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Enzyme List for pathway PP1 (Pathway Number 237) in Accession AMPAR_traff_model0 (Accession Number 59) |
Entries are grouped according to Pathway Number and they are alternately color coded using and color.Further ordering can be done according to header. arrow indicates that ordering is done according to ascending or descending order. |
| Enzyme Molecule / Enzyme Activity | Pathway Name / Pathway No. ![]() | Km (uM) | kcat (s^-1) | Ratio (k2/k3) | Enzyme Type | Reagents | ||
| 1 | PP2A / | PP1 Pathway No. 237 | 15.9999 | 2 | 4.1667 | explicit E-S complex | Substrate: I1* Product : I1 | |
| PP2A does most of the dephosph of I1 at basal Ca levels. See the review by Cohen in Ann Rev Biochem 1989. For now, lets halve Km. k1 was 3.3e-6, now 6.6e-6 | ||||||||
| 2 | PP2A / 1-I* | PP1 Pathway No. 237 | 15.9999 | 2 | 4.1667 | explicit E-S complex | Substrate: PP1-I1* Product : PP1-I1 | |
| k1 changed from 3.3e-6 to 6.6e-6 | ||||||||
| 3 | PP2A / PP2A-dephosph-I1 _ PSD | PP1 Pathway No. 237 | 15.9999 | 2 | 4.1667 | explicit E-S complex | Substrate: I1* Product : I1 | |
| PP2A does most of the dephosph of I1 at basal Ca levels. See the review by Cohen in Ann Rev Biochem 1989. For now, lets halve Km. k1 was 3.3e-6, now 6.6e-6 | ||||||||
| 4 | PP2A / PP2A-dephosph-PP 1-I*_ PSD | PP1 Pathway No. 237 | 15.9999 | 2 | 4.1667 | explicit E-S complex | Substrate: PP1-I1* Product : PP1-I1 | |
| k1 changed from 3.3e-6 to 6.6e-6 | ||||||||
| 5 | PP1-active / Deph-thr286 | PP1 Pathway No. 237 | 5.09905 | 2.5 | 4 | explicit E-S complex | Substrate: CaMKII-thr286*-C aM Product : CaMKII-CaM | |
| 6 | PP1-active / Deph-thr286b | PP1 Pathway No. 237 | 5.09905 | 2.5 | 4 | explicit E-S complex | Substrate: CaMKII-thr286 Product : CaMKII | |
| 7 | PP1-active / Deph-thr305 | PP1 Pathway No. 237 | 5.09905 | 2.5 | 4 | explicit E-S complex | Substrate: CaMKII*** Product : CaMKII-thr286 | |
| 8 | PP1-active / Deph-thr286c | PP1 Pathway No. 237 | 5.09905 | 2.5 | 4 | explicit E-S complex | Substrate: CaMKII*** Product : CaMK-thr305 | |
| 9 | PP1-active / Deph-thr305a | PP1 Pathway No. 237 | 5.09905 | 2.5 | 4 | explicit E-S complex | Substrate: CaMK-thr305 Product : CaMKII | |
and
color.
arrow indicates that ordering is done according to ascending or descending order.