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Accession Type:
Network
Ajay_Bhalla_
2007_ReacDiff3
Shared_Object_
Ajay_Bhalla_
2007_ReacDiff3
 Molecule
 Enzyme
 Reaction
PKC
PLA2
MAPK
PLA2
Ras
CaM
chain
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3
PKC
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[1]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[2]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[3]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[4]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[5]
PKC
PLA2
MAPK
Ras
MAPK
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[6]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[7]
PKC
PLA2
MAPK
Ras
CaM
PKC
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[8]
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[9]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[10]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[11]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[12]
PKC
PLA2
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[13]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[14]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[15]
PKC
PLA2
MAPK
Ras
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[16]
CaM
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[17]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[18]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[19]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[20]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[21]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[22]
PKC
PLA2
MAPK
Ras
CaM
Shared Object_
Ajay_Bhalla_
2007_ReacDiff3_
[23]
PKC
PLA2
MAPK
Ras
CaM

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Reaction List for pathway Shared_Object_Ajay_Bhalla_2007_ReacDiff3 (Pathway Number 918)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 Ca_diff2
(s^-1)		2
(s^-1)		Keq = 1(uM)0.25secCa_input
Ca
2 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
3 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
4 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
5 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
6 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
7 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
8 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
9 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
10 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
11 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
12 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
13 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
14 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
15 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
16 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
17 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
18 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
19 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
20 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
21 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
22 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
23 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
24 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
25 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
26 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
27 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
28 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
29 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
30 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
31 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
32 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
33 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
34 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
35 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
36 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
37 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
38 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
39 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
40 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
41 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
42 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
43 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
44 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
45 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
46 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
47 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
48 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
49 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
50 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
51 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
52 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
53 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
54 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
55 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
56 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
57 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
58 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
59 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
60 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
61 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
62 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
63 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
64 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
65 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
66 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
67 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
68 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
69 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
70 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
71 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
72 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
73 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
74 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
75 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
76 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
77 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
78 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
79 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
80 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
81 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
82 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
83 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
84 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
85 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
86 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
87 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
88 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
89 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
90 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
91 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
92 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
93 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
94 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
95 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
96 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
97 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
98 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
99 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
100 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
101 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
102 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
103 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
104 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
105 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
106 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
107 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
108 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
109 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
110 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
111 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
112 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
113 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
114 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
115 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
116 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
117 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
118 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
119 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
120 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
121 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
122 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
123 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
124 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
125 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
126 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
127 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
128 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
129 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
130 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
131 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
132 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
133 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
134 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
135 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
136 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
137 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
138 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
139 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
140 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
141 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
142 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
143 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
144 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
145 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
146 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
147 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
148 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
149 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
150 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
151 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
152 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
153 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
154 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
155 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
156 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
157 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
158 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
159 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
160 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
161 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
162 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
163 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
164 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
165 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
166 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
167 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
168 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
169 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
170 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
171 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
172 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
173 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
174 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
175 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
176 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
177 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
178 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
179 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
180 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
181 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
182 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
183 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
184 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
185 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
186 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
187 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
188 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
189 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
190 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
191 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
192 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
193 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
194 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
195 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
196 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
197 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
198 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
199 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
200 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
201 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
202 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
203 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
204 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
205 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
206 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
207 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
208 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
209 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
210 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
211 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
212 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
213 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
214 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
215 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
216 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
217 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
218 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
219 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
220 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
221 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
222 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
223 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
224 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
225 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
226 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
227 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
228 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
229 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
230 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
231 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
232 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
233 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
234 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
235 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
236 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
237 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
238 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
239 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
240 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
241 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
242 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
243 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
244 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
245 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
246 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
247 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
248 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
249 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
250 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
251 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
252 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
253 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
254 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
255 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
256 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
257 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
258 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
259 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
260 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
261 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
262 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
263 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
264 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
265 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
266 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
267 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
268 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
269 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
270 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
271 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
272 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
273 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
274 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
275 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
276 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
277 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
278 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
279 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
280 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
281 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
282 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
283 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
284 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
285 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
286 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
287 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
288 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
289 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
290 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
291 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
292 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
293 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
294 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
295 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
296 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
297 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
298 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
299 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
300 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
301 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
302 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
303 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
304 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
305 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
306 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
307 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
308 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
309 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
310 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
311 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
312 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
313 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
314 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
315 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
316 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
317 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
318 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
319 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
320 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
321 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
322 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
323 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
324 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
325 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
326 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
327 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
328 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
329 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
330 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
331 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
332 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
333 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
334 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
335 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
336 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
337 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
338 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
339 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
340 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
341 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
342 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
343 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
344 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
345 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
346 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
347 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
348 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
349 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
350 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
351 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
352 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
353 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
354 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
355 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
356 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
357 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
358 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
359 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
360 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
361 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
362 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
363 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
364 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
365 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
366 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
367 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
368 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
369 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
370 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
371 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
372 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
373 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
374 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
375 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
376 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
377 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
378 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
379 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
380 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
381 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
382 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
383 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
384 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
385 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
386 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
387 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
388 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
389 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
390 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
391 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
392 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
393 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
