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Molecule Parameter List for CaTransp

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CaTransp participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000011

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
fig2_egfr1Network
Shared_Object_fig2_egfr PKC PLA2 
PLCbeta Gq MAPK 
Ras EGFR Sos 
PLC_g CaRegulation 
This network was used to generate figure 2 in Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It consists of the MAPK cascade in a feedback loop with PKC, and receives input from the EGFR in the synapse.
Demonstration script files for generating the figures in the paper, including figure 2, are available here.

CaTransp acting as a Molecule in  
fig2_egfr Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
CaTranspfig2_egfr
Accession No. : 1
CaRegulation
Pathway No. : 11
0.011000No

CaTransp acting as a Substrate in a reaction in  
fig2_egfr Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
  • Ca-bind-to-Trans
    p
  • fig2_egfr
    Accession No. : 1
    CaRegulation
    Pathway No. : 11
    3600
    (uM^-2 s^-1)
    144
    (s^-1)
    Kd(af) = 0.2(uM)-Substrate
    Ca
    Ca
    CaTransp

    Product
    CaTransp-2Ca

    CaTransp acting as a Product in a reaction in  
    fig2_egfr Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    CaTraspATPasefig2_egfr
    Accession No. : 1
    CaRegulation
    Pathway No. : 11
    25
    (s^-1)
    0
    (#^-2 s^-1)
    Not applicable**-Substrate
    CaTransp-2Ca

    Product
    Ca-sequester
    Ca-sequester
    CaTransp
    ** This is a trasport reation between compartments of different volumes. Therefore Kd is not applicable. Please Note Kf, Kb units are in number of molecules instead of concentration



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.