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Result: 1 - 20 of 54 rows are displayed Previous of 3  Next

Reaction List for CamKII

Entries are grouped according to Reaction Name and they are alternately color coded using  and  color.
Further ordering can be done to the table header.  indicates that ordering is done according to ascending or descending order.
Keq is calculated only for first order reactions.
Kd is calculated only for second order reactions. [nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules]
  Reaction
Name		Accession Name / 
Accession No.		Pathway Name / 
Pathway No.		KfKbKdtauReagents
1 CaMKII-bind-CaMfig3_CaMKII

Accession No. 2		CaMKII

Pathway No. 13		49.9998
(uM^-1 s^-1)		5
(s^-1)		Kd(bf) = 0.1(uM)-  Substrate:
 CaM-Ca4
 CaMKII

 Products:
 CaMKII-CaM
2 CaMKII-bind-CaMfig4_synapse

Accession No. 3		CaMKII

Pathway No. 26		49.9998
(uM^-1 s^-1)		5
(s^-1)		Kd(bf) = 0.1(uM)-  Substrate:
 CaM-Ca4
 CaMKII

 Products:
 CaMKII-CaM
3 CaMKII-bind-CaM
  • Synaptic_
    Network
    Accession No. 16
    		• CaMKII

    Pathway No. 80    		49.9998
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kd = 0.1 uM. Rate is fast (see Hanson et al Neuron 12 943-956 1994) Hanson and Schulman 1992 AnnRev Biochem 61:559-601 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    4 CaMKII-bind-CaM
  • NonOsc_Ca_
    IP3metabolism
    Accession No. 23
    		• CaMKII

    Pathway No. 106    		49.9998
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kd = 0.1 uM. Rate is fast (see Hanson et al Neuron 12 943-956 1994) Hanson and Schulman 1992 AnnRev Biochem 61:559-601 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    5 CaMKII-bind-CaM
  • Osc_Ca_
    IP3metabolism
    Accession No. 24
    		• CaMKII

    Pathway No. 121    		49.9998
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kd = 0.1 uM. Rate is fast (see Hanson et al Neuron 12 943-956 1994) Hanson and Schulman 1992 AnnRev Biochem 61:559-601 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    6 CaMKII-bind-CaM
  • NonOsc_Ca_
    IP3metabolism
    Accession No. 31
    		• CaMKII

    Pathway No. 145    		49.9998
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kd = 0.1 uM. Rate is fast (see Hanson et al Neuron 12 943-956 1994) Hanson and Schulman 1992 AnnRev Biochem 61:559-601 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    7 CaMKII-bind-CaM
  • Osc_Ca_
    IP3metabolism
    Accession No. 32
    		• CaMKII

    Pathway No. 159    		49.9998
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kd = 0.1 uM. Rate is fast (see Hanson et al Neuron 12 943-956 1994) Hanson and Schulman 1992 AnnRev Biochem 61:559-601 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    8 CaMKII-bind-CaMCaMKII

    Accession No. 33    		CaMKII

    Pathway No. 174    		0.2
    (uM^-1 s^-1)    		2700
    (s^-1)    		Kd(bf) = 13500(uM)-  Substrate:
     CaM
     CaMKII

     Products:
     CaMKII-CaM
    9 CaMKII-bind-CaMCaMKII_2003

    Accession No. 49    		CaMKII

    Pathway No. 202    		49.9998
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kb/Kf = 6e4 #/cell. Rate is fast (see Hanson et al Neuron 12 943-956 1994) so lets say kb = 10. This gives kf = 1.6667e-4 H&S AnnRev Biochem 92 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    10 CaMKII-bind-CaM
  • MAPK_network_
    2003
    Accession No. 50
    		• CaMKII

    Pathway No. 216    		49.9998
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kb/Kf = 6e4 #/cell. Rate is fast (see Hanson et al Neuron 12 943-956 1994) so lets say kb = 10. This gives kf = 1.6667e-4 H&S AnnRev Biochem 92 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    11 CaMKII-bind-CaM
  • AMPAR_traff_
    model0
    Accession No. 59
    		• CaMKII

