 simundump kpool /kinetics/chain/kinetics[37]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 0 /kinetics/dendgeom pink blue 158.13 14.165 0 simundump kreac /kinetics/chain/kinetics[37]/Ras/GDP-Ras/diff 0 0.101 0.001 \ "" white black 159.13 17.165 0 simundump kreac /kinetics/chain/kinetics[37]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 161.1 13.5 0 simundump kreac /kinetics/chain/kinetics[37]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 156.02 15.524 0 simundump kpool /kinetics/chain/kinetics[37]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 0 /kinetics/dendgeom red blue 153.35 \ 14.349 0 simundump kreac /kinetics/chain/kinetics[37]/Ras/GAP*/diff 0 0.101 0.001 "" \ white black 154.35 17.349 0 simundump kpool /kinetics/chain/kinetics[37]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 0 /kinetics/dendgeom red blue 158.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[37]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 161.01 12.403 0 simundump kreac /kinetics/chain/kinetics[37]/Ras/GAP/diff 0 0.101 0.001 "" \ white black 159.65 15.338 0 simundump kreac /kinetics/chain/kinetics[37]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 154.49 21.679 0 simundump kpool /kinetics/chain/kinetics[37]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 0 /kinetics/dendgeom pink blue 157.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[37]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 157.02 18.657 0 simundump kreac /kinetics/chain/kinetics[37]/Ras/CaM-GEF/diff 0 0.101 0.001 \ "" white black 158.35 22.58 0 simundump group /kinetics/chain/kinetics[37]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 142 21 0 simundump kpool /kinetics/chain/kinetics[37]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 0 /kinetics/dendgeom pink blue 139 30 0 simundump kreac /kinetics/chain/kinetics[37]/CaM/CaM/diff 0 0.101 0.001 "" \ white black 140 33 0 simundump kreac /kinetics/chain/kinetics[37]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 141.6 23.26 0 simundump kpool /kinetics/chain/kinetics[37]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 0 /kinetics/dendgeom hotpink blue 145.49 \ 24.397 0 simundump kreac /kinetics/chain/kinetics[37]/CaM/CaM-Ca3/diff 0 0.101 0.001 \ "" white black 146.49 27.397 0 simundump kpool /kinetics/chain/kinetics[37]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 0 /kinetics/dendgeom blue blue 150 24 \ 0 simundump kreac /kinetics/chain/kinetics[37]/CaM/CaM-Ca4/diff 0 0.101 0.001 \ "" white black 151 27 0 simundump kreac /kinetics/chain/kinetics[37]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 142 30 0 simundump kpool /kinetics/chain/kinetics[37]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 0 /kinetics/dendgeom pink blue 147 27.258 0 simundump kreac /kinetics/chain/kinetics[37]/CaM/CaM-Ca2/diff 0 0.101 0.001 \ "" white black 148 30.258 0 simundump kreac /kinetics/chain/kinetics[37]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 143.16 26.225 0 simundump kreac /kinetics/chain/kinetics[37]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 148 30 0 simundump kpool /kinetics/chain/kinetics[37]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 0 /kinetics/dendgeom pink blue 145 31 0 simundump kreac /kinetics/chain/kinetics[37]/CaM/CaM-Ca/diff 0 0.101 0.001 "" \ white black 146 34 0 simundump kpool /kinetics/chain/kinetics[37]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 0 /kinetics/dendgeom red black 134 23 0 simundump kreac /kinetics/chain/kinetics[37]/Ca/diff 0 0.101 0.001 "" white \ black 135 26 0 simundump kreac /kinetics/chain/kinetics[37]/Ras-act-unphosph-raf 0 0 0 "" \ white black 156 8 0 simundump group /kinetics/chain/kinetics[37]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 145 19 0 simundump kpool /kinetics/chain/kinetics[37]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 0 /kinetics/dendgeom 7 25 141 17 0 simundump kreac /kinetics/chain/kinetics[37]/PKM/Ca_detector/diff 0 0.101 \ 0.001 "" white black 142 20 0 simundump kpool /kinetics/chain/kinetics[37]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 0 /kinetics/dendgeom 8 25 141 9 0 simundump kenz /kinetics/chain/kinetics[37]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 142 10 0 simundump kreac /kinetics/chain/kinetics[37]/PKM/PKM_synthesis/diff 0 0.101 \ 0.001 "" white black 142 12 0 simundump kpool /kinetics/chain/kinetics[37]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 145 12 0 simundump kreac /kinetics/chain/kinetics[37]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 144 7 0 simundump kpool /kinetics/chain/kinetics[37]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 140 5 0 simundump kpool /kinetics/chain/kinetics[37]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 0 /kinetics/dendgeom 7 25 140 \ 14 0 simundump kenz /kinetics/chain/kinetics[37]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 140 13 0 simundump kreac /kinetics/chain/kinetics[37]/PKM/Ca.detector_complex/diff 0 \ 0.101 0.001 "" white black 141 17 0 simundump kpool /kinetics/chain/kinetics[37]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 0 /kinetics/dendgeom 6 25 137 12 0 simundump kreac /kinetics/chain/kinetics[37]/PKM/PKM_activator/diff 0 0.101 \ 0.001 "" white black 138 15 0 simundump kreac /kinetics/chain/kinetics[37]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 135 9 0 simundump kreac /kinetics/chain/kinetics[37]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 135 16 0 simundump kpool /kinetics/chain/kinetics[37]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 134 30 0 simundump kreac /kinetics/chain/kinetics[37]/Ca_diff 0 5 5 "" white black 134 \ 26 0 simundump group /kinetics/chain/kinetics[38] 0 yellow black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 156 0 0 simundump group /kinetics/chain/kinetics[38]/PKC 0 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 152.95 8.2163 0 simundump kpool /kinetics/chain/kinetics[38]/PKC/PKC-Ca 0 -1e-12 0.078942 \ 0.078942 5951.9 5951.9 0 0 75396 4 /kinetics/dendgeom red black 151.92 \ 1.5108 0 simundump kreac /kinetics/chain/kinetics[38]/PKC/PKC-act-by-Ca 0 7.958e-06 \ 0.5 "" white blue 151.92 -0.12295 0 simundump kreac /kinetics/chain/kinetics[38]/PKC/PKC-act-by-DAG 0 1.061e-07 \ 8.6348 "" white blue 153.94 0.69395 0 simundump kreac /kinetics/chain/kinetics[38]/PKC/PKC-Ca-to-memb 0 1.2705 \ 3.5026 "" white blue 152.2 4.2533 0 simundump kreac /kinetics/chain/kinetics[38]/PKC/PKC-DAG-to-memb 0 1 0.1 "" \ white blue 153.38 2.7362 0 simundump kpool /kinetics/chain/kinetics[38]/PKC/PKC-Ca-memb* 0 -1e-12 \ 0.028634 0.028634 2158.9 2158.9 0 0 75396 4 /kinetics/dendgeom pink blue \ 153.22 6.529 0 simundump kpool /kinetics/chain/kinetics[38]/PKC/PKC-DAG-memb* 0 -1e-12 \ 0.0089225 0.0089225 672.72 672.72 0 0 75396 4 /kinetics/dendgeom yellow \ blue 154.17 5.5078 0 simundump kpool /kinetics/chain/kinetics[38]/PKC/PKC-Ca-DAG 0 -1e-12 \ 0.00089226 0.00089226 67.273 67.273 0 0 75396 4 /kinetics/dendgeom white \ blue 156.23 1.8026 0 simundump kreac /kinetics/chain/kinetics[38]/PKC/PKC-n-DAG 0 7.958e-09 0.1 "" \ white blue 152.99 -1.9902 0 simundump kpool /kinetics/chain/kinetics[38]/PKC/PKC-DAG 0 -1e-12 0.060193 \ 0.060193 4538.3 4538.3 0 0 75396 4 /kinetics/dendgeom white blue 155 \ -1.0857 0 simundump kpool /kinetics/chain/kinetics[38]/PKC/PKC-cytosolic 0 -1e-12 \ 0.8223 0.8223 61998 61998 0 0 75396 4 /kinetics/dendgeom white blue 149.87 \ 0.59711 0 simundump kpool /kinetics/chain/kinetics[38]/PKC/PKM-zeta 0 -1e-12 0.01007 \ 0.01007 759.21 759.21 0 0 75396 4 /kinetics/dendgeom cyan blue 153 11 0 simundump kpool /kinetics/chain/kinetics[38]/DAG 1 -1e-12 12.2 12.2 \ 9.1983e+05 9.1983e+05 0 0 75396 4 /kinetics/dendgeom green black 160 -3 0 simundump kpool /kinetics/chain/kinetics[38]/PKC-active 1 -1e-12 0.047627 \ 0.047626 3590.8 3590.9 0 0 75396 4 /kinetics/dendgeom red black 156 9 0 simundump kenz /kinetics/chain/kinetics[38]/PKC-active/PKC-act-raf 1 \ 0.0011493 0.0011493 86.652 86.652 75396 1.3263e-05 16 4 0 0 "" red yellow \ "" 162 10 0 simundump kenz /kinetics/chain/kinetics[38]/PKC-active/PKC-inact-GAP 1 53.939 \ 53.939 6.778 6.778 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 160 13 0 simundump kenz /kinetics/chain/kinetics[38]/PKC-active/PKC-act-GEF 1 726.99 \ 726.99 91.354 91.354 0.12566 7.958e-05 16 4 0 0 "" red yellow "" 165 20 0 simundump kpool /kinetics/chain/kinetics[38]/MAPK* 1 -1e-12 7.8539e-05 \ 7.8539e-05 5.9215 5.9215 0 0 75396 4 /kinetics/dendgeom orange yellow 169 1 \ 0 simundump kenz /kinetics/chain/kinetics[38]/MAPK*/MAPK*-feedback 1 3.6779e-08 \ 3.6779e-08 0.002773 0.002773 75396 2.5864e-05 40 10 0 0 "" red orange "" \ 166 10 0 simundump group /kinetics/chain/kinetics[38]/MAPK 0 brown black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 171 11 0 simundump kpool /kinetics/chain/kinetics[38]/MAPK/craf-1 0 0 0.48263 0.48263 \ 36388 36388 0 0 75396 4 /kinetics/dendgeom pink brown 162 8 0 simundump kpool /kinetics/chain/kinetics[38]/MAPK/craf-1* 0 0 0.012007 \ 0.012007 905.28 905.28 0 0 75396 4 /kinetics/dendgeom pink brown 165 8 0 simundump kpool /kinetics/chain/kinetics[38]/MAPK/MAPKK 0 0 0.4946 0.4946 \ 37291 37291 0 0 75396 4 /kinetics/dendgeom pink brown 162 4 0 simundump kpool /kinetics/chain/kinetics[38]/MAPK/MAPK 0 -1e-12 3.5824 3.5824 \ 2.701e+05 2.701e+05 0 0 75396 4 /kinetics/dendgeom pink brown 162 1 0 simundump kpool /kinetics/chain/kinetics[38]/MAPK/craf-1** 1 0 9.6059e-07 \ 9.6059e-07 0.072425 0.072425 0 0 75396 4 /kinetics/dendgeom hotpink brown \ 168 8 0 simundump kpool /kinetics/chain/kinetics[38]/MAPK/MAPK-tyr 1 -1e-12 0.016774 \ 0.016774 1264.7 1264.7 0 0 75396 4 /kinetics/dendgeom orange brown 165 1 0 simundump kpool /kinetics/chain/kinetics[38]/MAPK/MAPKK* 0 0 8.2386e-06 \ 8.2386e-06 0.62116 0.62116 0 0 75396 4 /kinetics/dendgeom pink brown 169 4 \ 0 simundump kenz /kinetics/chain/kinetics[38]/MAPK/MAPKK*/MAPKKtyr 0 0.00063751 \ 0.00063751 48.066 48.066 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 164 3 \ 0 simundump kenz /kinetics/chain/kinetics[38]/MAPK/MAPKK*/MAPKKthr 1 2.985e-06 \ 2.985e-06 0.22506 0.22506 75396 0.00042973 1.2 0.3 0 0 "" red pink "" 169 3 \ 0 simundump kpool /kinetics/chain/kinetics[38]/MAPK/MAPKK-ser 1 0 0.0020188 \ 0.0020188 152.21 152.21 0 0 75396 4 /kinetics/dendgeom pink brown 165 4 0 simundump kpool /kinetics/chain/kinetics[38]/MAPK/Raf-GTP-Ras 0 0 0 0 0 0 0 0 \ 75396 4 /kinetics/dendgeom 55 brown 161 6 0 simundump kenz /kinetics/chain/kinetics[38]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 164 6 0 simundump kenz /kinetics/chain/kinetics[38]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 0 \ 0 0 0 0 75396 0.00012505 1.2 0.3 0 0 "" red 55 "" 167 6 0 simundump kpool /kinetics/chain/kinetics[38]/MAPK/Raf*-GTP-Ras 1 0 0.00082874 \ 0.00082874 62.484 62.484 0 0 75396 4 /kinetics/dendgeom red brown 161 5 0 simundump kenz /kinetics/chain/kinetics[38]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 1 \ 1545.9 1545.9 194.26 194.26 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 164 5 0 simundump kenz /kinetics/chain/kinetics[38]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 1 \ 6.3096 6.3096 0.79287 0.79287 0.12566 0.00012505 1.2 0.3 0 0 "" red red "" \ 167 5 0 simundump kpool /kinetics/chain/kinetics[38]/MKP-1 1 -1e-12 0.019951 0.019951 \ 1504.2 1504.2 0 0 75396 4 /kinetics/dendgeom hotpink black 161 2 0 simundump kenz /kinetics/chain/kinetics[38]/MKP-1/MKP1-tyr-deph 1 4.781e-05 \ 4.781e-05 3.6047 3.6047 75396 3.7895e-05 16 4 0 0 "" red hotpink "" 162 3 0 simundump kenz /kinetics/chain/kinetics[38]/MKP-1/MKP1-thr-deph 1 2.2386e-07 \ 2.2386e-07 0.016878 0.016878 75396 3.7895e-05 16 4 0 0 "" red hotpink "" \ 167 3 0 simundump kreac /kinetics/chain/kinetics[38]/Ras-act-craf 1 0.00013263 0.5 "" \ white black 159 9 0 simundump kpool /kinetics/chain/kinetics[38]/PPhosphatase2A 1 -1e-12 0.9991 \ 0.9991 75328 75328 0 0 75396 4 /kinetics/dendgeom hotpink yellow 165 9 0 simundump kenz /kinetics/chain/kinetics[38]/PPhosphatase2A/craf-deph 1 \ 0.00076621 0.00076621 57.769 57.769 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 164 10 0 simundump kenz /kinetics/chain/kinetics[38]/PPhosphatase2A/MAPKK-deph 1 \ 5.2573e-07 5.2573e-07 0.039638 0.039638 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 167 7 0 simundump kenz /kinetics/chain/kinetics[38]/PPhosphatase2A/MAPKK-deph-ser 1 \ 0.00012882 0.00012882 9.7128 9.7128 75396 2.5414e-05 24 6 0 0 "" red \ hotpink "" 164 7 0 simundump kenz /kinetics/chain/kinetics[38]/PPhosphatase2A/craf**-deph 1 \ 0.036779 0.036779 0.0046216 0.0046216 0.12566 2.5414e-05 24 6 0 0 "" red \ hotpink "" 168 10 0 simundump group /kinetics/chain/kinetics[38]/Ras 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 170.51 16.351 0 simundump kreac /kinetics/chain/kinetics[38]/Ras/dephosph-GEF 1 1 0 "" white \ blue 165.07 17.881 0 simundump kpool /kinetics/chain/kinetics[38]/Ras/inact-GEF 1 -1e-12 0.084803 \ 0.084803 6393.8 6393.8 0 0 75396 4 /kinetics/dendgeom hotpink blue 168.45 \ 18.352 0 simundump kenz /kinetics/chain/kinetics[38]/Ras/inact-GEF/basal_GEF_activity 0 \ 0.0040648 0.0040648 306.47 306.47 75396 1.313e-07 0.08 0.02 0 0 "" red \ hotpink "" 168 17 0 simundump kpool /kinetics/chain/kinetics[38]/Ras/GEF* 1 -1e-12 0.0048465 \ 0.0048465 365.41 365.41 0 0 75396 4 /kinetics/dendgeom hotpink blue 162.45 \ 17.246 0 simundump kenz /kinetics/chain/kinetics[38]/Ras/GEF*/GEF*-act-ras 1 0.0046465 \ 0.0046465 350.33 350.33 75396 2.6261e-06 0.08 0.02 0 0 "" red hotpink "" \ 163.09 16.086 0 simundump kpool /kinetics/chain/kinetics[38]/Ras/GTP-Ras 1 0 0.0034512 \ 0.0034512 260.21 260.21 0 0 75396 4 /kinetics/dendgeom orange blue 168.56 \ 13.084 0 simundump kpool /kinetics/chain/kinetics[38]/Ras/GDP-Ras 1 0 0.48419 0.48419 \ 36506 36506 0 0 75396 4 /kinetics/dendgeom pink blue 162.13 14.165 0 simundump kreac /kinetics/chain/kinetics[38]/Ras/Ras-intrinsic-GTPase 1 1e-04 \ 0 "" white blue 165.1 13.5 0 simundump kreac /kinetics/chain/kinetics[38]/Ras/dephosph-GAP 1 0.1 0 "" \ white blue 160.02 15.524 0 simundump kpool /kinetics/chain/kinetics[38]/Ras/GAP* 1 -1e-12 0.0035959 \ 0.0035959 271.12 271.12 0 0 75396 4 /kinetics/dendgeom red blue 157.35 \ 14.349 0 simundump kpool /kinetics/chain/kinetics[38]/Ras/GAP 1 -1e-12 0.0062918 \ 0.0062918 474.38 474.38 0 0 75396 4 /kinetics/dendgeom red blue 162.65 \ 12.338 0 simundump kenz /kinetics/chain/kinetics[38]/Ras/GAP/GAP-inact-ras 1 \ 2.1491e-05 2.1491e-05 1.6203 1.6203 75396 0.00065634 40 10 0 0 "" red red \ "" 165.01 12.403 0 simundump kreac /kinetics/chain/kinetics[38]/Ras/CaM-bind-GEF 1 0.0026526 1 \ "" white blue 158.49 21.679 0 simundump kpool /kinetics/chain/kinetics[38]/Ras/CaM-GEF 1 -1e-12 0.00021398 \ 0.00021398 16.133 16.133 0 0 75396 4 /kinetics/dendgeom pink blue 161.35 \ 19.58 0 simundump kenz /kinetics/chain/kinetics[38]/Ras/CaM-GEF/CaM-GEF-act-ras 1 \ 0.00020513 0.00020513 15.466 15.466 75396 2.6261e-05 0.8 0.2 0 0 "" red \ pink "" 161.02 18.657 0 simundump group /kinetics/chain/kinetics[38]/CaM 1 blue black x 0 0 "" \ defaultfile defaultfile.g 0 0 0 146 21 0 simundump kpool /kinetics/chain/kinetics[38]/CaM/CaM 1 -1e-12 18.403 18.403 \ 1.3875e+06 1.3875e+06 0 0 75396 4 /kinetics/dendgeom pink blue 143 30 0 simundump kreac /kinetics/chain/kinetics[38]/CaM/CaM-Ca3-bind-Ca 1 6.1675e-06 \ 10 "" white blue 145.6 23.26 0 simundump kpool /kinetics/chain/kinetics[38]/CaM/CaM-Ca3 1 -1e-12 0.0033914 \ 0.0033914 255.7 255.7 0 0 75396 4 /kinetics/dendgeom hotpink blue 149.49 \ 24.397 0 simundump kpool /kinetics/chain/kinetics[38]/CaM/CaM-Ca4 1 -1e-12 1.2616e-05 \ 1.2616e-05 0.95122 0.95122 0 0 75396 4 /kinetics/dendgeom blue blue 154 24 \ 0 simundump kreac /kinetics/chain/kinetics[38]/CaM/CaM-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 146 30 0 simundump kpool /kinetics/chain/kinetics[38]/CaM/CaM-Ca2 1 -1e-12 0.11776 \ 0.11776 8878.5 8878.5 0 0 75396 4 /kinetics/dendgeom pink blue 151 27.258 0 simundump kreac /kinetics/chain/kinetics[38]/CaM/CaM-Ca2-bind-Ca 1 4.7748e-05 \ 10 "" white blue 147.16 26.225 0 simundump kreac /kinetics/chain/kinetics[38]/CaM/CaM-Ca-bind-Ca 1 0.00011254 \ 8.4853 "" white blue 152 30 0 simundump kpool /kinetics/chain/kinetics[38]/CaM/CaM-Ca 1 -1e-12 1.472 1.472 \ 1.1098e+05 1.1098e+05 0 0 75396 4 /kinetics/dendgeom pink blue 149 31 0 simundump kpool /kinetics/chain/kinetics[38]/Ca 1 -1e-12 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom red black 138 23 0 simundump kreac /kinetics/chain/kinetics[38]/Ras-act-unphosph-raf 0 0 0 "" \ white black 160 8 0 simundump group /kinetics/chain/kinetics[38]/PKM 0 25 black x 0 0 "" PKM \ defaultfile.g 0 5dc016e940e88c1cc7928f4e096ff523 0 149 19 0 simundump kpool /kinetics/chain/kinetics[38]/PKM/Ca_detector 0 -1e-12 0.99987 \ 0.99987 75386 75386 0 0 75396 4 /kinetics/dendgeom 7 25 145 17 0 simundump kpool /kinetics/chain/kinetics[38]/PKM/PKM_synthesis 0 -1e-12 \ 0.0010085 0.0010085 76.04 76.04 0 0 75396 4 /kinetics/dendgeom 8 25 145 9 0 simundump kenz /kinetics/chain/kinetics[38]/PKM/PKM_synthesis/kenz 0 \ 0.00010086 0.00010086 7.6041 7.6041 75396 3.3159e-07 0.2 0.05 0 0 "" red 8 \ "" 146 10 0 simundump kpool /kinetics/chain/kinetics[38]/PKM/AA_pool 0 -1e-12 1 1 75396 \ 75396 0 0 75396 4 /kinetics/dendgeom 9 25 149 12 0 simundump kreac /kinetics/chain/kinetics[38]/PKM/PKM_degradation 0 0.0005 0 \ "" white 25 148 7 0 simundump kpool /kinetics/chain/kinetics[38]/PKM/degraded_PKM 0 -1e-12 0 0 0 \ 0 0 0 75396 4 /kinetics/dendgeom 7 25 144 5 0 simundump kpool /kinetics/chain/kinetics[38]/PKM/Ca.detector_complex 0 -1e-12 \ 0.00012615 0.00012615 9.5109 9.5109 0 0 75396 4 /kinetics/dendgeom 7 25 144 \ 14 0 simundump kenz /kinetics/chain/kinetics[38]/PKM/Ca.detector_complex/kenz 0 \ 5.0428e-06 5.0428e-06 0.38021 0.38021 75396 2.6526e-06 0.8 0.2 0 0 "" red 7 \ "" 144 13 0 simundump kpool /kinetics/chain/kinetics[38]/PKM/PKM_activator 0 -1e-12 \ 0.19988 0.19988 15070 15070 0 0 75396 4 /kinetics/dendgeom 6 25 141 12 0 simundump kreac /kinetics/chain/kinetics[38]/PKM/turn_off_activator 0 0.001 0 \ "" white 25 139 9 0 simundump kreac /kinetics/chain/kinetics[38]/PKM/trigger_PKM 0 0.00013263 1 \ "" white 25 139 16 0 simundump kpool /kinetics/chain/kinetics[38]/Ca_input 0 0 0.08 0.08 6031.7 \ 6031.7 0 0 75396 4 /kinetics/dendgeom 61 black 138 30 0 simundump kreac /kinetics/chain/kinetics[38]/Ca_diff 0 5 5 "" white black 138 \ 26 0 simundump doqcsinfo /kinetics/doqcsinfo 0 Ajay_Bhalla_2007_ReacDiff2.g \ Ajay_Bhalla_2007_ReacDiff2 network "Upinder S. Bhalla, NCBS" \ "Upinder S. Bhalla, NCBS" "citation here" Rat "Hippocampal CA1" Dendrite \ "Semi-Quantitative match to experiments" \ "Ajay_Bhalla_rec_diff2 (Under Review)" "Exact GENESIS implementation" \ "Replicates original data " 0 0 0 simundump xgraph /graphs/conc1 0 0 5000 0.00087037 0.10434 0 simundump xgraph /graphs/conc2 0 0 5000 0 0.088747 0 simundump xgraph /moregraphs/conc3 0 0 5000 0 1 0 simundump xgraph /moregraphs/conc4 0 0 5000 0 1 0 simundump xcoredraw /edit/draw 0 -20 173 -5 36 simundump xtree /edit/draw/tree 0 \ /kinetics/#[],/kinetics/#[]/#[],/kinetics/#[]/#[]/#[][TYPE!=proto],/kinetics/#[]/#[]/#[][TYPE!=linkinfo]/##[] \ "edit_elm.D ; drag_from_edit.w " auto 0.6 simundump xtext /file/notes 0 1 xtextload /file/notes \ "27 Feb 2006. Updated version of pkm_mapk1.g Set up diffusion constants," \ "or more accurately, decided which molecules should not diffuse." \ "2 March 2006. Based on pkm_mapk2.g, just added Ca_input and" \ "Ca_diff to set up the propagation model with slightly smoother" \ "Ca transients. This matches the PKC-MAPK bis model." \ "Saved as pkm_mapk3.g" \ "13 Mar 2006. Speeded up rates of trigger_PKM 10x from the " \ "pkm_mapk3.g model. Also speeded up Ca_diff rates from tau of 0.25" \ "to tau of 0.1" \ "Saved as pkm_mapk12.g" \ "13 Mar 2006. Same as previous, except the trigger_PKM Kd is" \ "now 1.4142. Saved as" \ "pkm_mapk13.g" \ "17 Marh 2006. Changed Ca trigger for PKM Synthesis to depend on" \ "Ca4.CaM. Also scaled up CaM-GEF-act-ras kcat from 0.02 to 0.4." \ "Saved as pkm_mapk20.g" \ "17 March. Based on pkm_mapk20.g Changed CaM-GEF-act-ras kcat " \ "to 0.2." \ "Saved as pkm_mapk21.g" \ "" \ "19 May 2006. Based on pkm_mapk21.g. Split up initial step of" \ "2Ca binding to CaM into two reactions, in each of which 1 Ca" \ "binds. Improves numerical stability but overall equil should" \ "not change. " \ "Saved as pkm_mapk22.g" \ "19 Sep 2006. Same as above, except that the initial conditions" \ "have been settled." \ "21 Sep 2006. Diffusive version for transport. The end compartments" \ "have been buffered, and the kf for the flux reactions called" \ "diff have been converted to 0.101 for a net transport rate" \ "of 1 micron/sec. Saved as" \ "pkm_mapk22_transp_endbuf_D1e-13.g" \ "" \ "" addmsg /kinetics/PKC/PKC-act-by-Ca /kinetics/PKC/PKC-Ca REAC B A addmsg /kinetics/PKC/PKC-act-by-DAG /kinetics/PKC/PKC-Ca REAC A B addmsg /kinetics/PKC/PKC-Ca-to-memb /kinetics/PKC/PKC-Ca REAC A B addmsg /kinetics/PKC/PKC-Ca/diff /kinetics/PKC/PKC-Ca REAC A B addmsg /kinetics/PKC/PKC-Ca /kinetics/PKC/PKC-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC/PKC-Ca /kinetics/PKC/PKC-Ca/diff PRODUCT n addmsg /kinetics/PKC/PKC-cytosolic /kinetics/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/Ca /kinetics/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/PKC/PKC-Ca /kinetics/PKC/PKC-act-by-Ca PRODUCT n addmsg /kinetics/DAG /kinetics/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/PKC/PKC-Ca /kinetics/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/PKC/PKC-Ca-DAG /kinetics/PKC/PKC-act-by-DAG PRODUCT n addmsg /kinetics/PKC/PKC-Ca /kinetics/PKC/PKC-Ca-to-memb SUBSTRATE n addmsg /kinetics/PKC/PKC-Ca-memb* /kinetics/PKC/PKC-Ca-to-memb PRODUCT n addmsg /kinetics/PKC/PKC-Ca-DAG /kinetics/PKC/PKC-DAG-to-memb SUBSTRATE n addmsg /kinetics/PKC/PKC-DAG-memb* /kinetics/PKC/PKC-DAG-to-memb PRODUCT n addmsg /kinetics/PKC/PKC-Ca-to-memb /kinetics/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/PKC/PKC-Ca-memb*/diff /kinetics/PKC/PKC-Ca-memb* REAC A B addmsg /kinetics/PKC/PKC-Ca-memb* /kinetics/PKC/PKC-Ca-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-memb* /kinetics/PKC/PKC-Ca-memb*/diff PRODUCT n addmsg /kinetics/PKC/PKC-DAG-to-memb /kinetics/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/PKC/PKC-DAG-memb*/diff /kinetics/PKC/PKC-DAG-memb* REAC A B addmsg /kinetics/PKC/PKC-DAG-memb* /kinetics/PKC/PKC-DAG-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC/PKC-DAG-memb* /kinetics/PKC/PKC-DAG-memb*/diff PRODUCT n addmsg /kinetics/PKC/PKC-act-by-DAG /kinetics/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/PKC/PKC-DAG-to-memb /kinetics/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/PKC/PKC-Ca-DAG/diff /kinetics/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/PKC/PKC-Ca-DAG /kinetics/PKC/PKC-Ca-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-DAG /kinetics/PKC/PKC-Ca-DAG/diff PRODUCT n addmsg /kinetics/PKC/PKC-cytosolic /kinetics/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/DAG /kinetics/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/PKC/PKC-DAG /kinetics/PKC/PKC-n-DAG PRODUCT n addmsg /kinetics/PKC/PKC-n-DAG /kinetics/PKC/PKC-DAG REAC B A addmsg /kinetics/PKC/PKC-DAG/diff /kinetics/PKC/PKC-DAG REAC A B addmsg /kinetics/PKC/PKC-DAG /kinetics/PKC/PKC-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC/PKC-DAG /kinetics/PKC/PKC-DAG/diff PRODUCT n addmsg /kinetics/PKC/PKC-act-by-Ca /kinetics/PKC/PKC-cytosolic REAC A B addmsg /kinetics/PKC/PKC-n-DAG /kinetics/PKC/PKC-cytosolic REAC A B addmsg /kinetics/PKC/PKC-cytosolic/diff /kinetics/PKC/PKC-cytosolic REAC A B addmsg /kinetics/PKC/PKC-cytosolic /kinetics/PKC/PKC-cytosolic/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC/PKC-cytosolic /kinetics/PKC/PKC-cytosolic/diff PRODUCT n addmsg /kinetics/PKM/PKM_synthesis/kenz /kinetics/PKC/PKM-zeta MM_PRD pA addmsg /kinetics/PKM/PKM_degradation /kinetics/PKC/PKM-zeta REAC A B addmsg /kinetics/PKC/PKM-zeta/diff /kinetics/PKC/PKM-zeta REAC A B addmsg /kinetics/PKC/PKM-zeta /kinetics/PKC/PKM-zeta/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC/PKM-zeta /kinetics/PKC/PKM-zeta/diff PRODUCT n addmsg /kinetics/PKC/PKC-act-by-DAG /kinetics/DAG REAC A B addmsg /kinetics/PKC/PKC-n-DAG /kinetics/DAG REAC A B addmsg /kinetics/PKC/PKC-Ca-memb* /kinetics/PKC-active SUMTOTAL n nInit addmsg /kinetics/PKC/PKC-DAG-memb* /kinetics/PKC-active SUMTOTAL n nInit addmsg /kinetics/PKC-active/PKC-act-raf /kinetics/PKC-active REAC eA B addmsg /kinetics/PKC-active/PKC-inact-GAP /kinetics/PKC-active REAC eA B addmsg /kinetics/PKC-active/PKC-act-GEF /kinetics/PKC-active REAC eA B addmsg /kinetics/PKC/PKM-zeta /kinetics/PKC-active SUMTOTAL n nInit addmsg /kinetics/PKC-active /kinetics/PKC-active/PKC-act-raf ENZYME n addmsg /kinetics/MAPK/craf-1 /kinetics/PKC-active/PKC-act-raf SUBSTRATE n addmsg /kinetics/PKC-active /kinetics/PKC-active/PKC-inact-GAP ENZYME n addmsg /kinetics/Ras/GAP /kinetics/PKC-active/PKC-inact-GAP SUBSTRATE n addmsg /kinetics/PKC-active /kinetics/PKC-active/PKC-act-GEF ENZYME n addmsg /kinetics/Ras/inact-GEF /kinetics/PKC-active/PKC-act-GEF SUBSTRATE n addmsg /kinetics/MAPK*/MAPK*-feedback /kinetics/MAPK* REAC eA B addmsg /kinetics/MAPK/MAPKK*/MAPKKthr /kinetics/MAPK* MM_PRD pA addmsg /kinetics/MKP-1/MKP1-thr-deph /kinetics/MAPK* REAC sA B addmsg /kinetics/MAPK*/diff /kinetics/MAPK* REAC A B addmsg /kinetics/MAPK* /kinetics/MAPK*/MAPK*-feedback ENZYME n addmsg /kinetics/MAPK/craf-1* /kinetics/MAPK*/MAPK*-feedback SUBSTRATE n addmsg /kinetics/MAPK* /kinetics/MAPK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK* /kinetics/MAPK*/diff PRODUCT n addmsg /kinetics/PKC-active/PKC-act-raf /kinetics/MAPK/craf-1 REAC sA B addmsg /kinetics/PPhosphatase2A/craf-deph /kinetics/MAPK/craf-1 MM_PRD pA addmsg /kinetics/Ras-act-unphosph-raf /kinetics/MAPK/craf-1 REAC A B addmsg /kinetics/MAPK/craf-1/diff /kinetics/MAPK/craf-1 REAC A B addmsg /kinetics/MAPK/craf-1 /kinetics/MAPK/craf-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/craf-1 /kinetics/MAPK/craf-1/diff PRODUCT n addmsg /kinetics/PKC-active/PKC-act-raf /kinetics/MAPK/craf-1* MM_PRD pA addmsg /kinetics/MAPK*/MAPK*-feedback /kinetics/MAPK/craf-1* REAC sA B addmsg /kinetics/PPhosphatase2A/craf-deph /kinetics/MAPK/craf-1* REAC sA B addmsg /kinetics/PPhosphatase2A/craf**-deph /kinetics/MAPK/craf-1* MM_PRD pA addmsg /kinetics/Ras-act-craf /kinetics/MAPK/craf-1* REAC A B addmsg /kinetics/MAPK/craf-1*/diff /kinetics/MAPK/craf-1* REAC A B addmsg /kinetics/MAPK/craf-1* /kinetics/MAPK/craf-1*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/craf-1* /kinetics/MAPK/craf-1*/diff PRODUCT n addmsg /kinetics/PPhosphatase2A/MAPKK-deph-ser /kinetics/MAPK/MAPKK MM_PRD pA addmsg /kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/MAPK/MAPKK REAC sA B addmsg /kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/MAPK/MAPKK REAC sA B addmsg /kinetics/MAPK/MAPKK/diff /kinetics/MAPK/MAPKK REAC A B addmsg /kinetics/MAPK/MAPKK /kinetics/MAPK/MAPKK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/MAPKK /kinetics/MAPK/MAPKK/diff PRODUCT n addmsg /kinetics/MAPK/MAPKK*/MAPKKtyr /kinetics/MAPK/MAPK REAC sA B addmsg /kinetics/MKP-1/MKP1-tyr-deph /kinetics/MAPK/MAPK MM_PRD pA addmsg /kinetics/MAPK/MAPK/diff /kinetics/MAPK/MAPK REAC A B addmsg /kinetics/MAPK/MAPK /kinetics/MAPK/MAPK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/MAPK /kinetics/MAPK/MAPK/diff PRODUCT n addmsg /kinetics/MAPK*/MAPK*-feedback /kinetics/MAPK/craf-1** MM_PRD pA addmsg /kinetics/PPhosphatase2A/craf**-deph /kinetics/MAPK/craf-1** REAC sA B addmsg /kinetics/MAPK/craf-1**/diff /kinetics/MAPK/craf-1** REAC A B addmsg /kinetics/MAPK/craf-1** /kinetics/MAPK/craf-1**/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/craf-1** /kinetics/MAPK/craf-1**/diff PRODUCT n addmsg /kinetics/MAPK/MAPKK*/MAPKKtyr /kinetics/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/MAPK/MAPKK*/MAPKKthr /kinetics/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/MKP-1/MKP1-tyr-deph /kinetics/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/MKP-1/MKP1-thr-deph /kinetics/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/MAPK/MAPK-tyr/diff /kinetics/MAPK/MAPK-tyr REAC A B addmsg /kinetics/MAPK/MAPK-tyr /kinetics/MAPK/MAPK-tyr/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/MAPK-tyr /kinetics/MAPK/MAPK-tyr/diff PRODUCT n addmsg /kinetics/MAPK/MAPKK*/MAPKKtyr /kinetics/MAPK/MAPKK* REAC eA B addmsg /kinetics/MAPK/MAPKK*/MAPKKthr /kinetics/MAPK/MAPKK* REAC eA B addmsg /kinetics/PPhosphatase2A/MAPKK-deph /kinetics/MAPK/MAPKK* REAC sA B addmsg /kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/MAPK/MAPKK*/diff /kinetics/MAPK/MAPKK* REAC A B addmsg /kinetics/MAPK/MAPKK* /kinetics/MAPK/MAPKK*/MAPKKtyr ENZYME n addmsg /kinetics/MAPK/MAPK /kinetics/MAPK/MAPKK*/MAPKKtyr SUBSTRATE n addmsg /kinetics/MAPK/MAPKK* /kinetics/MAPK/MAPKK*/MAPKKthr ENZYME n addmsg /kinetics/MAPK/MAPK-tyr /kinetics/MAPK/MAPKK*/MAPKKthr SUBSTRATE n addmsg /kinetics/MAPK/MAPKK* /kinetics/MAPK/MAPKK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/MAPKK* /kinetics/MAPK/MAPKK*/diff PRODUCT n addmsg /kinetics/PPhosphatase2A/MAPKK-deph /kinetics/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/PPhosphatase2A/MAPKK-deph-ser /kinetics/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/MAPK/MAPKK-ser/diff /kinetics/MAPK/MAPKK-ser REAC A B addmsg /kinetics/MAPK/MAPKK-ser /kinetics/MAPK/MAPKK-ser/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/MAPKK-ser /kinetics/MAPK/MAPKK-ser/diff PRODUCT n addmsg /kinetics/Ras-act-unphosph-raf /kinetics/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/MAPK/Raf-GTP-Ras/diff /kinetics/MAPK/Raf-GTP-Ras REAC A B addmsg /kinetics/MAPK/Raf-GTP-Ras /kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 ENZYME n addmsg /kinetics/MAPK/MAPKK /kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/MAPK/Raf-GTP-Ras /kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 ENZYME n addmsg /kinetics/MAPK/MAPKK-ser /kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/MAPK/Raf-GTP-Ras /kinetics/MAPK/Raf-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras /kinetics/MAPK/Raf-GTP-Ras/diff PRODUCT n addmsg /kinetics/Ras-act-craf /kinetics/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/MAPK/Raf*-GTP-Ras/diff /kinetics/MAPK/Raf*-GTP-Ras REAC A B addmsg /kinetics/MAPK/Raf*-GTP-Ras /kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 ENZYME n addmsg /kinetics/MAPK/MAPKK /kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/MAPK/Raf*-GTP-Ras /kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 ENZYME n addmsg /kinetics/MAPK/MAPKK-ser /kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/MAPK/Raf*-GTP-Ras /kinetics/MAPK/Raf*-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras /kinetics/MAPK/Raf*-GTP-Ras/diff PRODUCT n addmsg /kinetics/MKP-1/MKP1-tyr-deph /kinetics/MKP-1 REAC eA B addmsg /kinetics/MKP-1/MKP1-thr-deph /kinetics/MKP-1 REAC eA B addmsg /kinetics/MKP-1/diff /kinetics/MKP-1 REAC A B addmsg /kinetics/MKP-1 /kinetics/MKP-1/MKP1-tyr-deph ENZYME n addmsg /kinetics/MAPK/MAPK-tyr /kinetics/MKP-1/MKP1-tyr-deph SUBSTRATE n addmsg /kinetics/MKP-1 /kinetics/MKP-1/MKP1-thr-deph ENZYME n addmsg /kinetics/MAPK* /kinetics/MKP-1/MKP1-thr-deph SUBSTRATE n addmsg /kinetics/MKP-1 /kinetics/MKP-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/MKP-1 /kinetics/MKP-1/diff PRODUCT n addmsg /kinetics/MAPK/craf-1* /kinetics/Ras-act-craf SUBSTRATE n addmsg /kinetics/Ras/GTP-Ras /kinetics/Ras-act-craf SUBSTRATE n addmsg /kinetics/MAPK/Raf*-GTP-Ras /kinetics/Ras-act-craf PRODUCT n addmsg /kinetics/PPhosphatase2A/craf-deph /kinetics/PPhosphatase2A REAC eA B addmsg /kinetics/PPhosphatase2A/MAPKK-deph /kinetics/PPhosphatase2A REAC eA B addmsg /kinetics/PPhosphatase2A/MAPKK-deph-ser /kinetics/PPhosphatase2A REAC eA B addmsg /kinetics/PPhosphatase2A/craf**-deph /kinetics/PPhosphatase2A REAC eA B addmsg /kinetics/PPhosphatase2A/diff /kinetics/PPhosphatase2A REAC A B addmsg /kinetics/PPhosphatase2A /kinetics/PPhosphatase2A/craf-deph ENZYME n addmsg /kinetics/MAPK/craf-1* /kinetics/PPhosphatase2A/craf-deph SUBSTRATE n addmsg /kinetics/PPhosphatase2A /kinetics/PPhosphatase2A/MAPKK-deph ENZYME n addmsg /kinetics/MAPK/MAPKK* /kinetics/PPhosphatase2A/MAPKK-deph SUBSTRATE n addmsg /kinetics/PPhosphatase2A /kinetics/PPhosphatase2A/MAPKK-deph-ser ENZYME n addmsg /kinetics/MAPK/MAPKK-ser /kinetics/PPhosphatase2A/MAPKK-deph-ser SUBSTRATE n addmsg /kinetics/PPhosphatase2A /kinetics/PPhosphatase2A/craf**-deph ENZYME n addmsg /kinetics/MAPK/craf-1** /kinetics/PPhosphatase2A/craf**-deph SUBSTRATE n addmsg /kinetics/PPhosphatase2A /kinetics/PPhosphatase2A/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/PPhosphatase2A /kinetics/PPhosphatase2A/diff PRODUCT n addmsg /kinetics/Ras/GEF* /kinetics/Ras/dephosph-GEF SUBSTRATE n addmsg /kinetics/Ras/inact-GEF /kinetics/Ras/dephosph-GEF PRODUCT n addmsg /kinetics/PKC-active/PKC-act-GEF /kinetics/Ras/inact-GEF REAC sA B addmsg /kinetics/Ras/dephosph-GEF /kinetics/Ras/inact-GEF REAC B A addmsg /kinetics/Ras/CaM-bind-GEF /kinetics/Ras/inact-GEF REAC A B addmsg /kinetics/Ras/inact-GEF/basal_GEF_activity /kinetics/Ras/inact-GEF REAC eA B addmsg /kinetics/Ras/inact-GEF/diff /kinetics/Ras/inact-GEF REAC A B addmsg /kinetics/Ras/inact-GEF /kinetics/Ras/inact-GEF/basal_GEF_activity ENZYME n addmsg /kinetics/Ras/GDP-Ras /kinetics/Ras/inact-GEF/basal_GEF_activity SUBSTRATE n addmsg /kinetics/Ras/inact-GEF /kinetics/Ras/inact-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/inact-GEF /kinetics/Ras/inact-GEF/diff PRODUCT n addmsg /kinetics/PKC-active/PKC-act-GEF /kinetics/Ras/GEF* MM_PRD pA addmsg /kinetics/Ras/dephosph-GEF /kinetics/Ras/GEF* REAC A B addmsg /kinetics/Ras/GEF*/GEF*-act-ras /kinetics/Ras/GEF* REAC eA B addmsg /kinetics/Ras/GEF*/diff /kinetics/Ras/GEF* REAC A B addmsg /kinetics/Ras/GEF* /kinetics/Ras/GEF*/GEF*-act-ras ENZYME n addmsg /kinetics/Ras/GDP-Ras /kinetics/Ras/GEF*/GEF*-act-ras SUBSTRATE n addmsg /kinetics/Ras/GEF* /kinetics/Ras/GEF*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/GEF* /kinetics/Ras/GEF*/diff PRODUCT n addmsg /kinetics/Ras/GAP/GAP-inact-ras /kinetics/Ras/GTP-Ras REAC sA B addmsg /kinetics/Ras/Ras-intrinsic-GTPase /kinetics/Ras/GTP-Ras REAC A B addmsg /kinetics/Ras/GEF*/GEF*-act-ras /kinetics/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/Ras-act-craf /kinetics/Ras/GTP-Ras REAC A B addmsg /kinetics/Ras-act-unphosph-raf /kinetics/Ras/GTP-Ras REAC A B addmsg /kinetics/Ras/inact-GEF/basal_GEF_activity /kinetics/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/Ras/GTP-Ras/diff /kinetics/Ras/GTP-Ras REAC A B addmsg /kinetics/Ras/GTP-Ras /kinetics/Ras/GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/GTP-Ras /kinetics/Ras/GTP-Ras/diff PRODUCT n addmsg /kinetics/Ras/GAP/GAP-inact-ras /kinetics/Ras/GDP-Ras MM_PRD pA addmsg /kinetics/Ras/Ras-intrinsic-GTPase /kinetics/Ras/GDP-Ras REAC B A addmsg /kinetics/Ras/GEF*/GEF*-act-ras /kinetics/Ras/GDP-Ras REAC sA B addmsg /kinetics/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/Ras/GDP-Ras REAC sA B addmsg /kinetics/Ras/inact-GEF/basal_GEF_activity /kinetics/Ras/GDP-Ras REAC sA B addmsg /kinetics/Ras/GDP-Ras/diff /kinetics/Ras/GDP-Ras REAC A B addmsg /kinetics/Ras/GDP-Ras /kinetics/Ras/GDP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/GDP-Ras /kinetics/Ras/GDP-Ras/diff PRODUCT n addmsg /kinetics/Ras/GTP-Ras /kinetics/Ras/Ras-intrinsic-GTPase SUBSTRATE n addmsg /kinetics/Ras/GDP-Ras /kinetics/Ras/Ras-intrinsic-GTPase PRODUCT n addmsg /kinetics/Ras/GAP* /kinetics/Ras/dephosph-GAP SUBSTRATE n addmsg /kinetics/Ras/GAP /kinetics/Ras/dephosph-GAP PRODUCT n addmsg /kinetics/PKC-active/PKC-inact-GAP /kinetics/Ras/GAP* MM_PRD pA addmsg /kinetics/Ras/dephosph-GAP /kinetics/Ras/GAP* REAC A B addmsg /kinetics/Ras/GAP*/diff /kinetics/Ras/GAP* REAC A B addmsg /kinetics/Ras/GAP* /kinetics/Ras/GAP*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/GAP* /kinetics/Ras/GAP*/diff PRODUCT n addmsg /kinetics/Ras/GAP/GAP-inact-ras /kinetics/Ras/GAP REAC eA B addmsg /kinetics/PKC-active/PKC-inact-GAP /kinetics/Ras/GAP REAC sA B addmsg /kinetics/Ras/dephosph-GAP /kinetics/Ras/GAP REAC B A addmsg /kinetics/Ras/GAP/diff /kinetics/Ras/GAP REAC A B addmsg /kinetics/Ras/GAP /kinetics/Ras/GAP/GAP-inact-ras ENZYME n addmsg /kinetics/Ras/GTP-Ras /kinetics/Ras/GAP/GAP-inact-ras SUBSTRATE n addmsg /kinetics/Ras/GAP /kinetics/Ras/GAP/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/GAP /kinetics/Ras/GAP/diff PRODUCT n addmsg /kinetics/Ras/inact-GEF /kinetics/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/Ras/CaM-GEF /kinetics/Ras/CaM-bind-GEF PRODUCT n addmsg /kinetics/CaM/CaM-Ca4 /kinetics/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/Ras/CaM-bind-GEF /kinetics/Ras/CaM-GEF REAC B A addmsg /kinetics/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/Ras/CaM-GEF REAC eA B addmsg /kinetics/Ras/CaM-GEF/diff /kinetics/Ras/CaM-GEF REAC A B addmsg /kinetics/Ras/CaM-GEF /kinetics/Ras/CaM-GEF/CaM-GEF-act-ras ENZYME n addmsg /kinetics/Ras/GDP-Ras /kinetics/Ras/CaM-GEF/CaM-GEF-act-ras SUBSTRATE n addmsg /kinetics/Ras/CaM-GEF /kinetics/Ras/CaM-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/CaM-GEF /kinetics/Ras/CaM-GEF/diff PRODUCT n addmsg /kinetics/CaM/CaM-bind-Ca /kinetics/CaM/CaM REAC A B addmsg /kinetics/CaM/CaM/diff /kinetics/CaM/CaM REAC A B addmsg /kinetics/CaM/CaM /kinetics/CaM/CaM/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/CaM/CaM /kinetics/CaM/CaM/diff PRODUCT n addmsg /kinetics/CaM/CaM-Ca3 /kinetics/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/Ca /kinetics/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/CaM/CaM-Ca4 /kinetics/CaM/CaM-Ca3-bind-Ca PRODUCT n addmsg /kinetics/CaM/CaM-Ca2-bind-Ca /kinetics/CaM/CaM-Ca3 REAC B A addmsg /kinetics/CaM/CaM-Ca3-bind-Ca /kinetics/CaM/CaM-Ca3 REAC A B addmsg /kinetics/CaM/CaM-Ca3/diff /kinetics/CaM/CaM-Ca3 REAC A B addmsg /kinetics/CaM/CaM-Ca3 /kinetics/CaM/CaM-Ca3/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca3 /kinetics/CaM/CaM-Ca3/diff PRODUCT n addmsg /kinetics/Ras/CaM-bind-GEF /kinetics/CaM/CaM-Ca4 REAC A B addmsg /kinetics/CaM/CaM-Ca3-bind-Ca /kinetics/CaM/CaM-Ca4 REAC B A addmsg /kinetics/PKM/trigger_PKM /kinetics/CaM/CaM-Ca4 REAC A B addmsg /kinetics/CaM/CaM-Ca4/diff /kinetics/CaM/CaM-Ca4 REAC A B addmsg /kinetics/CaM/CaM-Ca4 /kinetics/CaM/CaM-Ca4/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca4 /kinetics/CaM/CaM-Ca4/diff PRODUCT n addmsg /kinetics/CaM/CaM /kinetics/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/Ca /kinetics/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/CaM/CaM-Ca /kinetics/CaM/CaM-bind-Ca PRODUCT n addmsg /kinetics/CaM/CaM-Ca2-bind-Ca /kinetics/CaM/CaM-Ca2 REAC A B addmsg /kinetics/CaM/CaM-Ca-bind-Ca /kinetics/CaM/CaM-Ca2 REAC B A addmsg /kinetics/CaM/CaM-Ca2/diff /kinetics/CaM/CaM-Ca2 REAC A B addmsg /kinetics/CaM/CaM-Ca2 /kinetics/CaM/CaM-Ca2/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca2 /kinetics/CaM/CaM-Ca2/diff PRODUCT n addmsg /kinetics/CaM/CaM-Ca2 /kinetics/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/Ca /kinetics/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/CaM/CaM-Ca3 /kinetics/CaM/CaM-Ca2-bind-Ca PRODUCT n addmsg /kinetics/CaM/CaM-Ca /kinetics/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/Ca /kinetics/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/CaM/CaM-Ca2 /kinetics/CaM/CaM-Ca-bind-Ca PRODUCT n addmsg /kinetics/CaM/CaM-bind-Ca /kinetics/CaM/CaM-Ca REAC B A addmsg /kinetics/CaM/CaM-Ca-bind-Ca /kinetics/CaM/CaM-Ca REAC A B addmsg /kinetics/CaM/CaM-Ca/diff /kinetics/CaM/CaM-Ca REAC A B addmsg /kinetics/CaM/CaM-Ca /kinetics/CaM/CaM-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca /kinetics/CaM/CaM-Ca/diff PRODUCT n addmsg /kinetics/PKC/PKC-act-by-Ca /kinetics/Ca REAC A B addmsg /kinetics/CaM/CaM-bind-Ca /kinetics/Ca REAC A B addmsg /kinetics/CaM/CaM-Ca2-bind-Ca /kinetics/Ca REAC A B addmsg /kinetics/CaM/CaM-Ca3-bind-Ca /kinetics/Ca REAC A B addmsg /kinetics/Ca_diff /kinetics/Ca REAC B A addmsg /kinetics/CaM/CaM-Ca-bind-Ca /kinetics/Ca REAC A B addmsg /kinetics/Ca/diff /kinetics/Ca REAC A B addmsg /kinetics/Ca /kinetics/Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/Ca /kinetics/Ca/diff PRODUCT n addmsg /kinetics/MAPK/craf-1 /kinetics/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/MAPK/Raf-GTP-Ras /kinetics/Ras-act-unphosph-raf PRODUCT n addmsg /kinetics/Ras/GTP-Ras /kinetics/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/PKM/trigger_PKM /kinetics/PKM/Ca_detector REAC A B addmsg /kinetics/PKM/Ca_detector/diff /kinetics/PKM/Ca_detector REAC A B addmsg /kinetics/PKM/Ca_detector /kinetics/PKM/Ca_detector/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/PKM/Ca_detector /kinetics/PKM/Ca_detector/diff PRODUCT n addmsg /kinetics/PKM/PKM_synthesis/kenz /kinetics/PKM/PKM_synthesis REAC eA B addmsg /kinetics/PKM/Ca.detector_complex/kenz /kinetics/PKM/PKM_synthesis MM_PRD pA addmsg /kinetics/PKM/turn_off_activator /kinetics/PKM/PKM_synthesis REAC A B addmsg /kinetics/PKM/PKM_synthesis/diff /kinetics/PKM/PKM_synthesis REAC A B addmsg /kinetics/PKM/PKM_synthesis /kinetics/PKM/PKM_synthesis/kenz ENZYME n addmsg /kinetics/PKM/AA_pool /kinetics/PKM/PKM_synthesis/kenz SUBSTRATE n addmsg /kinetics/PKM/PKM_synthesis /kinetics/PKM/PKM_synthesis/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/PKM/PKM_synthesis /kinetics/PKM/PKM_synthesis/diff PRODUCT n addmsg /kinetics/PKM/PKM_synthesis/kenz /kinetics/PKM/AA_pool REAC sA B addmsg /kinetics/PKC/PKM-zeta /kinetics/PKM/PKM_degradation SUBSTRATE n addmsg /kinetics/PKM/degraded_PKM /kinetics/PKM/PKM_degradation PRODUCT n addmsg /kinetics/PKM/PKM_degradation /kinetics/PKM/degraded_PKM REAC B A addmsg /kinetics/PKM/Ca.detector_complex/kenz /kinetics/PKM/Ca.detector_complex REAC eA B addmsg /kinetics/PKM/trigger_PKM /kinetics/PKM/Ca.detector_complex REAC B A addmsg /kinetics/PKM/Ca.detector_complex/diff /kinetics/PKM/Ca.detector_complex REAC A B addmsg /kinetics/PKM/Ca.detector_complex /kinetics/PKM/Ca.detector_complex/kenz ENZYME n addmsg /kinetics/PKM/PKM_activator /kinetics/PKM/Ca.detector_complex/kenz SUBSTRATE n addmsg /kinetics/PKM/Ca.detector_complex /kinetics/PKM/Ca.detector_complex/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/PKM/Ca.detector_complex /kinetics/PKM/Ca.detector_complex/diff PRODUCT n addmsg /kinetics/PKM/Ca.detector_complex/kenz /kinetics/PKM/PKM_activator REAC sA B addmsg /kinetics/PKM/turn_off_activator /kinetics/PKM/PKM_activator REAC B A addmsg /kinetics/PKM/PKM_activator/diff /kinetics/PKM/PKM_activator REAC A B addmsg /kinetics/PKM/PKM_activator /kinetics/PKM/PKM_activator/diff SUBSTRATE n addmsg /kinetics/chain/kinetics/PKM/PKM_activator /kinetics/PKM/PKM_activator/diff PRODUCT n addmsg /kinetics/PKM/PKM_synthesis /kinetics/PKM/turn_off_activator SUBSTRATE n addmsg /kinetics/PKM/PKM_activator /kinetics/PKM/turn_off_activator PRODUCT n addmsg /kinetics/PKM/Ca_detector /kinetics/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/PKM/Ca.detector_complex /kinetics/PKM/trigger_PKM PRODUCT n addmsg /kinetics/CaM/CaM-Ca4 /kinetics/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/Ca_diff /kinetics/Ca_input REAC A B addmsg /kinetics/Ca_input /kinetics/Ca_diff SUBSTRATE n addmsg /kinetics/Ca /kinetics/Ca_diff PRODUCT n addmsg /kinetics/chain/kinetics/PKC/PKC-act-by-Ca /kinetics/chain/kinetics/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-act-by-DAG /kinetics/chain/kinetics/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics/PKC/PKC-Ca/diff /kinetics/chain/kinetics/PKC/PKC-Ca REAC A B addmsg /kinetics/PKC/PKC-Ca/diff /kinetics/chain/kinetics/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-Ca /kinetics/chain/kinetics/PKC/PKC-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca /kinetics/chain/kinetics/PKC/PKC-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKC/PKC-Ca /kinetics/chain/kinetics/PKC/PKC-act-by-Ca PRODUCT n addmsg /kinetics/chain/kinetics/PKC/PKC-cytosolic /kinetics/chain/kinetics/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics/Ca /kinetics/chain/kinetics/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC/PKC-Ca /kinetics/chain/kinetics/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-DAG /kinetics/chain/kinetics/PKC/PKC-act-by-DAG PRODUCT n addmsg /kinetics/chain/kinetics/DAG /kinetics/chain/kinetics/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC/PKC-Ca /kinetics/chain/kinetics/PKC/PKC-Ca-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-memb* /kinetics/chain/kinetics/PKC/PKC-Ca-to-memb PRODUCT n addmsg /kinetics/chain/kinetics/PKC/PKC-DAG-memb* /kinetics/chain/kinetics/PKC/PKC-DAG-to-memb PRODUCT n addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-DAG /kinetics/chain/kinetics/PKC/PKC-DAG-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics/PKC/PKC-Ca-memb* REAC A B addmsg /kinetics/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-memb* /kinetics/chain/kinetics/PKC/PKC-Ca-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics/PKC/PKC-Ca-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics/PKC/PKC-DAG-memb* REAC A B addmsg /kinetics/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-DAG-memb* /kinetics/chain/kinetics/PKC/PKC-DAG-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics/PKC/PKC-DAG-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKC/PKC-act-by-DAG /kinetics/chain/kinetics/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-DAG /kinetics/chain/kinetics/PKC/PKC-Ca-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics/PKC/PKC-Ca-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKC/PKC-DAG /kinetics/chain/kinetics/PKC/PKC-n-DAG PRODUCT n addmsg /kinetics/chain/kinetics/PKC/PKC-cytosolic /kinetics/chain/kinetics/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics/DAG /kinetics/chain/kinetics/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC/PKC-n-DAG /kinetics/chain/kinetics/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-DAG/diff /kinetics/chain/kinetics/PKC/PKC-DAG REAC A B addmsg /kinetics/PKC/PKC-DAG/diff /kinetics/chain/kinetics/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-DAG /kinetics/chain/kinetics/PKC/PKC-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-DAG /kinetics/chain/kinetics/PKC/PKC-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKC/PKC-act-by-Ca /kinetics/chain/kinetics/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics/PKC/PKC-n-DAG /kinetics/chain/kinetics/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics/PKC/PKC-cytosolic REAC A B addmsg /kinetics/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics/PKC/PKC-cytosolic REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-cytosolic /kinetics/chain/kinetics/PKC/PKC-cytosolic/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic /kinetics/chain/kinetics/PKC/PKC-cytosolic/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics/PKC/PKM-zeta MM_PRD pA addmsg /kinetics/chain/kinetics/PKM/PKM_degradation /kinetics/chain/kinetics/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics/PKC/PKM-zeta/diff /kinetics/chain/kinetics/PKC/PKM-zeta REAC A B addmsg /kinetics/PKC/PKM-zeta/diff /kinetics/chain/kinetics/PKC/PKM-zeta REAC B A addmsg /kinetics/chain/kinetics/PKC/PKM-zeta /kinetics/chain/kinetics/PKC/PKM-zeta/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKM-zeta /kinetics/chain/kinetics/PKC/PKM-zeta/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKC/PKC-act-by-DAG /kinetics/chain/kinetics/DAG REAC A B addmsg /kinetics/chain/kinetics/PKC/PKC-n-DAG /kinetics/chain/kinetics/DAG REAC A B addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-memb* /kinetics/chain/kinetics/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics/PKC/PKC-DAG-memb* /kinetics/chain/kinetics/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics/PKC/PKM-zeta /kinetics/chain/kinetics/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics/PKC-active/PKC-act-raf /kinetics/chain/kinetics/PKC-active REAC eA B addmsg /kinetics/chain/kinetics/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics/PKC-active REAC eA B addmsg /kinetics/chain/kinetics/PKC-active/PKC-act-GEF /kinetics/chain/kinetics/PKC-active REAC eA B addmsg /kinetics/chain/kinetics/PKC-active /kinetics/chain/kinetics/PKC-active/PKC-act-raf ENZYME n addmsg /kinetics/chain/kinetics/MAPK/craf-1 /kinetics/chain/kinetics/PKC-active/PKC-act-raf SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC-active /kinetics/chain/kinetics/PKC-active/PKC-inact-GAP ENZYME n addmsg /kinetics/chain/kinetics/Ras/GAP /kinetics/chain/kinetics/PKC-active/PKC-inact-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC-active /kinetics/chain/kinetics/PKC-active/PKC-act-GEF ENZYME n addmsg /kinetics/chain/kinetics/Ras/inact-GEF /kinetics/chain/kinetics/PKC-active/PKC-act-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK*/MAPK*-feedback /kinetics/chain/kinetics/MAPK* REAC eA B addmsg /kinetics/chain/kinetics/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics/MAPK* MM_PRD pA addmsg /kinetics/chain/kinetics/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics/MAPK* REAC sA B addmsg /kinetics/chain/kinetics/MAPK*/diff /kinetics/chain/kinetics/MAPK* REAC A B addmsg /kinetics/MAPK*/diff /kinetics/chain/kinetics/MAPK* REAC B A addmsg /kinetics/chain/kinetics/MAPK* /kinetics/chain/kinetics/MAPK*/MAPK*-feedback ENZYME n addmsg /kinetics/chain/kinetics/MAPK/craf-1* /kinetics/chain/kinetics/MAPK*/MAPK*-feedback SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK* /kinetics/chain/kinetics/MAPK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK* /kinetics/chain/kinetics/MAPK*/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKC-active/PKC-act-raf /kinetics/chain/kinetics/MAPK/craf-1 REAC sA B addmsg /kinetics/chain/kinetics/PPhosphatase2A/craf-deph /kinetics/chain/kinetics/MAPK/craf-1 MM_PRD pA addmsg /kinetics/chain/kinetics/Ras-act-unphosph-raf /kinetics/chain/kinetics/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics/MAPK/craf-1/diff /kinetics/chain/kinetics/MAPK/craf-1 REAC A B addmsg /kinetics/MAPK/craf-1/diff /kinetics/chain/kinetics/MAPK/craf-1 REAC B A addmsg /kinetics/chain/kinetics/MAPK/craf-1 /kinetics/chain/kinetics/MAPK/craf-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1 /kinetics/chain/kinetics/MAPK/craf-1/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKC-active/PKC-act-raf /kinetics/chain/kinetics/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics/MAPK*/MAPK*-feedback /kinetics/chain/kinetics/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics/Ras-act-craf /kinetics/chain/kinetics/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics/PPhosphatase2A/craf-deph /kinetics/chain/kinetics/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics/MAPK/craf-1*/diff /kinetics/chain/kinetics/MAPK/craf-1* REAC A B addmsg /kinetics/MAPK/craf-1*/diff /kinetics/chain/kinetics/MAPK/craf-1* REAC B A addmsg /kinetics/chain/kinetics/MAPK/craf-1* /kinetics/chain/kinetics/MAPK/craf-1*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1* /kinetics/chain/kinetics/MAPK/craf-1*/diff PRODUCT n addmsg /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics/MAPK/MAPKK MM_PRD pA addmsg /kinetics/chain/kinetics/MAPK/MAPKK/diff /kinetics/chain/kinetics/MAPK/MAPKK REAC A B addmsg /kinetics/MAPK/MAPKK/diff /kinetics/chain/kinetics/MAPK/MAPKK REAC B A addmsg /kinetics/chain/kinetics/MAPK/MAPKK /kinetics/chain/kinetics/MAPK/MAPKK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK /kinetics/chain/kinetics/MAPK/MAPKK/diff PRODUCT n addmsg /kinetics/chain/kinetics/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics/MAPK/MAPK REAC sA B addmsg /kinetics/chain/kinetics/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics/MAPK/MAPK MM_PRD pA addmsg /kinetics/chain/kinetics/MAPK/MAPK/diff /kinetics/chain/kinetics/MAPK/MAPK REAC A B addmsg /kinetics/MAPK/MAPK/diff /kinetics/chain/kinetics/MAPK/MAPK REAC B A addmsg /kinetics/chain/kinetics/MAPK/MAPK /kinetics/chain/kinetics/MAPK/MAPK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPK /kinetics/chain/kinetics/MAPK/MAPK/diff PRODUCT n addmsg /kinetics/chain/kinetics/MAPK*/MAPK*-feedback /kinetics/chain/kinetics/MAPK/craf-1** MM_PRD pA addmsg /kinetics/chain/kinetics/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics/MAPK/craf-1** REAC sA B addmsg /kinetics/chain/kinetics/MAPK/craf-1**/diff /kinetics/chain/kinetics/MAPK/craf-1** REAC A B addmsg /kinetics/MAPK/craf-1**/diff /kinetics/chain/kinetics/MAPK/craf-1** REAC B A addmsg /kinetics/chain/kinetics/MAPK/craf-1** /kinetics/chain/kinetics/MAPK/craf-1**/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1** /kinetics/chain/kinetics/MAPK/craf-1**/diff PRODUCT n addmsg /kinetics/chain/kinetics/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics/MAPK/MAPK-tyr REAC A B addmsg /kinetics/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics/MAPK/MAPK-tyr REAC B A addmsg /kinetics/chain/kinetics/MAPK/MAPK-tyr /kinetics/chain/kinetics/MAPK/MAPK-tyr/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr /kinetics/chain/kinetics/MAPK/MAPK-tyr/diff PRODUCT n addmsg /kinetics/chain/kinetics/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics/MAPK/MAPKK* REAC sA B addmsg /kinetics/chain/kinetics/MAPK/MAPKK*/diff /kinetics/chain/kinetics/MAPK/MAPKK* REAC A B addmsg /kinetics/MAPK/MAPKK*/diff /kinetics/chain/kinetics/MAPK/MAPKK* REAC B A addmsg /kinetics/chain/kinetics/MAPK/MAPK /kinetics/chain/kinetics/MAPK/MAPKK*/MAPKKtyr SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/MAPKK* /kinetics/chain/kinetics/MAPK/MAPKK*/MAPKKtyr ENZYME n addmsg /kinetics/chain/kinetics/MAPK/MAPK-tyr /kinetics/chain/kinetics/MAPK/MAPKK*/MAPKKthr SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/MAPKK* /kinetics/chain/kinetics/MAPK/MAPKK*/MAPKKthr ENZYME n addmsg /kinetics/chain/kinetics/MAPK/MAPKK* /kinetics/chain/kinetics/MAPK/MAPKK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK* /kinetics/chain/kinetics/MAPK/MAPKK*/diff PRODUCT n addmsg /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics/MAPK/MAPKK-ser REAC A B addmsg /kinetics/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics/MAPK/MAPKK-ser REAC B A addmsg /kinetics/chain/kinetics/MAPK/MAPKK-ser /kinetics/chain/kinetics/MAPK/MAPKK-ser/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser /kinetics/chain/kinetics/MAPK/MAPKK-ser/diff PRODUCT n addmsg /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics/Ras-act-unphosph-raf /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras REAC A B addmsg /kinetics/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics/MAPK/MAPKK /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics/MAPK/MAPKK-ser /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics/Ras-act-craf /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras REAC A B addmsg /kinetics/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics/MAPK/MAPKK /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics/MAPK/MAPKK-ser /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics/MKP-1/diff /kinetics/chain/kinetics/MKP-1 REAC A B addmsg /kinetics/MKP-1/diff /kinetics/chain/kinetics/MKP-1 REAC B A addmsg /kinetics/chain/kinetics/MAPK/MAPK-tyr /kinetics/chain/kinetics/MKP-1/MKP1-tyr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics/MKP-1 /kinetics/chain/kinetics/MKP-1/MKP1-tyr-deph ENZYME n addmsg /kinetics/chain/kinetics/MAPK* /kinetics/chain/kinetics/MKP-1/MKP1-thr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics/MKP-1 /kinetics/chain/kinetics/MKP-1/MKP1-thr-deph ENZYME n addmsg /kinetics/chain/kinetics/MKP-1 /kinetics/chain/kinetics/MKP-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MKP-1 /kinetics/chain/kinetics/MKP-1/diff PRODUCT n addmsg /kinetics/chain/kinetics/MAPK/craf-1* /kinetics/chain/kinetics/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics/Ras-act-craf PRODUCT n addmsg /kinetics/chain/kinetics/Ras/GTP-Ras /kinetics/chain/kinetics/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics/PPhosphatase2A/craf-deph /kinetics/chain/kinetics/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics/PPhosphatase2A/diff /kinetics/chain/kinetics/PPhosphatase2A REAC A B addmsg /kinetics/PPhosphatase2A/diff /kinetics/chain/kinetics/PPhosphatase2A REAC B A addmsg /kinetics/chain/kinetics/MAPK/craf-1* /kinetics/chain/kinetics/PPhosphatase2A/craf-deph SUBSTRATE n addmsg /kinetics/chain/kinetics/PPhosphatase2A /kinetics/chain/kinetics/PPhosphatase2A/craf-deph ENZYME n addmsg /kinetics/chain/kinetics/MAPK/MAPKK* /kinetics/chain/kinetics/PPhosphatase2A/MAPKK-deph SUBSTRATE n addmsg /kinetics/chain/kinetics/PPhosphatase2A /kinetics/chain/kinetics/PPhosphatase2A/MAPKK-deph ENZYME n addmsg /kinetics/chain/kinetics/MAPK/MAPKK-ser /kinetics/chain/kinetics/PPhosphatase2A/MAPKK-deph-ser SUBSTRATE n addmsg /kinetics/chain/kinetics/PPhosphatase2A /kinetics/chain/kinetics/PPhosphatase2A/MAPKK-deph-ser ENZYME n addmsg /kinetics/chain/kinetics/MAPK/craf-1** /kinetics/chain/kinetics/PPhosphatase2A/craf**-deph SUBSTRATE n addmsg /kinetics/chain/kinetics/PPhosphatase2A /kinetics/chain/kinetics/PPhosphatase2A/craf**-deph ENZYME n addmsg /kinetics/chain/kinetics/PPhosphatase2A /kinetics/chain/kinetics/PPhosphatase2A/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A /kinetics/chain/kinetics/PPhosphatase2A/diff PRODUCT n addmsg /kinetics/chain/kinetics/Ras/inact-GEF /kinetics/chain/kinetics/Ras/dephosph-GEF PRODUCT n addmsg /kinetics/chain/kinetics/Ras/GEF* /kinetics/chain/kinetics/Ras/dephosph-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics/PKC-active/PKC-act-GEF /kinetics/chain/kinetics/Ras/inact-GEF REAC sA B addmsg /kinetics/chain/kinetics/Ras/dephosph-GEF /kinetics/chain/kinetics/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics/Ras/inact-GEF REAC eA B addmsg /kinetics/chain/kinetics/Ras/CaM-bind-GEF /kinetics/chain/kinetics/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics/Ras/inact-GEF/diff /kinetics/chain/kinetics/Ras/inact-GEF REAC A B addmsg /kinetics/Ras/inact-GEF/diff /kinetics/chain/kinetics/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics/Ras/inact-GEF /kinetics/chain/kinetics/Ras/inact-GEF/basal_GEF_activity ENZYME n addmsg /kinetics/chain/kinetics/Ras/GDP-Ras /kinetics/chain/kinetics/Ras/inact-GEF/basal_GEF_activity SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/inact-GEF /kinetics/chain/kinetics/Ras/inact-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/inact-GEF /kinetics/chain/kinetics/Ras/inact-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKC-active/PKC-act-GEF /kinetics/chain/kinetics/Ras/GEF* MM_PRD pA addmsg /kinetics/chain/kinetics/Ras/dephosph-GEF /kinetics/chain/kinetics/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics/Ras/GEF* REAC eA B addmsg /kinetics/chain/kinetics/Ras/GEF*/diff /kinetics/chain/kinetics/Ras/GEF* REAC A B addmsg /kinetics/Ras/GEF*/diff /kinetics/chain/kinetics/Ras/GEF* REAC B A addmsg /kinetics/chain/kinetics/Ras/GEF* /kinetics/chain/kinetics/Ras/GEF*/GEF*-act-ras ENZYME n addmsg /kinetics/chain/kinetics/Ras/GDP-Ras /kinetics/chain/kinetics/Ras/GEF*/GEF*-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/GEF* /kinetics/chain/kinetics/Ras/GEF*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/GEF* /kinetics/chain/kinetics/Ras/GEF*/diff PRODUCT n addmsg /kinetics/chain/kinetics/Ras-act-craf /kinetics/chain/kinetics/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics/Ras/GTP-Ras REAC sA B addmsg /kinetics/chain/kinetics/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics/Ras-act-unphosph-raf /kinetics/chain/kinetics/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics/Ras/GTP-Ras/diff /kinetics/chain/kinetics/Ras/GTP-Ras REAC A B addmsg /kinetics/Ras/GTP-Ras/diff /kinetics/chain/kinetics/Ras/GTP-Ras REAC B A addmsg /kinetics/chain/kinetics/Ras/GTP-Ras /kinetics/chain/kinetics/Ras/GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/GTP-Ras /kinetics/chain/kinetics/Ras/GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics/Ras/GDP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics/Ras/GDP-Ras/diff /kinetics/chain/kinetics/Ras/GDP-Ras REAC A B addmsg /kinetics/Ras/GDP-Ras/diff /kinetics/chain/kinetics/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics/Ras/GDP-Ras /kinetics/chain/kinetics/Ras/GDP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/GDP-Ras /kinetics/chain/kinetics/Ras/GDP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics/Ras/GTP-Ras /kinetics/chain/kinetics/Ras/Ras-intrinsic-GTPase SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/GDP-Ras /kinetics/chain/kinetics/Ras/Ras-intrinsic-GTPase PRODUCT n addmsg /kinetics/chain/kinetics/Ras/GAP* /kinetics/chain/kinetics/Ras/dephosph-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/GAP /kinetics/chain/kinetics/Ras/dephosph-GAP PRODUCT n addmsg /kinetics/chain/kinetics/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics/Ras/GAP* MM_PRD pA addmsg /kinetics/chain/kinetics/Ras/dephosph-GAP /kinetics/chain/kinetics/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics/Ras/GAP*/diff /kinetics/chain/kinetics/Ras/GAP* REAC A B addmsg /kinetics/Ras/GAP*/diff /kinetics/chain/kinetics/Ras/GAP* REAC B A addmsg /kinetics/chain/kinetics/Ras/GAP* /kinetics/chain/kinetics/Ras/GAP*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/GAP* /kinetics/chain/kinetics/Ras/GAP*/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics/Ras/GAP REAC sA B addmsg /kinetics/chain/kinetics/Ras/dephosph-GAP /kinetics/chain/kinetics/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics/Ras/GAP REAC eA B addmsg /kinetics/chain/kinetics/Ras/GAP/diff /kinetics/chain/kinetics/Ras/GAP REAC A B addmsg /kinetics/Ras/GAP/diff /kinetics/chain/kinetics/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics/Ras/GTP-Ras /kinetics/chain/kinetics/Ras/GAP/GAP-inact-ras SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/GAP /kinetics/chain/kinetics/Ras/GAP/GAP-inact-ras ENZYME n addmsg /kinetics/chain/kinetics/Ras/GAP /kinetics/chain/kinetics/Ras/GAP/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/GAP /kinetics/chain/kinetics/Ras/GAP/diff PRODUCT n addmsg /kinetics/chain/kinetics/Ras/inact-GEF /kinetics/chain/kinetics/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/CaM-GEF /kinetics/chain/kinetics/Ras/CaM-bind-GEF PRODUCT n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca4 /kinetics/chain/kinetics/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/CaM-bind-GEF /kinetics/chain/kinetics/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics/Ras/CaM-GEF REAC eA B addmsg /kinetics/chain/kinetics/Ras/CaM-GEF/diff /kinetics/chain/kinetics/Ras/CaM-GEF REAC A B addmsg /kinetics/Ras/CaM-GEF/diff /kinetics/chain/kinetics/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics/Ras/GDP-Ras /kinetics/chain/kinetics/Ras/CaM-GEF/CaM-GEF-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics/Ras/CaM-GEF /kinetics/chain/kinetics/Ras/CaM-GEF/CaM-GEF-act-ras ENZYME n addmsg /kinetics/chain/kinetics/Ras/CaM-GEF /kinetics/chain/kinetics/Ras/CaM-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/CaM-GEF /kinetics/chain/kinetics/Ras/CaM-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics/CaM/CaM-bind-Ca /kinetics/chain/kinetics/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics/CaM/CaM/diff /kinetics/chain/kinetics/CaM/CaM REAC A B addmsg /kinetics/CaM/CaM/diff /kinetics/chain/kinetics/CaM/CaM REAC B A addmsg /kinetics/chain/kinetics/CaM/CaM /kinetics/chain/kinetics/CaM/CaM/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/CaM/CaM /kinetics/chain/kinetics/CaM/CaM/diff PRODUCT n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca3 /kinetics/chain/kinetics/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca4 /kinetics/chain/kinetics/CaM/CaM-Ca3-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics/Ca /kinetics/chain/kinetics/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics/CaM/CaM-Ca3/diff /kinetics/chain/kinetics/CaM/CaM-Ca3 REAC A B addmsg /kinetics/CaM/CaM-Ca3/diff /kinetics/chain/kinetics/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics/CaM/CaM-Ca3 /kinetics/chain/kinetics/CaM/CaM-Ca3/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca3 /kinetics/chain/kinetics/CaM/CaM-Ca3/diff PRODUCT n addmsg /kinetics/chain/kinetics/Ras/CaM-bind-GEF /kinetics/chain/kinetics/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics/PKM/trigger_PKM /kinetics/chain/kinetics/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics/CaM/CaM-Ca4/diff /kinetics/chain/kinetics/CaM/CaM-Ca4 REAC A B addmsg /kinetics/CaM/CaM-Ca4/diff /kinetics/chain/kinetics/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics/CaM/CaM-Ca4 /kinetics/chain/kinetics/CaM/CaM-Ca4/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca4 /kinetics/chain/kinetics/CaM/CaM-Ca4/diff PRODUCT n addmsg /kinetics/chain/kinetics/CaM/CaM /kinetics/chain/kinetics/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca /kinetics/chain/kinetics/CaM/CaM-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics/Ca /kinetics/chain/kinetics/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics/CaM/CaM-Ca2/diff /kinetics/chain/kinetics/CaM/CaM-Ca2 REAC A B addmsg /kinetics/CaM/CaM-Ca2/diff /kinetics/chain/kinetics/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics/CaM/CaM-Ca2 /kinetics/chain/kinetics/CaM/CaM-Ca2/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca2 /kinetics/chain/kinetics/CaM/CaM-Ca2/diff PRODUCT n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca3 /kinetics/chain/kinetics/CaM/CaM-Ca2-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca2 /kinetics/chain/kinetics/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics/Ca /kinetics/chain/kinetics/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca2 /kinetics/chain/kinetics/CaM/CaM-Ca-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca /kinetics/chain/kinetics/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics/Ca /kinetics/chain/kinetics/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics/CaM/CaM-bind-Ca /kinetics/chain/kinetics/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics/CaM/CaM-Ca/diff /kinetics/chain/kinetics/CaM/CaM-Ca REAC A B addmsg /kinetics/CaM/CaM-Ca/diff /kinetics/chain/kinetics/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics/CaM/CaM-Ca /kinetics/chain/kinetics/CaM/CaM-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca /kinetics/chain/kinetics/CaM/CaM-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKC/PKC-act-by-Ca /kinetics/chain/kinetics/Ca REAC A B addmsg /kinetics/chain/kinetics/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics/Ca REAC A B addmsg /kinetics/chain/kinetics/CaM/CaM-bind-Ca /kinetics/chain/kinetics/Ca REAC A B addmsg /kinetics/chain/kinetics/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics/Ca REAC A B addmsg /kinetics/chain/kinetics/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics/Ca REAC A B addmsg /kinetics/chain/kinetics/Ca_diff /kinetics/chain/kinetics/Ca REAC B A addmsg /kinetics/chain/kinetics/Ca/diff /kinetics/chain/kinetics/Ca REAC A B addmsg /kinetics/Ca/diff /kinetics/chain/kinetics/Ca REAC B A addmsg /kinetics/chain/kinetics/Ca /kinetics/chain/kinetics/Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ca /kinetics/chain/kinetics/Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics/MAPK/craf-1 /kinetics/chain/kinetics/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics/Ras-act-unphosph-raf PRODUCT n addmsg /kinetics/chain/kinetics/Ras/GTP-Ras /kinetics/chain/kinetics/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics/PKM/trigger_PKM /kinetics/chain/kinetics/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics/PKM/Ca_detector/diff /kinetics/chain/kinetics/PKM/Ca_detector REAC A B addmsg /kinetics/PKM/Ca_detector/diff /kinetics/chain/kinetics/PKM/Ca_detector REAC B A addmsg /kinetics/chain/kinetics/PKM/Ca_detector /kinetics/chain/kinetics/PKM/Ca_detector/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKM/Ca_detector /kinetics/chain/kinetics/PKM/Ca_detector/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics/PKM/PKM_synthesis REAC eA B addmsg /kinetics/chain/kinetics/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics/PKM/PKM_synthesis MM_PRD pA addmsg /kinetics/chain/kinetics/PKM/turn_off_activator /kinetics/chain/kinetics/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics/PKM/PKM_synthesis/diff /kinetics/chain/kinetics/PKM/PKM_synthesis REAC A B addmsg /kinetics/PKM/PKM_synthesis/diff /kinetics/chain/kinetics/PKM/PKM_synthesis REAC B A addmsg /kinetics/chain/kinetics/PKM/PKM_synthesis /kinetics/chain/kinetics/PKM/PKM_synthesis/kenz ENZYME n addmsg /kinetics/chain/kinetics/PKM/AA_pool /kinetics/chain/kinetics/PKM/PKM_synthesis/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics/PKM/PKM_synthesis /kinetics/chain/kinetics/PKM/PKM_synthesis/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKM/PKM_synthesis /kinetics/chain/kinetics/PKM/PKM_synthesis/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics/PKM/AA_pool REAC sA B addmsg /kinetics/chain/kinetics/PKC/PKM-zeta /kinetics/chain/kinetics/PKM/PKM_degradation SUBSTRATE n addmsg /kinetics/chain/kinetics/PKM/degraded_PKM /kinetics/chain/kinetics/PKM/PKM_degradation PRODUCT n addmsg /kinetics/chain/kinetics/PKM/PKM_degradation /kinetics/chain/kinetics/PKM/degraded_PKM REAC B A addmsg /kinetics/chain/kinetics/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics/PKM/Ca.detector_complex REAC eA B addmsg /kinetics/chain/kinetics/PKM/trigger_PKM /kinetics/chain/kinetics/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics/PKM/Ca.detector_complex REAC A B addmsg /kinetics/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics/PKM/Ca.detector_complex /kinetics/chain/kinetics/PKM/Ca.detector_complex/kenz ENZYME n addmsg /kinetics/chain/kinetics/PKM/PKM_activator /kinetics/chain/kinetics/PKM/Ca.detector_complex/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics/PKM/Ca.detector_complex /kinetics/chain/kinetics/PKM/Ca.detector_complex/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex /kinetics/chain/kinetics/PKM/Ca.detector_complex/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics/PKM/PKM_activator REAC sA B addmsg /kinetics/chain/kinetics/PKM/turn_off_activator /kinetics/chain/kinetics/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics/PKM/PKM_activator/diff /kinetics/chain/kinetics/PKM/PKM_activator REAC A B addmsg /kinetics/PKM/PKM_activator/diff /kinetics/chain/kinetics/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics/PKM/PKM_activator /kinetics/chain/kinetics/PKM/PKM_activator/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKM/PKM_activator /kinetics/chain/kinetics/PKM/PKM_activator/diff PRODUCT n addmsg /kinetics/chain/kinetics/PKM/PKM_synthesis /kinetics/chain/kinetics/PKM/turn_off_activator SUBSTRATE n addmsg /kinetics/chain/kinetics/PKM/PKM_activator /kinetics/chain/kinetics/PKM/turn_off_activator PRODUCT n addmsg /kinetics/chain/kinetics/CaM/CaM-Ca4 /kinetics/chain/kinetics/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics/PKM/Ca_detector /kinetics/chain/kinetics/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics/PKM/Ca.detector_complex /kinetics/chain/kinetics/PKM/trigger_PKM PRODUCT n addmsg /kinetics/chain/kinetics/Ca_diff /kinetics/chain/kinetics/Ca_input REAC A B addmsg /kinetics/chain/kinetics/Ca /kinetics/chain/kinetics/Ca_diff PRODUCT n addmsg /kinetics/chain/kinetics/Ca_input /kinetics/chain/kinetics/Ca_diff SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[1]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[1]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[1]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[1]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics/PKC/PKC-Ca/diff /kinetics/chain/kinetics[1]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[1]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca /kinetics/chain/kinetics[1]/PKC/PKC-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca /kinetics/chain/kinetics[1]/PKC/PKC-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca /kinetics/chain/kinetics[1]/PKC/PKC-act-by-Ca PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic /kinetics/chain/kinetics[1]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ca /kinetics/chain/kinetics[1]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca /kinetics/chain/kinetics[1]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[1]/PKC/PKC-act-by-DAG PRODUCT n addmsg /kinetics/chain/kinetics[1]/DAG /kinetics/chain/kinetics[1]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca /kinetics/chain/kinetics[1]/PKC/PKC-Ca-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[1]/PKC/PKC-Ca-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[1]/PKC/PKC-DAG-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[1]/PKC/PKC-DAG-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[1]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[1]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[1]/PKC/PKC-Ca-memb* REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[1]/PKC/PKC-Ca-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[1]/PKC/PKC-Ca-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[1]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[1]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[1]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[1]/PKC/PKC-DAG-memb* REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[1]/PKC/PKC-DAG-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[1]/PKC/PKC-DAG-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[1]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-DAG /kinetics/chain/kinetics[1]/PKC/PKC-n-DAG PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic /kinetics/chain/kinetics[1]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/DAG /kinetics/chain/kinetics[1]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-n-DAG /kinetics/chain/kinetics[1]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics/PKC/PKC-DAG/diff /kinetics/chain/kinetics[1]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[1]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[1]/PKC/PKC-DAG REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKC-DAG /kinetics/chain/kinetics[1]/PKC/PKC-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-DAG /kinetics/chain/kinetics[1]/PKC/PKC-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKC-n-DAG /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic REAC B A addmsg /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[1]/PKC/PKM-zeta MM_PRD pA addmsg /kinetics/chain/kinetics[1]/PKM/PKM_degradation /kinetics/chain/kinetics[1]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics/PKC/PKM-zeta/diff /kinetics/chain/kinetics[1]/PKC/PKM-zeta REAC B A addmsg /kinetics/chain/kinetics[1]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[1]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKM-zeta /kinetics/chain/kinetics[1]/PKC/PKM-zeta/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKM-zeta /kinetics/chain/kinetics[1]/PKC/PKM-zeta/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[1]/DAG REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKC-n-DAG /kinetics/chain/kinetics[1]/DAG REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[1]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[1]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[1]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[1]/PKC/PKM-zeta /kinetics/chain/kinetics[1]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[1]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[1]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[1]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[1]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[1]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[1]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[1]/PKC-active /kinetics/chain/kinetics[1]/PKC-active/PKC-act-raf ENZYME n addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1 /kinetics/chain/kinetics[1]/PKC-active/PKC-act-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC-active /kinetics/chain/kinetics[1]/PKC-active/PKC-inact-GAP ENZYME n addmsg /kinetics/chain/kinetics[1]/Ras/GAP /kinetics/chain/kinetics[1]/PKC-active/PKC-inact-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC-active /kinetics/chain/kinetics[1]/PKC-active/PKC-act-GEF ENZYME n addmsg /kinetics/chain/kinetics[1]/Ras/inact-GEF /kinetics/chain/kinetics[1]/PKC-active/PKC-act-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[1]/MAPK* REAC eA B addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[1]/MAPK* MM_PRD pA addmsg /kinetics/chain/kinetics[1]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[1]/MAPK* REAC sA B addmsg /kinetics/chain/kinetics/MAPK*/diff /kinetics/chain/kinetics[1]/MAPK* REAC B A addmsg /kinetics/chain/kinetics[1]/MAPK*/diff /kinetics/chain/kinetics[1]/MAPK* REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK* /kinetics/chain/kinetics[1]/MAPK*/MAPK*-feedback ENZYME n addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1* /kinetics/chain/kinetics[1]/MAPK*/MAPK*-feedback SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK* /kinetics/chain/kinetics[1]/MAPK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK* /kinetics/chain/kinetics[1]/MAPK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[1]/MAPK/craf-1 REAC sA B addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[1]/MAPK/craf-1 MM_PRD pA addmsg /kinetics/chain/kinetics[1]/Ras-act-unphosph-raf /kinetics/chain/kinetics[1]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics/MAPK/craf-1/diff /kinetics/chain/kinetics[1]/MAPK/craf-1 REAC B A addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1/diff /kinetics/chain/kinetics[1]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1 /kinetics/chain/kinetics[1]/MAPK/craf-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1 /kinetics/chain/kinetics[1]/MAPK/craf-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[1]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[1]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[1]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[1]/Ras-act-craf /kinetics/chain/kinetics[1]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[1]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[1]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics/MAPK/craf-1*/diff /kinetics/chain/kinetics[1]/MAPK/craf-1* REAC B A addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1*/diff /kinetics/chain/kinetics[1]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1* /kinetics/chain/kinetics[1]/MAPK/craf-1*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1* /kinetics/chain/kinetics[1]/MAPK/craf-1*/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[1]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[1]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[1]/MAPK/MAPKK MM_PRD pA addmsg /kinetics/chain/kinetics/MAPK/MAPKK/diff /kinetics/chain/kinetics[1]/MAPK/MAPKK REAC B A addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK/diff /kinetics/chain/kinetics[1]/MAPK/MAPKK REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK /kinetics/chain/kinetics[1]/MAPK/MAPKK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK /kinetics/chain/kinetics[1]/MAPK/MAPKK/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[1]/MAPK/MAPK REAC sA B addmsg /kinetics/chain/kinetics[1]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[1]/MAPK/MAPK MM_PRD pA addmsg /kinetics/chain/kinetics/MAPK/MAPK/diff /kinetics/chain/kinetics[1]/MAPK/MAPK REAC B A addmsg /kinetics/chain/kinetics[1]/MAPK/MAPK/diff /kinetics/chain/kinetics[1]/MAPK/MAPK REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK/MAPK /kinetics/chain/kinetics[1]/MAPK/MAPK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPK /kinetics/chain/kinetics[1]/MAPK/MAPK/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[1]/MAPK/craf-1** MM_PRD pA addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[1]/MAPK/craf-1** REAC sA B addmsg /kinetics/chain/kinetics/MAPK/craf-1**/diff /kinetics/chain/kinetics[1]/MAPK/craf-1** REAC B A addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1**/diff /kinetics/chain/kinetics[1]/MAPK/craf-1** REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1** /kinetics/chain/kinetics[1]/MAPK/craf-1**/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1** /kinetics/chain/kinetics[1]/MAPK/craf-1**/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[1]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[1]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr REAC B A addmsg /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[1]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[1]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[1]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[1]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[1]/MAPK/MAPKK* REAC sA B addmsg /kinetics/chain/kinetics/MAPK/MAPKK*/diff /kinetics/chain/kinetics[1]/MAPK/MAPKK* REAC B A addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[1]/MAPK/MAPKK* REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK/MAPK /kinetics/chain/kinetics[1]/MAPK/MAPKK*/MAPKKtyr SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK* /kinetics/chain/kinetics[1]/MAPK/MAPKK*/MAPKKtyr ENZYME n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr /kinetics/chain/kinetics[1]/MAPK/MAPKK*/MAPKKthr SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK* /kinetics/chain/kinetics[1]/MAPK/MAPKK*/MAPKKthr ENZYME n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK* /kinetics/chain/kinetics[1]/MAPK/MAPKK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK* /kinetics/chain/kinetics[1]/MAPK/MAPKK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser REAC B A addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[1]/Ras-act-unphosph-raf /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[1]/Ras-act-craf /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[1]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[1]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[1]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics/MKP-1/diff /kinetics/chain/kinetics[1]/MKP-1 REAC B A addmsg /kinetics/chain/kinetics[1]/MKP-1/diff /kinetics/chain/kinetics[1]/MKP-1 REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr /kinetics/chain/kinetics[1]/MKP-1/MKP1-tyr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MKP-1 /kinetics/chain/kinetics[1]/MKP-1/MKP1-tyr-deph ENZYME n addmsg /kinetics/chain/kinetics[1]/MAPK* /kinetics/chain/kinetics[1]/MKP-1/MKP1-thr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MKP-1 /kinetics/chain/kinetics[1]/MKP-1/MKP1-thr-deph ENZYME n addmsg /kinetics/chain/kinetics[1]/MKP-1 /kinetics/chain/kinetics[1]/MKP-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MKP-1 /kinetics/chain/kinetics[1]/MKP-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1* /kinetics/chain/kinetics[1]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[1]/Ras-act-craf PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ras/GTP-Ras /kinetics/chain/kinetics[1]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[1]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[1]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[1]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[1]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics/PPhosphatase2A/diff /kinetics/chain/kinetics[1]/PPhosphatase2A REAC B A addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/diff /kinetics/chain/kinetics[1]/PPhosphatase2A REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1* /kinetics/chain/kinetics[1]/PPhosphatase2A/craf-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A /kinetics/chain/kinetics[1]/PPhosphatase2A/craf-deph ENZYME n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK* /kinetics/chain/kinetics[1]/PPhosphatase2A/MAPKK-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A /kinetics/chain/kinetics[1]/PPhosphatase2A/MAPKK-deph ENZYME n addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser /kinetics/chain/kinetics[1]/PPhosphatase2A/MAPKK-deph-ser SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A /kinetics/chain/kinetics[1]/PPhosphatase2A/MAPKK-deph-ser ENZYME n addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1** /kinetics/chain/kinetics[1]/PPhosphatase2A/craf**-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A /kinetics/chain/kinetics[1]/PPhosphatase2A/craf**-deph ENZYME n addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A /kinetics/chain/kinetics[1]/PPhosphatase2A/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A /kinetics/chain/kinetics[1]/PPhosphatase2A/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ras/inact-GEF /kinetics/chain/kinetics[1]/Ras/dephosph-GEF PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ras/GEF* /kinetics/chain/kinetics[1]/Ras/dephosph-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[1]/Ras/inact-GEF REAC sA B addmsg /kinetics/chain/kinetics[1]/Ras/dephosph-GEF /kinetics/chain/kinetics[1]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[1]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[1]/Ras/inact-GEF REAC eA B addmsg /kinetics/chain/kinetics[1]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[1]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics/Ras/inact-GEF/diff /kinetics/chain/kinetics[1]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[1]/Ras/inact-GEF/diff /kinetics/chain/kinetics[1]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[1]/Ras/inact-GEF /kinetics/chain/kinetics[1]/Ras/inact-GEF/basal_GEF_activity ENZYME n addmsg /kinetics/chain/kinetics[1]/Ras/GDP-Ras /kinetics/chain/kinetics[1]/Ras/inact-GEF/basal_GEF_activity SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/inact-GEF /kinetics/chain/kinetics[1]/Ras/inact-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/inact-GEF /kinetics/chain/kinetics[1]/Ras/inact-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[1]/Ras/GEF* MM_PRD pA addmsg /kinetics/chain/kinetics[1]/Ras/dephosph-GEF /kinetics/chain/kinetics[1]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[1]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[1]/Ras/GEF* REAC eA B addmsg /kinetics/chain/kinetics/Ras/GEF*/diff /kinetics/chain/kinetics[1]/Ras/GEF* REAC B A addmsg /kinetics/chain/kinetics[1]/Ras/GEF*/diff /kinetics/chain/kinetics[1]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[1]/Ras/GEF* /kinetics/chain/kinetics[1]/Ras/GEF*/GEF*-act-ras ENZYME n addmsg /kinetics/chain/kinetics[1]/Ras/GDP-Ras /kinetics/chain/kinetics[1]/Ras/GEF*/GEF*-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/GEF* /kinetics/chain/kinetics[1]/Ras/GEF*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/GEF* /kinetics/chain/kinetics[1]/Ras/GEF*/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ras-act-craf /kinetics/chain/kinetics[1]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[1]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[1]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[1]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[1]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[1]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[1]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[1]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[1]/Ras/GTP-Ras REAC sA B addmsg /kinetics/chain/kinetics[1]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[1]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[1]/Ras-act-unphosph-raf /kinetics/chain/kinetics[1]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics/Ras/GTP-Ras/diff /kinetics/chain/kinetics[1]/Ras/GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[1]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[1]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[1]/Ras/GTP-Ras /kinetics/chain/kinetics[1]/Ras/GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/GTP-Ras /kinetics/chain/kinetics[1]/Ras/GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[1]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[1]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[1]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[1]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[1]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[1]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[1]/Ras/GDP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[1]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[1]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics/Ras/GDP-Ras/diff /kinetics/chain/kinetics[1]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[1]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[1]/Ras/GDP-Ras REAC A B addmsg /kinetics/chain/kinetics[1]/Ras/GDP-Ras /kinetics/chain/kinetics[1]/Ras/GDP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/GDP-Ras /kinetics/chain/kinetics[1]/Ras/GDP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ras/GTP-Ras /kinetics/chain/kinetics[1]/Ras/Ras-intrinsic-GTPase SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/GDP-Ras /kinetics/chain/kinetics[1]/Ras/Ras-intrinsic-GTPase PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ras/GAP* /kinetics/chain/kinetics[1]/Ras/dephosph-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/GAP /kinetics/chain/kinetics[1]/Ras/dephosph-GAP PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[1]/Ras/GAP* MM_PRD pA addmsg /kinetics/chain/kinetics[1]/Ras/dephosph-GAP /kinetics/chain/kinetics[1]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics/Ras/GAP*/diff /kinetics/chain/kinetics[1]/Ras/GAP* REAC B A addmsg /kinetics/chain/kinetics[1]/Ras/GAP*/diff /kinetics/chain/kinetics[1]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[1]/Ras/GAP* /kinetics/chain/kinetics[1]/Ras/GAP*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/GAP* /kinetics/chain/kinetics[1]/Ras/GAP*/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[1]/Ras/GAP REAC sA B addmsg /kinetics/chain/kinetics[1]/Ras/dephosph-GAP /kinetics/chain/kinetics[1]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[1]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[1]/Ras/GAP REAC eA B addmsg /kinetics/chain/kinetics/Ras/GAP/diff /kinetics/chain/kinetics[1]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[1]/Ras/GAP/diff /kinetics/chain/kinetics[1]/Ras/GAP REAC A B addmsg /kinetics/chain/kinetics[1]/Ras/GTP-Ras /kinetics/chain/kinetics[1]/Ras/GAP/GAP-inact-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/GAP /kinetics/chain/kinetics[1]/Ras/GAP/GAP-inact-ras ENZYME n addmsg /kinetics/chain/kinetics[1]/Ras/GAP /kinetics/chain/kinetics[1]/Ras/GAP/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/GAP /kinetics/chain/kinetics[1]/Ras/GAP/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ras/inact-GEF /kinetics/chain/kinetics[1]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/CaM-GEF /kinetics/chain/kinetics[1]/Ras/CaM-bind-GEF PRODUCT n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca4 /kinetics/chain/kinetics[1]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[1]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[1]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[1]/Ras/CaM-GEF REAC eA B addmsg /kinetics/chain/kinetics/Ras/CaM-GEF/diff /kinetics/chain/kinetics[1]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[1]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[1]/Ras/CaM-GEF REAC A B addmsg /kinetics/chain/kinetics[1]/Ras/GDP-Ras /kinetics/chain/kinetics[1]/Ras/CaM-GEF/CaM-GEF-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ras/CaM-GEF /kinetics/chain/kinetics[1]/Ras/CaM-GEF/CaM-GEF-act-ras ENZYME n addmsg /kinetics/chain/kinetics[1]/Ras/CaM-GEF /kinetics/chain/kinetics[1]/Ras/CaM-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/CaM-GEF /kinetics/chain/kinetics[1]/Ras/CaM-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[1]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics/CaM/CaM/diff /kinetics/chain/kinetics[1]/CaM/CaM REAC B A addmsg /kinetics/chain/kinetics[1]/CaM/CaM/diff /kinetics/chain/kinetics[1]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM /kinetics/chain/kinetics[1]/CaM/CaM/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/CaM/CaM /kinetics/chain/kinetics[1]/CaM/CaM/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca3 /kinetics/chain/kinetics[1]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca4 /kinetics/chain/kinetics[1]/CaM/CaM-Ca3-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ca /kinetics/chain/kinetics[1]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[1]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[1]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[1]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[1]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca3 /kinetics/chain/kinetics[1]/CaM/CaM-Ca3/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca3 /kinetics/chain/kinetics[1]/CaM/CaM-Ca3/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[1]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[1]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[1]/PKM/trigger_PKM /kinetics/chain/kinetics[1]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[1]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[1]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca4 /kinetics/chain/kinetics[1]/CaM/CaM-Ca4/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca4 /kinetics/chain/kinetics[1]/CaM/CaM-Ca4/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/CaM/CaM /kinetics/chain/kinetics[1]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca /kinetics/chain/kinetics[1]/CaM/CaM-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ca /kinetics/chain/kinetics[1]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[1]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[1]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[1]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[1]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca2 /kinetics/chain/kinetics[1]/CaM/CaM-Ca2/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca2 /kinetics/chain/kinetics[1]/CaM/CaM-Ca2/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca3 /kinetics/chain/kinetics[1]/CaM/CaM-Ca2-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca2 /kinetics/chain/kinetics[1]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ca /kinetics/chain/kinetics[1]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca2 /kinetics/chain/kinetics[1]/CaM/CaM-Ca-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca /kinetics/chain/kinetics[1]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/Ca /kinetics/chain/kinetics[1]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[1]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[1]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics/CaM/CaM-Ca/diff /kinetics/chain/kinetics[1]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[1]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca /kinetics/chain/kinetics[1]/CaM/CaM-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca /kinetics/chain/kinetics[1]/CaM/CaM-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[1]/Ca REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[1]/Ca REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[1]/Ca REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[1]/Ca REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[1]/Ca REAC A B addmsg /kinetics/chain/kinetics[1]/Ca_diff /kinetics/chain/kinetics[1]/Ca REAC B A addmsg /kinetics/chain/kinetics/Ca/diff /kinetics/chain/kinetics[1]/Ca REAC B A addmsg /kinetics/chain/kinetics[1]/Ca/diff /kinetics/chain/kinetics[1]/Ca REAC A B addmsg /kinetics/chain/kinetics[1]/Ca /kinetics/chain/kinetics[1]/Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ca /kinetics/chain/kinetics[1]/Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1 /kinetics/chain/kinetics[1]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[1]/Ras-act-unphosph-raf PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ras/GTP-Ras /kinetics/chain/kinetics[1]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKM/trigger_PKM /kinetics/chain/kinetics[1]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics/PKM/Ca_detector/diff /kinetics/chain/kinetics[1]/PKM/Ca_detector REAC B A addmsg /kinetics/chain/kinetics[1]/PKM/Ca_detector/diff /kinetics/chain/kinetics[1]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[1]/PKM/Ca_detector /kinetics/chain/kinetics[1]/PKM/Ca_detector/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKM/Ca_detector /kinetics/chain/kinetics[1]/PKM/Ca_detector/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[1]/PKM/PKM_synthesis REAC eA B addmsg /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[1]/PKM/PKM_synthesis MM_PRD pA addmsg /kinetics/chain/kinetics[1]/PKM/turn_off_activator /kinetics/chain/kinetics[1]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[1]/PKM/PKM_synthesis REAC B A addmsg /kinetics/chain/kinetics[1]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[1]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[1]/PKM/PKM_synthesis /kinetics/chain/kinetics[1]/PKM/PKM_synthesis/kenz ENZYME n addmsg /kinetics/chain/kinetics[1]/PKM/AA_pool /kinetics/chain/kinetics[1]/PKM/PKM_synthesis/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKM/PKM_synthesis /kinetics/chain/kinetics[1]/PKM/PKM_synthesis/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKM/PKM_synthesis /kinetics/chain/kinetics[1]/PKM/PKM_synthesis/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[1]/PKM/AA_pool REAC sA B addmsg /kinetics/chain/kinetics[1]/PKC/PKM-zeta /kinetics/chain/kinetics[1]/PKM/PKM_degradation SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKM/degraded_PKM /kinetics/chain/kinetics[1]/PKM/PKM_degradation PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKM/PKM_degradation /kinetics/chain/kinetics[1]/PKM/degraded_PKM REAC B A addmsg /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex REAC eA B addmsg /kinetics/chain/kinetics[1]/PKM/trigger_PKM /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex REAC A B addmsg /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex/kenz ENZYME n addmsg /kinetics/chain/kinetics[1]/PKM/PKM_activator /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[1]/PKM/PKM_activator REAC sA B addmsg /kinetics/chain/kinetics[1]/PKM/turn_off_activator /kinetics/chain/kinetics[1]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics/PKM/PKM_activator/diff /kinetics/chain/kinetics[1]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[1]/PKM/PKM_activator/diff /kinetics/chain/kinetics[1]/PKM/PKM_activator REAC A B addmsg /kinetics/chain/kinetics[1]/PKM/PKM_activator /kinetics/chain/kinetics[1]/PKM/PKM_activator/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKM/PKM_activator /kinetics/chain/kinetics[1]/PKM/PKM_activator/diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/PKM/PKM_synthesis /kinetics/chain/kinetics[1]/PKM/turn_off_activator SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKM/PKM_activator /kinetics/chain/kinetics[1]/PKM/turn_off_activator PRODUCT n addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca4 /kinetics/chain/kinetics[1]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKM/Ca_detector /kinetics/chain/kinetics[1]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex /kinetics/chain/kinetics[1]/PKM/trigger_PKM PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ca_diff /kinetics/chain/kinetics[1]/Ca_input REAC A B addmsg /kinetics/chain/kinetics[1]/Ca /kinetics/chain/kinetics[1]/Ca_diff PRODUCT n addmsg /kinetics/chain/kinetics[1]/Ca_input /kinetics/chain/kinetics[1]/Ca_diff SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[2]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[2]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[2]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[2]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[2]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[2]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca /kinetics/chain/kinetics[2]/PKC/PKC-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca /kinetics/chain/kinetics[2]/PKC/PKC-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca /kinetics/chain/kinetics[2]/PKC/PKC-act-by-Ca PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic /kinetics/chain/kinetics[2]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ca /kinetics/chain/kinetics[2]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca /kinetics/chain/kinetics[2]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[2]/PKC/PKC-act-by-DAG PRODUCT n addmsg /kinetics/chain/kinetics[2]/DAG /kinetics/chain/kinetics[2]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca /kinetics/chain/kinetics[2]/PKC/PKC-Ca-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[2]/PKC/PKC-Ca-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[2]/PKC/PKC-DAG-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[2]/PKC/PKC-DAG-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[2]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[2]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[2]/PKC/PKC-Ca-memb* REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[2]/PKC/PKC-Ca-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[2]/PKC/PKC-Ca-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[2]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[1]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[2]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[2]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[2]/PKC/PKC-DAG-memb* REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[2]/PKC/PKC-DAG-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[2]/PKC/PKC-DAG-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[2]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-DAG /kinetics/chain/kinetics[2]/PKC/PKC-n-DAG PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic /kinetics/chain/kinetics[2]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/DAG /kinetics/chain/kinetics[2]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-n-DAG /kinetics/chain/kinetics[2]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[1]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[2]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[2]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[2]/PKC/PKC-DAG REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKC-DAG /kinetics/chain/kinetics[2]/PKC/PKC-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-DAG /kinetics/chain/kinetics[2]/PKC/PKC-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKC-n-DAG /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic REAC B A addmsg /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[2]/PKC/PKM-zeta MM_PRD pA addmsg /kinetics/chain/kinetics[2]/PKM/PKM_degradation /kinetics/chain/kinetics[2]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[1]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[2]/PKC/PKM-zeta REAC B A addmsg /kinetics/chain/kinetics[2]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[2]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKM-zeta /kinetics/chain/kinetics[2]/PKC/PKM-zeta/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKM-zeta /kinetics/chain/kinetics[2]/PKC/PKM-zeta/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[2]/DAG REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKC-n-DAG /kinetics/chain/kinetics[2]/DAG REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[2]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[2]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[2]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[2]/PKC/PKM-zeta /kinetics/chain/kinetics[2]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[2]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[2]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[2]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[2]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[2]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[2]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[2]/PKC-active /kinetics/chain/kinetics[2]/PKC-active/PKC-act-raf ENZYME n addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1 /kinetics/chain/kinetics[2]/PKC-active/PKC-act-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC-active /kinetics/chain/kinetics[2]/PKC-active/PKC-inact-GAP ENZYME n addmsg /kinetics/chain/kinetics[2]/Ras/GAP /kinetics/chain/kinetics[2]/PKC-active/PKC-inact-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC-active /kinetics/chain/kinetics[2]/PKC-active/PKC-act-GEF ENZYME n addmsg /kinetics/chain/kinetics[2]/Ras/inact-GEF /kinetics/chain/kinetics[2]/PKC-active/PKC-act-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[2]/MAPK* REAC eA B addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[2]/MAPK* MM_PRD pA addmsg /kinetics/chain/kinetics[2]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[2]/MAPK* REAC sA B addmsg /kinetics/chain/kinetics[1]/MAPK*/diff /kinetics/chain/kinetics[2]/MAPK* REAC B A addmsg /kinetics/chain/kinetics[2]/MAPK*/diff /kinetics/chain/kinetics[2]/MAPK* REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK* /kinetics/chain/kinetics[2]/MAPK*/MAPK*-feedback ENZYME n addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1* /kinetics/chain/kinetics[2]/MAPK*/MAPK*-feedback SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK* /kinetics/chain/kinetics[2]/MAPK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK* /kinetics/chain/kinetics[2]/MAPK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[2]/MAPK/craf-1 REAC sA B addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[2]/MAPK/craf-1 MM_PRD pA addmsg /kinetics/chain/kinetics[2]/Ras-act-unphosph-raf /kinetics/chain/kinetics[2]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1/diff /kinetics/chain/kinetics[2]/MAPK/craf-1 REAC B A addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1/diff /kinetics/chain/kinetics[2]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1 /kinetics/chain/kinetics[2]/MAPK/craf-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1 /kinetics/chain/kinetics[2]/MAPK/craf-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[2]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[2]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[2]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[2]/Ras-act-craf /kinetics/chain/kinetics[2]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[2]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[2]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1*/diff /kinetics/chain/kinetics[2]/MAPK/craf-1* REAC B A addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1*/diff /kinetics/chain/kinetics[2]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1* /kinetics/chain/kinetics[2]/MAPK/craf-1*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1* /kinetics/chain/kinetics[2]/MAPK/craf-1*/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[2]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[2]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[2]/MAPK/MAPKK MM_PRD pA addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK/diff /kinetics/chain/kinetics[2]/MAPK/MAPKK REAC B A addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK/diff /kinetics/chain/kinetics[2]/MAPK/MAPKK REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK /kinetics/chain/kinetics[2]/MAPK/MAPKK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK /kinetics/chain/kinetics[2]/MAPK/MAPKK/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[2]/MAPK/MAPK REAC sA B addmsg /kinetics/chain/kinetics[2]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[2]/MAPK/MAPK MM_PRD pA addmsg /kinetics/chain/kinetics[1]/MAPK/MAPK/diff /kinetics/chain/kinetics[2]/MAPK/MAPK REAC B A addmsg /kinetics/chain/kinetics[2]/MAPK/MAPK/diff /kinetics/chain/kinetics[2]/MAPK/MAPK REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK/MAPK /kinetics/chain/kinetics[2]/MAPK/MAPK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPK /kinetics/chain/kinetics[2]/MAPK/MAPK/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[2]/MAPK/craf-1** MM_PRD pA addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[2]/MAPK/craf-1** REAC sA B addmsg /kinetics/chain/kinetics[1]/MAPK/craf-1**/diff /kinetics/chain/kinetics[2]/MAPK/craf-1** REAC B A addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1**/diff /kinetics/chain/kinetics[2]/MAPK/craf-1** REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1** /kinetics/chain/kinetics[2]/MAPK/craf-1**/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1** /kinetics/chain/kinetics[2]/MAPK/craf-1**/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[2]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[2]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[1]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr REAC B A addmsg /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[2]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[2]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[2]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[2]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[2]/MAPK/MAPKK* REAC sA B addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[2]/MAPK/MAPKK* REAC B A addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[2]/MAPK/MAPKK* REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK/MAPK /kinetics/chain/kinetics[2]/MAPK/MAPKK*/MAPKKtyr SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK* /kinetics/chain/kinetics[2]/MAPK/MAPKK*/MAPKKtyr ENZYME n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr /kinetics/chain/kinetics[2]/MAPK/MAPKK*/MAPKKthr SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK* /kinetics/chain/kinetics[2]/MAPK/MAPKK*/MAPKKthr ENZYME n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK* /kinetics/chain/kinetics[2]/MAPK/MAPKK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK* /kinetics/chain/kinetics[2]/MAPK/MAPKK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[1]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser REAC B A addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[2]/Ras-act-unphosph-raf /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[1]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[2]/Ras-act-craf /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[1]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[2]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[2]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[2]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[1]/MKP-1/diff /kinetics/chain/kinetics[2]/MKP-1 REAC B A addmsg /kinetics/chain/kinetics[2]/MKP-1/diff /kinetics/chain/kinetics[2]/MKP-1 REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr /kinetics/chain/kinetics[2]/MKP-1/MKP1-tyr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MKP-1 /kinetics/chain/kinetics[2]/MKP-1/MKP1-tyr-deph ENZYME n addmsg /kinetics/chain/kinetics[2]/MAPK* /kinetics/chain/kinetics[2]/MKP-1/MKP1-thr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MKP-1 /kinetics/chain/kinetics[2]/MKP-1/MKP1-thr-deph ENZYME n addmsg /kinetics/chain/kinetics[2]/MKP-1 /kinetics/chain/kinetics[2]/MKP-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MKP-1 /kinetics/chain/kinetics[2]/MKP-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1* /kinetics/chain/kinetics[2]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[2]/Ras-act-craf PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ras/GTP-Ras /kinetics/chain/kinetics[2]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[2]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[2]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[2]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[2]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[1]/PPhosphatase2A/diff /kinetics/chain/kinetics[2]/PPhosphatase2A REAC B A addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/diff /kinetics/chain/kinetics[2]/PPhosphatase2A REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1* /kinetics/chain/kinetics[2]/PPhosphatase2A/craf-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A /kinetics/chain/kinetics[2]/PPhosphatase2A/craf-deph ENZYME n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK* /kinetics/chain/kinetics[2]/PPhosphatase2A/MAPKK-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A /kinetics/chain/kinetics[2]/PPhosphatase2A/MAPKK-deph ENZYME n addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser /kinetics/chain/kinetics[2]/PPhosphatase2A/MAPKK-deph-ser SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A /kinetics/chain/kinetics[2]/PPhosphatase2A/MAPKK-deph-ser ENZYME n addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1** /kinetics/chain/kinetics[2]/PPhosphatase2A/craf**-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A /kinetics/chain/kinetics[2]/PPhosphatase2A/craf**-deph ENZYME n addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A /kinetics/chain/kinetics[2]/PPhosphatase2A/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A /kinetics/chain/kinetics[2]/PPhosphatase2A/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ras/inact-GEF /kinetics/chain/kinetics[2]/Ras/dephosph-GEF PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ras/GEF* /kinetics/chain/kinetics[2]/Ras/dephosph-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[2]/Ras/inact-GEF REAC sA B addmsg /kinetics/chain/kinetics[2]/Ras/dephosph-GEF /kinetics/chain/kinetics[2]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[2]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[2]/Ras/inact-GEF REAC eA B addmsg /kinetics/chain/kinetics[2]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[2]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[1]/Ras/inact-GEF/diff /kinetics/chain/kinetics[2]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[2]/Ras/inact-GEF/diff /kinetics/chain/kinetics[2]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[2]/Ras/inact-GEF /kinetics/chain/kinetics[2]/Ras/inact-GEF/basal_GEF_activity ENZYME n addmsg /kinetics/chain/kinetics[2]/Ras/GDP-Ras /kinetics/chain/kinetics[2]/Ras/inact-GEF/basal_GEF_activity SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/inact-GEF /kinetics/chain/kinetics[2]/Ras/inact-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/inact-GEF /kinetics/chain/kinetics[2]/Ras/inact-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[2]/Ras/GEF* MM_PRD pA addmsg /kinetics/chain/kinetics[2]/Ras/dephosph-GEF /kinetics/chain/kinetics[2]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[2]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[2]/Ras/GEF* REAC eA B addmsg /kinetics/chain/kinetics[1]/Ras/GEF*/diff /kinetics/chain/kinetics[2]/Ras/GEF* REAC B A addmsg /kinetics/chain/kinetics[2]/Ras/GEF*/diff /kinetics/chain/kinetics[2]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[2]/Ras/GEF* /kinetics/chain/kinetics[2]/Ras/GEF*/GEF*-act-ras ENZYME n addmsg /kinetics/chain/kinetics[2]/Ras/GDP-Ras /kinetics/chain/kinetics[2]/Ras/GEF*/GEF*-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/GEF* /kinetics/chain/kinetics[2]/Ras/GEF*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/GEF* /kinetics/chain/kinetics[2]/Ras/GEF*/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ras-act-craf /kinetics/chain/kinetics[2]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[2]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[2]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[2]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[2]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[2]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[2]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[2]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[2]/Ras/GTP-Ras REAC sA B addmsg /kinetics/chain/kinetics[2]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[2]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[2]/Ras-act-unphosph-raf /kinetics/chain/kinetics[2]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[1]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[2]/Ras/GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[2]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[2]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[2]/Ras/GTP-Ras /kinetics/chain/kinetics[2]/Ras/GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/GTP-Ras /kinetics/chain/kinetics[2]/Ras/GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[2]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[2]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[2]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[2]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[2]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[2]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[2]/Ras/GDP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[2]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[2]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[1]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[2]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[2]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[2]/Ras/GDP-Ras REAC A B addmsg /kinetics/chain/kinetics[2]/Ras/GDP-Ras /kinetics/chain/kinetics[2]/Ras/GDP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/GDP-Ras /kinetics/chain/kinetics[2]/Ras/GDP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ras/GTP-Ras /kinetics/chain/kinetics[2]/Ras/Ras-intrinsic-GTPase SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/GDP-Ras /kinetics/chain/kinetics[2]/Ras/Ras-intrinsic-GTPase PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ras/GAP* /kinetics/chain/kinetics[2]/Ras/dephosph-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/GAP /kinetics/chain/kinetics[2]/Ras/dephosph-GAP PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[2]/Ras/GAP* MM_PRD pA addmsg /kinetics/chain/kinetics[2]/Ras/dephosph-GAP /kinetics/chain/kinetics[2]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[1]/Ras/GAP*/diff /kinetics/chain/kinetics[2]/Ras/GAP* REAC B A addmsg /kinetics/chain/kinetics[2]/Ras/GAP*/diff /kinetics/chain/kinetics[2]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[2]/Ras/GAP* /kinetics/chain/kinetics[2]/Ras/GAP*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/GAP* /kinetics/chain/kinetics[2]/Ras/GAP*/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[2]/Ras/GAP