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Result: 1 - 9 of 9 rows are displayed

Enzyme List for pathway PP1 (Pathway Number 247) in Accession AMPAR_traff_model1 (Accession Number 60)

Entries are grouped according to Pathway Number and they are alternately color coded using  and   color.
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  Enzyme Molecule /

 Enzyme Activity
Pathway Name / 
Pathway No.
Km
(uM)
kcat
(s^-1)
Ratio
(k2/k3)
Enzyme TypeReagents
1 PP2A /
  • PP2A-dephosph-I1
  • PP1

    Pathway No. 247
    15.999924.1667explicit E-S complexSubstrate: 
    I1*
    Product : 
    I1
      PP2A does most of the dephosph of I1 at basal Ca levels. See the review by Cohen in Ann Rev Biochem 1989. For now, lets halve Km. k1 was 3.3e-6, now 6.6e-6
    2 PP2A /
  • PP2A-dephosph-PP
    1-I*
  • PP1

    Pathway No. 247
    15.999924.1667explicit E-S complexSubstrate: 
    PP1-I1*
    Product : 
    PP1-I1
      k1 changed from 3.3e-6 to 6.6e-6
    3 PP2A /

  • PP2A-dephosph-I1
    _
    PSD
  • PP1

    Pathway No. 247
    15.999924.1667explicit E-S complexSubstrate: 
    I1*
    Product : 
    I1
      PP2A does most of the dephosph of I1 at basal Ca levels. See the review by Cohen in Ann Rev Biochem 1989. For now, lets halve Km. k1 was 3.3e-6, now 6.6e-6
    4 PP2A /

  • PP2A-dephosph-PP
    1-I*_
    PSD
  • PP1

    Pathway No. 247
    15.999924.1667explicit E-S complexSubstrate: 
    PP1-I1*
    Product : 
    PP1-I1
      k1 changed from 3.3e-6 to 6.6e-6
    5 PP1-active /
    Deph-thr286
    PP1

    Pathway No. 247
    5.099052.54explicit E-S complexSubstrate: 
    CaMKII-thr286*-C
    aM

    Product : 
    CaMKII-CaM
    6 PP1-active /
    Deph-thr286b
    PP1

    Pathway No. 247
    5.099052.54explicit E-S complexSubstrate: 
    CaMKII-thr286
    Product : 
    CaMKII
    7 PP1-active /
    Deph-thr305
    PP1

    Pathway No. 247
    5.099052.54explicit E-S complexSubstrate: 
    CaMKII***
    Product : 
    CaMKII-thr286
    8 PP1-active /
    Deph-thr286c
    PP1

    Pathway No. 247
    5.099052.54explicit E-S complexSubstrate: 
    CaMKII***
    Product : 
    CaMK-thr305
    9 PP1-active /
    Deph-thr305a
    PP1

    Pathway No. 247
    5.099052.54explicit E-S complexSubstrate: 
    CaMK-thr305
    Product : 
    CaMKII

     
    Result: 1 - 9 of 9 rows are displayed



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