    Pathway No. 235    		49.9997
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kb/Kf = 6e4 #/cell. Rate is fast (see Hanson et al Neuron 12 943-956 1994) so lets say kb = 10. This gives kf = 1.6667e-4 H&S AnnRev Biochem 92 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    12 CaMKII-bind-CaM
  • AMPAR_traff_
    model1
    Accession No. 60
    		• CaMKII

    Pathway No. 245    		49.9997
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kb/Kf = 6e4 #/cell. Rate is fast (see Hanson et al Neuron 12 943-956 1994) so lets say kb = 10. This gives kf = 1.6667e-4 H&S AnnRev Biochem 92 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    13 CaMKII-bind-CaM
  • CaMKII_noPKA_
    model3
    Accession No. 62
    		• CaMKII

    Pathway No. 258    		49.9997
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kb/Kf = 6e4 #/cell. Rate is fast (see Hanson et al Neuron 12 943-956 1994) so lets say kb = 10. This gives kf = 1.6667e-4 H&S AnnRev Biochem 92 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    14 CaMKII-bind-CaMCaMKII_model3

    Accession No. 63    		CaMKII

    Pathway No. 264    		49.9997
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kb/Kf = 6e4 #/cell. Rate is fast (see Hanson et al Neuron 12 943-956 1994) so lets say kb = 10. This gives kf = 1.6667e-4 H&S AnnRev Biochem 92 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    15 CaMKII-bind-CaM
  • AMPAR_CaMKII_
    strong_coupling
    Accession No. 64
    		• CaMKII

    Pathway No. 272    		49.9997
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kb/Kf = 6e4 #/cell. Rate is fast (see Hanson et al Neuron 12 943-956 1994) so lets say kb = 10. This gives kf = 1.6667e-4 H&S AnnRev Biochem 92 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    16 CaMKII-bind-CaM
  • AMPAR_CaMKII_
    weak_coupling
    Accession No. 65
    		• CaMKII

    Pathway No. 282    		49.9997
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kb/Kf = 6e4 #/cell. Rate is fast (see Hanson et al Neuron 12 943-956 1994) so lets say kb = 10. This gives kf = 1.6667e-4 H&S AnnRev Biochem 92 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    17 CaMKII-bind-CaM
  • Ajay_Bhalla_
    2004_PKM_Tuning
    Accession No. 76
    		• CaMKII

    Pathway No. 322    		49.9995
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kb/Kf = 6e4 #/cell. Rate is fast (see Hanson et al Neuron 12 943-956 1994) so lets say kb = 10. This gives kf = 1.6667e-4 H&S AnnRev Biochem 92 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    18 CaMKII-bind-CaM
  • Ajay_Bhalla_
    2004_PKM_MKP3_
    Tuning
    Accession No. 77
    		• CaMKII

    Pathway No. 339    		49.9995
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kb/Kf = 6e4 #/cell. Rate is fast (see Hanson et al Neuron 12 943-956 1994) so lets say kb = 10. This gives kf = 1.6667e-4 H&S AnnRev Biochem 92 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    19 CaMKII-bind-CaM
  • Ajay_Bhalla_
    2004_Feedback_
    Tuning
    Accession No. 78
    		• CaMKII

    Pathway No. 357    		49.9995
    (uM^-1 s^-1)    		5
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     CaM-Ca4
     CaMKII

     Products:
     CaMKII-CaM
      This is tricky. There is some cooperativity here arising from interactions between the subunits of the CAMKII holoenzyme. However, the stoichiometry is 1. Kb/Kf = 6e4 #/cell. Rate is fast (see Hanson et al Neuron 12 943-956 1994) so lets say kb = 10. This gives kf = 1.6667e-4 H&S AnnRev Biochem 92 give tau for dissoc as 0.2 sec at low Ca, 0.4 at high. Low Ca = 100 nM = physiol.
    20 
  • CaMKII-bind-CaM-
    PSD
  • AMPAR_traff_
    model0
    Accession No. 59
    		• CaMKII

    Pathway No. 235    		49.9998
    (uM^-1 s^-1)    		0
    (s^-1)    		--  Substrate:
     CaMKII-PSD
     CaM-Ca4-PSD

     Products:
     CaMKII-CaM-PSD
     
    Result: 1 - 20 of 54 rows are displayed Previous of 3  Next


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