NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Molecule Parameter List for A845*_B845*

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
A845*_B845* participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences2308621

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • AMPAR_traff_
    model1
  • 60Network
    Shared_Object_AMPAR_traff_model1 CaMKII CaM 
    PP1 PP2B PP1_PSD 
    PKA AC AMPAR 
    AMPAR_memb 
    This is the basic model of AMPAR trafficking bistability. It is based on Hayer and Bhalla, PLoS Comput. Biol. 2005. It includes the degradation and turnover of AMPARs. The CaMKII portion of the model is not bistable.

    A845*_B845* acting as a Molecule in  
    AMPAR_traff_model1 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    A845*_B845*
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    00.09No
    A845*_B845*
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR_memb
    Pathway No. : 253
    00.01No

    A845*_B845* acting as a Summed Molecule in  
    AMPAR_traff_model1 Network
     Accession NanePathway NameTargetInput
    1
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    I_845_PP
  • A835*845*_
    B835*845*

    A845*_B831*845*
    A831*845*_B845*
    A845*_B845*
  • 2
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR_memb
    Pathway No. : 253
    Ser845-PPA845*_B845*
    A831*845*_B845*
    A845*_B831*845*
  • A835*845*_
    B835*845*

  • 3
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR_memb
    Pathway No. : 253
    Ser831A845*_B845*
    A_B845*
    A845*_B
    A_B

    A845*_B845* acting as a Substrate for an Enzyme in  
    AMPAR_traff_model1 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1actCaMKII-PSD  /
    CaMKII
  • AMPAR_traff_
    model1

    Accession No. : 60
  • CaMKII
    Pathway No. : 245
    90.00060.54explicit E-S complexSubstrate
    A845*_B845*

    Product
    A831*845*_B845*
    2actCaMKII-PSD  /
    CaMKII[4]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • CaMKII
    Pathway No. : 245
    90.00060.54explicit E-S complexSubstrate
    A845*_B845*

    Product
    A845*_B831*845*
    3CaM_Ca_n-CaNAB  /
    PP2B[25]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP2B
    Pathway No. : 248
    4.9706124explicit E-S complexSubstrate
    A845*_B845*

    Product
    A_B845*
    4CaM_Ca_n-CaNAB  /
    PP2B[29]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP2B
    Pathway No. : 248
    4.9706124explicit E-S complexSubstrate
    A845*_B845*

    Product
    A845*_B
    5CaM_Ca_n-CaNAB  /
    PP2B
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP2B
    Pathway No. : 248
    4.9706124explicit E-S complexSubstrate
    A845*_B845*

    Product
    A_B845*
    6CaM_Ca_n-CaNAB  /
    PP2B[1]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP2B
    Pathway No. : 248
    4.9706124explicit E-S complexSubstrate
    A845*_B845*

    Product
    A845*_B
    7PP1-active_PSD  /
    PP1
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP1_PSD
    Pathway No. : 249
    0.9714510.174explicit E-S complexSubstrate
    A845*_B845*

    Product
    A_B845*
    8PP1-active_PSD  /
    PP1[1]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP1_PSD
    Pathway No. : 249
    0.9714510.174explicit E-S complexSubstrate
    A845*_B845*

    Product
    A845*_B

    A845*_B845* acting as a Product of an Enzyme in  
    AMPAR_traff_model1 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1PKA-active  /
    PKA[24]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PKA
    Pathway No. : 250
    7.5002164explicit E-S complexSubstrate
    A_B845*

    Product
    A845*_B845*
    2PKA-active  /
    PKA[28]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PKA
    Pathway No. : 250
    7.5002164explicit E-S complexSubstrate
    A845*_B

    Product
    A845*_B845*
    3PKA-active  /
    PKA
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PKA
    Pathway No. : 250
    7.5002164explicit E-S complexSubstrate
    A_B845*

    Product
    A845*_B845*
    4PKA-active  /
    PKA[1]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PKA
    Pathway No. : 250
    7.5002164explicit E-S complexSubstrate
    A845*_B

    Product
    A845*_B845*
    5PP1-active_PSD  /
    PP1[8]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP1_PSD
    Pathway No. : 249
    2.000050.354explicit E-S complexSubstrate
    A831*845*_B845*

    Product
    A845*_B845*
    6PP1-active_PSD  /
    PP1[21]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP1_PSD
    Pathway No. : 249
    2.000050.354explicit E-S complexSubstrate
    A845*_B831*845*

    Product
    A845*_B845*

    A845*_B845* acting as a Substrate in a reaction in  
    AMPAR_traff_model1 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1degrade__
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0
    (s^-1)
    0
    (s^-1)
    --Substrate
    A845*_B845*

    Product
    AMPAR_deg
    2exo_reg__
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0.0002
    (#^-1 s^-1)
    0.008
    (s^-1)
    Not applicable**-Substrate
    A845*_B845*
    Anchor

    Product
    A845*_B845*
      Exo rates are scaled from earlier model versions to account for binding of anchor. We have about 200 molecules of anchor in the whole model. Here we select rates to give us a max of about 150 molecules of GluR at the synapse.
    ** This is a trasport reation between compartments of different volumes. Therefore Kd is not applicable. Please Note Kf, Kb units are in number of molecules instead of concentration

    A845*_B845* acting as a Product in a reaction in  
    AMPAR_traff_model1 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    exo_reg__
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0.0002
    (#^-1 s^-1)
    0.008
    (s^-1)
    Not applicable**-Substrate
    A845*_B845*
    Anchor

    Product
    A845*_B845*
    Exo rates are scaled from earlier model versions to account for binding of anchor. We have about 200 molecules of anchor in the whole model. Here we select rates to give us a max of about 150 molecules of GluR at the synapse.
    ** This is a trasport reation between compartments of different volumes. Therefore Kd is not applicable. Please Note Kf, Kb units are in number of molecules instead of concentration



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.