NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Molecule Parameter List for DAG-Ca-PLA2*

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
DAG-Ca-PLA2* participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1010001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
3d_fold_model8Network
Shared_Object_3d_fold_model PKC MAPK 
PLA2 Ras 
This model is an annotated version of the synaptic signaling network.
The primary reference is Bhalla US and Iyengar R. Science (1999) 283(5400):381-7 but several of the model pathways have been updated Bhalla US, Ram PT, Iyengar R. Science. 2002 Aug 9;297(5583):1018-23.

DAG-Ca-PLA2* acting as a Molecule in  
3d_fold_model Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
DAG-Ca-PLA2*3d_fold_model
Accession No. : 8
PLA2
Pathway No. : 57
01000No

DAG-Ca-PLA2* acting as an Enzyme in  
3d_fold_model Network
Enzyme Molecule /
Enzyme Activity
Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
DAG-Ca-PLA2* /
kenz
3d_fold_model
Accession No. : 8
PLA2
Pathway No. : 57
20604explicit E-S complexSubstrate
APC

Product
AA
10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 * k3

DAG-Ca-PLA2* acting as a Product in a reaction in  
3d_fold_model Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
DAG-Ca-PLA2-act3d_fold_model
Accession No. : 8
PLA2
Pathway No. : 57
0.003
(uM^-1 s^-1)
4
(s^-1)
Kd(bf) = 1333.3333(uM)-Substrate
DAG
PLA2-Ca*

Product
DAG-Ca-PLA2*
27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.



Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.