NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Molecule Parameter List for AMP

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
AMP participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000400

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
fig3_CaMKII2Network
Shared_Object_fig3_CaMKII CaMKII CaM 
PP1 PP2B PKA 
AC 
This is the model file for figure 3 from Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It is a model of the Ca activation of CaMKII and other CaM-activated enzymes. It includes the regulatory phosphatases PP1 and PP2B (Calcineurin) acting on CaMKII and also includes CaM-activated adenylyl cyclase and PKA in the synapse.
Demonstration script files for generating the figures in the paper, including figure 3, are available here.

AMP acting as a Molecule in  
fig3_CaMKII Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
AMPfig3_CaMKII
Accession No. : 2
AC
Pathway No. : 18
3254900.0016667No

AMP acting as a Product of an Enzyme in  
fig3_CaMKII Network
 Enzyme Molecule /
Enzyme Activity
Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
1cAMP-PDE  /
PDE
fig3_CaMKII
Accession No. : 2
AC
Pathway No. : 18
19.8413104explicit E-S complexSubstrate
cAMP

Product
AMP
2cAMP-PDE*  /
PDE*
fig3_CaMKII
Accession No. : 2
AC
Pathway No. : 18
19.8413204explicit E-S complexSubstrate
cAMP

Product
AMP
3PDE1  /
PDE1
fig3_CaMKII
Accession No. : 2
AC
Pathway No. : 18
39.71.6674.0012explicit E-S complexSubstrate
cAMP

Product
AMP
4CaM.PDE1  /
CaM.PDE1
fig3_CaMKII
Accession No. : 2
AC
Pathway No. : 18
39.6825104explicit E-S complexSubstrate
cAMP

Product
AMP



Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.