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Accession Type:
Network
Osc_Ca_
IP3metabolism
MIPP
CaMKII
CaM
PKC
IP3-3K
Gq
PLCbeta
134_dephos
145_dephos
IP4-system
IHP-system
1345_dephos
CaRegulation
 Molecule
 Enzyme
 Reaction
Othmer-Tang-mode
l

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Parameters for CaRegulation (Pathway Number 132)

Pathway Layout

Pathway Basic Parameters

Pathway NameCaRegulation
Pathway Entry Number 132
Accession Number 24
Accession Name Osc_Ca_IP3metabolism
Species Generic mammalian
Tissue Brain - Neuronal
CellCompartmentCytosol
Related Pathways 11, 86, 110, 149, 170
Notes Modified Ca Regulation model for the IP3 metabolism network. This model is used with the Othmer-Tang model for IP3 receptor kinetics, to generate cytosolic Ca oscillations. Channel kinetics of the IP3 receptor, ER-leak, ER-pump (or CaATPase) and Capacitative Ca entry have been modified to allow for Ca oscillations characterized in the Othmer-Tang model (Tang et al, Biophys J 70, 1996: 246-63). Kinetics of store Ca buffering by Calsequestrin have not been changed.

Statistics

16
1
9

Conversion format

This pathway is part of accession 24 and is completely specified in the file acc24.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc24.g   
GENESIS Format (Annotated version)    Anno_acc24.g   


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