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Accession Type:
Network
4EBP
Shared_Object_
4EBP
mTOR_model
4E-BP_mod
 Molecule
 Reaction

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Reaction List for pathway 4E-BP_mod (Pathway Number 1092)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 eIF4E-BP2_dissokf
(s^-1)		1
(uM^-1 s^-1)		Kd(cb) = 0.25(uM)-
  • eIF4E_4E-BP_
    t37_46_s65
    		• eIF4E
  • 4E-BP_thr37_46_
    s65
    • 2 eIF4E_bind_BP2kf
    (uM^-1 s^-1)    		0.15
    (s^-1)    		Kd(bf) = 0.003(uM)-4E-BP
    eIF4E
    		eIF4E-BP


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