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Molecule Parameter List for CaM-Ca4

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CaM-Ca4 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences2500007449

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12
  • 81NetworkShared_Object_Ajay_bhalla_2007_ReacDiff1_1e-12 
    PKC MAPK Ras CaM PKM chain kinetics PKC MAPK Ras CaM PKM kinetics[1] 
    PKC MAPK Ras CaM PKM kinetics[2] PKC MAPK Ras CaM PKM kinetics[3] 
    PKC MAPK MAPK Ras CaM PKM kinetics[4] PKC MAPK Ras CaM PKM 
    kinetics[5] PKC MAPK Ras kinetics[6] CaM PKM PKC MAPK Ras 
    CaM PKM kinetics[7] PKC Ras CaM PKM kinetics[8] PKC MAPK 
    Ras CaM PKM kinetics[9] PKC MAPK Ras CaM PKM kinetics[10] 
    PKC MAPK Ras CaM PKM kinetics[11] PKC MAPK Ras CaM PKM kinetics[12] 
    PKC MAPK Ras CaM PKM kinetics[13] PKC MAPK Ras CaM PKM kinetics[14] 
    PKC MAPK Ras CaM PKM kinetics[15] PKC MAPK Ras CaM PKM kinetics[16] 
    PKC MAPK Ras CaM PKM kinetics[17] PKC MAPK Ras CaM PKM kinetics[18] 
    PKC MAPK Ras CaM PKM kinetics[19] PKC MAPK Ras CaM PKM kinetics[20] 
    PKC MAPK Ras CaM PKM kinetics[21] PKC MAPK Ras CaM PKM kinetics[22] 
    PKC MAPK Ras CaM PKM kinetics[23] PKC MAPK Ras CaM PKM 
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
    The stimulus file pkm_mapk22_diff_1e-12_Fig4A which was used for the model to replicate Figure 4A from the paper.
    This stimulus file pkm_mapk22_diff_1e-12_Fig4G which was used for the model to replicate Figure 4G from the paper

    CaM-Ca4 acting as a Molecule in  
    Ajay_bhalla_2007_ReacDiff1_1e-12 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 379
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 386
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 392
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 398
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 405
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 411
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 418
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 423
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 428
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 434
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 440
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 446
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 452
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 458
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 464
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 470
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 476
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 482
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 488
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 494
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 500
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 506
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 512
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 518
    01.5No
    CaM-Ca4
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 524
    01.5No

    CaM-Ca4 acting as a Substrate in a reaction in  
    Ajay_bhalla_2007_ReacDiff1_1e-12 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 378
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    2diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    3trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 380
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 4CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 385
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    5diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    6trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 387
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 7CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 391
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    8diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    9trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 393
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 10CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 397
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    11diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    12trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 399
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 13CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 404
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    14diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    15trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 406
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 16CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 410
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    17diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    18trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 412
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 19CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 416
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    20diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    21trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 419
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 22CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 422
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    23diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    24trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 424
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 25CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 427
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    26diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    27trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 429
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 28CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 433
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    29diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    30trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 435
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 31CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 439
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    32diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    33trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 441
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 34CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 445
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    35diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    36trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 447
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 37CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 451
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    38diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    39trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 453
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 40CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 457
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    41diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    42trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 459
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 43CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 463
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    44diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    45trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 465
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 46CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 469
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    47diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    48trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 471
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 49CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 475
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    50diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    51trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 477
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 52CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 481
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    53diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    54trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 483
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 55CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 487
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    56diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    57trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 489
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 58CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 493
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    59diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    60trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 495
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 61CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 499
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    62diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    63trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 501
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 64CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 505
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    65diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    66trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 507
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 67CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 511
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    68diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    69trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 513
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 70CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 517
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    71diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    72trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 519
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex

  • 73CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 523
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    74trigger_PKM
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • PKM
    Pathway No. : 525
    9.9998
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    CaM-Ca4
    Ca_detector

    Product
  • Ca.detector_
    complex


  • CaM-Ca4 acting as a Product in a reaction in  
    Ajay_bhalla_2007_ReacDiff1_1e-12 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 379
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    2diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    3CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 386
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    4diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    5CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 392
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    6diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    7CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 398
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    8diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    9CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 405
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    10diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    11CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 411
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    12diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    13CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 418
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    14diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    15CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 423
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    16diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    17CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 428
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    18diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    19CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 434
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    20diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    21CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 440
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    22diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    23CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 446
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    24diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    25CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 452
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    26diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    27CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 458
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    28diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    29CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 464
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    30diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    31CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 470
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    32diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    33CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 476
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    34diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    35CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 482
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    36diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    37CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 488
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    38diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    39CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 494
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    40diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    41CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 500
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    42diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    43CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 506
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    44diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    45CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 512
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    46diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    47CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 518
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10
    48diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-Ca4

    Product
    CaM-Ca4
    49CaM-Ca3-bind-Ca
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • CaM
    Pathway No. : 524
    0.465
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 21.5051(uM)-Substrate
    Ca
    CaM-Ca3

    Product
    CaM-Ca4
      Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10



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