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Molecule Parameter List for craf-1**

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

craf-1** participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	25	0	0	25	25	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Ajay_bhalla_ 2007_ReacDiff1_ 1e-12	81	Network	Shared_Object_Ajay_bhalla_2007_ReacDiff1_1e-12, PKC, MAPK, Ras, CaM, PKM, chain, kinetics, PKC, MAPK, Ras, CaM, PKM, kinetics[1], PKC, MAPK, Ras, CaM, PKM, kinetics[2], PKC, MAPK, Ras, CaM, PKM, kinetics[3], PKC, MAPK, MAPK, Ras, CaM, PKM, kinetics[4], PKC, MAPK, Ras, CaM, PKM, kinetics[5], PKC, MAPK, Ras, kinetics[6], CaM, PKM, PKC, MAPK, Ras, CaM, PKM, kinetics[7], PKC, Ras, CaM, PKM, kinetics[8], PKC, MAPK, Ras, CaM, PKM, kinetics[9], PKC, MAPK, Ras, CaM, PKM, kinetics[10], PKC, MAPK, Ras, CaM, PKM, kinetics[11], PKC, MAPK, Ras, CaM, PKM, kinetics[12], PKC, MAPK, Ras, CaM, PKM, kinetics[13], PKC, MAPK, Ras, CaM, PKM, kinetics[14], PKC, MAPK, Ras, CaM, PKM, kinetics[15], PKC, MAPK, Ras, CaM, PKM, kinetics[16], PKC, MAPK, Ras, CaM, PKM, kinetics[17], PKC, MAPK, Ras, CaM, PKM, kinetics[18], PKC, MAPK, Ras, CaM, PKM, kinetics[19], PKC, MAPK, Ras, CaM, PKM, kinetics[20], PKC, MAPK, Ras, CaM, PKM, kinetics[21], PKC, MAPK, Ras, CaM, PKM, kinetics[22], PKC, MAPK, Ras, CaM, PKM, kinetics[23], PKC, MAPK, Ras, CaM, PKM
This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec. The stimulus file pkm_mapk22_diff_1e-12_Fig4A which was used for the model to replicate Figure 4A from the paper. This stimulus file pkm_mapk22_diff_1e-12_Fig4G which was used for the model to replicate Figure 4G from the paper

craf-1** acting as a Molecule in Ajay_bhalla_2007_ReacDiff1_1e-12 Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 377	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 384	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 390	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 396	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 403	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 409	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 415	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 421	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 402	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 432	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 438	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 444	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 450	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 456	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 462	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 468	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 474	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 480	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 486	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 492	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 498	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 504	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 510	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 516	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*
craf-1**	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	MAPK Pathway No. : 522	0	1.5	No
Negative feedback by MAPK by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994*

craf-1** acting as a Substrate for an Enzyme in Ajay_bhalla_2007_ReacDiff1_1e-12 Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
2	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics Pathway No. : 382	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
3	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[1] Pathway No. : 388	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
4	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[2] Pathway No. : 394	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
5	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[3] Pathway No. : 400	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
6	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[4] Pathway No. : 407	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
7	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[5] Pathway No. : 413	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
8	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[6] Pathway No. : 417	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
9	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[7] Pathway No. : 425	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
10	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[8] Pathway No. : 430	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
11	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[9] Pathway No. : 436	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
12	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[10] Pathway No. : 442	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
13	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[11] Pathway No. : 448	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
14	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[12] Pathway No. : 454	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
15	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[13] Pathway No. : 460	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
16	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[14] Pathway No. : 466	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
17	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[15] Pathway No. : 472	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
18	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[16] Pathway No. : 478	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
19	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[17] Pathway No. : 484	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
20	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[18] Pathway No. : 490	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
21	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[19] Pathway No. : 496	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
22	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[20] Pathway No. : 502	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
23	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[21] Pathway No. : 508	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
24	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[22] Pathway No. : 514	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.
25	PPhosphatase2A / craf**-deph	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[23] Pathway No. : 520	15.6567	6	4	explicit E-S complex	Substrate craf-1 Product** craf-1*
	Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so.

craf-1** acting as a Product of an Enzyme in Ajay_bhalla_2007_ReacDiff1_1e-12 Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
2	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics Pathway No. : 382	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
3	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[1] Pathway No. : 388	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
4	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[2] Pathway No. : 394	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
5	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[3] Pathway No. : 400	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
6	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[4] Pathway No. : 407	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
7	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[5] Pathway No. : 413	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
8	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[6] Pathway No. : 417	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
9	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[7] Pathway No. : 425	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
10	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[8] Pathway No. : 430	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
11	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[9] Pathway No. : 436	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
12	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[10] Pathway No. : 442	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
13	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[11] Pathway No. : 448	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
14	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[12] Pathway No. : 454	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
15	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[13] Pathway No. : 460	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
16	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[14] Pathway No. : 466	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
17	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[15] Pathway No. : 472	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
18	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[16] Pathway No. : 478	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
19	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[17] Pathway No. : 484	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
20	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[18] Pathway No. : 490	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
21	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[19] Pathway No. : 496	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
22	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[20] Pathway No. : 502	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
23	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[21] Pathway No. : 508	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
24	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[22] Pathway No. : 514	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*
25	MAPK* / MAPK*-feedback	Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81	kinetics[23] Pathway No. : 520	25.6405	10	4	explicit E-S complex	Substrate craf-1* Product craf-1**
	Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK notes.*

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