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Accession Type:
Network
AMPAR_CaMKII_
weak_coupling
Shared_Object_
AMPAR_CaMKII_
weak_coupling
CaMKII
CaM
PP1
 Molecule
 Reaction
PP2B
PP1_PSD
AMPAR
PKA
AC
AMPAR_memb
PP1_CaMKII_PSDPP1_CaMKII_PSD
CaMKII_PSD

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Molecule List for pathway PP1 (Pathway Number 284)

 Name Initial Conc. (uM) Volume (fL) Buffered
1I11.80.09No
    I1 is a 'mixed' inhibitor, but at high enz concs it looks like a non-compet inhibitor (Foulkes et al Eur J Biochem 132 309-313 9183). We treat it as non-compet, so it just turns the enz off without interacting with the binding site. Cohen et al ann rev bioch refer to results where conc is 1.5 to 1.8 uM. In order to get complete inhib of PP1, which is at 1.8 uM, we need >= 1.8 uM.
2I1*00.09No
    Dephosph is mainly by PP2B
3PP1-I100.09No
   
4PP1-I1*00.09No
   


Pathway Details  Molecule List  Enzyme List   Reaction List  


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