| |
Pathway Name
Pathway No. | Accession Name
Accession No. | Accession
Type | Pathway statistics | pp2b statistics | Source
Entry Date |
| 1 | PP2B
Pathway No. 16 | fig3_CaMKII
Accession No. 2 | Network | Molecule = 5
Enzyme = 0
Reaction = 5
| Molecule = 0
Enzyme = 0
Reaction = 0
| Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/
2001-11-07 00:00:00 |
| | #14Related Pathway:
29, 83, 205, 219, 238, 248, 261, 267, 276, 285, 325, 342, 360 |
| | This is the model file for figure 3 from Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It is a model of the Ca activation of CaMKII and other CaM-activated enzymes. It includes the regulatory phosphatases PP1 and PP2B (Calcineurin) acting on CaMKII and also includes CaM-activated adenylyl cyclase and PKA in the synapse.
Demonstration script files for generating the figures in the paper, including figure 3, are available here. |
| | This pathway is part of accession 2 and is completely specified in the file acc2.g.
There is no separate files for just this pathway. |
| Format | File | | Native Format (GENESIS format) | acc2.g | | GENESIS Format (Annotated version) | Anno_acc2.g |
|
| 2 | PP2B
Pathway No. 29 | fig4_synapse
Accession No. 3 | Network | Molecule = 5
Enzyme = 0
Reaction = 5
| Molecule = 0
Enzyme = 0
Reaction = 0
| Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/
2001-11-07 00:00:00 |
| | #14Related Pathway:
16, 83, 205, 219, 238, 248, 261, 267, 276, 285, 325, 342, 360 |
| | This is the composite model of 4 kinases: PKC, MAPK, PKA and CaMKII and numerous regulatory pathways involved in synaptic signaling. From Bhalla US and Iyengar R. Science (1999) 283(5400):381-7.This model comes from figure 4 of that paper.
Demonstration script files for generating the figures in the paper, including figure 4, are available here. |
| | This pathway is part of accession 3 and is completely specified in the file acc3.g.
There is no separate files for just this pathway. |
| Format | File | | Native Format (GENESIS format) | acc3.g | | GENESIS Format (Annotated version) | Anno_acc3.g |
|
| 3 | PP2B
Pathway No. 325 | Ajay_Bhalla_
2004_PKM_Tuning
Accession No. 76 | Network | Molecule = 5
Enzyme = 0
Reaction = 5
| Molecule = 0
Enzyme = 0
Reaction = 0
| Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/
2006-12-12 00:00:00 |
| | #14Related Pathway:
16, 29, 83, 205, 219, 238, 248, 261, 267, 276, 285, 342, 360 |
| | Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) |
| | This pathway is part of accession 76 and is completely specified in the file acc76.g.
There is no separate files for just this pathway. |
|
| 4 | PP2B
Pathway No. 360 | Ajay_Bhalla_
2004_Feedback_
Tuning
Accession No. 78 | Network | Molecule = 5
Enzyme = 0
Reaction = 5
| Molecule = 0
Enzyme = 0
Reaction = 0
| Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/
2006-12-12 00:00:00 |
| | #14Related Pathway:
16, 29, 83, 205, 219, 238, 248, 261, 267, 276, 285, 325, 342 |
| | Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) |
| | This pathway is part of accession 78 and is completely specified in the file acc78.g.
There is no separate files for just this pathway. |
|
| 5 | PP2B
Pathway No. 342 | Ajay_Bhalla_
2004_PKM_MKP3_
Tuning
Accession No. 77 | Network | Molecule = 5
Enzyme = 0
Reaction = 5
| Molecule = 0
Enzyme = 0
Reaction = 0
| Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80 ( Peer-reviewed publication )/
2006-12-12 00:00:00 |
| | #14Related Pathway:
16, 29, 83, 205, 219, 238, 248, 261, 267, 276, 285, 325, 360 |
| | Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) |
| | This pathway is part of accession 77 and is completely specified in the file acc77.g.
There is no separate files for just this pathway. |
|
| 6 | PP2B
Pathway No. 83 | Synaptic_
Network
Accession No. 16 | Network | Molecule = 5
Enzyme = 0
Reaction = 5
| Molecule = 0
Enzyme = 0
Reaction = 0
| Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/
2001-12-12 00:00:00 |
| | #14Related Pathway:
16, 29, 205, 219, 238, 248, 261, 267, 276, 285, 325, 342, 360 |
| | Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) |
| | This pathway is part of accession 16 and is completely specified in the file acc16.g.
There is no separate files for just this pathway. |
| Format | File | | Native Format (GENESIS format) | acc16.g | | GENESIS Format (Annotated version) | Anno_acc16.g |
|
| 7 | PP2B
Pathway No. 219 | MAPK_network_
2003
Accession No. 50 | Network | Molecule = 5
Enzyme = 0
Reaction = 5
| Molecule = 0
Enzyme = 0
Reaction = 0
| Bhalla US Biophys J. 2004 Aug;87(2):745-53. ( peer-reviewed publication )/
2003-04-28 00:00:00 |
| | #14Related Pathway:
16, 29, 83, 205, 238, 248, 261, 267, 276, 285, 325, 342, 360 |
| | Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) |
| | This pathway is part of accession 50 and is completely specified in the file acc50.g.
