NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Molecule Parameter List for CaM

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CaM participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000030

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
CaMKII33Network
Shared_Object_CaMKII CaM CaMKII 
CaN 
This is a deterministic, point kinetics approximation to the dendritic spine CaMKII model described in William R. Holmes J Comput Neurosci. (2000) 8(1):65-85. Rates are the same but the responses differ somewhat because this model does not include the stochastic and diffusive calculations of the original.

CaM acting as a Molecule in  
CaMKII Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
CaMCaMKII
Accession No. : 33
CaM
Pathway No. : 173
79.99970.1309No
Init conc form model is 80 uM.

CaM acting as a Substrate in a reaction in  
CaMKII Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
 NameAccession NamePathway NameKfKbKdtauReagents
1CaMKII-bind-CaMCaMKII
Accession No. : 33
CaMKII
Pathway No. : 174
0.2
(uM^-1 s^-1)
2700
(s^-1)
Kd(bf) = 13500(uM)-Substrate
CaM
CaMKII

Product
CaMKII-CaM
2CaM-bind-CaCaMKII
Accession No. : 33
CaM
Pathway No. : 173
1
(uM^-1 s^-1)
20
(s^-1)
Kd(bf) = 19.9992(uM)-Substrate
Ca
CaM

Product
CaMCa
3CaN-bind-CaMCaMKII
Accession No. : 33
CaN
Pathway No. : 175
0.2
(uM^-1 s^-1)
5000
(s^-1)
Kd(bf) = 25000(uM)-Substrate
CaM
CaN

Product
CaN-CaM



Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.