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Accession Type:
Network
AMPAR_CaMKII_
strong_coupling
Shared_Object_
AMPAR_CaMKII_
strong_coupling
CaMKII
CaM
 Molecule
 Reaction
PP1
AMPAR_memb
PP2B
PKA
AC
PP1_PSD
AMPAR

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Parameters for CaM (Pathway Number 273)

Pathway Layout

Pathway Basic Parameters

Pathway NameCaM
Pathway Entry Number 273
Accession Number 64
Accession Name AMPAR_CaMKII_strong_coupling
Species General Mammalian
Tissue Neuronal
CellCompartmentSynaptic Spine, Postsynaptic Density
Related Pathways 14, 27, 81, 107, 122, 146, 160, 173, 203, 217, 236, 246, 259, 265, 283, 323, 340, 358, 368, 373, 379, 386, 392, 398, 405, 411, 418, 423, 428, 434, 440, 446, 452, 458, 464, 470, 476, 482, 488, 494, 500, 506, 512, 518, 524, 530, 537, 543, 549, 555, 561, 568, 573, 579, 585, 591, 597, 603, 609, 615, 621, 627, 633, 639, 645, 651, 657, 663, 669, 675, 681, 688, 695, 701, 706, 712, 718, 724, 730, 736, 742, 748, 754, 760, 766, 772, 778, 784, 790, 796, 802, 808, 814, 820, 826, 832, 838, 844, 850, 856, 862, 868, 874, 880, 886, 892, 898, 904, 910, 916, 924, 930, 936, 942, 948, 954, 961, 967, 973, 979, 985, 991, 997, 1002, 1008, 1014, 1021, 1026, 1032, 1038, 1044, 1050, 1056, 1062, 1068, 1094
Notes  This is a model of tight coupling between the AMPAR trafficking bistability, and the CaMKII autophosphorylation bistability. In this model, the CaMKII activity is self sustaining only when AMPAR is turned on. Further, CaMKII turns on when AMPAR is turned on.

Statistics

Enzyme sites
8
0
9

Conversion format

This pathway is part of accession 64 and is completely specified in the file acc64.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc64.g   
MATLAB format    acc64.m   
SBML format    acc64.xml   


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Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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