NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Accession Type:
Network
CaMKII_noPKA_
model3
Shared_Object_
CaMKII_noPKA_
model3
CaMKII
CaM
PP1
 Molecule
 Reaction
PP2B
PP1_PSD

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Molecule List for pathway PP1 (Pathway Number 260)

 Name Initial Conc. (uM) Volume (fL) Buffered
1I11.80.09No
    I1 is a 'mixed' inhibitor, but at high enz concs it looks like a non-compet inhibitor (Foulkes et al Eur J Biochem 132 309-313 9183). We treat it as non-compet, so it just turns the enz off without interacting with the binding site. Cohen et al ann rev bioch refer to results where conc is 1.5 to 1.8 uM. In order to get complete inhib of PP1, which is at 1.8 uM, we need >= 1.8 uM.
2I1*00.09No
    Dephosph is mainly by PP2B
3PP1-I100.09No
   
4PP1-I1*00.09No
   


Pathway Details  Molecule List  Enzyme List   Reaction List  


Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.