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Default ordering is done according to Pathway Name.Table header can be used for changing the default ordering. indicates that ordering is done according to ascending or descending order.Entries are color tagged depending on Network or Pathway ![]() |
| Pathway Name Pathway No. | Accession Name Accession No. | Accession Type ![]() | Pathway statistics | pp2b statistics | Source Entry Date | ||||||||||||||
| 1 | PP2B Pathway No. 16 | fig3_CaMKII Accession No. 2 | Network | Molecule = 5 Enzyme = 0 Reaction = 5 | Molecule = 0 Enzyme = 0 Reaction = 0 | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/ 2001-11-07 00:00:00 | |||||||||||||
| Related Pathway: 29, 83, 205, 219, 238, 248, 261, 267, 276, 285, 325, 342, 360 | |||||||||||||||||||
| This is the model file for figure 3 from Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It is a model of the Ca activation of CaMKII and other CaM-activated enzymes. It includes the regulatory phosphatases PP1 and PP2B (Calcineurin) acting on CaMKII and also includes CaM-activated adenylyl cyclase and PKA in the synapse. Demonstration script files for generating the figures in the paper, including figure 3, are available here. | |||||||||||||||||||
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| 2 | PP2B Pathway No. 29 | fig4_synapse Accession No. 3 | Network | Molecule = 5 Enzyme = 0 Reaction = 5 | Molecule = 0 Enzyme = 0 Reaction = 0 | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/ 2001-11-07 00:00:00 | |||||||||||||
| Related Pathway: 16, 83, 205, 219, 238, 248, 261, 267, 276, 285, 325, 342, 360 | |||||||||||||||||||
| This is the composite model of 4 kinases: PKC, MAPK, PKA and CaMKII and numerous regulatory pathways involved in synaptic signaling. From Bhalla US and Iyengar R. Science (1999) 283(5400):381-7.This model comes from figure 4 of that paper. Demonstration script files for generating the figures in the paper, including figure 4, are available here. | |||||||||||||||||||
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| 3 | PP2B Pathway No. 83 | Synaptic_ Network Accession No. 16 | Network | Molecule = 5 Enzyme = 0 Reaction = 5 | Molecule = 0 Enzyme = 0 Reaction = 0 | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/ 2001-12-12 00:00:00 | |||||||||||||
| Related Pathway: 16, 29, 205, 219, 238, 248, 261, 267, 276, 285, 325, 342, 360 | |||||||||||||||||||
| Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) | |||||||||||||||||||
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| 4 | PP2B Pathway No. 205 | CaMKII_2003 Accession No. 49 | Network | Molecule = 5 Enzyme = 0 Reaction = 5 | Molecule = 0 Enzyme = 0 Reaction = 0 | Bhalla US. Biophys J. 2004 Aug;87(2):733-44. ( peer-reviewed publication )./ 2003-04-28 00:00:00 | |||||||||||||
| Related Pathway: 16, 29, 83, 219, 238, 248, 261, 267, 276, 285, 325, 342, 360 | |||||||||||||||||||
| Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) | |||||||||||||||||||
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| 5 | PP2B Pathway No. 219 | MAPK_network_ 2003 Accession No. 50 | Network | Molecule = 5 Enzyme = 0 Reaction = 5 | Molecule = 0 Enzyme = 0 Reaction = 0 | Bhalla US Biophys J. 2004 Aug;87(2):745-53. ( peer-reviewed publication )/ 2003-04-28 00:00:00 | |||||||||||||
| Related Pathway: 16, 29, 83, 205, 238, 248, 261, 267, 276, 285, 325, 342, 360 | |||||||||||||||||||
| Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) | |||||||||||||||||||
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| 6 | PP2B Pathway No. 238 | AMPAR_traff_ model0 Accession No. 59 | Network | Molecule = 4 Enzyme = 40 Reaction = 3 | Molecule = 0 Enzyme = 1 Reaction = 0 | Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/ 2005-07-19 00:00:00 | |||||||||||||
