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Molecule Parameter List for int1

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
int1 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1010000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
MAPK_osc27Pathway
MAPK 
This MAPK model is based on Boris N. Kholodenko Eur J Biochem. (2000) 267(6):1583-8 for data from Xenopus oocytes extracts.

int1 acting as a Molecule in  
MAPK_osc Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
int1MAPK_osc
Accession No. : 27
MAPK
Pathway No. : 139
0.0010.0016667No
This is the intermediate enzyme which catalyses the dephosphorylation of MKKK-P to MKKK. The concentration is set to 1 nM based on from Kholodenko, 2000

int1 acting as an Enzyme in  
MAPK_osc Network
Enzyme Molecule /
Enzyme Activity
Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
int1 /
2
MAPK_osc
Accession No. : 27
MAPK
Pathway No. : 139
0.0080.254Classical Michaelis-Menten
V = Etot.S.Kcat/Km+S
Substrate
MKKK-P

Product
MKKK
Km is 8nM and Vmax is 0.25nM.s-1 from Kholodenko, 2000.



Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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