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Accession Type:
Network
CaMKII_2003
Shared_Object_
CaMKII_2003
CaMKII
CaM
PP1
 Molecule
 Reaction
PP2B

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Molecule List for pathway PP1 (Pathway Number 204)

 Name Initial Conc. (uM) Volume (fL) Buffered
1I11.81000No
    I1 is a 'mixed' inhibitor, but at high enz concs it looks like a non-compet inhibitor (Foulkes et al Eur J Biochem 132 309-313 9183). We treat it as non-compet, so it just turns the enz off without interacting with the binding site. Cohen et al ann rev bioch refer to results where conc is 1.5 to 1.8 uM. In order to get complete inhib of PP1, which is at 1.8 uM, we need >= 1.8 uM.
2I1*0.0011000No
    Dephosph is mainly by PP2B
3PP1-I101000No
   
4PP1-I1*01000No
   


Pathway Details  Molecule List  Enzyme List   Reaction List  


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