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Accession Type:
Network
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PKC
PLA2
PLCbeta
Gq
MAPK
Ras
CaMKII
CaM
 Molecule
 Reaction
PP1
PP2B
PKA
AC

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Reaction List for pathway CaM (Pathway Number 27)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 CaM-Ca3-bind-Cakf
(uM^-1 s^-1)		10
(s^-1)		Kd(bf) = 21.5054(uM)-CaM-Ca3
Ca
CaM-Ca4
2 CaM-TR2-bind-Cakf
(uM^-2 s^-1)		72
(s^-1)		Kd(af) = 1(uM)-CaM
Ca
Ca
CaM-TR2-Ca2
3 CaM-TR2-Ca2-bind
-Ca		kf
(uM^-1 s^-1)		10
(s^-1)		Kd(bf) = 2.7778(uM)-CaM-TR2-Ca2
Ca
CaM-Ca3
4 dephosph-neurogr
anin		kf
(s^-1)		0
(s^-1)		--neurogranin*
neurogranin
5 neurogranin-bind
-CaM		kf
(uM^-1 s^-1)		1
(s^-1)		Kd(bf) = 3.3333(uM)-neurogranin
CaM
neurogranin-CaM


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Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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