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Pathway Name Pathway No. | Accession Name Accession No. | Accession Type | Pathway statistics | plc_g statistics | Source Entry Date |
1 | PLC_g Pathway No. 10 | fig2_egfr
Accession No. 1 | Network | Molecule = 4 Enzyme = 2 Reaction = 3
| Molecule = 1 Enzyme = 0 Reaction = 0
| Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/ 2001-11-07 00:00:00 |
| #6Related Pathway: 79, 215, 321, 338, 356 |
| This network was used to generate figure 2 in Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It consists of the MAPK cascade in a feedback loop with PKC, and receives input from the EGFR in the synapse. Demonstration script files for generating the figures in the paper, including figure 2, are available here. |
| This pathway is part of accession 1 and is completely specified in the file acc1.g. There is no separate files for just this pathway. |
Format | File | Native Format (GENESIS format) | acc1.g | GENESIS Format (Annotated version) | Anno_acc1.g |
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2 | PLC_g Pathway No. 79 | Synaptic_ Network Accession No. 16 | Network | Molecule = 4 Enzyme = 2 Reaction = 3
| Molecule = 1 Enzyme = 0 Reaction = 0
| Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/ 2001-12-12 00:00:00 |
| #6Related Pathway: 10, 215, 321, 338, 356 |
| This group represents phospholipase C -gamma. Originally PLC-II. Ryu et al JBC 262(26) 12511-12518 1987. Homma et al Biochem J 269:13-18 is also a good source of early info. |
| This pathway is part of accession 16 and is completely specified in the file acc16.g. There is no separate files for just this pathway. |
Format | File | Native Format (GENESIS format) | acc16.g | GENESIS Format (Annotated version) | Anno_acc16.g |
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3 | PLC_g Pathway No. 215 | MAPK_network_ 2003 Accession No. 50 | Network | Molecule = 4 Enzyme = 2 Reaction = 3
| Molecule = 1 Enzyme = 0 Reaction = 0
| Bhalla US Biophys J. 2004 Aug;87(2):745-53. ( peer-reviewed publication )/ 2003-04-28 00:00:00 |
| #6Related Pathway: 10, 79, 321, 338, 356 |
| This is a network model of many pathways present at the neuronal synapse. The network has properties of temporal tuning as well as steady-state computational properties. In its default form the network is bistable.Bhalla US Biophys J. 2004 Aug;87(2):745-53 |
| This pathway is part of accession 50 and is completely specified in the file acc50.g. There is no separate files for just this pathway. |
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4 | PLC_g Pathway No. 321 | Ajay_Bhalla_ 2004_PKM_Tuning Accession No. 76 | Network | Molecule = 4 Enzyme = 2 Reaction = 3
| Molecule = 1 Enzyme = 0 Reaction = 0
| Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/ 2006-12-12 00:00:00 |
| #6Related Pathway: 10, 79, 215, 338, 356 |
| This model is taken from the Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. This is the reference feedforward model from Figure 8a. |
| This pathway is part of accession 76 and is completely specified in the file acc76.g. There is no separate files for just this pathway. |
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5 | PLC_g Pathway No. 338 | Ajay_Bhalla_ 2004_PKM_MKP3_ Tuning Accession No. 77 | Network | Molecule = 4 Enzyme = 2 Reaction = 3
| Molecule = 1 Enzyme = 0 Reaction = 0
| Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80 ( Peer-reviewed publication )/ 2006-12-12 00:00:00 |
| #6Related Pathway: 10, 79, 215, 321, 356 |
| This model is based on Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. This is the feedforward model with MPK3 from figure 8a. |
| This pathway is part of accession 77 and is completely specified in the file acc77.g. There is no separate files for just this pathway. |
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6 | PLC_g Pathway No. 356 | Ajay_Bhalla_ 2004_Feedback_ Tuning Accession No. 78 | Network | Molecule = 4 Enzyme = 2 Reaction = 3
| Molecule = 1 Enzyme = 0 Reaction = 0
| Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/ 2006-12-12 00:00:00 |
| #6Related Pathway: 10, 79, 215, 321, 338 |
| This model is taken from Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. This is the feedback model from Figure 8a. |
| This pathway is part of accession 78 and is completely specified in the file acc78.g. There is no separate files for just this pathway. |
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