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Molecule List for pathway CaMKII (Pathway Number 174) in Accession CaMKII (Accession Number 33)

Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.

arrow indicates that ordering is done according to ascending or descending order.
The entries are grouped according to Pathway Number and are alternately color coded using

and

color.

	Name	Accession Type	Initial Conc. (uM)	Volume (fL)	Buffered	Sum Total Of
1	Autonomous	Network	0	0	No	-
2	CaMKII	Network	12.7325	0	No	-
	Init level is 100 holoenzymes of 10 subunits each.
3	CaMKII-CaM	Network	0	0	No	-
4	CAMKII-CaMCa	Network	0	0	No	-
5	CaMKII-CaMCa2	Network	0	0	No	-
6	CaMKII-CaMCa3	Network	0	0	No	-
7	CaMKII-CaMCa4	Network	0	0	No	-
8	Capped	Network	0	0	No	-
9	Tot-active-CaMKI I	Network	0	0	No	CaMKII-CaMCa4 Trapped-T286 Capped Autonomous
10	Total_CaMKII	Network	127.325	0	No	-
	This is not directly in the Holmes model. It is a trick used in GENESIS/Kinetikit to scale activity down for intramolecular reactions. Here it is used to scale the autophosph reactions such that only neighboring subunits will phosphorylate each other. This is done by scaling down the actual conc (in the enzyme parent, Tot-active-CaMKII) by the total conc such that instead of a conc, we the fraction of nearby subunits that will be active. Note that this conc of 10000 CaMKII subunits is 10 times the true conc, since only 1/10 of the molecules are neighboring molecules.
11	Trapped-T286	Network	0	0	No	-

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