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Result: 1 - 14 of 14 rows are displayed

Molecule List for pathway CaM (Pathway Number 236) in Accession AMPAR_traff_model0 (Accession Number 59)

Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.
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The entries are grouped according to Pathway Number and are alternately color coded using  and  color.
  NameAccession
Type
Initial
Conc.

(uM)
Volume
(fL)
BufferedSum Total Of
1 CaMNetwork26.33330No
    There is a LOT of this in the cell: upto 1% of total protein mass. (Alberts et al) Say 25 uM. Meyer et al Science 256 1199-1202 1992 refer to studies saying it is comparable to CaMK levels.
2 neurogranin-CaMNetwork00No
3 neurogranin*Network00No
    The phosph form does not bind CaM (Huang et al ABB 305:2 570-580 1993)
4 neurograninNetwork100No
    Also known as RC3 and p17 and BICKS. Conc in brain >> 2 uM from Martzen and Slemmon J neurosci 64 92-100 1995 but others say less without any #s. Conc in dend spines is much higher than overall, so it could be anywhere from 2 uM to 50. We will estimate 10 uM as a starting point. Gerendasy et al JBC 269:35 22420-22426 1994 have a skeleton model (no numbers) indicating CaM-Ca(n) binding.
5 CaM-PSDNetwork26.33330No
    There is a LOT of this in the cell: upto 1% of total protein mass. (Alberts et al) Say 25 uM. Meyer et al Science 256 1199-1202 1992 refer to studies saying it is comparable to CaMK levels.
6 

  • neurogranin-CaM_
    PSD
  • Network00No
    7 neurogranin_PSDNetwork100No
        Also known as RC3 and p17 and BICKS. Conc in brain >> 2 uM from Martzen and Slemmon J neurosci 64 92-100 1995 but others say less without any #s. Conc in dend spines is much higher than overall, so it could be anywhere from 2 uM to 50. We will estimate 10 uM as a starting point. Gerendasy et al JBC 269:35 22420-22426 1994 have a skeleton model (no numbers) indicating CaM-Ca(n) binding.
    8 
  • neurogranin*_
    PSD
  • Network00No
        The phosph form does not bind CaM (Huang et al ABB 305:2 570-580 1993)
    9 CaM-TR2-Ca2Network00No
        This is the intermediate where the TR2 end (the high-affinity end) has bound the Ca but the TR1 end has not.
    10 CaM-Ca3Network00No
    11 CaM-Ca4-PSDNetwork00No
    12 CaM-Ca3-PSDNetwork00No
    13 CaM-TR2-Ca2-PSDNetwork00No
        This is the intermediate where the TR2 end (the high-affinity end) has bound the Ca but the TR1 end has not.
    14 CaM-Ca4Network00No

     
    Result: 1 - 14 of 14 rows are displayed



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