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Molecule Parameter List for CaMCa3

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CaMCa3 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000031

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
CaMKII33Network
Shared_Object_CaMKII CaM CaMKII 
CaN 
This is a deterministic, point kinetics approximation to the dendritic spine CaMKII model described in William R. Holmes J Comput Neurosci. (2000) 8(1):65-85. Rates are the same but the responses differ somewhat because this model does not include the stochastic and diffusive calculations of the original.

CaMCa3 acting as a Molecule in  
CaMKII Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
CaMCa3CaMKII
Accession No. : 33
CaM
Pathway No. : 173
00.1309No

CaMCa3 acting as a Substrate in a reaction in  
CaMKII Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
 NameAccession NamePathway NameKfKbKdtauReagents
1
  • CaMKII-bind-CaMC
    a3
  • CaMKII
    Accession No. : 33
    CaMKII
    Pathway No. : 174
    100.004
    (uM^-1 s^-1)
    22.5
    (s^-1)
    Kd(bf) = 0.225(uM)-Substrate
    CaMCa3
    CaMKII

    Product
    CaMKII-CaMCa3
    2CaMCa3-bind-CaCaMKII
    Accession No. : 33
    CaM
    Pathway No. : 173
    100.004
    (uM^-1 s^-1)
    500
    (s^-1)
    Kd(bf) = 4.9998(uM)-Substrate
    Ca
    CaMCa3

    Product
    CaMCa4
    3CaN-bind-CaMCa3CaMKII
    Accession No. : 33
    CaN
    Pathway No. : 175
    100.004
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaMCa3
    CaN

    Product
    CaN-CaMCa3

    CaMCa3 acting as a Product in a reaction in  
    CaMKII Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    CaMCa2-bind-CaCaMKII
    Accession No. : 33
    CaM
    Pathway No. : 173
    5
    (uM^-1 s^-1)
    500
    (s^-1)
    Kd(bf) = 99.9994(uM)-Substrate
    Ca
    CaMCa2

    Product
    CaMCa3



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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