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Molecule Parameter List for CaM-GEF

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CaM-GEF participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences25025002449

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12
  • 81NetworkShared_Object_Ajay_bhalla_2007_ReacDiff1_1e-12 
    PKC MAPK Ras CaM PKM chain kinetics PKC MAPK Ras CaM PKM kinetics[1] 
    PKC MAPK Ras CaM PKM kinetics[2] PKC MAPK Ras CaM PKM kinetics[3] 
    PKC MAPK MAPK Ras CaM PKM kinetics[4] PKC MAPK Ras CaM PKM 
    kinetics[5] PKC MAPK Ras kinetics[6] CaM PKM PKC MAPK Ras 
    CaM PKM kinetics[7] PKC Ras CaM PKM kinetics[8] PKC MAPK 
    Ras CaM PKM kinetics[9] PKC MAPK Ras CaM PKM kinetics[10] 
    PKC MAPK Ras CaM PKM kinetics[11] PKC MAPK Ras CaM PKM kinetics[12] 
    PKC MAPK Ras CaM PKM kinetics[13] PKC MAPK Ras CaM PKM kinetics[14] 
    PKC MAPK Ras CaM PKM kinetics[15] PKC MAPK Ras CaM PKM kinetics[16] 
    PKC MAPK Ras CaM PKM kinetics[17] PKC MAPK Ras CaM PKM kinetics[18] 
    PKC MAPK Ras CaM PKM kinetics[19] PKC MAPK Ras CaM PKM kinetics[20] 
    PKC MAPK Ras CaM PKM kinetics[21] PKC MAPK Ras CaM PKM kinetics[22] 
    PKC MAPK Ras CaM PKM kinetics[23] PKC MAPK Ras CaM PKM 
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
    The stimulus file pkm_mapk22_diff_1e-12_Fig4A which was used for the model to replicate Figure 4A from the paper.
    This stimulus file pkm_mapk22_diff_1e-12_Fig4G which was used for the model to replicate Figure 4G from the paper

    CaM-GEF acting as a Molecule in  
    Ajay_bhalla_2007_ReacDiff1_1e-12 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 378
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 385
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 391
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 397
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 404
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 410
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 416
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 422
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 427
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 433
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 439
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 445
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 451
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 457
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 463
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 469
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 475
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 481
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 487
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 493
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 499
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 505
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 511
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 517
    01.5No
    See Farnsworth et al Nature 376 524-527 1995
    CaM-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 523
    01.5No
    See Farnsworth et al Nature 376 524-527 1995

    CaM-GEF acting as an Enzyme in  
    Ajay_bhalla_2007_ReacDiff1_1e-12 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 378
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    2CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 385
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    3CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 391
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    4CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 397
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    5CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 404
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    6CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 410
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    7CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 416
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    8CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 422
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    9CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 427
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    10CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 433
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    11CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 439
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    12CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 445
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    13CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 451
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    14CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 457
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    15CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 463
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    16CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 469
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    17CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 475
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    18CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 481
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    19CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 487
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    20CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 493
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    21CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 499
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    22CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 505
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    23CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 511
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    24CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 517
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
    25CaM-GEF /
    CaM-GEF-act-ras
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 523
    0.5050570.24explicit E-S complexSubstrate
    GDP-Ras

    Product
    GTP-Ras
        Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.

    CaM-GEF acting as a Substrate in a reaction in  
    Ajay_bhalla_2007_ReacDiff1_1e-12 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    2diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    3diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    4diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    5diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    6diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    7diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    8diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    9diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    10diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    11diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    12diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    13diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    14diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    15diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    16diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    17diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    18diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    19diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    20diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    21diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    22diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    23diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    24diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF

    CaM-GEF acting as a Product in a reaction in  
    Ajay_bhalla_2007_ReacDiff1_1e-12 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 378
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    2diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    3CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 385
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    4diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    5CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 391
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    6diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    7CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 397
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    8diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    9CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 404
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    10diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    11CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 410
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    12diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    13CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 416
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    14diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    15CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 422
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    16diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    17CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 427
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    18diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    19CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 433
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    20diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    21CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 439
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    22diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    23CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 445
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    24diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    25CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 451
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    26diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    27CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 457
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    28diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    29CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 463
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    30diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    31CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 469
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    32diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    33CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 475
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    34diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    35CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 481
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    36diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    37CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 487
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    38diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    39CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 493
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    40diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    41CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 499
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    42diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    43CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 505
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    44diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    45CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 511
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    46diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    47CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 517
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
    48diff
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Shared_Object_
    Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Pathway No. : 375
  • 0.01
    (s^-1)
    0.01
    (s^-1)
    Keq = 1(uM)50secSubstrate
    CaM-GEF

    Product
    CaM-GEF
    49CaM-bind-GEF
  • Ajay_bhalla_
    2007_ReacDiff1_
    1e-12

    Accession No. : 81
  • Ras
    Pathway No. : 523
    199.995
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.005(uM)-Substrate
    CaM-Ca4
    inact-GEF

    Product
    CaM-GEF
      We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995



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