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Molecule List for pathway PKA (Pathway Number 326) in Accession Ajay_Bhalla_2004_PKM_Tuning (Accession Number 76)

Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.
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The entries are grouped according to Pathway Number and are alternately color coded using  and  color.
  NameAccession
Type
Initial
Conc.

(uM)
Volume
(fL)
BufferedSum Total Of
1 R2C2Network0.50No
    This is the R2C2 complex, consisting of 2 catalytic (C) subunits, and the R-dimer. See Taylor et al Ann Rev Biochem 1990 59:971-1005 for a review. The Doskeland and Ogreid review is better for numbers. Amount of PKA is about .5 uM.
2 R2C2-cAMPNetwork00No
    CoInit was .0624
3 R2C2-cAMP2Network00No
4 R2C2-cAMP3Network00No
5 R2C2-cAMP4Network00No
6 R2C-cAMP4Network00No
7 R2-cAMP4Network00No
    Starts at 0.15 for the test of fig 6 in Smith et al, but we aren't using that paper any more.
8 PKA-inhibitorNetwork0.250No
    About 25% of PKA C subunit is dissociated in resting cells without having any noticable activity. Doskeland and Ogreid Int J biochem 13 pp1-19 suggest that this is because there is a corresponding amount of inhibitor protein.
9 inhibited-PKANetwork00No

 
Result: 1 - 9 of 9 rows are displayed



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