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Molecule Parameter List for tot_CaM_CaMKII

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
tot_CaM_CaMKII participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1120000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Ajay_Bhalla_
    2004_Feedback_
    Tuning
  • 78Network
    Shared_Object_Ajay_Bhalla_2004_Feedback_Tuning PKC PLA2 
    PLCbeta Gq MAPK 
    Ras EGFR Sos 
    PLC_g CaMKII CaM 
    PP1 PP2B PKA 
    AC 
    This model is taken from Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. This is the feedback model from Figure 8a.

    tot_CaM_CaMKII acting as a Molecule in  
    Ajay_Bhalla_2004_Feedback_Tuning Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    tot_CaM_CaMKII
  • Ajay_Bhalla_
    2004_Feedback_
    Tuning

    Accession No. : 78
  • CaMKII
    Pathway No. : 357
    01.5No

    tot_CaM_CaMKII acting as a Summed Molecule in  
    Ajay_Bhalla_2004_Feedback_Tuning Network
    Accession NamePathway NameTargetInput
  • Ajay_Bhalla_
    2004_Feedback_
    Tuning

    Accession No. : 78
  • CaMKII
    Pathway No. : 357
    tot_CaM_CaMKIICaMKII-CaM
  • CaMKII-thr286*-C
    aM


  • tot_CaM_CaMKII acting as an Enzyme in  
    Ajay_Bhalla_2004_Feedback_Tuning Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1tot_CaM_CaMKII /
    CaM_act_305
  • Ajay_Bhalla_
    2004_Feedback_
    Tuning

    Accession No. : 78
  • CaMKII
    Pathway No. : 357
    113.59964explicit E-S complexSubstrate
    CaMKII-thr286

    Product
    CaMKII***
        Rates from autocamtide phosphorylation, from Hanson and Schulman JBC 267:24 17216-17224 1992. Jan 1 1998: Speed up 12x to match fig 5.
    2tot_CaM_CaMKII /
    CaM_act_286
  • Ajay_Bhalla_
    2004_Feedback_
    Tuning

    Accession No. : 78
  • CaMKII
    Pathway No. : 357
    113.6010.54explicit E-S complexSubstrate
    CaMKII-CaM

    Product
  • CaMKII-thr286*-C
    aM

  •    



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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