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Molecule Parameter List for A835*845*_B835*845*

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
A835*845*_B835*845* participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences2308621

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • AMPAR_traff_
    model1
  • 60Network
    Shared_Object_AMPAR_traff_model1 CaMKII CaM 
    PP1 PP2B PP1_PSD 
    PKA AC AMPAR 
    AMPAR_memb 
    This is the basic model of AMPAR trafficking bistability. It is based on Hayer and Bhalla, PLoS Comput. Biol. 2005. It includes the degradation and turnover of AMPARs. The CaMKII portion of the model is not bistable.

    A835*845*_B835*845* acting as a Molecule in  
    AMPAR_traff_model1 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    A835*845*_B835*845*
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    00.09No
    A835*845*_B835*845*
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR_memb
    Pathway No. : 253
    00.01No

    A835*845*_B835*845* acting as a Summed Molecule in  
    AMPAR_traff_model1 Network
     Accession NanePathway NameTargetInput
    1
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    I_845_PP
  • A835*845*_
    B835*845*

    A845*_B831*845*
    A831*845*_B845*
    A845*_B845*
  • 2
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR_memb
    Pathway No. : 253
    Ser845-PPA845*_B845*
    A831*845*_B845*
    A845*_B831*845*
  • A835*845*_
    B835*845*

  • 3
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR_memb
    Pathway No. : 253
    Ser831-PP
  • A835*845*_
    B835*845*

    A831*_B831*845*
    A831*845*_B831*
    A831*_B831*

  • A835*845*_B835*845* acting as a Substrate for an Enzyme in  
    AMPAR_traff_model1 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1CaM_Ca_n-CaNAB  /
    PP2B[28]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP2B
    Pathway No. : 248
    4.9706124explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*_B831*845*
  • 2CaM_Ca_n-CaNAB  /
    PP2B[32]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP2B
    Pathway No. : 248
    4.9706124explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*845*_B831*
  • 3CaM_Ca_n-CaNAB  /
    PP2B[12]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP2B
    Pathway No. : 248
    4.9706124explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*_B831*845*
  • 4CaM_Ca_n-CaNAB  /
    PP2B[13]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP2B
    Pathway No. : 248
    4.9706124explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*845*_B831*
  • 5PP1-active_PSD  /
    PP1[16]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP1_PSD
    Pathway No. : 249
    0.9714510.174explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*_B831*845*
  • 6PP1-active_PSD  /
    PP1[17]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP1_PSD
    Pathway No. : 249
    0.9714510.174explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*845*_B831*
  • 7PP1-active_PSD  /
    PP1[24]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP1_PSD
    Pathway No. : 249
    2.000050.354explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A845*_B831*845*
  • 8PP1-active_PSD  /
    PP1[28]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PP1_PSD
    Pathway No. : 249
    2.000050.354explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*845*_B845*

  • A835*845*_B835*845* acting as a Product of an Enzyme in  
    AMPAR_traff_model1 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1actCaMKII-PSD  /
    CaMKII[8]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • CaMKII
    Pathway No. : 245
    90.00060.54explicit E-S complexSubstrate
    A845*_B831*845*

    Product
  • A835*845*_
    B835*845*

  • 2actCaMKII-PSD  /
    CaMKII[12]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • CaMKII
    Pathway No. : 245
    90.00060.54explicit E-S complexSubstrate
    A831*845*_B845*

    Product
  • A835*845*_
    B835*845*

  • 3PKA-active  /
    PKA[27]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PKA
    Pathway No. : 250
    7.5002164explicit E-S complexSubstrate
    A831*_B831*845*

    Product
  • A835*845*_
    B835*845*

  • 4PKA-active  /
    PKA[31]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PKA
    Pathway No. : 250
    7.5002164explicit E-S complexSubstrate
    A831*845*_B831*

    Product
  • A835*845*_
    B835*845*

  • 5PKA-active  /
    PKA[12]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PKA
    Pathway No. : 250
    7.5002164explicit E-S complexSubstrate
    A831*_B831*845*

    Product
  • A835*845*_
    B835*845*

  • 6PKA-active  /
    PKA[13]
  • AMPAR_traff_
    model1

    Accession No. : 60
  • PKA
    Pathway No. : 250
    7.5002164explicit E-S complexSubstrate
    A831*845*_B831*

    Product
  • A835*845*_
    B835*845*


  • A835*845*_B835*845* acting as a Substrate in a reaction in  
    AMPAR_traff_model1 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1degrade**
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0
    (s^-1)
    0
    (s^-1)
    --Substrate
  • A835*845*_
    B835*845*


    Product
    AMPAR_deg
  • 2exo_reg**
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0.0002
    (#^-1 s^-1)
    0.008
    (s^-1)
    Not applicable**-Substrate
  • A835*845*_
    B835*845*

    Anchor

    Product
  • A835*845*_
    B835*845*

  • ** This is a trasport reation between compartments of different volumes. Therefore Kd is not applicable. Please Note Kf, Kb units are in number of molecules instead of concentration

    A835*845*_B835*845* acting as a Product in a reaction in  
    AMPAR_traff_model1 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    exo_reg**
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0.0002
    (#^-1 s^-1)
    0.008
    (s^-1)
    Not applicable**-Substrate
  • A835*845*_
    B835*845*

    Anchor

    Product
  • A835*845*_
    B835*845*

  • ** This is a trasport reation between compartments of different volumes. Therefore Kd is not applicable. Please Note Kf, Kb units are in number of molecules instead of concentration



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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