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Accession Type:
Network
AKT
Shared_Object_
AKT
AKT_mod
 Molecule
 Enzyme
 Reaction

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Reaction List for pathway AKT_mod (Pathway Number 1086)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 PIP3_bind_AKTkf
(uM^-1 s^-1)
0.089
(s^-1)
Kd(bf) = 0.002(uM)-AKT
PIP3
PIP3_AKT
2 PIP3_bind_PDK1kf
(uM^-1 s^-1)
0.98
(s^-1)
Kd(bf) = 1.4(uM)-PDK1
PIP3
PIP3_PDK1
3 TSC1-2_
dephospho
kf
(s^-1)
0
(s^-1)
--TSC1-TSC2*
TSC1-TSC2


Pathway Details   Molecule List   Enzyme List  Reaction List  


Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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