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Molecule Parameter List for tot_autonomous_CaMKII

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
tot_autonomous_CaMKII participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1220000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
fig4_synapse3Network
Shared_Object_fig4_synapse PKC PLA2 
PLCbeta Gq MAPK 
Ras CaMKII CaM 
PP1 PP2B PKA 
AC 
This is the composite model of 4 kinases: PKC, MAPK, PKA and CaMKII and numerous regulatory pathways involved in synaptic signaling. From Bhalla US and Iyengar R. Science (1999) 283(5400):381-7.This model comes from figure 4 of that paper.
Demonstration script files for generating the figures in the paper, including figure 4, are available here.

tot_autonomous_CaMKII acting as a Molecule in  
fig4_synapse Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
tot_autonomous_CaMKIIfig4_synapse
Accession No. : 3
CaMKII
Pathway No. : 26
01000No

tot_autonomous_CaMKII acting as a Summed Molecule in  
fig4_synapse Network
 Accession NanePathway NameTargetInput
1fig4_synapse
Accession No. : 3
CaMKII
Pathway No. : 26
tot_autonomous_CaMKIICaMKII-thr286
CaMKII***
2fig4_synapse
Accession No. : 3
  • Shared_Object_
    fig4_synapse

    Pathway No. : 19
  • CaMKII-acttot_CaM_CaMKII
  • tot_autonomous_
    CaMKII


  • tot_autonomous_CaMKII acting as an Enzyme in  
    fig4_synapse Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1
  • tot_autonomous_
    CaMKII
     /
    auton_305
  • fig4_synapse
    Accession No. : 3
    CaMKII
    Pathway No. : 26
    0.0000041666764explicit E-S complexSubstrate
    CaMKII-thr286

    Product
    CaMKII***
    2
  • tot_autonomous_
    CaMKII
     /
    auton_286
  • fig4_synapse
    Accession No. : 3
    CaMKII
    Pathway No. : 26
    0.000004166670.54explicit E-S complexSubstrate
    CaMKII-CaM

    Product
  • CaMKII-thr286*-C
    aM




  • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.