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Result: 1 - 9 of 9 rows are displayed

Molecule List for pathway PKA (Pathway Number 17) in Accession fig3_CaMKII (Accession Number 2)

Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.
arrow indicates that ordering is done according to ascending or descending order.
The entries are grouped according to Pathway Number and are alternately color coded using  and  color.
  NameAccession
Type
Initial
Conc.

(uM)
Volume
(fL)
BufferedSum Total Of
1 R2C2Network0.50No
    PKA: Protein kinase activated by cAMP.
R2C2 complex consists of 2 catalytic (C) subunits, and the R-dimer. There are two types of cAMP binding sites termed A and B according to the rate with which they exchange bound labelled nucleotide.
Dagfinn Ogreid and Stein Ove Doskeland (1981) Int.J.Biochem. 13(1):1-19
Physiological concentration of PKA = 0.59 uM (cardiac myocyte)
Jeffrey J. Saucerman et al (2003) J.Biol.Chem. 278(48):47997-48003
2 R2C2-cAMPNetwork00No
    R2C2 complex consisting of 2 catalytic (C) subunits, and the R-dimer with one molecule of cAMP bound to site B1 on the regulatory subunit.
3 R2C2-cAMP2Network00No
    R2C2 complex consisting of 2 catalytic (C) subunits, and the R-dimer with one molecule of cAMP bound to each of the B sites on the regulatory subunit.
4 R2C2-cAMP3Network00No
    R2C2 complex consisting of 2 catalytic (C) subunits, and the R-dimer with 3 cAMP molecules bound to it.
5 R2C2-cAMP4Network00No
    R2C2 complex consisting of 2 catalytic (C) subunits, and the R-dimer with 4 cAMP molecules bound to it. All the regulatory subunits now have cAMP bound. This state is ready to dissociate and to release the catalytic subunit.
6 R2C-cAMP4Network00No
    R2C1 complex consisting of 1 catalytic (C) subunit, and the R-dimer with 4 cAMP molecules bound to it.
7 R2-cAMP4Network00No
    R-dimer is bound to 4 cAMP molecules.
8 PKA-inhibitorNetwork0.250No
9 inhibited-PKANetwork00No

 
Result: 1 - 9 of 9 rows are displayed



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