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Accession Type:
Network
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Shared_Object_
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PKC
PLA2
PLCbeta
Gq
MAPK
Ras
CaMKII
CaM
PP1
PP2B
PKA
AC
 Molecule
 Enzyme
 Reaction

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Reaction List for pathway AC (Pathway Number 31)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 CaM-bind-AC1kf
(uM^-1 s^-1)
1
(s^-1)
Kd(bf) = 0.02(uM)-CaM-Ca4
AC1
AC1-CaM
2 CaM_bind_PDE1kf
(uM^-1 s^-1)
5
(s^-1)
Kd(bf) = 0.0069(uM)-PDE1
CaM-Ca4
CaM.PDE1
3 dephosph-AC2kf
(s^-1)
0
(s^-1)
--AC2*
AC2
4 dephosph-PDEkf
(s^-1)
0
(s^-1)
--cAMP-PDE*
cAMP-PDE
5 Gs-bind-AC1kf
(uM^-1 s^-1)
1
(s^-1)
Kd(bf) = 0.0079(uM)-Gs-alpha
AC1
AC1-Gs
6 Gs-bind-AC2kf
(uM^-1 s^-1)
1
(s^-1)
Kd(bf) = 0.002(uM)-AC2
Gs-alpha
AC2-Gs
7 Gs-bind-AC2*kf
(uM^-1 s^-1)
1
(s^-1)
Kd(bf) = 0.0012(uM)-Gs-alpha
AC2*
AC2*-Gs


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