REAC sA B addmsg /kinetics/chain/kinetics[2]/Ras/dephosph-GAP /kinetics/chain/kinetics[2]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[2]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[2]/Ras/GAP REAC eA B addmsg /kinetics/chain/kinetics[1]/Ras/GAP/diff /kinetics/chain/kinetics[2]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[2]/Ras/GAP/diff /kinetics/chain/kinetics[2]/Ras/GAP REAC A B addmsg /kinetics/chain/kinetics[2]/Ras/GTP-Ras /kinetics/chain/kinetics[2]/Ras/GAP/GAP-inact-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/GAP /kinetics/chain/kinetics[2]/Ras/GAP/GAP-inact-ras ENZYME n addmsg /kinetics/chain/kinetics[2]/Ras/GAP /kinetics/chain/kinetics[2]/Ras/GAP/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/GAP /kinetics/chain/kinetics[2]/Ras/GAP/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ras/inact-GEF /kinetics/chain/kinetics[2]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/CaM-GEF /kinetics/chain/kinetics[2]/Ras/CaM-bind-GEF PRODUCT n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca4 /kinetics/chain/kinetics[2]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[2]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[2]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[2]/Ras/CaM-GEF REAC eA B addmsg /kinetics/chain/kinetics[1]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[2]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[2]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[2]/Ras/CaM-GEF REAC A B addmsg /kinetics/chain/kinetics[2]/Ras/GDP-Ras /kinetics/chain/kinetics[2]/Ras/CaM-GEF/CaM-GEF-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ras/CaM-GEF /kinetics/chain/kinetics[2]/Ras/CaM-GEF/CaM-GEF-act-ras ENZYME n addmsg /kinetics/chain/kinetics[2]/Ras/CaM-GEF /kinetics/chain/kinetics[2]/Ras/CaM-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/CaM-GEF /kinetics/chain/kinetics[2]/Ras/CaM-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[2]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM/diff /kinetics/chain/kinetics[2]/CaM/CaM REAC B A addmsg /kinetics/chain/kinetics[2]/CaM/CaM/diff /kinetics/chain/kinetics[2]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM /kinetics/chain/kinetics[2]/CaM/CaM/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/CaM/CaM /kinetics/chain/kinetics[2]/CaM/CaM/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca3 /kinetics/chain/kinetics[2]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca4 /kinetics/chain/kinetics[2]/CaM/CaM-Ca3-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ca /kinetics/chain/kinetics[2]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[2]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[2]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[2]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[2]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca3 /kinetics/chain/kinetics[2]/CaM/CaM-Ca3/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca3 /kinetics/chain/kinetics[2]/CaM/CaM-Ca3/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[2]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[2]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[2]/PKM/trigger_PKM /kinetics/chain/kinetics[2]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[2]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[2]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca4 /kinetics/chain/kinetics[2]/CaM/CaM-Ca4/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca4 /kinetics/chain/kinetics[2]/CaM/CaM-Ca4/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/CaM/CaM /kinetics/chain/kinetics[2]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca /kinetics/chain/kinetics[2]/CaM/CaM-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ca /kinetics/chain/kinetics[2]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[2]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[2]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[2]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[2]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca2 /kinetics/chain/kinetics[2]/CaM/CaM-Ca2/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca2 /kinetics/chain/kinetics[2]/CaM/CaM-Ca2/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca3 /kinetics/chain/kinetics[2]/CaM/CaM-Ca2-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca2 /kinetics/chain/kinetics[2]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ca /kinetics/chain/kinetics[2]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca2 /kinetics/chain/kinetics[2]/CaM/CaM-Ca-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca /kinetics/chain/kinetics[2]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/Ca /kinetics/chain/kinetics[2]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[2]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[2]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[1]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[2]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[2]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca /kinetics/chain/kinetics[2]/CaM/CaM-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca /kinetics/chain/kinetics[2]/CaM/CaM-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[2]/Ca REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[2]/Ca REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[2]/Ca REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[2]/Ca REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[2]/Ca REAC A B addmsg /kinetics/chain/kinetics[2]/Ca_diff /kinetics/chain/kinetics[2]/Ca REAC B A addmsg /kinetics/chain/kinetics[1]/Ca/diff /kinetics/chain/kinetics[2]/Ca REAC B A addmsg /kinetics/chain/kinetics[2]/Ca/diff /kinetics/chain/kinetics[2]/Ca REAC A B addmsg /kinetics/chain/kinetics[2]/Ca /kinetics/chain/kinetics[2]/Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ca /kinetics/chain/kinetics[2]/Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1 /kinetics/chain/kinetics[2]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[2]/Ras-act-unphosph-raf PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ras/GTP-Ras /kinetics/chain/kinetics[2]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKM/trigger_PKM /kinetics/chain/kinetics[2]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[1]/PKM/Ca_detector/diff /kinetics/chain/kinetics[2]/PKM/Ca_detector REAC B A addmsg /kinetics/chain/kinetics[2]/PKM/Ca_detector/diff /kinetics/chain/kinetics[2]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[2]/PKM/Ca_detector /kinetics/chain/kinetics[2]/PKM/Ca_detector/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKM/Ca_detector /kinetics/chain/kinetics[2]/PKM/Ca_detector/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[2]/PKM/PKM_synthesis REAC eA B addmsg /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[2]/PKM/PKM_synthesis MM_PRD pA addmsg /kinetics/chain/kinetics[2]/PKM/turn_off_activator /kinetics/chain/kinetics[2]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[1]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[2]/PKM/PKM_synthesis REAC B A addmsg /kinetics/chain/kinetics[2]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[2]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[2]/PKM/PKM_synthesis /kinetics/chain/kinetics[2]/PKM/PKM_synthesis/kenz ENZYME n addmsg /kinetics/chain/kinetics[2]/PKM/AA_pool /kinetics/chain/kinetics[2]/PKM/PKM_synthesis/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKM/PKM_synthesis /kinetics/chain/kinetics[2]/PKM/PKM_synthesis/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKM/PKM_synthesis /kinetics/chain/kinetics[2]/PKM/PKM_synthesis/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[2]/PKM/AA_pool REAC sA B addmsg /kinetics/chain/kinetics[2]/PKC/PKM-zeta /kinetics/chain/kinetics[2]/PKM/PKM_degradation SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKM/degraded_PKM /kinetics/chain/kinetics[2]/PKM/PKM_degradation PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKM/PKM_degradation /kinetics/chain/kinetics[2]/PKM/degraded_PKM REAC B A addmsg /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex REAC eA B addmsg /kinetics/chain/kinetics[2]/PKM/trigger_PKM /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[1]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex REAC A B addmsg /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex/kenz ENZYME n addmsg /kinetics/chain/kinetics[2]/PKM/PKM_activator /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[2]/PKM/PKM_activator REAC sA B addmsg /kinetics/chain/kinetics[2]/PKM/turn_off_activator /kinetics/chain/kinetics[2]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[1]/PKM/PKM_activator/diff /kinetics/chain/kinetics[2]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[2]/PKM/PKM_activator/diff /kinetics/chain/kinetics[2]/PKM/PKM_activator REAC A B addmsg /kinetics/chain/kinetics[2]/PKM/PKM_activator /kinetics/chain/kinetics[2]/PKM/PKM_activator/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKM/PKM_activator /kinetics/chain/kinetics[2]/PKM/PKM_activator/diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/PKM/PKM_synthesis /kinetics/chain/kinetics[2]/PKM/turn_off_activator SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKM/PKM_activator /kinetics/chain/kinetics[2]/PKM/turn_off_activator PRODUCT n addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca4 /kinetics/chain/kinetics[2]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKM/Ca_detector /kinetics/chain/kinetics[2]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex /kinetics/chain/kinetics[2]/PKM/trigger_PKM PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ca_diff /kinetics/chain/kinetics[2]/Ca_input REAC A B addmsg /kinetics/chain/kinetics[2]/Ca /kinetics/chain/kinetics[2]/Ca_diff PRODUCT n addmsg /kinetics/chain/kinetics[2]/Ca_input /kinetics/chain/kinetics[2]/Ca_diff SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[3]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[3]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[3]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[3]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[3]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[3]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca /kinetics/chain/kinetics[3]/PKC/PKC-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca /kinetics/chain/kinetics[3]/PKC/PKC-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca /kinetics/chain/kinetics[3]/PKC/PKC-act-by-Ca PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic /kinetics/chain/kinetics[3]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ca /kinetics/chain/kinetics[3]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca /kinetics/chain/kinetics[3]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[3]/PKC/PKC-act-by-DAG PRODUCT n addmsg /kinetics/chain/kinetics[3]/DAG /kinetics/chain/kinetics[3]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca /kinetics/chain/kinetics[3]/PKC/PKC-Ca-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[3]/PKC/PKC-Ca-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[3]/PKC/PKC-DAG-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[3]/PKC/PKC-DAG-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[3]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[3]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[3]/PKC/PKC-Ca-memb* REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[3]/PKC/PKC-Ca-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[3]/PKC/PKC-Ca-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[3]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[2]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[3]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[3]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[3]/PKC/PKC-DAG-memb* REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[3]/PKC/PKC-DAG-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[3]/PKC/PKC-DAG-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[3]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-DAG /kinetics/chain/kinetics[3]/PKC/PKC-n-DAG PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic /kinetics/chain/kinetics[3]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/DAG /kinetics/chain/kinetics[3]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-n-DAG /kinetics/chain/kinetics[3]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[2]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[3]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[3]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[3]/PKC/PKC-DAG REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKC-DAG /kinetics/chain/kinetics[3]/PKC/PKC-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-DAG /kinetics/chain/kinetics[3]/PKC/PKC-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKC-n-DAG /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic REAC B A addmsg /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[3]/PKC/PKM-zeta MM_PRD pA addmsg /kinetics/chain/kinetics[3]/PKM/PKM_degradation /kinetics/chain/kinetics[3]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[2]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[3]/PKC/PKM-zeta REAC B A addmsg /kinetics/chain/kinetics[3]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[3]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKM-zeta /kinetics/chain/kinetics[3]/PKC/PKM-zeta/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKM-zeta /kinetics/chain/kinetics[3]/PKC/PKM-zeta/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[3]/DAG REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKC-n-DAG /kinetics/chain/kinetics[3]/DAG REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[3]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[3]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[3]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[3]/PKC/PKM-zeta /kinetics/chain/kinetics[3]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[3]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[3]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[3]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[3]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[3]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[3]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[3]/PKC-active /kinetics/chain/kinetics[3]/PKC-active/PKC-act-raf ENZYME n addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1 /kinetics/chain/kinetics[3]/PKC-active/PKC-act-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC-active /kinetics/chain/kinetics[3]/PKC-active/PKC-inact-GAP ENZYME n addmsg /kinetics/chain/kinetics[3]/Ras/GAP /kinetics/chain/kinetics[3]/PKC-active/PKC-inact-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC-active /kinetics/chain/kinetics[3]/PKC-active/PKC-act-GEF ENZYME n addmsg /kinetics/chain/kinetics[3]/Ras/inact-GEF /kinetics/chain/kinetics[3]/PKC-active/PKC-act-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[3]/MAPK* REAC eA B addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[3]/MAPK* MM_PRD pA addmsg /kinetics/chain/kinetics[3]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[3]/MAPK* REAC sA B addmsg /kinetics/chain/kinetics[2]/MAPK*/diff /kinetics/chain/kinetics[3]/MAPK* REAC B A addmsg /kinetics/chain/kinetics[3]/MAPK*/diff /kinetics/chain/kinetics[3]/MAPK* REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK* /kinetics/chain/kinetics[3]/MAPK*/MAPK*-feedback ENZYME n addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1* /kinetics/chain/kinetics[3]/MAPK*/MAPK*-feedback SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK* /kinetics/chain/kinetics[3]/MAPK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK* /kinetics/chain/kinetics[3]/MAPK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[3]/MAPK/craf-1 REAC sA B addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[3]/MAPK/craf-1 MM_PRD pA addmsg /kinetics/chain/kinetics[3]/Ras-act-unphosph-raf /kinetics/chain/kinetics[3]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1/diff /kinetics/chain/kinetics[3]/MAPK/craf-1 REAC B A addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1/diff /kinetics/chain/kinetics[3]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1 /kinetics/chain/kinetics[3]/MAPK/craf-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1 /kinetics/chain/kinetics[3]/MAPK/craf-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[3]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[3]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[3]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[3]/Ras-act-craf /kinetics/chain/kinetics[3]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[3]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[3]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1*/diff /kinetics/chain/kinetics[3]/MAPK/craf-1* REAC B A addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1*/diff /kinetics/chain/kinetics[3]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1* /kinetics/chain/kinetics[3]/MAPK/craf-1*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1* /kinetics/chain/kinetics[3]/MAPK/craf-1*/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[3]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[3]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[3]/MAPK/MAPKK MM_PRD pA addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK/diff /kinetics/chain/kinetics[3]/MAPK/MAPKK REAC B A addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK/diff /kinetics/chain/kinetics[3]/MAPK/MAPKK REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK /kinetics/chain/kinetics[3]/MAPK/MAPKK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK /kinetics/chain/kinetics[3]/MAPK/MAPKK/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[3]/MAPK/MAPK REAC sA B addmsg /kinetics/chain/kinetics[3]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[3]/MAPK/MAPK MM_PRD pA addmsg /kinetics/chain/kinetics[2]/MAPK/MAPK/diff /kinetics/chain/kinetics[3]/MAPK/MAPK REAC B A addmsg /kinetics/chain/kinetics[3]/MAPK/MAPK/diff /kinetics/chain/kinetics[3]/MAPK/MAPK REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK/MAPK /kinetics/chain/kinetics[3]/MAPK/MAPK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPK /kinetics/chain/kinetics[3]/MAPK/MAPK/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[3]/MAPK/craf-1** MM_PRD pA addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[3]/MAPK/craf-1** REAC sA B addmsg /kinetics/chain/kinetics[2]/MAPK/craf-1**/diff /kinetics/chain/kinetics[3]/MAPK/craf-1** REAC B A addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1**/diff /kinetics/chain/kinetics[3]/MAPK/craf-1** REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1** /kinetics/chain/kinetics[3]/MAPK/craf-1**/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1** /kinetics/chain/kinetics[3]/MAPK/craf-1**/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[3]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[3]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[2]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr REAC B A addmsg /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[3]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[3]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[3]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[3]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[3]/MAPK/MAPKK* REAC sA B addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[3]/MAPK/MAPKK* REAC B A addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[3]/MAPK/MAPKK* REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK/MAPK /kinetics/chain/kinetics[3]/MAPK/MAPKK*/MAPKKtyr SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK* /kinetics/chain/kinetics[3]/MAPK/MAPKK*/MAPKKtyr ENZYME n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr /kinetics/chain/kinetics[3]/MAPK/MAPKK*/MAPKKthr SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK* /kinetics/chain/kinetics[3]/MAPK/MAPKK*/MAPKKthr ENZYME n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK* /kinetics/chain/kinetics[3]/MAPK/MAPKK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK* /kinetics/chain/kinetics[3]/MAPK/MAPKK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[2]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser REAC B A addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[3]/Ras-act-unphosph-raf /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[2]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[3]/Ras-act-craf /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[2]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[3]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[3]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[3]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[2]/MKP-1/diff /kinetics/chain/kinetics[3]/MKP-1 REAC B A addmsg /kinetics/chain/kinetics[3]/MKP-1/diff /kinetics/chain/kinetics[3]/MKP-1 REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr /kinetics/chain/kinetics[3]/MKP-1/MKP1-tyr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MKP-1 /kinetics/chain/kinetics[3]/MKP-1/MKP1-tyr-deph ENZYME n addmsg /kinetics/chain/kinetics[3]/MAPK* /kinetics/chain/kinetics[3]/MKP-1/MKP1-thr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MKP-1 /kinetics/chain/kinetics[3]/MKP-1/MKP1-thr-deph ENZYME n addmsg /kinetics/chain/kinetics[3]/MKP-1 /kinetics/chain/kinetics[3]/MKP-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MKP-1 /kinetics/chain/kinetics[3]/MKP-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1* /kinetics/chain/kinetics[3]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[3]/Ras-act-craf PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ras/GTP-Ras /kinetics/chain/kinetics[3]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[3]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[3]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[3]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[3]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[2]/PPhosphatase2A/diff /kinetics/chain/kinetics[3]/PPhosphatase2A REAC B A addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/diff /kinetics/chain/kinetics[3]/PPhosphatase2A REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1* /kinetics/chain/kinetics[3]/PPhosphatase2A/craf-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A /kinetics/chain/kinetics[3]/PPhosphatase2A/craf-deph ENZYME n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK* /kinetics/chain/kinetics[3]/PPhosphatase2A/MAPKK-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A /kinetics/chain/kinetics[3]/PPhosphatase2A/MAPKK-deph ENZYME n addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser /kinetics/chain/kinetics[3]/PPhosphatase2A/MAPKK-deph-ser SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A /kinetics/chain/kinetics[3]/PPhosphatase2A/MAPKK-deph-ser ENZYME n addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1** /kinetics/chain/kinetics[3]/PPhosphatase2A/craf**-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A /kinetics/chain/kinetics[3]/PPhosphatase2A/craf**-deph ENZYME n addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A /kinetics/chain/kinetics[3]/PPhosphatase2A/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A /kinetics/chain/kinetics[3]/PPhosphatase2A/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ras/inact-GEF /kinetics/chain/kinetics[3]/Ras/dephosph-GEF PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ras/GEF* /kinetics/chain/kinetics[3]/Ras/dephosph-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[3]/Ras/inact-GEF REAC sA B addmsg /kinetics/chain/kinetics[3]/Ras/dephosph-GEF /kinetics/chain/kinetics[3]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[3]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[3]/Ras/inact-GEF REAC eA B addmsg /kinetics/chain/kinetics[3]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[3]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[2]/Ras/inact-GEF/diff /kinetics/chain/kinetics[3]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[3]/Ras/inact-GEF/diff /kinetics/chain/kinetics[3]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[3]/Ras/inact-GEF /kinetics/chain/kinetics[3]/Ras/inact-GEF/basal_GEF_activity ENZYME n addmsg /kinetics/chain/kinetics[3]/Ras/GDP-Ras /kinetics/chain/kinetics[3]/Ras/inact-GEF/basal_GEF_activity SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/inact-GEF /kinetics/chain/kinetics[3]/Ras/inact-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/inact-GEF /kinetics/chain/kinetics[3]/Ras/inact-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[3]/Ras/GEF* MM_PRD pA addmsg /kinetics/chain/kinetics[3]/Ras/dephosph-GEF /kinetics/chain/kinetics[3]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[3]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[3]/Ras/GEF* REAC eA B addmsg /kinetics/chain/kinetics[2]/Ras/GEF*/diff /kinetics/chain/kinetics[3]/Ras/GEF* REAC B A addmsg /kinetics/chain/kinetics[3]/Ras/GEF*/diff /kinetics/chain/kinetics[3]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[3]/Ras/GEF* /kinetics/chain/kinetics[3]/Ras/GEF*/GEF*-act-ras ENZYME n addmsg /kinetics/chain/kinetics[3]/Ras/GDP-Ras /kinetics/chain/kinetics[3]/Ras/GEF*/GEF*-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/GEF* /kinetics/chain/kinetics[3]/Ras/GEF*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/GEF* /kinetics/chain/kinetics[3]/Ras/GEF*/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ras-act-craf /kinetics/chain/kinetics[3]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[3]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[3]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[3]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[3]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[3]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[3]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[3]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[3]/Ras/GTP-Ras REAC sA B addmsg /kinetics/chain/kinetics[3]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[3]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[3]/Ras-act-unphosph-raf /kinetics/chain/kinetics[3]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[2]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[3]/Ras/GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[3]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[3]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[3]/Ras/GTP-Ras /kinetics/chain/kinetics[3]/Ras/GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/GTP-Ras /kinetics/chain/kinetics[3]/Ras/GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[3]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[3]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[3]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[3]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[3]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[3]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[3]/Ras/GDP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[3]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[3]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[2]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[3]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[3]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[3]/Ras/GDP-Ras REAC A B addmsg /kinetics/chain/kinetics[3]/Ras/GDP-Ras /kinetics/chain/kinetics[3]/Ras/GDP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/GDP-Ras /kinetics/chain/kinetics[3]/Ras/GDP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ras/GTP-Ras /kinetics/chain/kinetics[3]/Ras/Ras-intrinsic-GTPase SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/GDP-Ras /kinetics/chain/kinetics[3]/Ras/Ras-intrinsic-GTPase PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ras/GAP* /kinetics/chain/kinetics[3]/Ras/dephosph-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/GAP /kinetics/chain/kinetics[3]/Ras/dephosph-GAP PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[3]/Ras/GAP* MM_PRD pA addmsg /kinetics/chain/kinetics[3]/Ras/dephosph-GAP /kinetics/chain/kinetics[3]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[2]/Ras/GAP*/diff /kinetics/chain/kinetics[3]/Ras/GAP* REAC B A addmsg /kinetics/chain/kinetics[3]/Ras/GAP*/diff /kinetics/chain/kinetics[3]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[3]/Ras/GAP* /kinetics/chain/kinetics[3]/Ras/GAP*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/GAP* /kinetics/chain/kinetics[3]/Ras/GAP*/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[3]/Ras/GAP REAC sA B addmsg /kinetics/chain/kinetics[3]/Ras/dephosph-GAP /kinetics/chain/kinetics[3]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[3]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[3]/Ras/GAP REAC eA B addmsg /kinetics/chain/kinetics[2]/Ras/GAP/diff /kinetics/chain/kinetics[3]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[3]/Ras/GAP/diff /kinetics/chain/kinetics[3]/Ras/GAP REAC A B addmsg /kinetics/chain/kinetics[3]/Ras/GTP-Ras /kinetics/chain/kinetics[3]/Ras/GAP/GAP-inact-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/GAP /kinetics/chain/kinetics[3]/Ras/GAP/GAP-inact-ras ENZYME n addmsg /kinetics/chain/kinetics[3]/Ras/GAP /kinetics/chain/kinetics[3]/Ras/GAP/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/GAP /kinetics/chain/kinetics[3]/Ras/GAP/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ras/inact-GEF /kinetics/chain/kinetics[3]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/CaM-GEF /kinetics/chain/kinetics[3]/Ras/CaM-bind-GEF PRODUCT n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca4 /kinetics/chain/kinetics[3]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[3]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[3]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[3]/Ras/CaM-GEF REAC eA B addmsg /kinetics/chain/kinetics[2]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[3]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[3]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[3]/Ras/CaM-GEF REAC A B addmsg /kinetics/chain/kinetics[3]/Ras/GDP-Ras /kinetics/chain/kinetics[3]/Ras/CaM-GEF/CaM-GEF-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ras/CaM-GEF /kinetics/chain/kinetics[3]/Ras/CaM-GEF/CaM-GEF-act-ras ENZYME n addmsg /kinetics/chain/kinetics[3]/Ras/CaM-GEF /kinetics/chain/kinetics[3]/Ras/CaM-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/CaM-GEF /kinetics/chain/kinetics[3]/Ras/CaM-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[3]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM/diff /kinetics/chain/kinetics[3]/CaM/CaM REAC B A addmsg /kinetics/chain/kinetics[3]/CaM/CaM/diff /kinetics/chain/kinetics[3]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM /kinetics/chain/kinetics[3]/CaM/CaM/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/CaM/CaM /kinetics/chain/kinetics[3]/CaM/CaM/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca3 /kinetics/chain/kinetics[3]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca4 /kinetics/chain/kinetics[3]/CaM/CaM-Ca3-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ca /kinetics/chain/kinetics[3]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[3]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[3]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[3]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[3]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca3 /kinetics/chain/kinetics[3]/CaM/CaM-Ca3/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca3 /kinetics/chain/kinetics[3]/CaM/CaM-Ca3/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[3]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[3]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[3]/PKM/trigger_PKM /kinetics/chain/kinetics[3]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[3]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[3]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca4 /kinetics/chain/kinetics[3]/CaM/CaM-Ca4/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca4 /kinetics/chain/kinetics[3]/CaM/CaM-Ca4/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/CaM/CaM /kinetics/chain/kinetics[3]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca /kinetics/chain/kinetics[3]/CaM/CaM-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ca /kinetics/chain/kinetics[3]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[3]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[3]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[3]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[3]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca2 /kinetics/chain/kinetics[3]/CaM/CaM-Ca2/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca2 /kinetics/chain/kinetics[3]/CaM/CaM-Ca2/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca3 /kinetics/chain/kinetics[3]/CaM/CaM-Ca2-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca2 /kinetics/chain/kinetics[3]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ca /kinetics/chain/kinetics[3]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca2 /kinetics/chain/kinetics[3]/CaM/CaM-Ca-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca /kinetics/chain/kinetics[3]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/Ca /kinetics/chain/kinetics[3]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[3]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[3]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[2]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[3]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[3]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca /kinetics/chain/kinetics[3]/CaM/CaM-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca /kinetics/chain/kinetics[3]/CaM/CaM-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[3]/Ca REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[3]/Ca REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[3]/Ca REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[3]/Ca REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[3]/Ca REAC A B addmsg /kinetics/chain/kinetics[3]/Ca_diff /kinetics/chain/kinetics[3]/Ca REAC B A addmsg /kinetics/chain/kinetics[2]/Ca/diff /kinetics/chain/kinetics[3]/Ca REAC B A addmsg /kinetics/chain/kinetics[3]/Ca/diff /kinetics/chain/kinetics[3]/Ca REAC A B addmsg /kinetics/chain/kinetics[3]/Ca /kinetics/chain/kinetics[3]/Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ca /kinetics/chain/kinetics[3]/Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1 /kinetics/chain/kinetics[3]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[3]/Ras-act-unphosph-raf PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ras/GTP-Ras /kinetics/chain/kinetics[3]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKM/trigger_PKM /kinetics/chain/kinetics[3]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[2]/PKM/Ca_detector/diff /kinetics/chain/kinetics[3]/PKM/Ca_detector REAC B A addmsg /kinetics/chain/kinetics[3]/PKM/Ca_detector/diff /kinetics/chain/kinetics[3]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[3]/PKM/Ca_detector /kinetics/chain/kinetics[3]/PKM/Ca_detector/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKM/Ca_detector /kinetics/chain/kinetics[3]/PKM/Ca_detector/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[3]/PKM/PKM_synthesis REAC eA B addmsg /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[3]/PKM/PKM_synthesis MM_PRD pA addmsg /kinetics/chain/kinetics[3]/PKM/turn_off_activator /kinetics/chain/kinetics[3]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[2]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[3]/PKM/PKM_synthesis REAC B A addmsg /kinetics/chain/kinetics[3]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[3]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[3]/PKM/PKM_synthesis /kinetics/chain/kinetics[3]/PKM/PKM_synthesis/kenz ENZYME n addmsg /kinetics/chain/kinetics[3]/PKM/AA_pool /kinetics/chain/kinetics[3]/PKM/PKM_synthesis/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKM/PKM_synthesis /kinetics/chain/kinetics[3]/PKM/PKM_synthesis/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKM/PKM_synthesis /kinetics/chain/kinetics[3]/PKM/PKM_synthesis/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[3]/PKM/AA_pool REAC sA B addmsg /kinetics/chain/kinetics[3]/PKC/PKM-zeta /kinetics/chain/kinetics[3]/PKM/PKM_degradation SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKM/degraded_PKM /kinetics/chain/kinetics[3]/PKM/PKM_degradation PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKM/PKM_degradation /kinetics/chain/kinetics[3]/PKM/degraded_PKM REAC B A addmsg /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex REAC eA B addmsg /kinetics/chain/kinetics[3]/PKM/trigger_PKM /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[2]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex REAC A B addmsg /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex/kenz ENZYME n addmsg /kinetics/chain/kinetics[3]/PKM/PKM_activator /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[3]/PKM/PKM_activator REAC sA B addmsg /kinetics/chain/kinetics[3]/PKM/turn_off_activator /kinetics/chain/kinetics[3]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[2]/PKM/PKM_activator/diff /kinetics/chain/kinetics[3]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[3]/PKM/PKM_activator/diff /kinetics/chain/kinetics[3]/PKM/PKM_activator REAC A B addmsg /kinetics/chain/kinetics[3]/PKM/PKM_activator /kinetics/chain/kinetics[3]/PKM/PKM_activator/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKM/PKM_activator /kinetics/chain/kinetics[3]/PKM/PKM_activator/diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/PKM/PKM_synthesis /kinetics/chain/kinetics[3]/PKM/turn_off_activator SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKM/PKM_activator /kinetics/chain/kinetics[3]/PKM/turn_off_activator PRODUCT n addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca4 /kinetics/chain/kinetics[3]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKM/Ca_detector /kinetics/chain/kinetics[3]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex /kinetics/chain/kinetics[3]/PKM/trigger_PKM PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ca_diff /kinetics/chain/kinetics[3]/Ca_input REAC A B addmsg /kinetics/chain/kinetics[3]/Ca /kinetics/chain/kinetics[3]/Ca_diff PRODUCT n addmsg /kinetics/chain/kinetics[3]/Ca_input /kinetics/chain/kinetics[3]/Ca_diff SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[4]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[4]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[4]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[4]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[4]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[4]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca /kinetics/chain/kinetics[4]/PKC/PKC-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca /kinetics/chain/kinetics[4]/PKC/PKC-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca /kinetics/chain/kinetics[4]/PKC/PKC-act-by-Ca PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic /kinetics/chain/kinetics[4]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ca /kinetics/chain/kinetics[4]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca /kinetics/chain/kinetics[4]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[4]/PKC/PKC-act-by-DAG