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Reaction List for pathway MAPK (Pathway Number 139) | | Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
| | Name | Kf | Kb | Kd | tau | Substrate | Product | | 1 |
Neg_feedback | kf
(uM^-1 s^-1) | 0.009
(s^-1) | Kd(bf) = 0.009(uM) | - | MAPK-PP
Ras-MKKKK
| inactiveRas-MKKK
| | | From Kholodenko, 2000 Eur J Biochem 267 the Kd is 9 nM. We use a rather fast Kf of 1/sec/uM so that equilibrium is maintained. |
Pathway Details Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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