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Molecule Parameter List for temp-PIP2

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
temp-PIP2 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences250000500

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Ajay_Bhalla_
    2007_ReacDiff3
    		• 84NetworkShared_Object_Ajay_Bhalla_2007_ReacDiff3,  PKC,  PLA2,  
    MAPK,  PLA2,  Ras,  CaM,  chain,  kinetics,  PKC,  MAPK,  Ras,  CaM,  kinetics[1],  
    PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[2],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[3],  
    PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[4],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[5],  
    PKC,  PLA2,  MAPK,  Ras,  MAPK,  CaM,  kinetics[6],  PKC,  PLA2,  MAPK,  Ras,  
    CaM,  kinetics[7],  PKC,  PLA2,  MAPK,  Ras,  CaM,  PKC,  kinetics[8],  PLA2,  
    MAPK,  Ras,  CaM,  kinetics[9],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[10],  
    PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[11],  PKC,  PLA2,  MAPK,  Ras,  CaM,  
    kinetics[12],  PKC,  PLA2,  Ras,  CaM,  kinetics[13],  PKC,  PLA2,  MAPK,  
    Ras,  CaM,  kinetics[14],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[15],  
    PKC,  PLA2,  MAPK,  Ras,  kinetics[16],  CaM,  PKC,  PLA2,  MAPK,  Ras,  CaM,  
    kinetics[17],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[18],  PKC,  PLA2,  
    MAPK,  Ras,  CaM,  kinetics[19],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[20],  
    PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[21],  PKC,  PLA2,  MAPK,  Ras,  CaM,  
    kinetics[22],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[23],  PKC,  PLA2,  
    MAPK,  Ras,  CaM 
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_bistable model. The original single-compartment model is repeated 25 times.
    In addition, a subset (33 out of 50) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. Here D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) so the kf and kb of this reaction for these 10 micron compartments are both 0.001/sec.
    The basal calcium level in this model is held at 95 nM which is rather close to threshold for the flip to the active state. This is necessary to sustain active propagation of activation.
    The stimulus file bis6-propgn_D1e-13_FigEF which was used for the model to replicate Figure 4E and 4F from the paper.

    temp-PIP2 acting as a Molecule in      Ajay_Bhalla_2007_ReacDiff3 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)    		Volume
    (fL)    		Buffered
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics
    Pathway No. : 926    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[1]
    Pathway No. : 931    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[2]
    Pathway No. : 937    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[3]
    Pathway No. : 943    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[4]
    Pathway No. : 949    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[5]
    Pathway No. : 955    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[12]
    Pathway No. : 998    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[6]
    Pathway No. : 962    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[7]
    Pathway No. : 968    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[8]
    Pathway No. : 975    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[9]
    Pathway No. : 980    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[10]
    Pathway No. : 986    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[11]
    Pathway No. : 992    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[13]
    Pathway No. : 1003    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[14]
    Pathway No. : 1009    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[15]
    Pathway No. : 1015    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[16]
    Pathway No. : 1020    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[17]
    Pathway No. : 1027    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[18]
    Pathway No. : 1033    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[19]
    Pathway No. : 1039    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[20]
    Pathway No. : 1045    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[21]
    Pathway No. : 1051    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[22]
    Pathway No. : 1057    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
    temp-PIP2
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[23]
    Pathway No. : 1063    		2.5125.7Yes
    This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....

    temp-PIP2 acting as a Substrate in a reaction in      Ajay_Bhalla_2007_ReacDiff3 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 920    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    2
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 920    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    3PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 922    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    4
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 922    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    5PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 933    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    6
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 933    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    7PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 939    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    8
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 939    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    9PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 945    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    10
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 945    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    11PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 951    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    12
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 951    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    13PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 957    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    14
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 957    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    15PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 964    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    16
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 964    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    17PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 970    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    18
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 970    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    19PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 976    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    20
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 976    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    21PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 982    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    22
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 982    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    23PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 988    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    24
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 988    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    25PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 994    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    26
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 994    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    27PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1000    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    28
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1000    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    29PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1005    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    30
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1005    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    31PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1011    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    32
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1011    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    33PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1017    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    34
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1017    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    35PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1023    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    36
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1023    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    37PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1029    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    38
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1029    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    39PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1035    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    40
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1035    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    41PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1041    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    42
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1041    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    43PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1047    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    44
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1047    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    45PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1053    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    46
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1053    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    47PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1059    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    48
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1059    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    49PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1065    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    50
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1065    		0.012
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*


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