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Accession Type:
Network
fig2_egfr
Shared_Object_
fig2_egfr
PKC
PLA2
PLCbeta
Gq
MAPK
Ras
EGFR
Sos
 Molecule
 Reaction
PLC_g
CaRegulation

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Parameters for Sos (Pathway Number 9)

Pathway Layout

Pathway Basic Parameters

Pathway NameSos
Pathway Entry Number 9
Accession Number 1
Accession Name fig2_egfr
Species Generic mammalian
Tissue Brain
CellCompartmentSurface - Nucleus
Related Pathways 33, 78, 180, 214, 233, 320, 337, 355
Notes This network was used to generate figure 2 in Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It consists of the MAPK cascade in a feedback loop with PKC, and receives input from the EGFR in the synapse.
Demonstration script files for generating the figures in the paper, including figure 2, are available here.

Statistics

Enzyme sites
5
0
4

Conversion format

This pathway is part of accession 1 and is completely specified in the file acc1.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc1.g   
GENESIS Format (Annotated version)    Anno_acc1.g   


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Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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