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Accession Type:
Network
CaMKII_noPKA_
model3
Shared_Object_
CaMKII_noPKA_
model3
CaMKII
CaM
PP1
 Molecule
 Reaction
PP2B
PP1_PSD

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Reaction List for pathway PP1 (Pathway Number 260)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 dissoc-PP1-I1kf
(s^-1)
0
(uM^-1 s^-1)
--PP1-I1
PP1-active
I1
  Let us assume that the equil in this case is very far over to the right. This is probably safe.
2 Inact-PP1kf
(uM^-1 s^-1)
0.1
(s^-1)
Kd(bf) = 0.0002(uM)-I1*
PP1-active
PP1-I1*
  K inhib = 1nM from Cohen Ann Rev Bioch 1989, 4 nM from Foukes et al Assume 2 nM. kf /kb = 8.333e-4


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