PRODUCT n addmsg /kinetics/chain/kinetics[4]/DAG /kinetics/chain/kinetics[4]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca /kinetics/chain/kinetics[4]/PKC/PKC-Ca-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[4]/PKC/PKC-Ca-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[4]/PKC/PKC-DAG-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[4]/PKC/PKC-DAG-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[4]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[4]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[4]/PKC/PKC-Ca-memb* REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[4]/PKC/PKC-Ca-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[4]/PKC/PKC-Ca-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[4]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[3]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[4]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[4]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[4]/PKC/PKC-DAG-memb* REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[4]/PKC/PKC-DAG-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[4]/PKC/PKC-DAG-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[4]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-DAG /kinetics/chain/kinetics[4]/PKC/PKC-n-DAG PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic /kinetics/chain/kinetics[4]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/DAG /kinetics/chain/kinetics[4]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-n-DAG /kinetics/chain/kinetics[4]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[3]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[4]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[4]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[4]/PKC/PKC-DAG REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKC-DAG /kinetics/chain/kinetics[4]/PKC/PKC-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-DAG /kinetics/chain/kinetics[4]/PKC/PKC-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKC-n-DAG /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic REAC B A addmsg /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[4]/PKC/PKM-zeta MM_PRD pA addmsg /kinetics/chain/kinetics[4]/PKM/PKM_degradation /kinetics/chain/kinetics[4]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[3]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[4]/PKC/PKM-zeta REAC B A addmsg /kinetics/chain/kinetics[4]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[4]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKM-zeta /kinetics/chain/kinetics[4]/PKC/PKM-zeta/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKM-zeta /kinetics/chain/kinetics[4]/PKC/PKM-zeta/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[4]/DAG REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKC-n-DAG /kinetics/chain/kinetics[4]/DAG REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[4]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[4]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[4]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[4]/PKC/PKM-zeta /kinetics/chain/kinetics[4]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[4]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[4]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[4]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[4]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[4]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[4]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[4]/PKC-active /kinetics/chain/kinetics[4]/PKC-active/PKC-act-raf ENZYME n addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1 /kinetics/chain/kinetics[4]/PKC-active/PKC-act-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC-active /kinetics/chain/kinetics[4]/PKC-active/PKC-inact-GAP ENZYME n addmsg /kinetics/chain/kinetics[4]/Ras/GAP /kinetics/chain/kinetics[4]/PKC-active/PKC-inact-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC-active /kinetics/chain/kinetics[4]/PKC-active/PKC-act-GEF ENZYME n addmsg /kinetics/chain/kinetics[4]/Ras/inact-GEF /kinetics/chain/kinetics[4]/PKC-active/PKC-act-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[4]/MAPK* REAC eA B addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[4]/MAPK* MM_PRD pA addmsg /kinetics/chain/kinetics[4]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[4]/MAPK* REAC sA B addmsg /kinetics/chain/kinetics[3]/MAPK*/diff /kinetics/chain/kinetics[4]/MAPK* REAC B A addmsg /kinetics/chain/kinetics[4]/MAPK*/diff /kinetics/chain/kinetics[4]/MAPK* REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK* /kinetics/chain/kinetics[4]/MAPK*/MAPK*-feedback ENZYME n addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1* /kinetics/chain/kinetics[4]/MAPK*/MAPK*-feedback SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK* /kinetics/chain/kinetics[4]/MAPK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK* /kinetics/chain/kinetics[4]/MAPK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[4]/MAPK/craf-1 REAC sA B addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[4]/MAPK/craf-1 MM_PRD pA addmsg /kinetics/chain/kinetics[4]/Ras-act-unphosph-raf /kinetics/chain/kinetics[4]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1/diff /kinetics/chain/kinetics[4]/MAPK/craf-1 REAC B A addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1/diff /kinetics/chain/kinetics[4]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1 /kinetics/chain/kinetics[4]/MAPK/craf-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1 /kinetics/chain/kinetics[4]/MAPK/craf-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[4]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[4]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[4]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[4]/Ras-act-craf /kinetics/chain/kinetics[4]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[4]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[4]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1*/diff /kinetics/chain/kinetics[4]/MAPK/craf-1* REAC B A addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1*/diff /kinetics/chain/kinetics[4]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1* /kinetics/chain/kinetics[4]/MAPK/craf-1*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1* /kinetics/chain/kinetics[4]/MAPK/craf-1*/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[4]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[4]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[4]/MAPK/MAPKK MM_PRD pA addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK/diff /kinetics/chain/kinetics[4]/MAPK/MAPKK REAC B A addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK/diff /kinetics/chain/kinetics[4]/MAPK/MAPKK REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK /kinetics/chain/kinetics[4]/MAPK/MAPKK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK /kinetics/chain/kinetics[4]/MAPK/MAPKK/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[4]/MAPK/MAPK REAC sA B addmsg /kinetics/chain/kinetics[4]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[4]/MAPK/MAPK MM_PRD pA addmsg /kinetics/chain/kinetics[3]/MAPK/MAPK/diff /kinetics/chain/kinetics[4]/MAPK/MAPK REAC B A addmsg /kinetics/chain/kinetics[4]/MAPK/MAPK/diff /kinetics/chain/kinetics[4]/MAPK/MAPK REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK/MAPK /kinetics/chain/kinetics[4]/MAPK/MAPK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPK /kinetics/chain/kinetics[4]/MAPK/MAPK/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[4]/MAPK/craf-1** MM_PRD pA addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[4]/MAPK/craf-1** REAC sA B addmsg /kinetics/chain/kinetics[3]/MAPK/craf-1**/diff /kinetics/chain/kinetics[4]/MAPK/craf-1** REAC B A addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1**/diff /kinetics/chain/kinetics[4]/MAPK/craf-1** REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1** /kinetics/chain/kinetics[4]/MAPK/craf-1**/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1** /kinetics/chain/kinetics[4]/MAPK/craf-1**/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[4]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[4]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[3]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr REAC B A addmsg /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[4]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[4]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[4]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[4]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[4]/MAPK/MAPKK* REAC sA B addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[4]/MAPK/MAPKK* REAC B A addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[4]/MAPK/MAPKK* REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK/MAPK /kinetics/chain/kinetics[4]/MAPK/MAPKK*/MAPKKtyr SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK* /kinetics/chain/kinetics[4]/MAPK/MAPKK*/MAPKKtyr ENZYME n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr /kinetics/chain/kinetics[4]/MAPK/MAPKK*/MAPKKthr SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK* /kinetics/chain/kinetics[4]/MAPK/MAPKK*/MAPKKthr ENZYME n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK* /kinetics/chain/kinetics[4]/MAPK/MAPKK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK* /kinetics/chain/kinetics[4]/MAPK/MAPKK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[3]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser REAC B A addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[4]/Ras-act-unphosph-raf /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[3]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[4]/Ras-act-craf /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[3]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[4]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[4]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[4]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[3]/MKP-1/diff /kinetics/chain/kinetics[4]/MKP-1 REAC B A addmsg /kinetics/chain/kinetics[4]/MKP-1/diff /kinetics/chain/kinetics[4]/MKP-1 REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr /kinetics/chain/kinetics[4]/MKP-1/MKP1-tyr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MKP-1 /kinetics/chain/kinetics[4]/MKP-1/MKP1-tyr-deph ENZYME n addmsg /kinetics/chain/kinetics[4]/MAPK* /kinetics/chain/kinetics[4]/MKP-1/MKP1-thr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MKP-1 /kinetics/chain/kinetics[4]/MKP-1/MKP1-thr-deph ENZYME n addmsg /kinetics/chain/kinetics[4]/MKP-1 /kinetics/chain/kinetics[4]/MKP-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MKP-1 /kinetics/chain/kinetics[4]/MKP-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1* /kinetics/chain/kinetics[4]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[4]/Ras-act-craf PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ras/GTP-Ras /kinetics/chain/kinetics[4]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[4]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[4]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[4]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[4]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[3]/PPhosphatase2A/diff /kinetics/chain/kinetics[4]/PPhosphatase2A REAC B A addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/diff /kinetics/chain/kinetics[4]/PPhosphatase2A REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1* /kinetics/chain/kinetics[4]/PPhosphatase2A/craf-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A /kinetics/chain/kinetics[4]/PPhosphatase2A/craf-deph ENZYME n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK* /kinetics/chain/kinetics[4]/PPhosphatase2A/MAPKK-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A /kinetics/chain/kinetics[4]/PPhosphatase2A/MAPKK-deph ENZYME n addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser /kinetics/chain/kinetics[4]/PPhosphatase2A/MAPKK-deph-ser SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A /kinetics/chain/kinetics[4]/PPhosphatase2A/MAPKK-deph-ser ENZYME n addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1** /kinetics/chain/kinetics[4]/PPhosphatase2A/craf**-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A /kinetics/chain/kinetics[4]/PPhosphatase2A/craf**-deph ENZYME n addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A /kinetics/chain/kinetics[4]/PPhosphatase2A/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A /kinetics/chain/kinetics[4]/PPhosphatase2A/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ras/inact-GEF /kinetics/chain/kinetics[4]/Ras/dephosph-GEF PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ras/GEF* /kinetics/chain/kinetics[4]/Ras/dephosph-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[4]/Ras/inact-GEF REAC sA B addmsg /kinetics/chain/kinetics[4]/Ras/dephosph-GEF /kinetics/chain/kinetics[4]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[4]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[4]/Ras/inact-GEF REAC eA B addmsg /kinetics/chain/kinetics[4]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[4]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[3]/Ras/inact-GEF/diff /kinetics/chain/kinetics[4]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[4]/Ras/inact-GEF/diff /kinetics/chain/kinetics[4]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[4]/Ras/inact-GEF /kinetics/chain/kinetics[4]/Ras/inact-GEF/basal_GEF_activity ENZYME n addmsg /kinetics/chain/kinetics[4]/Ras/GDP-Ras /kinetics/chain/kinetics[4]/Ras/inact-GEF/basal_GEF_activity SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/inact-GEF /kinetics/chain/kinetics[4]/Ras/inact-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/inact-GEF /kinetics/chain/kinetics[4]/Ras/inact-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[4]/Ras/GEF* MM_PRD pA addmsg /kinetics/chain/kinetics[4]/Ras/dephosph-GEF /kinetics/chain/kinetics[4]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[4]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[4]/Ras/GEF* REAC eA B addmsg /kinetics/chain/kinetics[3]/Ras/GEF*/diff /kinetics/chain/kinetics[4]/Ras/GEF* REAC B A addmsg /kinetics/chain/kinetics[4]/Ras/GEF*/diff /kinetics/chain/kinetics[4]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[4]/Ras/GEF* /kinetics/chain/kinetics[4]/Ras/GEF*/GEF*-act-ras ENZYME n addmsg /kinetics/chain/kinetics[4]/Ras/GDP-Ras /kinetics/chain/kinetics[4]/Ras/GEF*/GEF*-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/GEF* /kinetics/chain/kinetics[4]/Ras/GEF*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/GEF* /kinetics/chain/kinetics[4]/Ras/GEF*/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ras-act-craf /kinetics/chain/kinetics[4]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[4]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[4]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[4]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[4]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[4]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[4]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[4]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[4]/Ras/GTP-Ras REAC sA B addmsg /kinetics/chain/kinetics[4]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[4]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[4]/Ras-act-unphosph-raf /kinetics/chain/kinetics[4]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[3]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[4]/Ras/GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[4]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[4]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[4]/Ras/GTP-Ras /kinetics/chain/kinetics[4]/Ras/GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/GTP-Ras /kinetics/chain/kinetics[4]/Ras/GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[4]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[4]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[4]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[4]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[4]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[4]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[4]/Ras/GDP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[4]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[4]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[3]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[4]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[4]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[4]/Ras/GDP-Ras REAC A B addmsg /kinetics/chain/kinetics[4]/Ras/GDP-Ras /kinetics/chain/kinetics[4]/Ras/GDP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/GDP-Ras /kinetics/chain/kinetics[4]/Ras/GDP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ras/GTP-Ras /kinetics/chain/kinetics[4]/Ras/Ras-intrinsic-GTPase SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/GDP-Ras /kinetics/chain/kinetics[4]/Ras/Ras-intrinsic-GTPase PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ras/GAP* /kinetics/chain/kinetics[4]/Ras/dephosph-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/GAP /kinetics/chain/kinetics[4]/Ras/dephosph-GAP PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[4]/Ras/GAP* MM_PRD pA addmsg /kinetics/chain/kinetics[4]/Ras/dephosph-GAP /kinetics/chain/kinetics[4]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[3]/Ras/GAP*/diff /kinetics/chain/kinetics[4]/Ras/GAP* REAC B A addmsg /kinetics/chain/kinetics[4]/Ras/GAP*/diff /kinetics/chain/kinetics[4]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[4]/Ras/GAP* /kinetics/chain/kinetics[4]/Ras/GAP*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/GAP* /kinetics/chain/kinetics[4]/Ras/GAP*/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[4]/Ras/GAP REAC sA B addmsg /kinetics/chain/kinetics[4]/Ras/dephosph-GAP /kinetics/chain/kinetics[4]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[4]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[4]/Ras/GAP REAC eA B addmsg /kinetics/chain/kinetics[3]/Ras/GAP/diff /kinetics/chain/kinetics[4]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[4]/Ras/GAP/diff /kinetics/chain/kinetics[4]/Ras/GAP REAC A B addmsg /kinetics/chain/kinetics[4]/Ras/GTP-Ras /kinetics/chain/kinetics[4]/Ras/GAP/GAP-inact-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/GAP /kinetics/chain/kinetics[4]/Ras/GAP/GAP-inact-ras ENZYME n addmsg /kinetics/chain/kinetics[4]/Ras/GAP /kinetics/chain/kinetics[4]/Ras/GAP/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/GAP /kinetics/chain/kinetics[4]/Ras/GAP/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ras/inact-GEF /kinetics/chain/kinetics[4]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/CaM-GEF /kinetics/chain/kinetics[4]/Ras/CaM-bind-GEF PRODUCT n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca4 /kinetics/chain/kinetics[4]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[4]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[4]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[4]/Ras/CaM-GEF REAC eA B addmsg /kinetics/chain/kinetics[3]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[4]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[4]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[4]/Ras/CaM-GEF REAC A B addmsg /kinetics/chain/kinetics[4]/Ras/GDP-Ras /kinetics/chain/kinetics[4]/Ras/CaM-GEF/CaM-GEF-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ras/CaM-GEF /kinetics/chain/kinetics[4]/Ras/CaM-GEF/CaM-GEF-act-ras ENZYME n addmsg /kinetics/chain/kinetics[4]/Ras/CaM-GEF /kinetics/chain/kinetics[4]/Ras/CaM-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/CaM-GEF /kinetics/chain/kinetics[4]/Ras/CaM-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[4]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM/diff /kinetics/chain/kinetics[4]/CaM/CaM REAC B A addmsg /kinetics/chain/kinetics[4]/CaM/CaM/diff /kinetics/chain/kinetics[4]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM /kinetics/chain/kinetics[4]/CaM/CaM/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/CaM/CaM /kinetics/chain/kinetics[4]/CaM/CaM/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca3 /kinetics/chain/kinetics[4]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca4 /kinetics/chain/kinetics[4]/CaM/CaM-Ca3-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ca /kinetics/chain/kinetics[4]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[4]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[4]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[4]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[4]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca3 /kinetics/chain/kinetics[4]/CaM/CaM-Ca3/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca3 /kinetics/chain/kinetics[4]/CaM/CaM-Ca3/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[4]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[4]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[4]/PKM/trigger_PKM /kinetics/chain/kinetics[4]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[4]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[4]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca4 /kinetics/chain/kinetics[4]/CaM/CaM-Ca4/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca4 /kinetics/chain/kinetics[4]/CaM/CaM-Ca4/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/CaM/CaM /kinetics/chain/kinetics[4]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca /kinetics/chain/kinetics[4]/CaM/CaM-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ca /kinetics/chain/kinetics[4]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[4]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[4]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[4]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[4]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca2 /kinetics/chain/kinetics[4]/CaM/CaM-Ca2/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca2 /kinetics/chain/kinetics[4]/CaM/CaM-Ca2/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca3 /kinetics/chain/kinetics[4]/CaM/CaM-Ca2-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca2 /kinetics/chain/kinetics[4]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ca /kinetics/chain/kinetics[4]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca2 /kinetics/chain/kinetics[4]/CaM/CaM-Ca-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca /kinetics/chain/kinetics[4]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/Ca /kinetics/chain/kinetics[4]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[4]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[4]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[3]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[4]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[4]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca /kinetics/chain/kinetics[4]/CaM/CaM-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca /kinetics/chain/kinetics[4]/CaM/CaM-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[4]/Ca REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[4]/Ca REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[4]/Ca REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[4]/Ca REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[4]/Ca REAC A B addmsg /kinetics/chain/kinetics[4]/Ca_diff /kinetics/chain/kinetics[4]/Ca REAC B A addmsg /kinetics/chain/kinetics[3]/Ca/diff /kinetics/chain/kinetics[4]/Ca REAC B A addmsg /kinetics/chain/kinetics[4]/Ca/diff /kinetics/chain/kinetics[4]/Ca REAC A B addmsg /kinetics/chain/kinetics[4]/Ca /kinetics/chain/kinetics[4]/Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ca /kinetics/chain/kinetics[4]/Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1 /kinetics/chain/kinetics[4]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[4]/Ras-act-unphosph-raf PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ras/GTP-Ras /kinetics/chain/kinetics[4]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKM/trigger_PKM /kinetics/chain/kinetics[4]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[3]/PKM/Ca_detector/diff /kinetics/chain/kinetics[4]/PKM/Ca_detector REAC B A addmsg /kinetics/chain/kinetics[4]/PKM/Ca_detector/diff /kinetics/chain/kinetics[4]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[4]/PKM/Ca_detector /kinetics/chain/kinetics[4]/PKM/Ca_detector/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKM/Ca_detector /kinetics/chain/kinetics[4]/PKM/Ca_detector/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[4]/PKM/PKM_synthesis REAC eA B addmsg /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[4]/PKM/PKM_synthesis MM_PRD pA addmsg /kinetics/chain/kinetics[4]/PKM/turn_off_activator /kinetics/chain/kinetics[4]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[3]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[4]/PKM/PKM_synthesis REAC B A addmsg /kinetics/chain/kinetics[4]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[4]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[4]/PKM/PKM_synthesis /kinetics/chain/kinetics[4]/PKM/PKM_synthesis/kenz ENZYME n addmsg /kinetics/chain/kinetics[4]/PKM/AA_pool /kinetics/chain/kinetics[4]/PKM/PKM_synthesis/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKM/PKM_synthesis /kinetics/chain/kinetics[4]/PKM/PKM_synthesis/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKM/PKM_synthesis /kinetics/chain/kinetics[4]/PKM/PKM_synthesis/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[4]/PKM/AA_pool REAC sA B addmsg /kinetics/chain/kinetics[4]/PKC/PKM-zeta /kinetics/chain/kinetics[4]/PKM/PKM_degradation SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKM/degraded_PKM /kinetics/chain/kinetics[4]/PKM/PKM_degradation PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKM/PKM_degradation /kinetics/chain/kinetics[4]/PKM/degraded_PKM REAC B A addmsg /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex REAC eA B addmsg /kinetics/chain/kinetics[4]/PKM/trigger_PKM /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[3]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex REAC A B addmsg /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex/kenz ENZYME n addmsg /kinetics/chain/kinetics[4]/PKM/PKM_activator /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[4]/PKM/PKM_activator REAC sA B addmsg /kinetics/chain/kinetics[4]/PKM/turn_off_activator /kinetics/chain/kinetics[4]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[3]/PKM/PKM_activator/diff /kinetics/chain/kinetics[4]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[4]/PKM/PKM_activator/diff /kinetics/chain/kinetics[4]/PKM/PKM_activator REAC A B addmsg /kinetics/chain/kinetics[4]/PKM/PKM_activator /kinetics/chain/kinetics[4]/PKM/PKM_activator/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKM/PKM_activator /kinetics/chain/kinetics[4]/PKM/PKM_activator/diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/PKM/PKM_synthesis /kinetics/chain/kinetics[4]/PKM/turn_off_activator SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKM/PKM_activator /kinetics/chain/kinetics[4]/PKM/turn_off_activator PRODUCT n addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca4 /kinetics/chain/kinetics[4]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKM/Ca_detector /kinetics/chain/kinetics[4]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex /kinetics/chain/kinetics[4]/PKM/trigger_PKM PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ca_diff /kinetics/chain/kinetics[4]/Ca_input REAC A B addmsg /kinetics/chain/kinetics[4]/Ca /kinetics/chain/kinetics[4]/Ca_diff PRODUCT n addmsg /kinetics/chain/kinetics[4]/Ca_input /kinetics/chain/kinetics[4]/Ca_diff SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[5]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[5]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[5]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[5]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[5]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[5]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca /kinetics/chain/kinetics[5]/PKC/PKC-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca /kinetics/chain/kinetics[5]/PKC/PKC-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca /kinetics/chain/kinetics[5]/PKC/PKC-act-by-Ca PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic /kinetics/chain/kinetics[5]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ca /kinetics/chain/kinetics[5]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca /kinetics/chain/kinetics[5]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[5]/PKC/PKC-act-by-DAG PRODUCT n addmsg /kinetics/chain/kinetics[5]/DAG /kinetics/chain/kinetics[5]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca /kinetics/chain/kinetics[5]/PKC/PKC-Ca-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[5]/PKC/PKC-Ca-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[5]/PKC/PKC-DAG-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[5]/PKC/PKC-DAG-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[5]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[5]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[5]/PKC/PKC-Ca-memb* REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[5]/PKC/PKC-Ca-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[5]/PKC/PKC-Ca-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[5]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[4]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[5]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[5]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[5]/PKC/PKC-DAG-memb* REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[5]/PKC/PKC-DAG-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[5]/PKC/PKC-DAG-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[5]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-DAG /kinetics/chain/kinetics[5]/PKC/PKC-n-DAG PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic /kinetics/chain/kinetics[5]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/DAG /kinetics/chain/kinetics[5]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-n-DAG /kinetics/chain/kinetics[5]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[4]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[5]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[5]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[5]/PKC/PKC-DAG REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKC-DAG /kinetics/chain/kinetics[5]/PKC/PKC-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-DAG /kinetics/chain/kinetics[5]/PKC/PKC-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKC-n-DAG /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic REAC B A addmsg /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[5]/PKC/PKM-zeta MM_PRD pA addmsg /kinetics/chain/kinetics[5]/PKM/PKM_degradation /kinetics/chain/kinetics[5]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[4]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[5]/PKC/PKM-zeta REAC B A addmsg /kinetics/chain/kinetics[5]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[5]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKM-zeta /kinetics/chain/kinetics[5]/PKC/PKM-zeta/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKM-zeta /kinetics/chain/kinetics[5]/PKC/PKM-zeta/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[5]/DAG REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKC-n-DAG /kinetics/chain/kinetics[5]/DAG REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[5]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[5]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[5]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[5]/PKC/PKM-zeta /kinetics/chain/kinetics[5]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[5]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[5]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[5]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[5]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[5]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[5]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[5]/PKC-active /kinetics/chain/kinetics[5]/PKC-active/PKC-act-raf ENZYME n addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1 /kinetics/chain/kinetics[5]/PKC-active/PKC-act-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC-active /kinetics/chain/kinetics[5]/PKC-active/PKC-inact-GAP ENZYME n addmsg /kinetics/chain/kinetics[5]/Ras/GAP /kinetics/chain/kinetics[5]/PKC-active/PKC-inact-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC-active /kinetics/chain/kinetics[5]/PKC-active/PKC-act-GEF ENZYME n addmsg /kinetics/chain/kinetics[5]/Ras/inact-GEF /kinetics/chain/kinetics[5]/PKC-active/PKC-act-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[5]/MAPK* REAC eA B addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[5]/MAPK* MM_PRD pA addmsg /kinetics/chain/kinetics[5]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[5]/MAPK* REAC sA B addmsg /kinetics/chain/kinetics[4]/MAPK*/diff /kinetics/chain/kinetics[5]/MAPK* REAC B A addmsg /kinetics/chain/kinetics[5]/MAPK*/diff /kinetics/chain/kinetics[5]/MAPK* REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK* /kinetics/chain/kinetics[5]/MAPK*/MAPK*-feedback ENZYME n addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1* /kinetics/chain/kinetics[5]/MAPK*/MAPK*-feedback SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK* /kinetics/chain/kinetics[5]/MAPK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK* /kinetics/chain/kinetics[5]/MAPK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[5]/MAPK/craf-1 REAC sA B addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[5]/MAPK/craf-1 MM_PRD pA addmsg /kinetics/chain/kinetics[5]/Ras-act-unphosph-raf /kinetics/chain/kinetics[5]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1/diff /kinetics/chain/kinetics[5]/MAPK/craf-1 REAC B A addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1/diff /kinetics/chain/kinetics[5]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1 /kinetics/chain/kinetics[5]/MAPK/craf-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1 /kinetics/chain/kinetics[5]/MAPK/craf-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[5]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[5]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[5]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[5]/Ras-act-craf /kinetics/chain/kinetics[5]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[5]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[5]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1*/diff /kinetics/chain/kinetics[5]/MAPK/craf-1* REAC B A addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1*/diff /kinetics/chain/kinetics[5]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1* /kinetics/chain/kinetics[5]/MAPK/craf-1*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1* /kinetics/chain/kinetics[5]/MAPK/craf-1*/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[5]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[5]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[5]/MAPK/MAPKK MM_PRD pA addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK/diff /kinetics/chain/kinetics[5]/MAPK/MAPKK REAC B A addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK/diff /kinetics/chain/kinetics[5]/MAPK/MAPKK REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK /kinetics/chain/kinetics[5]/MAPK/MAPKK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK /kinetics/chain/kinetics[5]/MAPK/MAPKK/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[5]/MAPK/MAPK REAC sA B addmsg /kinetics/chain/kinetics[5]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[5]/MAPK/MAPK MM_PRD pA addmsg /kinetics/chain/kinetics[4]/MAPK/MAPK/diff /kinetics/chain/kinetics[5]/MAPK/MAPK REAC B A addmsg /kinetics/chain/kinetics[5]/MAPK/MAPK/diff /kinetics/chain/kinetics[5]/MAPK/MAPK REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK/MAPK /kinetics/chain/kinetics[5]/MAPK/MAPK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPK /kinetics/chain/kinetics[5]/MAPK/MAPK/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[5]/MAPK/craf-1** MM_PRD pA addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[5]/MAPK/craf-1** REAC sA B addmsg /kinetics/chain/kinetics[4]/MAPK/craf-1**/diff /kinetics/chain/kinetics[5]/MAPK/craf-1** REAC B A addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1**/diff /kinetics/chain/kinetics[5]/MAPK/craf-1** REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1** /kinetics/chain/kinetics[5]/MAPK/craf-1**/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1** /kinetics/chain/kinetics[5]/MAPK/craf-1**/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[5]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[5]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[4]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr REAC B A addmsg /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[5]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[5]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[5]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[5]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[5]/MAPK/MAPKK* REAC sA B addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[5]/MAPK/MAPKK* REAC B A addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[5]/MAPK/MAPKK* REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK/MAPK /kinetics/chain/kinetics[5]/MAPK/MAPKK*/MAPKKtyr SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK* /kinetics/chain/kinetics[5]/MAPK/MAPKK*/MAPKKtyr ENZYME n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr /kinetics/chain/kinetics[5]/MAPK/MAPKK*/MAPKKthr SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK* /kinetics/chain/kinetics[5]/MAPK/MAPKK*/MAPKKthr ENZYME n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK* /kinetics/chain/kinetics[5]/MAPK/MAPKK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK* /kinetics/chain/kinetics[5]/MAPK/MAPKK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[4]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser REAC B A addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[5]/Ras-act-unphosph-raf /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[4]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[5]/Ras-act-craf /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[4]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[5]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[5]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[5]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[4]/MKP-1/diff /kinetics/chain/kinetics[5]/MKP-1 REAC B A addmsg /kinetics/chain/kinetics[5]/MKP-1/diff /kinetics/chain/kinetics[5]/MKP-1 REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr /kinetics/chain/kinetics[5]/MKP-1/MKP1-tyr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MKP-1 /kinetics/chain/kinetics[5]/MKP-1/MKP1-tyr-deph ENZYME n addmsg /kinetics/chain/kinetics[5]/MAPK* /kinetics/chain/kinetics[5]/MKP-1/MKP1-thr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MKP-1 /kinetics/chain/kinetics[5]/MKP-1/MKP1-thr-deph ENZYME n addmsg /kinetics/chain/kinetics[5]/MKP-1 /kinetics/chain/kinetics[5]/MKP-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MKP-1 /kinetics/chain/kinetics[5]/MKP-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1* /kinetics/chain/kinetics[5]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[5]/Ras-act-craf PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ras/GTP-Ras /kinetics/chain/kinetics[5]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[5]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[5]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[5]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[5]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[4]/PPhosphatase2A/diff /kinetics/chain/kinetics[5]/PPhosphatase2A REAC B A addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/diff /kinetics/chain/kinetics[5]/PPhosphatase2A REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1* /kinetics/chain/kinetics[5]/PPhosphatase2A/craf-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A /kinetics/chain/kinetics[5]/PPhosphatase2A/craf-deph ENZYME n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK* /kinetics/chain/kinetics[5]/PPhosphatase2A/MAPKK-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A /kinetics/chain/kinetics[5]/PPhosphatase2A/MAPKK-deph ENZYME n addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser /kinetics/chain/kinetics[5]/PPhosphatase2A/MAPKK-deph-ser SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A /kinetics/chain/kinetics[5]/PPhosphatase2A/MAPKK-deph-ser ENZYME n addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1** /kinetics/chain/kinetics[5]/PPhosphatase2A/craf**-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A /kinetics/chain/kinetics[5]/PPhosphatase2A/craf**-deph ENZYME n addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A /kinetics/chain/kinetics[5]/PPhosphatase2A/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A /kinetics/chain/kinetics[5]/PPhosphatase2A/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ras/inact-GEF /kinetics/chain/kinetics[5]/Ras/dephosph-GEF PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ras/GEF* /kinetics/chain/kinetics[5]/Ras/dephosph-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[5]/Ras/inact-GEF REAC sA B addmsg /kinetics/chain/kinetics[5]/Ras/dephosph-GEF /kinetics/chain/kinetics[5]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[5]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[5]/Ras/inact-GEF REAC eA B addmsg /kinetics/chain/kinetics[5]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[5]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[4]/Ras/inact-GEF/diff /kinetics/chain/kinetics[5]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[5]/Ras/inact-GEF/diff /kinetics/chain/kinetics[5]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[5]/Ras/inact-GEF /kinetics/chain/kinetics[5]/Ras/inact-GEF/basal_GEF_activity ENZYME n addmsg /kinetics/chain/kinetics[5]/Ras/GDP-Ras /kinetics/chain/kinetics[5]/Ras/inact-GEF/basal_GEF_activity SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/inact-GEF /kinetics/chain/kinetics[5]/Ras/inact-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/inact-GEF /kinetics/chain/kinetics[5]/Ras/inact-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[5]/Ras/GEF* MM_PRD pA addmsg /kinetics/chain/kinetics[5]/Ras/dephosph-GEF /kinetics/chain/kinetics[5]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[5]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[5]/Ras/GEF* REAC eA B addmsg /kinetics/chain/kinetics[4]/Ras/GEF*/diff /kinetics/chain/kinetics[5]/Ras/GEF* REAC B A addmsg /kinetics/chain/kinetics[5]/Ras/GEF*/diff /kinetics/chain/kinetics[5]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[5]/Ras/GEF* /kinetics/chain/kinetics[5]/Ras/GEF*/GEF*-act-ras ENZYME n addmsg /kinetics/chain/kinetics[5]/Ras/GDP-Ras /kinetics/chain/kinetics[5]/Ras/GEF*/GEF*-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/GEF* /kinetics/chain/kinetics[5]/Ras/GEF*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/GEF* /kinetics/chain/kinetics[5]/Ras/GEF*/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ras-act-craf /kinetics/chain/kinetics[5]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[5]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[5]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[5]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[5]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[5]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[5]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[5]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[5]/Ras/GTP-Ras REAC sA B addmsg /kinetics/chain/kinetics[5]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[5]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[5]/Ras-act-unphosph-raf /kinetics/chain/kinetics[5]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[4]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[5]/Ras/GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[5]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[5]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[5]/Ras/GTP-Ras /kinetics/chain/kinetics[5]/Ras/GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/GTP-Ras /kinetics/chain/kinetics[5]/Ras/GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[5]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[5]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[5]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[5]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[5]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[5]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[5]/Ras/GDP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[5]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[5]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[4]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[5]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[5]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[5]/Ras/GDP-Ras REAC A B addmsg /kinetics/chain/kinetics[5]/Ras/GDP-Ras /kinetics/chain/kinetics[5]/Ras/GDP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/GDP-Ras /kinetics/chain/kinetics[5]/Ras/GDP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ras/GTP-Ras /kinetics/chain/kinetics[5]/Ras/Ras-intrinsic-GTPase SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/GDP-Ras /kinetics/chain/kinetics[5]/Ras/Ras-intrinsic-GTPase PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ras/GAP* /kinetics/chain/kinetics[5]/Ras/dephosph-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/GAP /kinetics/chain/kinetics[5]/Ras/dephosph-GAP PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[5]/Ras/GAP* MM_PRD pA addmsg /kinetics/chain/kinetics[5]/Ras/dephosph-GAP /kinetics/chain/kinetics[5]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[4]/Ras/GAP*/diff /kinetics/chain/kinetics[5]/Ras/GAP* REAC B A addmsg /kinetics/chain/kinetics[5]/Ras/GAP*/diff /kinetics/chain/kinetics[5]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[5]/Ras/GAP* /kinetics/chain/kinetics[5]/Ras/GAP*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/GAP* /kinetics/chain/kinetics[5]/Ras/GAP*/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[5]/Ras/GAP REAC sA B addmsg /kinetics/chain/kinetics[5]/Ras/dephosph-GAP /kinetics/chain/kinetics[5]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[5]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[5]/Ras/GAP REAC eA B addmsg /kinetics/chain/kinetics[4]/Ras/GAP/diff /kinetics/chain/kinetics[5]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[5]/Ras/GAP/diff /kinetics/chain/kinetics[5]/Ras/GAP REAC A B addmsg /kinetics/chain/kinetics[5]/Ras/GTP-Ras /kinetics/chain/kinetics[5]/Ras/GAP/GAP-inact-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/GAP /kinetics/chain/kinetics[5]/Ras/GAP/GAP-inact-ras ENZYME n addmsg /kinetics/chain/kinetics[5]/Ras/GAP /kinetics/chain/kinetics[5]/Ras/GAP/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/GAP /kinetics/chain/kinetics[5]/Ras/GAP/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ras/inact-GEF /kinetics/chain/kinetics[5]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/CaM-GEF /kinetics/chain/kinetics[5]/Ras/CaM-bind-GEF PRODUCT n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca4 /kinetics/chain/kinetics[5]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[5]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[5]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[5]/Ras/CaM-GEF REAC eA B addmsg /kinetics/chain/kinetics[4]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[5]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[5]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[5]/Ras/CaM-GEF REAC A B addmsg /kinetics/chain/kinetics[5]/Ras/GDP-Ras /kinetics/chain/kinetics[5]/Ras/CaM-GEF/CaM-GEF-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ras/CaM-GEF /kinetics/chain/kinetics[5]/Ras/CaM-GEF/CaM-GEF-act-ras ENZYME n addmsg /kinetics/chain/kinetics[5]/Ras/CaM-GEF /kinetics/chain/kinetics[5]/Ras/CaM-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/CaM-GEF /kinetics/chain/kinetics[5]/Ras/CaM-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[5]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM/diff /kinetics/chain/kinetics[5]/CaM/CaM REAC B A addmsg /kinetics/chain/kinetics[5]/CaM/CaM/diff /kinetics/chain/kinetics[5]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM /kinetics/chain/kinetics[5]/CaM/CaM/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/CaM/CaM /kinetics/chain/kinetics[5]/CaM/CaM/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca3 /kinetics/chain/kinetics[5]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca4 /kinetics/chain/kinetics[5]/CaM/CaM-Ca3-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ca /kinetics/chain/kinetics[5]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[5]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[5]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[5]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[5]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca3 /kinetics/chain/kinetics[5]/CaM/CaM-Ca3/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca3 /kinetics/chain/kinetics[5]/CaM/CaM-Ca3/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[5]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[5]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[5]/PKM/trigger_PKM /kinetics/chain/kinetics[5]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[5]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[5]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca4 /kinetics/chain/kinetics[5]/CaM/CaM-Ca4/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca4 /kinetics/chain/kinetics[5]/CaM/CaM-Ca4/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/CaM/CaM /kinetics/chain/kinetics[5]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca /kinetics/chain/kinetics[5]/CaM/CaM-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ca /kinetics/chain/kinetics[5]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[5]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[5]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[5]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[5]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca2 /kinetics/chain/kinetics[5]/CaM/CaM-Ca2/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca2 /kinetics/chain/kinetics[5]/CaM/CaM-Ca2/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca3 /kinetics/chain/kinetics[5]/CaM/CaM-Ca2-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca2 /kinetics/chain/kinetics[5]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ca /kinetics/chain/kinetics[5]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca2 /kinetics/chain/kinetics[5]/CaM/CaM-Ca-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca /kinetics/chain/kinetics[5]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/Ca /kinetics/chain/kinetics[5]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[5]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[5]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[4]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[5]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[5]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca /kinetics/chain/kinetics[5]/CaM/CaM-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca /kinetics/chain/kinetics[5]/CaM/CaM-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[5]/Ca REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[5]/Ca REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[5]/Ca REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[5]/Ca REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[5]/Ca REAC A B addmsg /kinetics/chain/kinetics[5]/Ca_diff /kinetics/chain/kinetics[5]/Ca REAC B A addmsg /kinetics/chain/kinetics[4]/Ca/diff /kinetics/chain/kinetics[5]/Ca REAC B A addmsg /kinetics/chain/kinetics[5]/Ca/diff /kinetics/chain/kinetics[5]/Ca REAC A B addmsg /kinetics/chain/kinetics[5]/Ca /kinetics/chain/kinetics[5]/Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ca /kinetics/chain/kinetics[5]/Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1 /kinetics/chain/kinetics[5]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[5]/Ras-act-unphosph-raf PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ras/GTP-Ras /kinetics/chain/kinetics[5]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKM/trigger_PKM /kinetics/chain/kinetics[5]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[4]/PKM/Ca_detector/diff /kinetics/chain/kinetics[5]/PKM/Ca_detector REAC B A addmsg /kinetics/chain/kinetics[5]/PKM/Ca_detector/diff /kinetics/chain/kinetics[5]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[5]/PKM/Ca_detector /kinetics/chain/kinetics[5]/PKM/Ca_detector/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKM/Ca_detector /kinetics/chain/kinetics[5]/PKM/Ca_detector/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[5]/PKM/PKM_synthesis REAC eA B addmsg /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[5]/PKM/PKM_synthesis MM_PRD pA addmsg /kinetics/chain/kinetics[5]/PKM/turn_off_activator /kinetics/chain/kinetics[5]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[4]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[5]/PKM/PKM_synthesis REAC B A addmsg /kinetics/chain/kinetics[5]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[5]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[5]/PKM/PKM_synthesis /kinetics/chain/kinetics[5]/PKM/PKM_synthesis/kenz ENZYME n addmsg /kinetics/chain/kinetics[5]/PKM/AA_pool /kinetics/chain/kinetics[5]/PKM/PKM_synthesis/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKM/PKM_synthesis /kinetics/chain/kinetics[5]/PKM/PKM_synthesis/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKM/PKM_synthesis /kinetics/chain/kinetics[5]/PKM/PKM_synthesis/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[5]/PKM/AA_pool REAC sA B addmsg /kinetics/chain/kinetics[5]/PKC/PKM-zeta /kinetics/chain/kinetics[5]/PKM/PKM_degradation SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKM/degraded_PKM /kinetics/chain/kinetics[5]/PKM/PKM_degradation PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKM/PKM_degradation /kinetics/chain/kinetics[5]/PKM/degraded_PKM REAC B A addmsg /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex REAC eA B addmsg /kinetics/chain/kinetics[5]/PKM/trigger_PKM /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[4]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex REAC A B addmsg /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex/kenz ENZYME n addmsg /kinetics/chain/kinetics[5]/PKM/PKM_activator /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[5]/PKM/PKM_activator REAC sA B addmsg /kinetics/chain/kinetics[5]/PKM/turn_off_activator /kinetics/chain/kinetics[5]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[4]/PKM/PKM_activator/diff /kinetics/chain/kinetics[5]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[5]/PKM/PKM_activator/diff /kinetics/chain/kinetics[5]/PKM/PKM_activator REAC A B addmsg /kinetics/chain/kinetics[5]/PKM/PKM_activator /kinetics/chain/kinetics[5]/PKM/PKM_activator/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKM/PKM_activator /kinetics/chain/kinetics[5]/PKM/PKM_activator/diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/PKM/PKM_synthesis /kinetics/chain/kinetics[5]/PKM/turn_off_activator SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKM/PKM_activator /kinetics/chain/kinetics[5]/PKM/turn_off_activator PRODUCT n addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca4 /kinetics/chain/kinetics[5]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKM/Ca_detector /kinetics/chain/kinetics[5]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex /kinetics/chain/kinetics[5]/PKM/trigger_PKM PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ca_diff /kinetics/chain/kinetics[5]/Ca_input REAC A B addmsg /kinetics/chain/kinetics[5]/Ca /kinetics/chain/kinetics[5]/Ca_diff PRODUCT n addmsg /kinetics/chain/kinetics[5]/Ca_input /kinetics/chain/kinetics[5]/Ca_diff SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[6]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[6]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[6]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[6]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[6]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[6]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca /kinetics/chain/kinetics[6]/PKC/PKC-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca /kinetics/chain/kinetics[6]/PKC/PKC-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca /kinetics/chain/kinetics[6]/PKC/PKC-act-by-Ca PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic /kinetics/chain/kinetics[6]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ca /kinetics/chain/kinetics[6]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca /kinetics/chain/kinetics[6]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[6]/PKC/PKC-act-by-DAG PRODUCT n addmsg /kinetics/chain/kinetics[6]/DAG /kinetics/chain/kinetics[6]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca /kinetics/chain/kinetics[6]/PKC/PKC-Ca-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[6]/PKC/PKC-Ca-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[6]/PKC/PKC-DAG-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[6]/PKC/PKC-DAG-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[6]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[6]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[6]/PKC/PKC-Ca-memb* REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[6]/PKC/PKC-Ca-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[6]/PKC/PKC-Ca-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[6]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[5]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[6]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[6]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[6]/PKC/PKC-DAG-memb* REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[6]/PKC/PKC-DAG-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[6]/PKC/PKC-DAG-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[6]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-DAG /kinetics/chain/kinetics[6]/PKC/PKC-n-DAG PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic /kinetics/chain/kinetics[6]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/DAG /kinetics/chain/kinetics[6]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-n-DAG /kinetics/chain/kinetics[6]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[5]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[6]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[6]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[6]/PKC/PKC-DAG REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKC-DAG /kinetics/chain/kinetics[6]/PKC/PKC-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-DAG /kinetics/chain/kinetics[6]/PKC/PKC-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKC-n-DAG /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic REAC B A addmsg /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[6]/PKC/PKM-zeta MM_PRD pA addmsg /kinetics/chain/kinetics[6]/PKM/PKM_degradation /kinetics/chain/kinetics[6]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[5]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[6]/PKC/PKM-zeta REAC B A addmsg /kinetics/chain/kinetics[6]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[6]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKM-zeta /kinetics/chain/kinetics[6]/PKC/PKM-zeta/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKM-zeta /kinetics/chain/kinetics[6]/PKC/PKM-zeta/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[6]/DAG REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKC-n-DAG /kinetics/chain/kinetics[6]/DAG REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[6]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[6]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[6]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[6]/PKC/PKM-zeta /kinetics/chain/kinetics[6]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[6]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[6]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[6]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[6]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[6]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[6]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[6]/PKC-active /kinetics/chain/kinetics[6]/PKC-active/PKC-act-raf ENZYME n addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1 /kinetics/chain/kinetics[6]/PKC-active/PKC-act-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC-active /kinetics/chain/kinetics[6]/PKC-active/PKC-inact-GAP ENZYME n addmsg /kinetics/chain/kinetics[6]/Ras/GAP /kinetics/chain/kinetics[6]/PKC-active/PKC-inact-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC-active /kinetics/chain/kinetics[6]/PKC-active/PKC-act-GEF ENZYME n addmsg /kinetics/chain/kinetics[6]/Ras/inact-GEF /kinetics/chain/kinetics[6]/PKC-active/PKC-act-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[6]/MAPK* REAC eA B addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[6]/MAPK* MM_PRD pA addmsg /kinetics/chain/kinetics[6]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[6]/MAPK* REAC sA B addmsg /kinetics/chain/kinetics[5]/MAPK*/diff /kinetics/chain/kinetics[6]/MAPK* REAC B A addmsg /kinetics/chain/kinetics[6]/MAPK*/diff /kinetics/chain/kinetics[6]/MAPK* REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK* /kinetics/chain/kinetics[6]/MAPK*/MAPK*-feedback ENZYME n addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1* /kinetics/chain/kinetics[6]/MAPK*/MAPK*-feedback SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK* /kinetics/chain/kinetics[6]/MAPK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK* /kinetics/chain/kinetics[6]/MAPK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[6]/MAPK/craf-1 REAC sA B addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[6]/MAPK/craf-1 MM_PRD pA addmsg /kinetics/chain/kinetics[6]/Ras-act-unphosph-raf /kinetics/chain/kinetics[6]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1/diff /kinetics/chain/kinetics[6]/MAPK/craf-1 REAC B A addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1/diff /kinetics/chain/kinetics[6]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1 /kinetics/chain/kinetics[6]/MAPK/craf-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1 /kinetics/chain/kinetics[6]/MAPK/craf-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[6]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[6]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[6]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[6]/Ras-act-craf /kinetics/chain/kinetics[6]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[6]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[6]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1*/diff /kinetics/chain/kinetics[6]/MAPK/craf-1* REAC B A addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1*/diff /kinetics/chain/kinetics[6]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1* /kinetics/chain/kinetics[6]/MAPK/craf-1*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1* /kinetics/chain/kinetics[6]/MAPK/craf-1*/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[6]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[6]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[6]/MAPK/MAPKK MM_PRD pA addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK/diff /kinetics/chain/kinetics[6]/MAPK/MAPKK REAC B A addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK/diff /kinetics/chain/kinetics[6]/MAPK/MAPKK REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK /kinetics/chain/kinetics[6]/MAPK/MAPKK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK /kinetics/chain/kinetics[6]/MAPK/MAPKK/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[6]/MAPK/MAPK REAC sA B addmsg /kinetics/chain/kinetics[6]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[6]/MAPK/MAPK MM_PRD pA addmsg /kinetics/chain/kinetics[5]/MAPK/MAPK/diff /kinetics/chain/kinetics[6]/MAPK/MAPK REAC B A addmsg /kinetics/chain/kinetics[6]/MAPK/MAPK/diff /kinetics/chain/kinetics[6]/MAPK/MAPK REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK/MAPK /kinetics/chain/kinetics[6]/MAPK/MAPK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPK /kinetics/chain/kinetics[6]/MAPK/MAPK/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[6]/MAPK/craf-1** MM_PRD pA addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[6]/MAPK/craf-1** REAC sA B addmsg /kinetics/chain/kinetics[5]/MAPK/craf-1**/diff /kinetics/chain/kinetics[6]/MAPK/craf-1** REAC B A addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1**/diff /kinetics/chain/kinetics[6]/MAPK/craf-1** REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1** /kinetics/chain/kinetics[6]/MAPK/craf-1**/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1** /kinetics/chain/kinetics[6]/MAPK/craf-1**/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[6]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[6]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[5]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr REAC B A addmsg /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[6]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[6]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[6]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[6]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[6]/MAPK/MAPKK* REAC sA B addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[6]/MAPK/MAPKK* REAC B A addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[6]/MAPK/MAPKK* REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK/MAPK /kinetics/chain/kinetics[6]/MAPK/MAPKK*/MAPKKtyr SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK* /kinetics/chain/kinetics[6]/MAPK/MAPKK*/MAPKKtyr ENZYME n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr /kinetics/chain/kinetics[6]/MAPK/MAPKK*/MAPKKthr SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK* /kinetics/chain/kinetics[6]/MAPK/MAPKK*/MAPKKthr ENZYME n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK* /kinetics/chain/kinetics[6]/MAPK/MAPKK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK* /kinetics/chain/kinetics[6]/MAPK/MAPKK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[5]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser REAC B A addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[6]/Ras-act-unphosph-raf /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[5]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[6]/Ras-act-craf /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[5]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[6]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[6]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[6]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[5]/MKP-1/diff /kinetics/chain/kinetics[6]/MKP-1 REAC B A addmsg /kinetics/chain/kinetics[6]/MKP-1/diff /kinetics/chain/kinetics[6]/MKP-1 REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr /kinetics/chain/kinetics[6]/MKP-1/MKP1-tyr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MKP-1 /kinetics/chain/kinetics[6]/MKP-1/MKP1-tyr-deph ENZYME n addmsg /kinetics/chain/kinetics[6]/MAPK* /kinetics/chain/kinetics[6]/MKP-1/MKP1-thr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MKP-1 /kinetics/chain/kinetics[6]/MKP-1/MKP1-thr-deph ENZYME n addmsg /kinetics/chain/kinetics[6]/MKP-1 /kinetics/chain/kinetics[6]/MKP-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MKP-1 /kinetics/chain/kinetics[6]/MKP-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1* /kinetics/chain/kinetics[6]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[6]/Ras-act-craf PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ras/GTP-Ras /kinetics/chain/kinetics[6]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[6]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[6]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[6]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[6]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[5]/PPhosphatase2A/diff /kinetics/chain/kinetics[6]/PPhosphatase2A REAC B A addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/diff /kinetics/chain/kinetics[6]/PPhosphatase2A REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1* /kinetics/chain/kinetics[6]/PPhosphatase2A/craf-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A /kinetics/chain/kinetics[6]/PPhosphatase2A/craf-deph ENZYME n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK* /kinetics/chain/kinetics[6]/PPhosphatase2A/MAPKK-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A /kinetics/chain/kinetics[6]/PPhosphatase2A/MAPKK-deph ENZYME n addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser /kinetics/chain/kinetics[6]/PPhosphatase2A/MAPKK-deph-ser SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A /kinetics/chain/kinetics[6]/PPhosphatase2A/MAPKK-deph-ser ENZYME n addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1** /kinetics/chain/kinetics[6]/PPhosphatase2A/craf**-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A /kinetics/chain/kinetics[6]/PPhosphatase2A/craf**-deph ENZYME n addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A /kinetics/chain/kinetics[6]/PPhosphatase2A/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A /kinetics/chain/kinetics[6]/PPhosphatase2A/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ras/inact-GEF /kinetics/chain/kinetics[6]/Ras/dephosph-GEF PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ras/GEF* /kinetics/chain/kinetics[6]/Ras/dephosph-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[6]/Ras/inact-GEF REAC sA B addmsg /kinetics/chain/kinetics[6]/Ras/dephosph-GEF /kinetics/chain/kinetics[6]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[6]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[6]/Ras/inact-GEF REAC eA B addmsg /kinetics/chain/kinetics[6]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[6]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[5]/Ras/inact-GEF/diff /kinetics/chain/kinetics[6]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[6]/Ras/inact-GEF/diff /kinetics/chain/kinetics[6]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[6]/Ras/inact-GEF /kinetics/chain/kinetics[6]/Ras/inact-GEF/basal_GEF_activity ENZYME n addmsg /kinetics/chain/kinetics[6]/Ras/GDP-Ras /kinetics/chain/kinetics[6]/Ras/inact-GEF/basal_GEF_activity SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/inact-GEF /kinetics/chain/kinetics[6]/Ras/inact-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/inact-GEF /kinetics/chain/kinetics[6]/Ras/inact-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[6]/Ras/GEF* MM_PRD pA addmsg /kinetics/chain/kinetics[6]/Ras/dephosph-GEF /kinetics/chain/kinetics[6]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[6]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[6]/Ras/GEF* REAC eA B addmsg /kinetics/chain/kinetics[5]/Ras/GEF*/diff /kinetics/chain/kinetics[6]/Ras/GEF* REAC B A addmsg /kinetics/chain/kinetics[6]/Ras/GEF*/diff /kinetics/chain/kinetics[6]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[6]/Ras/GEF* /kinetics/chain/kinetics[6]/Ras/GEF*/GEF*-act-ras ENZYME n addmsg /kinetics/chain/kinetics[6]/Ras/GDP-Ras /kinetics/chain/kinetics[6]/Ras/GEF*/GEF*-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/GEF* /kinetics/chain/kinetics[6]/Ras/GEF*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/GEF* /kinetics/chain/kinetics[6]/Ras/GEF*/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ras-act-craf /kinetics/chain/kinetics[6]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[6]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[6]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[6]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[6]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[6]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[6]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[6]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[6]/Ras/GTP-Ras REAC sA B addmsg /kinetics/chain/kinetics[6]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[6]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[6]/Ras-act-unphosph-raf /kinetics/chain/kinetics[6]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[5]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[6]/Ras/GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[6]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[6]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[6]/Ras/GTP-Ras /kinetics/chain/kinetics[6]/Ras/GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/GTP-Ras /kinetics/chain/kinetics[6]/Ras/GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[6]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[6]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[6]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[6]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[6]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[6]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[6]/Ras/GDP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[6]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[6]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[5]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[6]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[6]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[6]/Ras/GDP-Ras REAC A B addmsg /kinetics/chain/kinetics[6]/Ras/GDP-Ras /kinetics/chain/kinetics[6]/Ras/GDP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/GDP-Ras /kinetics/chain/kinetics[6]/Ras/GDP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ras/GTP-Ras /kinetics/chain/kinetics[6]/Ras/Ras-intrinsic-GTPase SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/GDP-Ras /kinetics/chain/kinetics[6]/Ras/Ras-intrinsic-GTPase PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ras/GAP* /kinetics/chain/kinetics[6]/Ras/dephosph-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/GAP /kinetics/chain/kinetics[6]/Ras/dephosph-GAP PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[6]/Ras/GAP* MM_PRD pA addmsg /kinetics/chain/kinetics[6]/Ras/dephosph-GAP /kinetics/chain/kinetics[6]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[5]/Ras/GAP*/diff /kinetics/chain/kinetics[6]/Ras/GAP* REAC B A addmsg /kinetics/chain/kinetics[6]/Ras/GAP*/diff /kinetics/chain/kinetics[6]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[6]/Ras/GAP* /kinetics/chain/kinetics[6]/Ras/GAP*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/GAP* /kinetics/chain/kinetics[6]/Ras/GAP*/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[6]/Ras/GAP REAC sA B addmsg /kinetics/chain/kinetics[6]/Ras/dephosph-GAP /kinetics/chain/kinetics[6]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[6]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[6]/Ras/GAP REAC eA B addmsg /kinetics/chain/kinetics[5]/Ras/GAP/diff /kinetics/chain/kinetics[6]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[6]/Ras/GAP/diff /kinetics/chain/kinetics[6]/Ras/GAP REAC A B addmsg /kinetics/chain/kinetics[6]/Ras/GTP-Ras /kinetics/chain/kinetics[6]/Ras/GAP/GAP-inact-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/GAP /kinetics/chain/kinetics[6]/Ras/GAP/GAP-inact-ras ENZYME n addmsg /kinetics/chain/kinetics[6]/Ras/GAP /kinetics/chain/kinetics[6]/Ras/GAP/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/GAP /kinetics/chain/kinetics[6]/Ras/GAP/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ras/inact-GEF /kinetics/chain/kinetics[6]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/CaM-GEF /kinetics/chain/kinetics[6]/Ras/CaM-bind-GEF PRODUCT n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca4 /kinetics/chain/kinetics[6]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[6]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[6]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[6]/Ras/CaM-GEF REAC eA B addmsg /kinetics/chain/kinetics[5]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[6]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[6]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[6]/Ras/CaM-GEF REAC A B addmsg /kinetics/chain/kinetics[6]/Ras/GDP-Ras /kinetics/chain/kinetics[6]/Ras/CaM-GEF/CaM-GEF-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ras/CaM-GEF /kinetics/chain/kinetics[6]/Ras/CaM-GEF/CaM-GEF-act-ras ENZYME n addmsg /kinetics/chain/kinetics[6]/Ras/CaM-GEF /kinetics/chain/kinetics[6]/Ras/CaM-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/CaM-GEF /kinetics/chain/kinetics[6]/Ras/CaM-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[6]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM/diff /kinetics/chain/kinetics[6]/CaM/CaM REAC B A addmsg /kinetics/chain/kinetics[6]/CaM/CaM/diff /kinetics/chain/kinetics[6]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM /kinetics/chain/kinetics[6]/CaM/CaM/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/CaM/CaM /kinetics/chain/kinetics[6]/CaM/CaM/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca3 /kinetics/chain/kinetics[6]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca4 /kinetics/chain/kinetics[6]/CaM/CaM-Ca3-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ca /kinetics/chain/kinetics[6]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[6]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[6]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[6]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[6]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca3 /kinetics/chain/kinetics[6]/CaM/CaM-Ca3/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca3 /kinetics/chain/kinetics[6]/CaM/CaM-Ca3/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[6]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[6]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[6]/PKM/trigger_PKM /kinetics/chain/kinetics[6]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[6]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[6]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca4 /kinetics/chain/kinetics[6]/CaM/CaM-Ca4/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca4 /kinetics/chain/kinetics[6]/CaM/CaM-Ca4/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/CaM/CaM /kinetics/chain/kinetics[6]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca /kinetics/chain/kinetics[6]/CaM/CaM-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ca /kinetics/chain/kinetics[6]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[6]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[6]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[6]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[6]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca2 /kinetics/chain/kinetics[6]/CaM/CaM-Ca2/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca2 /kinetics/chain/kinetics[6]/CaM/CaM-Ca2/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca3 /kinetics/chain/kinetics[6]/CaM/CaM-Ca2-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca2 /kinetics/chain/kinetics[6]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ca /kinetics/chain/kinetics[6]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca2 /kinetics/chain/kinetics[6]/CaM/CaM-Ca-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca /kinetics/chain/kinetics[6]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/Ca /kinetics/chain/kinetics[6]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[6]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[6]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[5]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[6]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[6]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca /kinetics/chain/kinetics[6]/CaM/CaM-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca /kinetics/chain/kinetics[6]/CaM/CaM-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[6]/Ca REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[6]/Ca REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[6]/Ca REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[6]/Ca REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[6]/Ca REAC A B addmsg /kinetics/chain/kinetics[6]/Ca_diff /kinetics/chain/kinetics[6]/Ca REAC B A addmsg /kinetics/chain/kinetics[5]/Ca/diff /kinetics/chain/kinetics[6]/Ca REAC B A addmsg /kinetics/chain/kinetics[6]/Ca/diff /kinetics/chain/kinetics[6]/Ca REAC A B addmsg /kinetics/chain/kinetics[6]/Ca /kinetics/chain/kinetics[6]/Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ca /kinetics/chain/kinetics[6]/Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1 /kinetics/chain/kinetics[6]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[6]/Ras-act-unphosph-raf PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ras/GTP-Ras /kinetics/chain/kinetics[6]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKM/trigger_PKM /kinetics/chain/kinetics[6]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[5]/PKM/Ca_detector/diff /kinetics/chain/kinetics[6]/PKM/Ca_detector REAC B A addmsg /kinetics/chain/kinetics[6]/PKM/Ca_detector/diff /kinetics/chain/kinetics[6]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[6]/PKM/Ca_detector /kinetics/chain/kinetics[6]/PKM/Ca_detector/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKM/Ca_detector /kinetics/chain/kinetics[6]/PKM/Ca_detector/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[6]/PKM/PKM_synthesis REAC eA B addmsg /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[6]/PKM/PKM_synthesis MM_PRD pA addmsg /kinetics/chain/kinetics[6]/PKM/turn_off_activator /kinetics/chain/kinetics[6]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[5]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[6]/PKM/PKM_synthesis REAC B A addmsg /kinetics/chain/kinetics[6]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[6]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[6]/PKM/PKM_synthesis /kinetics/chain/kinetics[6]/PKM/PKM_synthesis/kenz ENZYME n addmsg /kinetics/chain/kinetics[6]/PKM/AA_pool /kinetics/chain/kinetics[6]/PKM/PKM_synthesis/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKM/PKM_synthesis /kinetics/chain/kinetics[6]/PKM/PKM_synthesis/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKM/PKM_synthesis /kinetics/chain/kinetics[6]/PKM/PKM_synthesis/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[6]/PKM/AA_pool REAC sA B addmsg /kinetics/chain/kinetics[6]/PKC/PKM-zeta /kinetics/chain/kinetics[6]/PKM/PKM_degradation SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKM/degraded_PKM /kinetics/chain/kinetics[6]/PKM/PKM_degradation PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKM/PKM_degradation /kinetics/chain/kinetics[6]/PKM/degraded_PKM REAC B A addmsg /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex REAC eA B addmsg /kinetics/chain/kinetics[6]/PKM/trigger_PKM /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[5]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex REAC A B addmsg /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex/kenz ENZYME n addmsg /kinetics/chain/kinetics[6]/PKM/PKM_activator /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[6]/PKM/PKM_activator REAC sA B addmsg /kinetics/chain/kinetics[6]/PKM/turn_off_activator /kinetics/chain/kinetics[6]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[5]/PKM/PKM_activator/diff /kinetics/chain/kinetics[6]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[6]/PKM/PKM_activator/diff /kinetics/chain/kinetics[6]/PKM/PKM_activator REAC A B addmsg /kinetics/chain/kinetics[6]/PKM/PKM_activator /kinetics/chain/kinetics[6]/PKM/PKM_activator/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKM/PKM_activator /kinetics/chain/kinetics[6]/PKM/PKM_activator/diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/PKM/PKM_synthesis /kinetics/chain/kinetics[6]/PKM/turn_off_activator SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKM/PKM_activator /kinetics/chain/kinetics[6]/PKM/turn_off_activator PRODUCT n addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca4 /kinetics/chain/kinetics[6]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKM/Ca_detector /kinetics/chain/kinetics[6]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex /kinetics/chain/kinetics[6]/PKM/trigger_PKM PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ca_diff /kinetics/chain/kinetics[6]/Ca_input REAC A B addmsg /kinetics/chain/kinetics[6]/Ca /kinetics/chain/kinetics[6]/Ca_diff PRODUCT n addmsg /kinetics/chain/kinetics[6]/Ca_input /kinetics/chain/kinetics[6]/Ca_diff SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[7]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[7]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[7]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[7]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[7]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[7]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca /kinetics/chain/kinetics[7]/PKC/PKC-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca /kinetics/chain/kinetics[7]/PKC/PKC-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca /kinetics/chain/kinetics[7]/PKC/PKC-act-by-Ca PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic /kinetics/chain/kinetics[7]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ca /kinetics/chain/kinetics[7]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca /kinetics/chain/kinetics[7]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[7]/PKC/PKC-act-by-DAG PRODUCT n addmsg /kinetics/chain/kinetics[7]/DAG /kinetics/chain/kinetics[7]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca /kinetics/chain/kinetics[7]/PKC/PKC-Ca-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[7]/PKC/PKC-Ca-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[7]/PKC/PKC-DAG-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[7]/PKC/PKC-DAG-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[7]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[7]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[7]/PKC/PKC-Ca-memb* REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[7]/PKC/PKC-Ca-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[7]/PKC/PKC-Ca-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[7]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[6]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[7]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[7]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[7]/PKC/PKC-DAG-memb* REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[7]/PKC/PKC-DAG-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[7]/PKC/PKC-DAG-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[7]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-DAG /kinetics/chain/kinetics[7]/PKC/PKC-n-DAG PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic /kinetics/chain/kinetics[7]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/DAG /kinetics/chain/kinetics[7]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-n-DAG /kinetics/chain/kinetics[7]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[6]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[7]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[7]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[7]/PKC/PKC-DAG REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKC-DAG /kinetics/chain/kinetics[7]/PKC/PKC-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-DAG /kinetics/chain/kinetics[7]/PKC/PKC-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKC-n-DAG /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic REAC B A addmsg /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[7]/PKC/PKM-zeta MM_PRD pA addmsg /kinetics/chain/kinetics[7]/PKM/PKM_degradation /kinetics/chain/kinetics[7]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[6]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[7]/PKC/PKM-zeta REAC B A addmsg /kinetics/chain/kinetics[7]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[7]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKM-zeta /kinetics/chain/kinetics[7]/PKC/PKM-zeta/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKM-zeta /kinetics/chain/kinetics[7]/PKC/PKM-zeta/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[7]/DAG REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKC-n-DAG /kinetics/chain/kinetics[7]/DAG REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[7]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[7]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[7]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[7]/PKC/PKM-zeta /kinetics/chain/kinetics[7]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[7]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[7]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[7]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[7]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[7]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[7]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[7]/PKC-active /kinetics/chain/kinetics[7]/PKC-active/PKC-act-raf ENZYME n addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1 /kinetics/chain/kinetics[7]/PKC-active/PKC-act-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC-active /kinetics/chain/kinetics[7]/PKC-active/PKC-inact-GAP ENZYME n addmsg /kinetics/chain/kinetics[7]/Ras/GAP /kinetics/chain/kinetics[7]/PKC-active/PKC-inact-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC-active /kinetics/chain/kinetics[7]/PKC-active/PKC-act-GEF ENZYME n addmsg /kinetics/chain/kinetics[7]/Ras/inact-GEF /kinetics/chain/kinetics[7]/PKC-active/PKC-act-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[7]/MAPK* REAC eA B addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[7]/MAPK* MM_PRD pA addmsg /kinetics/chain/kinetics[7]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[7]/MAPK* REAC sA B addmsg /kinetics/chain/kinetics[6]/MAPK*/diff /kinetics/chain/kinetics[7]/MAPK* REAC B A addmsg /kinetics/chain/kinetics[7]/MAPK*/diff /kinetics/chain/kinetics[7]/MAPK* REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK* /kinetics/chain/kinetics[7]/MAPK*/MAPK*-feedback ENZYME n addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1* /kinetics/chain/kinetics[7]/MAPK*/MAPK*-feedback SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK* /kinetics/chain/kinetics[7]/MAPK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK* /kinetics/chain/kinetics[7]/MAPK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[7]/MAPK/craf-1 REAC sA B addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[7]/MAPK/craf-1 MM_PRD pA addmsg /kinetics/chain/kinetics[7]/Ras-act-unphosph-raf /kinetics/chain/kinetics[7]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1/diff /kinetics/chain/kinetics[7]/MAPK/craf-1 REAC B A addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1/diff /kinetics/chain/kinetics[7]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1 /kinetics/chain/kinetics[7]/MAPK/craf-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1 /kinetics/chain/kinetics[7]/MAPK/craf-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[7]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[7]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[7]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[7]/Ras-act-craf /kinetics/chain/kinetics[7]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[7]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[7]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1*/diff /kinetics/chain/kinetics[7]/MAPK/craf-1* REAC B A addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1*/diff /kinetics/chain/kinetics[7]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1* /kinetics/chain/kinetics[7]/MAPK/craf-1*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1* /kinetics/chain/kinetics[7]/MAPK/craf-1*/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[7]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[7]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[7]/MAPK/MAPKK MM_PRD pA addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK/diff /kinetics/chain/kinetics[7]/MAPK/MAPKK REAC B A addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK/diff /kinetics/chain/kinetics[7]/MAPK/MAPKK REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK /kinetics/chain/kinetics[7]/MAPK/MAPKK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK /kinetics/chain/kinetics[7]/MAPK/MAPKK/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[7]/MAPK/MAPK REAC sA B addmsg /kinetics/chain/kinetics[7]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[7]/MAPK/MAPK MM_PRD pA addmsg /kinetics/chain/kinetics[6]/MAPK/MAPK/diff /kinetics/chain/kinetics[7]/MAPK/MAPK REAC B A addmsg /kinetics/chain/kinetics[7]/MAPK/MAPK/diff /kinetics/chain/kinetics[7]/MAPK/MAPK REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK/MAPK /kinetics/chain/kinetics[7]/MAPK/MAPK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPK /kinetics/chain/kinetics[7]/MAPK/MAPK/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[7]/MAPK/craf-1** MM_PRD pA addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[7]/MAPK/craf-1** REAC sA B addmsg /kinetics/chain/kinetics[6]/MAPK/craf-1**/diff /kinetics/chain/kinetics[7]/MAPK/craf-1** REAC B A addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1**/diff /kinetics/chain/kinetics[7]/MAPK/craf-1** REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1** /kinetics/chain/kinetics[7]/MAPK/craf-1**/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1** /kinetics/chain/kinetics[7]/MAPK/craf-1**/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[7]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[7]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[6]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr REAC B A addmsg /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[7]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[7]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[7]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[7]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[7]/MAPK/MAPKK* REAC sA B addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[7]/MAPK/MAPKK* REAC B A addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[7]/MAPK/MAPKK* REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK/MAPK /kinetics/chain/kinetics[7]/MAPK/MAPKK*/MAPKKtyr SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK* /kinetics/chain/kinetics[7]/MAPK/MAPKK*/MAPKKtyr ENZYME n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr /kinetics/chain/kinetics[7]/MAPK/MAPKK*/MAPKKthr SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK* /kinetics/chain/kinetics[7]/MAPK/MAPKK*/MAPKKthr ENZYME n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK* /kinetics/chain/kinetics[7]/MAPK/MAPKK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK* /kinetics/chain/kinetics[7]/MAPK/MAPKK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[6]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser REAC B A addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[7]/Ras-act-unphosph-raf /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[6]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[7]/Ras-act-craf /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[6]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[7]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[7]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[7]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[6]/MKP-1/diff /kinetics/chain/kinetics[7]/MKP-1 REAC B A addmsg /kinetics/chain/kinetics[7]/MKP-1/diff /kinetics/chain/kinetics[7]/MKP-1 REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr /kinetics/chain/kinetics[7]/MKP-1/MKP1-tyr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MKP-1 /kinetics/chain/kinetics[7]/MKP-1/MKP1-tyr-deph ENZYME n addmsg /kinetics/chain/kinetics[7]/MAPK* /kinetics/chain/kinetics[7]/MKP-1/MKP1-thr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MKP-1 /kinetics/chain/kinetics[7]/MKP-1/MKP1-thr-deph ENZYME n addmsg /kinetics/chain/kinetics[7]/MKP-1 /kinetics/chain/kinetics[7]/MKP-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MKP-1 /kinetics/chain/kinetics[7]/MKP-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1* /kinetics/chain/kinetics[7]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[7]/Ras-act-craf PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ras/GTP-Ras /kinetics/chain/kinetics[7]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[7]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[7]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[7]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[7]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[6]/PPhosphatase2A/diff /kinetics/chain/kinetics[7]/PPhosphatase2A REAC B A addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/diff /kinetics/chain/kinetics[7]/PPhosphatase2A REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1* /kinetics/chain/kinetics[7]/PPhosphatase2A/craf-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A /kinetics/chain/kinetics[7]/PPhosphatase2A/craf-deph ENZYME n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK* /kinetics/chain/kinetics[7]/PPhosphatase2A/MAPKK-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A /kinetics/chain/kinetics[7]/PPhosphatase2A/MAPKK-deph ENZYME n addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser /kinetics/chain/kinetics[7]/PPhosphatase2A/MAPKK-deph-ser SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A /kinetics/chain/kinetics[7]/PPhosphatase2A/MAPKK-deph-ser ENZYME n addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1** /kinetics/chain/kinetics[7]/PPhosphatase2A/craf**-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A /kinetics/chain/kinetics[7]/PPhosphatase2A/craf**-deph ENZYME n addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A /kinetics/chain/kinetics[7]/PPhosphatase2A/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A /kinetics/chain/kinetics[7]/PPhosphatase2A/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ras/inact-GEF /kinetics/chain/kinetics[7]/Ras/dephosph-GEF PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ras/GEF* /kinetics/chain/kinetics[7]/Ras/dephosph-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[7]/Ras/inact-GEF REAC sA B addmsg /kinetics/chain/kinetics[7]/Ras/dephosph-GEF /kinetics/chain/kinetics[7]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[7]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[7]/Ras/inact-GEF REAC eA B addmsg /kinetics/chain/kinetics[7]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[7]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[6]/Ras/inact-GEF/diff /kinetics/chain/kinetics[7]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[7]/Ras/inact-GEF/diff /kinetics/chain/kinetics[7]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[7]/Ras/inact-GEF /kinetics/chain/kinetics[7]/Ras/inact-GEF/basal_GEF_activity ENZYME n addmsg /kinetics/chain/kinetics[7]/Ras/GDP-Ras /kinetics/chain/kinetics[7]/Ras/inact-GEF/basal_GEF_activity SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/inact-GEF /kinetics/chain/kinetics[7]/Ras/inact-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/inact-GEF /kinetics/chain/kinetics[7]/Ras/inact-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[7]/Ras/GEF* MM_PRD pA addmsg /kinetics/chain/kinetics[7]/Ras/dephosph-GEF /kinetics/chain/kinetics[7]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[7]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[7]/Ras/GEF* REAC eA B addmsg /kinetics/chain/kinetics[6]/Ras/GEF*/diff /kinetics/chain/kinetics[7]/Ras/GEF* REAC B A addmsg /kinetics/chain/kinetics[7]/Ras/GEF*/diff /kinetics/chain/kinetics[7]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[7]/Ras/GEF* /kinetics/chain/kinetics[7]/Ras/GEF*/GEF*-act-ras ENZYME n addmsg /kinetics/chain/kinetics[7]/Ras/GDP-Ras /kinetics/chain/kinetics[7]/Ras/GEF*/GEF*-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/GEF* /kinetics/chain/kinetics[7]/Ras/GEF*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/GEF* /kinetics/chain/kinetics[7]/Ras/GEF*/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ras-act-craf /kinetics/chain/kinetics[7]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[7]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[7]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[7]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[7]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[7]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[7]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[7]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[7]/Ras/GTP-Ras REAC sA B addmsg /kinetics/chain/kinetics[7]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[7]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[7]/Ras-act-unphosph-raf /kinetics/chain/kinetics[7]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[6]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[7]/Ras/GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[7]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[7]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[7]/Ras/GTP-Ras /kinetics/chain/kinetics[7]/Ras/GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/GTP-Ras /kinetics/chain/kinetics[7]/Ras/GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[7]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[7]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[7]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[7]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[7]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[7]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[7]/Ras/GDP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[7]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[7]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[6]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[7]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[7]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[7]/Ras/GDP-Ras REAC A B addmsg /kinetics/chain/kinetics[7]/Ras/GDP-Ras /kinetics/chain/kinetics[7]/Ras/GDP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/GDP-Ras /kinetics/chain/kinetics[7]/Ras/GDP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ras/GTP-Ras /kinetics/chain/kinetics[7]/Ras/Ras-intrinsic-GTPase SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/GDP-Ras /kinetics/chain/kinetics[7]/Ras/Ras-intrinsic-GTPase PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ras/GAP* /kinetics/chain/kinetics[7]/Ras/dephosph-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/GAP /kinetics/chain/kinetics[7]/Ras/dephosph-GAP PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[7]/Ras/GAP* MM_PRD pA addmsg /kinetics/chain/kinetics[7]/Ras/dephosph-GAP /kinetics/chain/kinetics[7]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[6]/Ras/GAP*/diff /kinetics/chain/kinetics[7]/Ras/GAP* REAC B A addmsg /kinetics/chain/kinetics[7]/Ras/GAP*/diff /kinetics/chain/kinetics[7]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[7]/Ras/GAP* /kinetics/chain/kinetics[7]/Ras/GAP*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/GAP* /kinetics/chain/kinetics[7]/Ras/GAP*/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[7]/Ras/GAP REAC sA B addmsg /kinetics/chain/kinetics[7]/Ras/dephosph-GAP /kinetics/chain/kinetics[7]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[7]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[7]/Ras/GAP REAC eA B addmsg /kinetics/chain/kinetics[6]/Ras/GAP/diff /kinetics/chain/kinetics[7]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[7]/Ras/GAP/diff /kinetics/chain/kinetics[7]/Ras/GAP REAC A B addmsg /kinetics/chain/kinetics[7]/Ras/GTP-Ras /kinetics/chain/kinetics[7]/Ras/GAP/GAP-inact-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/GAP /kinetics/chain/kinetics[7]/Ras/GAP/GAP-inact-ras ENZYME n addmsg /kinetics/chain/kinetics[7]/Ras/GAP /kinetics/chain/kinetics[7]/Ras/GAP/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/GAP /kinetics/chain/kinetics[7]/Ras/GAP/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ras/inact-GEF /kinetics/chain/kinetics[7]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/CaM-GEF /kinetics/chain/kinetics[7]/Ras/CaM-bind-GEF PRODUCT n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca4 /kinetics/chain/kinetics[7]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[7]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[7]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[7]/Ras/CaM-GEF REAC eA B addmsg /kinetics/chain/kinetics[6]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[7]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[7]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[7]/Ras/CaM-GEF REAC A B addmsg /kinetics/chain/kinetics[7]/Ras/GDP-Ras /kinetics/chain/kinetics[7]/Ras/CaM-GEF/CaM-GEF-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ras/CaM-GEF /kinetics/chain/kinetics[7]/Ras/CaM-GEF/CaM-GEF-act-ras ENZYME n addmsg /kinetics/chain/kinetics[7]/Ras/CaM-GEF /kinetics/chain/kinetics[7]/Ras/CaM-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/CaM-GEF /kinetics/chain/kinetics[7]/Ras/CaM-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[7]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM/diff /kinetics/chain/kinetics[7]/CaM/CaM REAC B A addmsg /kinetics/chain/kinetics[7]/CaM/CaM/diff /kinetics/chain/kinetics[7]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM /kinetics/chain/kinetics[7]/CaM/CaM/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/CaM/CaM /kinetics/chain/kinetics[7]/CaM/CaM/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca3 /kinetics/chain/kinetics[7]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca4 /kinetics/chain/kinetics[7]/CaM/CaM-Ca3-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ca /kinetics/chain/kinetics[7]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[7]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[7]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[7]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[7]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca3 /kinetics/chain/kinetics[7]/CaM/CaM-Ca3/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca3 /kinetics/chain/kinetics[7]/CaM/CaM-Ca3/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[7]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[7]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[7]/PKM/trigger_PKM /kinetics/chain/kinetics[7]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[7]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[7]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca4 /kinetics/chain/kinetics[7]/CaM/CaM-Ca4/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca4 /kinetics/chain/kinetics[7]/CaM/CaM-Ca4/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/CaM/CaM /kinetics/chain/kinetics[7]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca /kinetics/chain/kinetics[7]/CaM/CaM-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ca /kinetics/chain/kinetics[7]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[7]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[7]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[7]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[7]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca2 /kinetics/chain/kinetics[7]/CaM/CaM-Ca2/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca2 /kinetics/chain/kinetics[7]/CaM/CaM-Ca2/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca3 /kinetics/chain/kinetics[7]/CaM/CaM-Ca2-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca2 /kinetics/chain/kinetics[7]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ca /kinetics/chain/kinetics[7]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca2 /kinetics/chain/kinetics[7]/CaM/CaM-Ca-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca /kinetics/chain/kinetics[7]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/Ca /kinetics/chain/kinetics[7]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[7]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[7]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[6]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[7]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[7]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca /kinetics/chain/kinetics[7]/CaM/CaM-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca /kinetics/chain/kinetics[7]/CaM/CaM-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[7]/Ca REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[7]/Ca REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[7]/Ca REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[7]/Ca REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[7]/Ca REAC A B addmsg /kinetics/chain/kinetics[7]/Ca_diff /kinetics/chain/kinetics[7]/Ca REAC B A addmsg /kinetics/chain/kinetics[6]/Ca/diff /kinetics/chain/kinetics[7]/Ca REAC B A addmsg /kinetics/chain/kinetics[7]/Ca/diff /kinetics/chain/kinetics[7]/Ca REAC A B addmsg /kinetics/chain/kinetics[7]/Ca /kinetics/chain/kinetics[7]/Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ca /kinetics/chain/kinetics[7]/Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1 /kinetics/chain/kinetics[7]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[7]/Ras-act-unphosph-raf PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ras/GTP-Ras /kinetics/chain/kinetics[7]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKM/trigger_PKM /kinetics/chain/kinetics[7]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[6]/PKM/Ca_detector/diff /kinetics/chain/kinetics[7]/PKM/Ca_detector REAC B A addmsg /kinetics/chain/kinetics[7]/PKM/Ca_detector/diff /kinetics/chain/kinetics[7]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[7]/PKM/Ca_detector /kinetics/chain/kinetics[7]/PKM/Ca_detector/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKM/Ca_detector /kinetics/chain/kinetics[7]/PKM/Ca_detector/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[7]/PKM/PKM_synthesis REAC eA B addmsg /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[7]/PKM/PKM_synthesis MM_PRD pA addmsg /kinetics/chain/kinetics[7]/PKM/turn_off_activator /kinetics/chain/kinetics[7]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[6]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[7]/PKM/PKM_synthesis REAC B A addmsg /kinetics/chain/kinetics[7]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[7]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[7]/PKM/PKM_synthesis /kinetics/chain/kinetics[7]/PKM/PKM_synthesis/kenz ENZYME n addmsg /kinetics/chain/kinetics[7]/PKM/AA_pool /kinetics/chain/kinetics[7]/PKM/PKM_synthesis/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKM/PKM_synthesis /kinetics/chain/kinetics[7]/PKM/PKM_synthesis/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKM/PKM_synthesis /kinetics/chain/kinetics[7]/PKM/PKM_synthesis/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[7]/PKM/AA_pool REAC sA B addmsg /kinetics/chain/kinetics[7]/PKC/PKM-zeta /kinetics/chain/kinetics[7]/PKM/PKM_degradation SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKM/degraded_PKM /kinetics/chain/kinetics[7]/PKM/PKM_degradation PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKM/PKM_degradation /kinetics/chain/kinetics[7]/PKM/degraded_PKM REAC B A addmsg /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex REAC eA B addmsg /kinetics/chain/kinetics[7]/PKM/trigger_PKM /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[6]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex REAC A B addmsg /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex/kenz ENZYME n addmsg /kinetics/chain/kinetics[7]/PKM/PKM_activator /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[7]/PKM/PKM_activator REAC sA B addmsg /kinetics/chain/kinetics[7]/PKM/turn_off_activator /kinetics/chain/kinetics[7]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[6]/PKM/PKM_activator/diff /kinetics/chain/kinetics[7]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[7]/PKM/PKM_activator/diff /kinetics/chain/kinetics[7]/PKM/PKM_activator REAC A B addmsg /kinetics/chain/kinetics[7]/PKM/PKM_activator /kinetics/chain/kinetics[7]/PKM/PKM_activator/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKM/PKM_activator /kinetics/chain/kinetics[7]/PKM/PKM_activator/diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/PKM/PKM_synthesis /kinetics/chain/kinetics[7]/PKM/turn_off_activator SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKM/PKM_activator /kinetics/chain/kinetics[7]/PKM/turn_off_activator PRODUCT n addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca4 /kinetics/chain/kinetics[7]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKM/Ca_detector /kinetics/chain/kinetics[7]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex /kinetics/chain/kinetics[7]/PKM/trigger_PKM PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ca_diff /kinetics/chain/kinetics[7]/Ca_input REAC A B addmsg /kinetics/chain/kinetics[7]/Ca /kinetics/chain/kinetics[7]/Ca_diff PRODUCT n addmsg /kinetics/chain/kinetics[7]/Ca_input /kinetics/chain/kinetics[7]/Ca_diff SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[8]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[8]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[8]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[8]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[8]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[8]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca /kinetics/chain/kinetics[8]/PKC/PKC-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca /kinetics/chain/kinetics[8]/PKC/PKC-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca /kinetics/chain/kinetics[8]/PKC/PKC-act-by-Ca PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic /kinetics/chain/kinetics[8]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ca /kinetics/chain/kinetics[8]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca /kinetics/chain/kinetics[8]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[8]/PKC/PKC-act-by-DAG PRODUCT n addmsg /kinetics/chain/kinetics[8]/DAG /kinetics/chain/kinetics[8]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca /kinetics/chain/kinetics[8]/PKC/PKC-Ca-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[8]/PKC/PKC-Ca-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[8]/PKC/PKC-DAG-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[8]/PKC/PKC-DAG-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[8]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[8]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[8]/PKC/PKC-Ca-memb* REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[8]/PKC/PKC-Ca-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[8]/PKC/PKC-Ca-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[8]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[7]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[8]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[8]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[8]/PKC/PKC-DAG-memb* REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[8]/PKC/PKC-DAG-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[8]/PKC/PKC-DAG-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[8]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-DAG /kinetics/chain/kinetics[8]/PKC/PKC-n-DAG PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic /kinetics/chain/kinetics[8]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/DAG /kinetics/chain/kinetics[8]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-n-DAG /kinetics/chain/kinetics[8]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[7]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[8]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[8]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[8]/PKC/PKC-DAG REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKC-DAG /kinetics/chain/kinetics[8]/PKC/PKC-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-DAG /kinetics/chain/kinetics[8]/PKC/PKC-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKC-n-DAG /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic REAC B A addmsg /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-cytosolic /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[8]/PKC/PKM-zeta MM_PRD pA addmsg /kinetics/chain/kinetics[8]/PKM/PKM_degradation /kinetics/chain/kinetics[8]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[7]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[8]/PKC/PKM-zeta REAC B A addmsg /kinetics/chain/kinetics[8]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[8]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKM-zeta /kinetics/chain/kinetics[8]/PKC/PKM-zeta/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKM-zeta /kinetics/chain/kinetics[8]/PKC/PKM-zeta/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[8]/DAG REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKC-n-DAG /kinetics/chain/kinetics[8]/DAG REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[8]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[8]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[8]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[8]/PKC/PKM-zeta /kinetics/chain/kinetics[8]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[8]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[8]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[8]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[8]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[8]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[8]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[8]/PKC-active /kinetics/chain/kinetics[8]/PKC-active/PKC-act-raf ENZYME n addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1 /kinetics/chain/kinetics[8]/PKC-active/PKC-act-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC-active /kinetics/chain/kinetics[8]/PKC-active/PKC-inact-GAP