 |  |  CaRegulation |
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Reaction List for pathway 145_dephos (Pathway Number 166) | | Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
| | Name | Kf | Kb | Kd | tau | Substrate | Product | | 1 |
4pase-off | kf
(s^-1) | 0.0021
(uM^-1 s^-1) | Kd(cb) = 0.0001(uM) | - | ip1_4pase_cmplx
| IP1_pase
inositol
| | | Kf = Vmax for Ins(4)P1 4-phosphatase: Gee et al, Biochem J 249, 1988. Kb adjusted to generate reported basal levels of Ins(4)P1 = 10% of Ins(1)P1 ~ 4uM | | 2 |
4pase-on | kf
(uM^-1 s^-1) | 157.32
(s^-1) | Kd(bf) = 152(uM) | - | IP1(4)
IP1_pase
| ip1_4pase_cmplx
| | | Rates derived from Ins(4)P1 4-phosphatase Km: Gee et al, Biochem J 249; 1988 | | 3 |
Ca-inhib-1pase | kf
(uM^-1 s^-1) | 6
(s^-1) | Kd(bf) = 5.9999(uM) | - | IP_1pase
Ca
| Ca-1pase-cmplx
| | | Ki from Inhorn & Majerus, BiochemJ 262(33); 1987: 15946-52 | | 4 |
IP5-inhib-5pase | kf
(uM^-1 s^-1) | 45
(s^-1) | Kd(bf) = 44.9991(uM) | - | IP5(13456)
IP_5pase1
| IP5-5pase-cmplx
| | | from Hoer and Oberdisse, Biochem J 278; 1991: 219-224 | | 5 |
IP6-inhib-5pase | kf
(uM^-1 s^-1) | 16
(s^-1) | Kd(bf) = 15.9997(uM) | - | IP6
IP_5pase1
| IP6-5pase-inhib
| | | from Hoer and Oberdisse, Biochem J 278; 1991: 219-224 |
Pathway Details Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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