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Accession Type:
Network
AMPAR_traff_
model1
Shared_Object_
AMPAR_traff_
model1
CaMKII
CaM
PP1
 Molecule
 Enzyme
 Reaction
PP2B
PP1_PSD
PKA
AC
AMPAR
AMPAR_memb

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Molecule List for pathway PP1 (Pathway Number 247)

 Name Initial Conc. (uM) Volume (fL) Buffered
1I11.80.09No
    I1 is a 'mixed' inhibitor, but at high enz concs it looks like a non-compet inhibitor (Foulkes et al Eur J Biochem 132 309-313 9183). We treat it as non-compet, so it just turns the enz off without interacting with the binding site. Cohen et al ann rev bioch refer to results where conc is 1.5 to 1.8 uM. In order to get complete inhib of PP1, which is at 1.8 uM, we need >= 1.8 uM.
2I1*00.09No
    Dephosph is mainly by PP2B
3PP1-active1.80.09No
    Cohen et al Meth Enz 159 390-408 is main source of info conc = 1.8 uM
4PP1-I100.09No
   
5PP1-I1*00.09No
   
6PP2A0.11110.09No
   


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