ENZYME n addmsg /kinetics/chain/kinetics[8]/Ras/GAP /kinetics/chain/kinetics[8]/PKC-active/PKC-inact-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC-active /kinetics/chain/kinetics[8]/PKC-active/PKC-act-GEF ENZYME n addmsg /kinetics/chain/kinetics[8]/Ras/inact-GEF /kinetics/chain/kinetics[8]/PKC-active/PKC-act-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[8]/MAPK* REAC eA B addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[8]/MAPK* MM_PRD pA addmsg /kinetics/chain/kinetics[8]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[8]/MAPK* REAC sA B addmsg /kinetics/chain/kinetics[7]/MAPK*/diff /kinetics/chain/kinetics[8]/MAPK* REAC B A addmsg /kinetics/chain/kinetics[8]/MAPK*/diff /kinetics/chain/kinetics[8]/MAPK* REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK* /kinetics/chain/kinetics[8]/MAPK*/MAPK*-feedback ENZYME n addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1* /kinetics/chain/kinetics[8]/MAPK*/MAPK*-feedback SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK* /kinetics/chain/kinetics[8]/MAPK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK* /kinetics/chain/kinetics[8]/MAPK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[8]/MAPK/craf-1 REAC sA B addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[8]/MAPK/craf-1 MM_PRD pA addmsg /kinetics/chain/kinetics[8]/Ras-act-unphosph-raf /kinetics/chain/kinetics[8]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1/diff /kinetics/chain/kinetics[8]/MAPK/craf-1 REAC B A addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1/diff /kinetics/chain/kinetics[8]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1 /kinetics/chain/kinetics[8]/MAPK/craf-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK/craf-1 /kinetics/chain/kinetics[8]/MAPK/craf-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[8]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[8]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[8]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[8]/Ras-act-craf /kinetics/chain/kinetics[8]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[8]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[8]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1*/diff /kinetics/chain/kinetics[8]/MAPK/craf-1* REAC B A addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1*/diff /kinetics/chain/kinetics[8]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1* /kinetics/chain/kinetics[8]/MAPK/craf-1*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK/craf-1* /kinetics/chain/kinetics[8]/MAPK/craf-1*/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[8]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[8]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[8]/MAPK/MAPKK MM_PRD pA addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK/diff /kinetics/chain/kinetics[8]/MAPK/MAPKK REAC B A addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK/diff /kinetics/chain/kinetics[8]/MAPK/MAPKK REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK /kinetics/chain/kinetics[8]/MAPK/MAPKK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK /kinetics/chain/kinetics[8]/MAPK/MAPKK/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[8]/MAPK/MAPK REAC sA B addmsg /kinetics/chain/kinetics[8]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[8]/MAPK/MAPK MM_PRD pA addmsg /kinetics/chain/kinetics[7]/MAPK/MAPK/diff /kinetics/chain/kinetics[8]/MAPK/MAPK REAC B A addmsg /kinetics/chain/kinetics[8]/MAPK/MAPK/diff /kinetics/chain/kinetics[8]/MAPK/MAPK REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK/MAPK /kinetics/chain/kinetics[8]/MAPK/MAPK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK/MAPK /kinetics/chain/kinetics[8]/MAPK/MAPK/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[8]/MAPK/craf-1** MM_PRD pA addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[8]/MAPK/craf-1** REAC sA B addmsg /kinetics/chain/kinetics[7]/MAPK/craf-1**/diff /kinetics/chain/kinetics[8]/MAPK/craf-1** REAC B A addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1**/diff /kinetics/chain/kinetics[8]/MAPK/craf-1** REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1** /kinetics/chain/kinetics[8]/MAPK/craf-1**/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK/craf-1** /kinetics/chain/kinetics[8]/MAPK/craf-1**/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[8]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[8]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[7]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr REAC B A addmsg /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[8]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[8]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[8]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[8]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[8]/MAPK/MAPKK* REAC sA B addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[8]/MAPK/MAPKK* REAC B A addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[8]/MAPK/MAPKK* REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK/MAPK /kinetics/chain/kinetics[8]/MAPK/MAPKK*/MAPKKtyr SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK* /kinetics/chain/kinetics[8]/MAPK/MAPKK*/MAPKKtyr ENZYME n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr /kinetics/chain/kinetics[8]/MAPK/MAPKK*/MAPKKthr SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK* /kinetics/chain/kinetics[8]/MAPK/MAPKK*/MAPKKthr ENZYME n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK* /kinetics/chain/kinetics[8]/MAPK/MAPKK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK* /kinetics/chain/kinetics[8]/MAPK/MAPKK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[7]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser REAC B A addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[8]/Ras-act-unphosph-raf /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[7]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/diff /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[8]/Ras-act-craf /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[7]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/diff /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 ENZYME n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 ENZYME n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[8]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[8]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[8]/MKP-1 REAC eA B addmsg /kinetics/chain/kinetics[7]/MKP-1/diff /kinetics/chain/kinetics[8]/MKP-1 REAC B A addmsg /kinetics/chain/kinetics[8]/MKP-1/diff /kinetics/chain/kinetics[8]/MKP-1 REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr /kinetics/chain/kinetics[8]/MKP-1/MKP1-tyr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MKP-1 /kinetics/chain/kinetics[8]/MKP-1/MKP1-tyr-deph ENZYME n addmsg /kinetics/chain/kinetics[8]/MAPK* /kinetics/chain/kinetics[8]/MKP-1/MKP1-thr-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MKP-1 /kinetics/chain/kinetics[8]/MKP-1/MKP1-thr-deph ENZYME n addmsg /kinetics/chain/kinetics[8]/MKP-1 /kinetics/chain/kinetics[8]/MKP-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MKP-1 /kinetics/chain/kinetics[8]/MKP-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1* /kinetics/chain/kinetics[8]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf*-GTP-Ras /kinetics/chain/kinetics[8]/Ras-act-craf PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ras/GTP-Ras /kinetics/chain/kinetics[8]/Ras-act-craf SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[8]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[8]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[8]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[8]/PPhosphatase2A REAC eA B addmsg /kinetics/chain/kinetics[7]/PPhosphatase2A/diff /kinetics/chain/kinetics[8]/PPhosphatase2A REAC B A addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A/diff /kinetics/chain/kinetics[8]/PPhosphatase2A REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1* /kinetics/chain/kinetics[8]/PPhosphatase2A/craf-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A /kinetics/chain/kinetics[8]/PPhosphatase2A/craf-deph ENZYME n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK* /kinetics/chain/kinetics[8]/PPhosphatase2A/MAPKK-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A /kinetics/chain/kinetics[8]/PPhosphatase2A/MAPKK-deph ENZYME n addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser /kinetics/chain/kinetics[8]/PPhosphatase2A/MAPKK-deph-ser SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A /kinetics/chain/kinetics[8]/PPhosphatase2A/MAPKK-deph-ser ENZYME n addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1** /kinetics/chain/kinetics[8]/PPhosphatase2A/craf**-deph SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A /kinetics/chain/kinetics[8]/PPhosphatase2A/craf**-deph ENZYME n addmsg /kinetics/chain/kinetics[8]/PPhosphatase2A /kinetics/chain/kinetics[8]/PPhosphatase2A/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PPhosphatase2A /kinetics/chain/kinetics[8]/PPhosphatase2A/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ras/inact-GEF /kinetics/chain/kinetics[8]/Ras/dephosph-GEF PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ras/GEF* /kinetics/chain/kinetics[8]/Ras/dephosph-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[8]/Ras/inact-GEF REAC sA B addmsg /kinetics/chain/kinetics[8]/Ras/dephosph-GEF /kinetics/chain/kinetics[8]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[8]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[8]/Ras/inact-GEF REAC eA B addmsg /kinetics/chain/kinetics[8]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[8]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[7]/Ras/inact-GEF/diff /kinetics/chain/kinetics[8]/Ras/inact-GEF REAC B A addmsg /kinetics/chain/kinetics[8]/Ras/inact-GEF/diff /kinetics/chain/kinetics[8]/Ras/inact-GEF REAC A B addmsg /kinetics/chain/kinetics[8]/Ras/inact-GEF /kinetics/chain/kinetics[8]/Ras/inact-GEF/basal_GEF_activity ENZYME n addmsg /kinetics/chain/kinetics[8]/Ras/GDP-Ras /kinetics/chain/kinetics[8]/Ras/inact-GEF/basal_GEF_activity SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/inact-GEF /kinetics/chain/kinetics[8]/Ras/inact-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/Ras/inact-GEF /kinetics/chain/kinetics[8]/Ras/inact-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[8]/Ras/GEF* MM_PRD pA addmsg /kinetics/chain/kinetics[8]/Ras/dephosph-GEF /kinetics/chain/kinetics[8]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[8]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[8]/Ras/GEF* REAC eA B addmsg /kinetics/chain/kinetics[7]/Ras/GEF*/diff /kinetics/chain/kinetics[8]/Ras/GEF* REAC B A addmsg /kinetics/chain/kinetics[8]/Ras/GEF*/diff /kinetics/chain/kinetics[8]/Ras/GEF* REAC A B addmsg /kinetics/chain/kinetics[8]/Ras/GEF* /kinetics/chain/kinetics[8]/Ras/GEF*/GEF*-act-ras ENZYME n addmsg /kinetics/chain/kinetics[8]/Ras/GDP-Ras /kinetics/chain/kinetics[8]/Ras/GEF*/GEF*-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/GEF* /kinetics/chain/kinetics[8]/Ras/GEF*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/Ras/GEF* /kinetics/chain/kinetics[8]/Ras/GEF*/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ras-act-craf /kinetics/chain/kinetics[8]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[8]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[8]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[8]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[8]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[8]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[8]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[8]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[8]/Ras/GTP-Ras REAC sA B addmsg /kinetics/chain/kinetics[8]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[8]/Ras/GTP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[8]/Ras-act-unphosph-raf /kinetics/chain/kinetics[8]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[7]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[8]/Ras/GTP-Ras REAC B A addmsg /kinetics/chain/kinetics[8]/Ras/GTP-Ras/diff /kinetics/chain/kinetics[8]/Ras/GTP-Ras REAC A B addmsg /kinetics/chain/kinetics[8]/Ras/GTP-Ras /kinetics/chain/kinetics[8]/Ras/GTP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/Ras/GTP-Ras /kinetics/chain/kinetics[8]/Ras/GTP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ras/inact-GEF/basal_GEF_activity /kinetics/chain/kinetics[8]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[8]/Ras/GEF*/GEF*-act-ras /kinetics/chain/kinetics[8]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[8]/Ras/Ras-intrinsic-GTPase /kinetics/chain/kinetics[8]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[8]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[8]/Ras/GDP-Ras MM_PRD pA addmsg /kinetics/chain/kinetics[8]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[8]/Ras/GDP-Ras REAC sA B addmsg /kinetics/chain/kinetics[7]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[8]/Ras/GDP-Ras REAC B A addmsg /kinetics/chain/kinetics[8]/Ras/GDP-Ras/diff /kinetics/chain/kinetics[8]/Ras/GDP-Ras REAC A B addmsg /kinetics/chain/kinetics[8]/Ras/GDP-Ras /kinetics/chain/kinetics[8]/Ras/GDP-Ras/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/Ras/GDP-Ras /kinetics/chain/kinetics[8]/Ras/GDP-Ras/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ras/GTP-Ras /kinetics/chain/kinetics[8]/Ras/Ras-intrinsic-GTPase SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/GDP-Ras /kinetics/chain/kinetics[8]/Ras/Ras-intrinsic-GTPase PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ras/GAP* /kinetics/chain/kinetics[8]/Ras/dephosph-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/GAP /kinetics/chain/kinetics[8]/Ras/dephosph-GAP PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[8]/Ras/GAP* MM_PRD pA addmsg /kinetics/chain/kinetics[8]/Ras/dephosph-GAP /kinetics/chain/kinetics[8]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[7]/Ras/GAP*/diff /kinetics/chain/kinetics[8]/Ras/GAP* REAC B A addmsg /kinetics/chain/kinetics[8]/Ras/GAP*/diff /kinetics/chain/kinetics[8]/Ras/GAP* REAC A B addmsg /kinetics/chain/kinetics[8]/Ras/GAP* /kinetics/chain/kinetics[8]/Ras/GAP*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/Ras/GAP* /kinetics/chain/kinetics[8]/Ras/GAP*/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[8]/Ras/GAP REAC sA B addmsg /kinetics/chain/kinetics[8]/Ras/dephosph-GAP /kinetics/chain/kinetics[8]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[8]/Ras/GAP/GAP-inact-ras /kinetics/chain/kinetics[8]/Ras/GAP REAC eA B addmsg /kinetics/chain/kinetics[7]/Ras/GAP/diff /kinetics/chain/kinetics[8]/Ras/GAP REAC B A addmsg /kinetics/chain/kinetics[8]/Ras/GAP/diff /kinetics/chain/kinetics[8]/Ras/GAP REAC A B addmsg /kinetics/chain/kinetics[8]/Ras/GTP-Ras /kinetics/chain/kinetics[8]/Ras/GAP/GAP-inact-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/GAP /kinetics/chain/kinetics[8]/Ras/GAP/GAP-inact-ras ENZYME n addmsg /kinetics/chain/kinetics[8]/Ras/GAP /kinetics/chain/kinetics[8]/Ras/GAP/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/Ras/GAP /kinetics/chain/kinetics[8]/Ras/GAP/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ras/inact-GEF /kinetics/chain/kinetics[8]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/CaM-GEF /kinetics/chain/kinetics[8]/Ras/CaM-bind-GEF PRODUCT n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca4 /kinetics/chain/kinetics[8]/Ras/CaM-bind-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[8]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[8]/Ras/CaM-GEF/CaM-GEF-act-ras /kinetics/chain/kinetics[8]/Ras/CaM-GEF REAC eA B addmsg /kinetics/chain/kinetics[7]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[8]/Ras/CaM-GEF REAC B A addmsg /kinetics/chain/kinetics[8]/Ras/CaM-GEF/diff /kinetics/chain/kinetics[8]/Ras/CaM-GEF REAC A B addmsg /kinetics/chain/kinetics[8]/Ras/GDP-Ras /kinetics/chain/kinetics[8]/Ras/CaM-GEF/CaM-GEF-act-ras SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ras/CaM-GEF /kinetics/chain/kinetics[8]/Ras/CaM-GEF/CaM-GEF-act-ras ENZYME n addmsg /kinetics/chain/kinetics[8]/Ras/CaM-GEF /kinetics/chain/kinetics[8]/Ras/CaM-GEF/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/Ras/CaM-GEF /kinetics/chain/kinetics[8]/Ras/CaM-GEF/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[8]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM/diff /kinetics/chain/kinetics[8]/CaM/CaM REAC B A addmsg /kinetics/chain/kinetics[8]/CaM/CaM/diff /kinetics/chain/kinetics[8]/CaM/CaM REAC A B addmsg /kinetics/chain/kinetics[8]/CaM/CaM /kinetics/chain/kinetics[8]/CaM/CaM/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/CaM/CaM /kinetics/chain/kinetics[8]/CaM/CaM/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca3 /kinetics/chain/kinetics[8]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca4 /kinetics/chain/kinetics[8]/CaM/CaM-Ca3-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ca /kinetics/chain/kinetics[8]/CaM/CaM-Ca3-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[8]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[8]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[8]/CaM/CaM-Ca3 REAC B A addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca3/diff /kinetics/chain/kinetics[8]/CaM/CaM-Ca3 REAC A B addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca3 /kinetics/chain/kinetics[8]/CaM/CaM-Ca3/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/CaM/CaM-Ca3 /kinetics/chain/kinetics[8]/CaM/CaM-Ca3/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ras/CaM-bind-GEF /kinetics/chain/kinetics[8]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[8]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[8]/PKM/trigger_PKM /kinetics/chain/kinetics[8]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[8]/CaM/CaM-Ca4 REAC B A addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca4/diff /kinetics/chain/kinetics[8]/CaM/CaM-Ca4 REAC A B addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca4 /kinetics/chain/kinetics[8]/CaM/CaM-Ca4/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/CaM/CaM-Ca4 /kinetics/chain/kinetics[8]/CaM/CaM-Ca4/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/CaM/CaM /kinetics/chain/kinetics[8]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca /kinetics/chain/kinetics[8]/CaM/CaM-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ca /kinetics/chain/kinetics[8]/CaM/CaM-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[8]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[8]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[8]/CaM/CaM-Ca2 REAC B A addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca2/diff /kinetics/chain/kinetics[8]/CaM/CaM-Ca2 REAC A B addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca2 /kinetics/chain/kinetics[8]/CaM/CaM-Ca2/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/CaM/CaM-Ca2 /kinetics/chain/kinetics[8]/CaM/CaM-Ca2/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca3 /kinetics/chain/kinetics[8]/CaM/CaM-Ca2-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca2 /kinetics/chain/kinetics[8]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ca /kinetics/chain/kinetics[8]/CaM/CaM-Ca2-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca2 /kinetics/chain/kinetics[8]/CaM/CaM-Ca-bind-Ca PRODUCT n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca /kinetics/chain/kinetics[8]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/Ca /kinetics/chain/kinetics[8]/CaM/CaM-Ca-bind-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[8]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[8]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[7]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[8]/CaM/CaM-Ca REAC B A addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca/diff /kinetics/chain/kinetics[8]/CaM/CaM-Ca REAC A B addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca /kinetics/chain/kinetics[8]/CaM/CaM-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/CaM/CaM-Ca /kinetics/chain/kinetics[8]/CaM/CaM-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[8]/Ca REAC A B addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca3-bind-Ca /kinetics/chain/kinetics[8]/Ca REAC A B addmsg /kinetics/chain/kinetics[8]/CaM/CaM-bind-Ca /kinetics/chain/kinetics[8]/Ca REAC A B addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca2-bind-Ca /kinetics/chain/kinetics[8]/Ca REAC A B addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca-bind-Ca /kinetics/chain/kinetics[8]/Ca REAC A B addmsg /kinetics/chain/kinetics[8]/Ca_diff /kinetics/chain/kinetics[8]/Ca REAC B A addmsg /kinetics/chain/kinetics[7]/Ca/diff /kinetics/chain/kinetics[8]/Ca REAC B A addmsg /kinetics/chain/kinetics[8]/Ca/diff /kinetics/chain/kinetics[8]/Ca REAC A B addmsg /kinetics/chain/kinetics[8]/Ca /kinetics/chain/kinetics[8]/Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/Ca /kinetics/chain/kinetics[8]/Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1 /kinetics/chain/kinetics[8]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/MAPK/Raf-GTP-Ras /kinetics/chain/kinetics[8]/Ras-act-unphosph-raf PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ras/GTP-Ras /kinetics/chain/kinetics[8]/Ras-act-unphosph-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKM/trigger_PKM /kinetics/chain/kinetics[8]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[7]/PKM/Ca_detector/diff /kinetics/chain/kinetics[8]/PKM/Ca_detector REAC B A addmsg /kinetics/chain/kinetics[8]/PKM/Ca_detector/diff /kinetics/chain/kinetics[8]/PKM/Ca_detector REAC A B addmsg /kinetics/chain/kinetics[8]/PKM/Ca_detector /kinetics/chain/kinetics[8]/PKM/Ca_detector/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKM/Ca_detector /kinetics/chain/kinetics[8]/PKM/Ca_detector/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[8]/PKM/PKM_synthesis REAC eA B addmsg /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[8]/PKM/PKM_synthesis MM_PRD pA addmsg /kinetics/chain/kinetics[8]/PKM/turn_off_activator /kinetics/chain/kinetics[8]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[7]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[8]/PKM/PKM_synthesis REAC B A addmsg /kinetics/chain/kinetics[8]/PKM/PKM_synthesis/diff /kinetics/chain/kinetics[8]/PKM/PKM_synthesis REAC A B addmsg /kinetics/chain/kinetics[8]/PKM/PKM_synthesis /kinetics/chain/kinetics[8]/PKM/PKM_synthesis/kenz ENZYME n addmsg /kinetics/chain/kinetics[8]/PKM/AA_pool /kinetics/chain/kinetics[8]/PKM/PKM_synthesis/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKM/PKM_synthesis /kinetics/chain/kinetics[8]/PKM/PKM_synthesis/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKM/PKM_synthesis /kinetics/chain/kinetics[8]/PKM/PKM_synthesis/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[8]/PKM/AA_pool REAC sA B addmsg /kinetics/chain/kinetics[8]/PKC/PKM-zeta /kinetics/chain/kinetics[8]/PKM/PKM_degradation SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKM/degraded_PKM /kinetics/chain/kinetics[8]/PKM/PKM_degradation PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKM/PKM_degradation /kinetics/chain/kinetics[8]/PKM/degraded_PKM REAC B A addmsg /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex REAC eA B addmsg /kinetics/chain/kinetics[8]/PKM/trigger_PKM /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[7]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex REAC B A addmsg /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex/diff /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex REAC A B addmsg /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex/kenz ENZYME n addmsg /kinetics/chain/kinetics[8]/PKM/PKM_activator /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex/kenz SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKM/Ca.detector_complex /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex/kenz /kinetics/chain/kinetics[8]/PKM/PKM_activator REAC sA B addmsg /kinetics/chain/kinetics[8]/PKM/turn_off_activator /kinetics/chain/kinetics[8]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[7]/PKM/PKM_activator/diff /kinetics/chain/kinetics[8]/PKM/PKM_activator REAC B A addmsg /kinetics/chain/kinetics[8]/PKM/PKM_activator/diff /kinetics/chain/kinetics[8]/PKM/PKM_activator REAC A B addmsg /kinetics/chain/kinetics[8]/PKM/PKM_activator /kinetics/chain/kinetics[8]/PKM/PKM_activator/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKM/PKM_activator /kinetics/chain/kinetics[8]/PKM/PKM_activator/diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/PKM/PKM_synthesis /kinetics/chain/kinetics[8]/PKM/turn_off_activator SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKM/PKM_activator /kinetics/chain/kinetics[8]/PKM/turn_off_activator PRODUCT n addmsg /kinetics/chain/kinetics[8]/CaM/CaM-Ca4 /kinetics/chain/kinetics[8]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKM/Ca_detector /kinetics/chain/kinetics[8]/PKM/trigger_PKM SUBSTRATE n addmsg /kinetics/chain/kinetics[8]/PKM/Ca.detector_complex /kinetics/chain/kinetics[8]/PKM/trigger_PKM PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ca_diff /kinetics/chain/kinetics[8]/Ca_input REAC A B addmsg /kinetics/chain/kinetics[8]/Ca /kinetics/chain/kinetics[8]/Ca_diff PRODUCT n addmsg /kinetics/chain/kinetics[8]/Ca_input /kinetics/chain/kinetics[8]/Ca_diff SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[9]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[9]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[9]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[9]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[9]/PKC/PKC-Ca REAC B A addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca/diff /kinetics/chain/kinetics[9]/PKC/PKC-Ca REAC A B addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca /kinetics/chain/kinetics[9]/PKC/PKC-Ca/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/PKC/PKC-Ca /kinetics/chain/kinetics[9]/PKC/PKC-Ca/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca /kinetics/chain/kinetics[9]/PKC/PKC-act-by-Ca PRODUCT n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-cytosolic /kinetics/chain/kinetics[9]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/Ca /kinetics/chain/kinetics[9]/PKC/PKC-act-by-Ca SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca /kinetics/chain/kinetics[9]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[9]/PKC/PKC-act-by-DAG PRODUCT n addmsg /kinetics/chain/kinetics[9]/DAG /kinetics/chain/kinetics[9]/PKC/PKC-act-by-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca /kinetics/chain/kinetics[9]/PKC/PKC-Ca-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[9]/PKC/PKC-Ca-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[9]/PKC/PKC-DAG-to-memb PRODUCT n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[9]/PKC/PKC-DAG-to-memb SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca-to-memb /kinetics/chain/kinetics[9]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[9]/PKC/PKC-Ca-memb* REAC B A addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca-memb*/diff /kinetics/chain/kinetics[9]/PKC/PKC-Ca-memb* REAC A B addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[9]/PKC/PKC-Ca-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[9]/PKC/PKC-Ca-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[9]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[8]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[9]/PKC/PKC-DAG-memb* REAC B A addmsg /kinetics/chain/kinetics[9]/PKC/PKC-DAG-memb*/diff /kinetics/chain/kinetics[9]/PKC/PKC-DAG-memb* REAC A B addmsg /kinetics/chain/kinetics[9]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[9]/PKC/PKC-DAG-memb*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[9]/PKC/PKC-DAG-memb*/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[9]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[9]/PKC/PKC-DAG-to-memb /kinetics/chain/kinetics[9]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[9]/PKC/PKC-Ca-DAG REAC B A addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca-DAG/diff /kinetics/chain/kinetics[9]/PKC/PKC-Ca-DAG REAC A B addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[9]/PKC/PKC-Ca-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/PKC/PKC-Ca-DAG /kinetics/chain/kinetics[9]/PKC/PKC-Ca-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-DAG /kinetics/chain/kinetics[9]/PKC/PKC-n-DAG PRODUCT n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-cytosolic /kinetics/chain/kinetics[9]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/DAG /kinetics/chain/kinetics[9]/PKC/PKC-n-DAG SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-n-DAG /kinetics/chain/kinetics[9]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[8]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[9]/PKC/PKC-DAG REAC B A addmsg /kinetics/chain/kinetics[9]/PKC/PKC-DAG/diff /kinetics/chain/kinetics[9]/PKC/PKC-DAG REAC A B addmsg /kinetics/chain/kinetics[9]/PKC/PKC-DAG /kinetics/chain/kinetics[9]/PKC/PKC-DAG/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/PKC/PKC-DAG /kinetics/chain/kinetics[9]/PKC/PKC-DAG/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-act-by-Ca /kinetics/chain/kinetics[9]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[9]/PKC/PKC-n-DAG /kinetics/chain/kinetics[9]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[9]/PKC/PKC-cytosolic REAC B A addmsg /kinetics/chain/kinetics[9]/PKC/PKC-cytosolic/diff /kinetics/chain/kinetics[9]/PKC/PKC-cytosolic REAC A B addmsg /kinetics/chain/kinetics[9]/PKC/PKC-cytosolic /kinetics/chain/kinetics[9]/PKC/PKC-cytosolic/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/PKC/PKC-cytosolic /kinetics/chain/kinetics[9]/PKC/PKC-cytosolic/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/PKM/PKM_synthesis/kenz /kinetics/chain/kinetics[9]/PKC/PKM-zeta MM_PRD pA addmsg /kinetics/chain/kinetics[9]/PKM/PKM_degradation /kinetics/chain/kinetics[9]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[8]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[9]/PKC/PKM-zeta REAC B A addmsg /kinetics/chain/kinetics[9]/PKC/PKM-zeta/diff /kinetics/chain/kinetics[9]/PKC/PKM-zeta REAC A B addmsg /kinetics/chain/kinetics[9]/PKC/PKM-zeta /kinetics/chain/kinetics[9]/PKC/PKM-zeta/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/PKC/PKM-zeta /kinetics/chain/kinetics[9]/PKC/PKM-zeta/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/PKC/PKC-act-by-DAG /kinetics/chain/kinetics[9]/DAG REAC A B addmsg /kinetics/chain/kinetics[9]/PKC/PKC-n-DAG /kinetics/chain/kinetics[9]/DAG REAC A B addmsg /kinetics/chain/kinetics[9]/PKC/PKC-Ca-memb* /kinetics/chain/kinetics[9]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[9]/PKC/PKC-DAG-memb* /kinetics/chain/kinetics[9]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[9]/PKC/PKM-zeta /kinetics/chain/kinetics[9]/PKC-active SUMTOTAL n nInit addmsg /kinetics/chain/kinetics[9]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[9]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[9]/PKC-active/PKC-inact-GAP /kinetics/chain/kinetics[9]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[9]/PKC-active/PKC-act-GEF /kinetics/chain/kinetics[9]/PKC-active REAC eA B addmsg /kinetics/chain/kinetics[9]/PKC-active /kinetics/chain/kinetics[9]/PKC-active/PKC-act-raf ENZYME n addmsg /kinetics/chain/kinetics[9]/MAPK/craf-1 /kinetics/chain/kinetics[9]/PKC-active/PKC-act-raf SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC-active /kinetics/chain/kinetics[9]/PKC-active/PKC-inact-GAP ENZYME n addmsg /kinetics/chain/kinetics[9]/Ras/GAP /kinetics/chain/kinetics[9]/PKC-active/PKC-inact-GAP SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/PKC-active /kinetics/chain/kinetics[9]/PKC-active/PKC-act-GEF ENZYME n addmsg /kinetics/chain/kinetics[9]/Ras/inact-GEF /kinetics/chain/kinetics[9]/PKC-active/PKC-act-GEF SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[9]/MAPK* REAC eA B addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[9]/MAPK* MM_PRD pA addmsg /kinetics/chain/kinetics[9]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[9]/MAPK* REAC sA B addmsg /kinetics/chain/kinetics[8]/MAPK*/diff /kinetics/chain/kinetics[9]/MAPK* REAC B A addmsg /kinetics/chain/kinetics[9]/MAPK*/diff /kinetics/chain/kinetics[9]/MAPK* REAC A B addmsg /kinetics/chain/kinetics[9]/MAPK* /kinetics/chain/kinetics[9]/MAPK*/MAPK*-feedback ENZYME n addmsg /kinetics/chain/kinetics[9]/MAPK/craf-1* /kinetics/chain/kinetics[9]/MAPK*/MAPK*-feedback SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK* /kinetics/chain/kinetics[9]/MAPK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/MAPK* /kinetics/chain/kinetics[9]/MAPK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[9]/MAPK/craf-1 REAC sA B addmsg /kinetics/chain/kinetics[9]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[9]/MAPK/craf-1 MM_PRD pA addmsg /kinetics/chain/kinetics[9]/Ras-act-unphosph-raf /kinetics/chain/kinetics[9]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1/diff /kinetics/chain/kinetics[9]/MAPK/craf-1 REAC B A addmsg /kinetics/chain/kinetics[9]/MAPK/craf-1/diff /kinetics/chain/kinetics[9]/MAPK/craf-1 REAC A B addmsg /kinetics/chain/kinetics[9]/MAPK/craf-1 /kinetics/chain/kinetics[9]/MAPK/craf-1/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/MAPK/craf-1 /kinetics/chain/kinetics[9]/MAPK/craf-1/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/PKC-active/PKC-act-raf /kinetics/chain/kinetics[9]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[9]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[9]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[9]/Ras-act-craf /kinetics/chain/kinetics[9]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[9]/PPhosphatase2A/craf-deph /kinetics/chain/kinetics[9]/MAPK/craf-1* REAC sA B addmsg /kinetics/chain/kinetics[9]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[9]/MAPK/craf-1* MM_PRD pA addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1*/diff /kinetics/chain/kinetics[9]/MAPK/craf-1* REAC B A addmsg /kinetics/chain/kinetics[9]/MAPK/craf-1*/diff /kinetics/chain/kinetics[9]/MAPK/craf-1* REAC A B addmsg /kinetics/chain/kinetics[9]/MAPK/craf-1* /kinetics/chain/kinetics[9]/MAPK/craf-1*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/MAPK/craf-1* /kinetics/chain/kinetics[9]/MAPK/craf-1*/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[9]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[9]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[9]/MAPK/MAPKK REAC sA B addmsg /kinetics/chain/kinetics[9]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[9]/MAPK/MAPKK MM_PRD pA addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK/diff /kinetics/chain/kinetics[9]/MAPK/MAPKK REAC B A addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK/diff /kinetics/chain/kinetics[9]/MAPK/MAPKK REAC A B addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK /kinetics/chain/kinetics[9]/MAPK/MAPKK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/MAPK/MAPKK /kinetics/chain/kinetics[9]/MAPK/MAPKK/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[9]/MAPK/MAPK REAC sA B addmsg /kinetics/chain/kinetics[9]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[9]/MAPK/MAPK MM_PRD pA addmsg /kinetics/chain/kinetics[8]/MAPK/MAPK/diff /kinetics/chain/kinetics[9]/MAPK/MAPK REAC B A addmsg /kinetics/chain/kinetics[9]/MAPK/MAPK/diff /kinetics/chain/kinetics[9]/MAPK/MAPK REAC A B addmsg /kinetics/chain/kinetics[9]/MAPK/MAPK /kinetics/chain/kinetics[9]/MAPK/MAPK/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/MAPK/MAPK /kinetics/chain/kinetics[9]/MAPK/MAPK/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/MAPK*/MAPK*-feedback /kinetics/chain/kinetics[9]/MAPK/craf-1** MM_PRD pA addmsg /kinetics/chain/kinetics[9]/PPhosphatase2A/craf**-deph /kinetics/chain/kinetics[9]/MAPK/craf-1** REAC sA B addmsg /kinetics/chain/kinetics[8]/MAPK/craf-1**/diff /kinetics/chain/kinetics[9]/MAPK/craf-1** REAC B A addmsg /kinetics/chain/kinetics[9]/MAPK/craf-1**/diff /kinetics/chain/kinetics[9]/MAPK/craf-1** REAC A B addmsg /kinetics/chain/kinetics[9]/MAPK/craf-1** /kinetics/chain/kinetics[9]/MAPK/craf-1**/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/MAPK/craf-1** /kinetics/chain/kinetics[9]/MAPK/craf-1**/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[9]/MKP-1/MKP1-tyr-deph /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr REAC sA B addmsg /kinetics/chain/kinetics[9]/MKP-1/MKP1-thr-deph /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr MM_PRD pA addmsg /kinetics/chain/kinetics[8]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr REAC B A addmsg /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr/diff /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr REAC A B addmsg /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/MAPK/MAPK-tyr /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK*/MAPKKtyr /kinetics/chain/kinetics[9]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK*/MAPKKthr /kinetics/chain/kinetics[9]/MAPK/MAPKK* REAC eA B addmsg /kinetics/chain/kinetics[9]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[9]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[9]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[9]/MAPK/MAPKK* MM_PRD pA addmsg /kinetics/chain/kinetics[9]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[9]/MAPK/MAPKK* REAC sA B addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[9]/MAPK/MAPKK* REAC B A addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK*/diff /kinetics/chain/kinetics[9]/MAPK/MAPKK* REAC A B addmsg /kinetics/chain/kinetics[9]/MAPK/MAPK /kinetics/chain/kinetics[9]/MAPK/MAPKK*/MAPKKtyr SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK* /kinetics/chain/kinetics[9]/MAPK/MAPKK*/MAPKKtyr ENZYME n addmsg /kinetics/chain/kinetics[9]/MAPK/MAPK-tyr /kinetics/chain/kinetics[9]/MAPK/MAPKK*/MAPKKthr SUBSTRATE n addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK* /kinetics/chain/kinetics[9]/MAPK/MAPKK*/MAPKKthr ENZYME n addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK* /kinetics/chain/kinetics[9]/MAPK/MAPKK*/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/MAPK/MAPKK* /kinetics/chain/kinetics[9]/MAPK/MAPKK*/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[9]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[9]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.1 /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[9]/MAPK/Raf*-GTP-Ras/Raf*-GTP-Ras.2 /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[9]/PPhosphatase2A/MAPKK-deph /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser MM_PRD pA addmsg /kinetics/chain/kinetics[9]/PPhosphatase2A/MAPKK-deph-ser /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser REAC sA B addmsg /kinetics/chain/kinetics[8]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser REAC B A addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser/diff /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser REAC A B addmsg /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser/diff SUBSTRATE n addmsg /kinetics/chain/kinetics[10]/MAPK/MAPKK-ser /kinetics/chain/kinetics[9]/MAPK/MAPKK-ser/diff PRODUCT n addmsg /kinetics/chain/kinetics[9]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.1 /kinetics/chain/kinetics[9]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[9]/MAPK/Raf-GTP-Ras/Raf-GTP-Ras.2 /kinetics/chain/kinetics[9]/MAPK/Raf-GTP-Ras REAC eA B addmsg /kinetics/chain/kinetics[9]/Ras-act-unphosph-raf /kinetics/chain/ki