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Accession Type:
Network
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Shared_Object_
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PKC
PLA2
PLCbeta
Gq
MAPK
Ras
CaMKII
 Molecule
 Enzyme
 Reaction
CaM
PP1
PP2B
PKA
AC

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Reaction List for pathway CaMKII (Pathway Number 26)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 basal-activitykf
(s^-1)
0
(s^-1)
--CaMKII
CaMKII-thr286
2 CaMK-thr286-bind
-CaM
kf
(uM^-1 s^-1)
0.1
(s^-1)
Kd(bf) = 0.0001(uM)-CaMKII-thr286
CaM-Ca4
  • CaMKII-thr286*-C
    aM

  • 3 CaMKII-bind-CaMkf
    (uM^-1 s^-1)
    5
    (s^-1)
    Kd(bf) = 0.1(uM)-CaM-Ca4
    CaMKII
    CaMKII-CaM


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    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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