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Accession Type:
Network
MAPK_network_
2003
Shared_Object_
MAPK_network_
2003
PKC
PLA2
PLCbeta
 Molecule
 Enzyme
 Reaction
Gq
MAPK
Ras
EGFR
Sos
PLC_g
CaMKII
CaM
PP1
PP2B
PKA
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Molecule List for pathway PLCbeta (Pathway Number 209)

 Name Initial Conc. (uM) Volume (fL) Buffered
1Inositol01000Yes
   
2PC00.0016667Yes
    Phosphatidylcholine is the main (around 55%) metabolic product of DAG, follwed by PE (around 25%). Ref is Welsh and Cabot, JCB35:231-245(1987)
3PLC0.81000No
    Total PLC = 0.8 uM see Ryu et al JBC 262 (26) pp 12511 1987
4PLC-Ca01000No
   
5PLC-Ca-Gq01000No
    This should really be labelled PLC-G*GTP-Ca. This is the activated form of the enzyme. Mahama and Linderman assume that the IP3 precursors are not rate-limiting, but I will include those for completeness as they may be needed later.
6PLC-Gq01000No
   


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