Accession Name | Accession No. | Accession Type | Pathway Link |
Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 | 81 | Network | Shared_Object_Ajay_bhalla_2007_ReacDiff1_1e-12, PKC, MAPK, Ras, CaM, PKM, chain, kinetics, PKC, MAPK, Ras, CaM, PKM, kinetics[1], PKC, MAPK, Ras, CaM, PKM, kinetics[2], PKC, MAPK, Ras, CaM, PKM, kinetics[3], PKC, MAPK, MAPK, Ras, CaM, PKM, kinetics[4], PKC, MAPK, Ras, CaM, PKM, kinetics[5], PKC, MAPK, Ras, kinetics[6], CaM, PKM, PKC, MAPK, Ras, CaM, PKM, kinetics[7], PKC, Ras, CaM, PKM, kinetics[8], PKC, MAPK, Ras, CaM, PKM, kinetics[9], PKC, MAPK, Ras, CaM, PKM, kinetics[10], PKC, MAPK, Ras, CaM, PKM, kinetics[11], PKC, MAPK, Ras, CaM, PKM, kinetics[12], PKC, MAPK, Ras, CaM, PKM, kinetics[13], PKC, MAPK, Ras, CaM, PKM, kinetics[14], PKC, MAPK, Ras, CaM, PKM, kinetics[15], PKC, MAPK, Ras, CaM, PKM, kinetics[16], PKC, MAPK, Ras, CaM, PKM, kinetics[17], PKC, MAPK, Ras, CaM, PKM, kinetics[18], PKC, MAPK, Ras, CaM, PKM, kinetics[19], PKC, MAPK, Ras, CaM, PKM, kinetics[20], PKC, MAPK, Ras, CaM, PKM, kinetics[21], PKC, MAPK, Ras, CaM, PKM, kinetics[22], PKC, MAPK, Ras, CaM, PKM, kinetics[23], PKC, MAPK, Ras, CaM, PKM |
This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-12_Fig4A which was used for the model to replicate Figure 4A from the paper.
This stimulus file pkm_mapk22_diff_1e-12_Fig4G which was used for the model to replicate Figure 4G from the paper |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
1 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 378 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
2 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
3 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 380 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
4 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 385 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
5 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
6 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 387 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
7 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 391 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
8 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
9 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 393 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
10 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 397 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
11 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
12 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 399 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
13 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 404 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
14 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
15 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 406 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
16 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 410 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
17 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
18 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 412 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
19 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 416 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
20 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
21 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 419 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
22 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 422 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
23 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
24 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 424 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
25 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 427 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
26 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
27 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 429 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
28 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 433 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
29 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
30 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 435 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
31 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 439 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
32 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
33 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 441 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
34 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 445 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
35 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
36 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 447 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
37 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 451 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
38 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
39 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 453 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
40 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 457 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
41 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
42 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 459 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
43 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 463 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
44 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
45 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 465 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
46 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 469 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
47 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
48 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 471 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
49 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 475 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
50 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
51 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 477 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
52 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 481 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
53 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
54 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 483 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
55 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 487 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
56 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
57 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 489 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
58 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 493 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
59 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
60 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 495 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
61 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 499 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
62 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
63 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 501 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
64 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 505 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
65 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
66 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 507 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
67 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 511 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
68 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
69 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 513 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
70 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 517 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
71 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
72 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 519 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
73 | CaM-bind-GEF | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Ras Pathway No. : 523 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
|
| We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
74 | trigger_PKM | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKM Pathway No. : 525 | 9.9998 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.1(uM) | - | Substrate CaM-Ca4 Ca_detector
Product Ca.detector_ complex
|
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
1 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 379 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
2 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
3 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 386 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
4 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
5 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 392 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
6 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
7 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 398 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
8 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
9 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 405 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
10 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
11 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 411 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
12 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
13 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 418 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
14 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
15 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 423 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
16 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
17 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 428 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
18 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
19 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 434 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
20 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
21 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 440 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
22 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
23 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 446 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
24 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
25 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 452 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
26 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
27 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 458 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
28 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
29 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 464 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
30 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
31 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 470 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
32 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
33 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 476 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
34 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
35 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 482 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
36 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
37 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 488 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
38 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
39 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 494 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
40 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
41 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 500 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
42 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
43 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 506 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
44 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
45 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 512 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
46 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
47 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 518 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |
48 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate CaM-Ca4
Product CaM-Ca4
|
49 | CaM-Ca3-bind-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | CaM Pathway No. : 524 | 0.465 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 21.5051(uM) | - | Substrate Ca CaM-Ca3
Product CaM-Ca4
|
| Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 * 6e5 so kf = 7.75e-7, kb = 10 |