There is no separate files for just this pathway. |
|
| 8 | PP2B
Pathway No. 205 | CaMKII_2003
Accession No. 49 | Network | Molecule = 5
Enzyme = 0
Reaction = 5
| Molecule = 0
Enzyme = 0
Reaction = 0
| Bhalla US. Biophys J. 2004 Aug;87(2):733-44. ( peer-reviewed publication )./
2003-04-28 00:00:00 |
| | #14Related Pathway:
16, 29, 83, 219, 238, 248, 261, 267, 276, 285, 325, 342, 360 |
| | Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) |
| | This pathway is part of accession 49 and is completely specified in the file acc49.g.
There is no separate files for just this pathway. |
|
| 9 | PP2B
Pathway No. 261 | CaMKII_noPKA_
model3
Accession No. 62 | Network | Molecule = 2
Enzyme = 0
Reaction = 3
| Molecule = 0
Enzyme = 0
Reaction = 0
| Hayer A, Bhalla US PLoS PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
2005-07-19 00:00:00 |
| | #14Related Pathway:
16, 29, 83, 205, 219, 238, 248, 267, 276, 285, 325, 342, 360 |
| | Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) |
| | This pathway is part of accession 62 and is completely specified in the file acc62.g.
There is no separate files for just this pathway. |
|
| 10 | PP2B
Pathway No. 238 | AMPAR_traff_
model0
Accession No. 59 | Network | Molecule = 4
Enzyme = 40
Reaction = 3
| Molecule = 0
Enzyme = 1
Reaction = 0
| Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
2005-07-19 00:00:00 |
| | #14Related Pathway:
16, 29, 83, 205, 219, 248, 261, 267, 276, 285, 325, 342, 360 |
| | Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) |
| | This pathway is part of accession 59 and is completely specified in the file acc59.g.
There is no separate files for just this pathway. |
|
| 11 | PP2B
Pathway No. 248 | AMPAR_traff_
model1
Accession No. 60 | Network | Molecule = 4
Enzyme = 40
Reaction = 3
| Molecule = 0
Enzyme = 1
Reaction = 0
| Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
2005-07-19 00:00:00 |
| | #14Related Pathway:
16, 29, 83, 205, 219, 238, 261, 267, 276, 285, 325, 342, 360 |
| | Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) |
| | This pathway is part of accession 60 and is completely specified in the file acc60.g.
There is no separate files for just this pathway. |
|
| 12 | PP2B
Pathway No. 267 | CaMKII_model3
Accession No. 63 | Network | Molecule = 2
Enzyme = 0
Reaction = 3
| Molecule = 0
Enzyme = 0
Reaction = 0
| Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
2005-07-19 00:00:00 |
| | #14Related Pathway:
16, 29, 83, 205, 219, 238, 248, 261, 276, 285, 325, 342, 360 |
| | Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) |
| | This pathway is part of accession 63 and is completely specified in the file acc63.g.
There is no separate files for just this pathway. |
|
| 13 | PP2B
Pathway No. 276 | AMPAR_CaMKII_
strong_coupling
Accession No. 64 | Network | Molecule = 2
Enzyme = 0
Reaction = 3
| Molecule = 0
Enzyme = 0
Reaction = 0
| Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
2005-07-19 00:00:00 |
| | #14Related Pathway:
16, 29, 83, 205, 219, 238, 248, 261, 267, 285, 325, 342, 360 |
| | Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) |
| | This pathway is part of accession 64 and is completely specified in the file acc64.g.
There is no separate files for just this pathway. |
|
| 14 | PP2B
Pathway No. 285 | AMPAR_CaMKII_
weak_coupling
Accession No. 65 | Network | Molecule = 4
Enzyme = 40
Reaction = 3
| Molecule = 0
Enzyme = 1
Reaction = 0
| Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
2005-07-21 00:00:00 |
| | #14Related Pathway:
16, 29, 83, 205, 219, 238, 248, 261, 267, 276, 325, 342, 360 |
| | Also called Calcineurin. Major sources of info: Cohen, P Ann Rev Biochem 1989 58:453-508 Mumby and Walker Physiol Rev 73:4 673-699 Stemmer and Klee Biochem 33 1994 6859-6866 Liu and Storm JBC 264:22 1989 12800-12804 This model is unusual: There is actually more expt info than I want to put in the model at this time. Phosph: Hashimoto and Soderling JBC 1989 264:28 16624-16629 (Not used) |
| | This pathway is part of accession 65 and is completely specified in the file acc65.g.
There is no separate files for just this pathway. |
|
or Pathway 