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Accession Type:
Network
fig2_egfr
Shared_Object_
fig2_egfr
PKC
PLA2
PLCbeta
Gq
MAPK
Ras
EGFR
Sos
PLC_g
CaRegulation
 Molecule
 Enzyme
 Reaction

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Reaction List for pathway CaRegulation (Pathway Number 11)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 Ca-bind-to-Trans
p
kf
(uM^-2 s^-1)
144
(s^-1)
Kd(af) = 0.2(uM)-Ca
Ca
CaTransp
CaTransp-2Ca
2 CaTraspATPasekf
(s^-1)
0
(#^-2 s^-1)
Not applicable**-CaTransp-2Ca
CaTransp
Ca-sequester
Ca-sequester
3 inactivate_cap_
Ca
kf
(#^-2 s^-1)
1
(s^-1)
Not applicable**-Ca-sequester
Ca-sequester
  • capacitive_Ca_
    entry*

  • inact_cap_entry
    4 IP3Rbindkf
    (uM^-3 s^-1)
    1
    (s^-1)
    Kd(af) = 7.736(uM)-IP3R
    IP3
    IP3
    IP3
    IP3R*


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