394 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
395 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
396 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
397 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
398 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
399 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
400 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
401 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
402 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
403 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
404 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
405 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
406 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
407 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
408 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
409 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
410 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
411 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
412 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
413 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
414 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
415 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
416 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
417 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
418 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
419 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
420 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
421 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
422 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
423 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
424 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
425 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
426 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
427 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
428 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
429 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
430 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
431 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
432 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
433 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
434 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
435 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
436 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
437 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
438 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
439 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
440 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
441 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
442 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
443 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
444 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
445 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
446 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
447 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
448 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
449 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
450 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
451 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
452 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
453 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
454 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
455 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
456 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
457 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
458 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
459 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
460 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
461 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
462 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
463 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
464 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
465 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
466 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
467 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
468 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
469 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
470 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
471 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
472 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
473 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
474 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
475 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
476 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
477 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
478 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
479 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
480 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
481 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
482 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
483 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
484 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
485 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
486 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
487 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
488 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
489 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
490 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
491 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
492 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
493 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
494 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
495 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
496 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
497 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
498 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
499 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
500 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
501 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
502 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
503 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
504 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
505 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
506 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
507 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
508 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
509 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
510 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
511 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
512 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
513 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
514 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
515 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
516 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
517 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
518 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
519 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
520 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
521 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
522 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
523 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
524 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
525 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
526 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
527 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
528 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
529 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
530 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
531 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
532 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
533 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
534 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
535 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
536 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
537 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
538 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
539 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
540 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
541 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
542 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
543 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
544 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
545 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
546 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
547 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
548 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
549 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
550 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
551 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
552 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
553 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
554 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
555 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
556 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
557 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
558 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
559 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
560 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
561 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
562 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
563 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
564 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
565 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
566 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
567 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
568 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
569 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
570 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
571 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
572 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
573 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
574 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
575 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
576 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
577 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
578 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
579 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
580 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
581 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
582 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
583 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
584 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
585 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
586 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
587 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
588 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
589 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
590 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
591 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
592 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
593 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
594 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
595 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
596 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
597 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
598 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
599 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
600 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
601 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
602 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
603 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
604 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
605 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
606 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
607 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
608 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
609 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
610 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
611 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
612 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
613 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
614 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
615 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
616 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
617 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
618 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
619 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
620 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
621 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
622 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
623 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
624 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
625 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
626 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
627 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
628 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
629 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
630 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
631 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
632 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
633 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
634 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
635 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
636 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
637 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
638 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
639 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
640 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
641 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
642 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
643 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
644 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
645 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
646 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
647 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
648 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
649 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
650 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
651 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
652 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
653 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
654 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
655 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
656 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
657 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
658 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
659 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
660 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
661 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
662 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
663 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
664 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
665 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
666 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
667 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
668 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
669 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
670 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
671 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
672 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
673 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
674 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
675 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
676 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
677 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
678 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
679 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
680 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
681 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
682 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
683 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
684 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
685 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
686 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
687 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
688 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
689 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
690 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
691 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
692 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
693 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
694 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
695 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
696 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
697 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
698 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
699 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
700 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
701 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
702 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
703 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
704 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
705 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
706 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
707 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
708 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
709 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
710 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
711 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
712 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
713 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
714 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
715 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
716 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
717 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
718 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
719 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
720 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
721 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
722 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
723 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
724 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
725 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
726 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
727 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
728 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
729 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
730 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
731 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
732 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
733 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
734 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
735 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
736 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
737 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
738 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
739 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
740 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
741 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
742 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
743 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
744 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
745 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
746 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
747 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
748 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
749 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
750 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
751 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
752 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
753 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
754 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
755 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
756 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
757 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
758 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
759 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
760 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
761 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca
PKC-Ca
762 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA*
PKC-DAG-AA*
763 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-AA*
PKC-Ca-AA*
764 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-memb*
PKC-Ca-memb*
765 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-memb*
PKC-DAG-memb*
766 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-basal*
PKC-basal*
767 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-AA*
PKC-AA*
768 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-Ca-DAG
PKC-Ca-DAG
769 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG
PKC-DAG
770 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-DAG-AA
PKC-DAG-AA
771 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPKC-cytosolic
PKC-cytosolic
772 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secAA
AA
773 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-cytosolic
PLA2-cytosolic
774 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2-Ca*
PLA2-Ca*
775 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-PLA2*
PIP2-PLA2*
776 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPIP2-Ca-PLA2*
PIP2-Ca-PLA2*
777 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secDAG-Ca-PLA2*
DAG-Ca-PLA2*
778 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*-Ca
PLA2*-Ca
779 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPLA2*
PLA2*
780 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK
MAPK
781 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK-tyr
MAPK-tyr
782 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secinact-GEF
inact-GEF
783 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGEF*
GEF*
784 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP*
GAP*
785 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secGAP
GAP
786 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-GEF
CaM-GEF
787 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMAPK*
MAPK*
788 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secMKP-1
MKP-1
789 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secPPhosphatase2A
PPhosphatase2A
790 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM
CaM
791 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca3
CaM-Ca3
792 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-TR2-Ca2
CaM-TR2-Ca2
793 diff0.001
(s^-1)		0.001
(s^-1)		Keq = 1(uM)500secCaM-Ca4
CaM-Ca4
794 Ras-act-craf9.9998
(uM^-1 s^-1)		0.5
(s^-1)		Kd(bf) = 0.05(uM)-craf-1*
GTP-Ras
Raf*-GTP-Ras
  Assume the binding is fast and limited only by the amount of Ras* available. So kf=kb/[craf-1] If kb is 1/sec, then kf = 1/0.2 uM = 1/(0.2 * 6e5) = 8.3e-6 Later: Raise it by 10 X to 4e-5 From Hallberg et al JBC 269:6 3913-3916 1994, 3% of cellular Raf is complexed with Ras. So we raise kb 4x to 4 This step needed to memb-anchor and activate Raf: Leevers et al Nature 369 411-414 May 16, 2003 Changed Ras and Raf to synaptic levels, an increase of about 2x for each. To maintain the percentage of complexed Raf, reduced the kf by 2.4 fold to 10.
795 Ras-act-unphosph
-raf		6
(uM^-1 s^-1)		1
(s^-1)		Kd(bf) = 0.1667(uM)-craf-1
GTP-Ras
Raf-GTP-Ras
  18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.


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