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Molecule Parameter List for A835*845*_B835*845*

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
A835*845*_B835*845* participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences2308621

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • AMPAR_CaMKII_
    weak_coupling
  • 65Network
    Shared_Object_AMPAR_CaMKII_weak_coupling CaMKII CaM 
    PP1 PP2B PP1_PSD 
    AMPAR PKA AC 
    AMPAR_memb PP1_CaMKII_PSD CaMKII_PSD 
    This is a model of weak coupling between the AMPAR traffikcing bistability, and the CaMKII autophosphorylation bistability. In this model, there are three stable states: Both off, AMPAR on, or both on. The fourth possible state: CaMKII on but AMPAR off, is not truly stable, since over the course of hours the AMPAR also turns on.

    A835*845*_B835*845* acting as a Molecule in  
    AMPAR_CaMKII_weak_coupling Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    A835*845*_B835*845*
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • AMPAR
    Pathway No. : 287
    00.09No
    A835*845*_B835*845*
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • AMPAR_memb
    Pathway No. : 290
    00.01No

    A835*845*_B835*845* acting as a Summed Molecule in  
    AMPAR_CaMKII_weak_coupling Network
     Accession NanePathway NameTargetInput
    1
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • Shared_Object_
    AMPAR_CaMKII_
    weak_coupling

    Pathway No. : 281
  • Ser845-PPA845*_B845*
    A831*845*_B845*
    A845*_B831*845*
  • A835*845*_
    B835*845*

  • 2
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • Shared_Object_
    AMPAR_CaMKII_
    weak_coupling

    Pathway No. : 281
  • Ser831-PP
  • A835*845*_
    B835*845*

    A831*_B831*845*
    A831*845*_B831*
    A831*_B831*
  • 3
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • Shared_Object_
    AMPAR_CaMKII_
    weak_coupling

    Pathway No. : 281
  • I_845_PP
  • A835*845*_
    B835*845*

    A845*_B831*845*
    A831*845*_B845*
    A845*_B845*

  • A835*845*_B835*845* acting as a Substrate for an Enzyme in  
    AMPAR_CaMKII_weak_coupling Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1CaM_Ca_n-CaNAB  /
    PP2B[28]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • PP2B
    Pathway No. : 285
    4.9706124explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*_B831*845*
  • 2CaM_Ca_n-CaNAB  /
    PP2B[32]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • PP2B
    Pathway No. : 285
    4.9706124explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*845*_B831*
  • 3CaM_Ca_n-CaNAB  /
    PP2B[12]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • PP2B
    Pathway No. : 285
    4.9706124explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*_B831*845*
  • 4CaM_Ca_n-CaNAB  /
    PP2B[13]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • PP2B
    Pathway No. : 285
    4.9706124explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*845*_B831*
  • 5PP1-active_PSD  /
    PP1[16]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • PP1_PSD
    Pathway No. : 286
    0.9714510.174explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*_B831*845*
  • 6PP1-active_PSD  /
    PP1[17]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • PP1_PSD
    Pathway No. : 286
    0.9714510.174explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*845*_B831*
  • 7PP1-active_PSD  /
    PP1[24]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • PP1_PSD
    Pathway No. : 286
    2.000050.354explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A845*_B831*845*
  • 8PP1-active_PSD  /
    PP1[28]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • PP1_PSD
    Pathway No. : 286
    2.000050.354explicit E-S complexSubstrate
  • A835*845*_
    B835*845*


    Product
    A831*845*_B845*

  • A835*845*_B835*845* acting as a Product of an Enzyme in  
    AMPAR_CaMKII_weak_coupling Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1PKA-active  /
    PKA[27]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • PKA
    Pathway No. : 288
    7.5002164explicit E-S complexSubstrate
    A831*_B831*845*

    Product
  • A835*845*_
    B835*845*

  • 2PKA-active  /
    PKA[31]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • PKA
    Pathway No. : 288
    7.5002164explicit E-S complexSubstrate
    A831*845*_B831*

    Product
  • A835*845*_
    B835*845*

  • 3PKA-active  /
    PKA[12]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • PKA
    Pathway No. : 288
    7.5002164explicit E-S complexSubstrate
    A831*_B831*845*

    Product
  • A835*845*_
    B835*845*

  • 4PKA-active  /
    PKA[13]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • PKA
    Pathway No. : 288
    7.5002164explicit E-S complexSubstrate
    A831*845*_B831*

    Product
  • A835*845*_
    B835*845*

  • 5actCaMKII-PSD  /
    CaMKII[8]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • CaMKII_PSD
    Pathway No. : 292
    90.00060.54explicit E-S complexSubstrate
    A845*_B831*845*

    Product
  • A835*845*_
    B835*845*

  • 6actCaMKII-PSD  /
    CaMKII[12]
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • CaMKII_PSD
    Pathway No. : 292
    90.00060.54explicit E-S complexSubstrate
    A831*845*_B845*

    Product
  • A835*845*_
    B835*845*


  • A835*845*_B835*845* acting as a Substrate in a reaction in  
    AMPAR_CaMKII_weak_coupling Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1degrade**
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • AMPAR
    Pathway No. : 287
    0
    (s^-1)
    0
    (s^-1)
    --Substrate
  • A835*845*_
    B835*845*


    Product
    AMPAR_deg
  • 2exo_reg**
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • AMPAR
    Pathway No. : 287
    0.0002
    (#^-1 s^-1)
    0.008
    (s^-1)
    Not applicable**-Substrate
  • A835*845*_
    B835*845*

    Anchor

    Product
  • A835*845*_
    B835*845*

  • ** This is a trasport reation between compartments of different volumes. Therefore Kd is not applicable. Please Note Kf, Kb units are in number of molecules instead of concentration

    A835*845*_B835*845* acting as a Product in a reaction in  
    AMPAR_CaMKII_weak_coupling Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    exo_reg**
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • AMPAR
    Pathway No. : 287
    0.0002
    (#^-1 s^-1)
    0.008
    (s^-1)
    Not applicable**-Substrate
  • A835*845*_
    B835*845*

    Anchor

    Product
  • A835*845*_
    B835*845*

  • ** This is a trasport reation between compartments of different volumes. Therefore Kd is not applicable. Please Note Kf, Kb units are in number of molecules instead of concentration



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