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Molecule Parameter List for MAPK*

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
MAPK* participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1021100

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
fig4_synapse3Network
Shared_Object_fig4_synapse PKC PLA2 
PLCbeta Gq MAPK 
Ras CaMKII CaM 
PP1 PP2B PKA 
AC 
This is the composite model of 4 kinases: PKC, MAPK, PKA and CaMKII and numerous regulatory pathways involved in synaptic signaling. From Bhalla US and Iyengar R. Science (1999) 283(5400):381-7.This model comes from figure 4 of that paper.
Demonstration script files for generating the figures in the paper, including figure 4, are available here.

MAPK* acting as a Molecule in  
fig4_synapse Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
MAPK*fig4_synapse
Accession No. : 3
  • Shared_Object_
    fig4_synapse

    Pathway No. : 19
  • 01000No

    MAPK* acting as an Enzyme in  
    fig4_synapse Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1MAPK* /
    MAPK*
    fig4_synapse
    Accession No. : 3
  • Shared_Object_
    fig4_synapse

    Pathway No. : 19
  • 25.641204explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
    2MAPK* /
    MAPK*-feedback
    fig4_synapse
    Accession No. : 3
  • Shared_Object_
    fig4_synapse

    Pathway No. : 19
  • 25.641104explicit E-S complexSubstrate
    craf-1*

    Product
    craf-1**

    MAPK* acting as a Substrate for an Enzyme in  
    fig4_synapse Network
    Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    MKP-1  /
    MKP1-thr-deph
    fig4_synapse
    Accession No. : 3
  • Shared_Object_
    fig4_synapse

    Pathway No. : 19
  • 0.066666714explicit E-S complexSubstrate
    MAPK*

    Product
    MAPK-tyr

    MAPK* acting as a Product of an Enzyme in  
    fig4_synapse Network
    Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    MAPKK*  /
    MAPKKthr
    fig4_synapse
    Accession No. : 3
    MAPK
    Pathway No. : 24
    0.04629630.154explicit E-S complexSubstrate
    MAPK-tyr

    Product
    MAPK*



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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