| Related Pathway: 16, 29, 83, 205, 219, 248, 261, 267, 276, 285, 325, 342, 360 | |||||||||||||||||||
| Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) | |||||||||||||||||||
| 7 | PP2B Pathway No. 248 | AMPAR_traff_ model1 Accession No. 60 | Network | Molecule = 4 Enzyme = 40 Reaction = 3 | Molecule = 0 Enzyme = 1 Reaction = 0 | Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/ 2005-07-19 00:00:00 | |||||||||||||
| Related Pathway: 16, 29, 83, 205, 219, 238, 261, 267, 276, 285, 325, 342, 360 | |||||||||||||||||||
| Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) | |||||||||||||||||||
| 8 | PP2B Pathway No. 261 | CaMKII_noPKA_ model3 Accession No. 62 | Network | Molecule = 2 Enzyme = 0 Reaction = 3 | Molecule = 0 Enzyme = 0 Reaction = 0 | Hayer A, Bhalla US PLoS PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/ 2005-07-19 00:00:00 | |||||||||||||
| Related Pathway: 16, 29, 83, 205, 219, 238, 248, 267, 276, 285, 325, 342, 360 | |||||||||||||||||||
| Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) | |||||||||||||||||||
| 9 | PP2B Pathway No. 267 | CaMKII_model3 Accession No. 63 | Network | Molecule = 2 Enzyme = 0 Reaction = 3 | Molecule = 0 Enzyme = 0 Reaction = 0 | Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/ 2005-07-19 00:00:00 | |||||||||||||
| Related Pathway: 16, 29, 83, 205, 219, 238, 248, 261, 276, 285, 325, 342, 360 | |||||||||||||||||||
| Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) | |||||||||||||||||||
| 10 | PP2B Pathway No. 276 | AMPAR_CaMKII_ strong_coupling Accession No. 64 | Network | Molecule = 2 Enzyme = 0 Reaction = 3 | Molecule = 0 Enzyme = 0 Reaction = 0 | Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/ 2005-07-19 00:00:00 | |||||||||||||
| Related Pathway: 16, 29, 83, 205, 219, 238, 248, 261, 267, 285, 325, 342, 360 | |||||||||||||||||||
| Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) | |||||||||||||||||||
| 11 | PP2B Pathway No. 285 | AMPAR_CaMKII_ weak_coupling Accession No. 65 | Network | Molecule = 4 Enzyme = 40 Reaction = 3 | Molecule = 0 Enzyme = 1 Reaction = 0 | Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/ 2005-07-21 00:00:00 | |||||||||||||
| Related Pathway: 16, 29, 83, 205, 219, 238, 248, 261, 267, 276, 325, 342, 360 | |||||||||||||||||||
| Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) | |||||||||||||||||||
| 12 | PP2B Pathway No. 325 | Ajay_Bhalla_ 2004_PKM_Tuning Accession No. 76 | Network | Molecule = 5 Enzyme = 0 Reaction = 5 | Molecule = 0 Enzyme = 0 Reaction = 0 | Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/ 2006-12-12 00:00:00 | |||||||||||||
| Related Pathway: 16, 29, 83, 205, 219, 238, 248, 261, 267, 276, 285, 342, 360 | |||||||||||||||||||
| Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) | |||||||||||||||||||
| 13 | PP2B Pathway No. 342 | Ajay_Bhalla_ 2004_PKM_MKP3_ Tuning Accession No. 77 | Network | Molecule = 5 Enzyme = 0 Reaction = 5 | Molecule = 0 Enzyme = 0 Reaction = 0 | Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80 ( Peer-reviewed publication )/ 2006-12-12 00:00:00 | |||||||||||||
| Related Pathway: 16, 29, 83, 205, 219, 238, 248, 261, 267, 276, 285, 325, 360 | |||||||||||||||||||
| Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) | |||||||||||||||||||
| 14 | PP2B Pathway No. 360 | Ajay_Bhalla_ 2004_Feedback_ Tuning Accession No. 78 | Network | Molecule = 5 Enzyme = 0 Reaction = 5 | Molecule = 0 Enzyme = 0 Reaction = 0 | Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/ 2006-12-12 00:00:00 | |||||||||||||
| Related Pathway: 16, 29, 83, 205, 219, 238, 248, 261, 267, 276, 285, 325, 342 | |||||||||||||||||||
| Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) | |||||||||||||||||||
indicates that ordering is done according to ascending or descending order.
or Pathway 