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Result: 1 - 11 of 11 rows are displayed

Molecule List for pathway CaMKII (Pathway Number 174) in Accession CaMKII (Accession Number 33)

Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.
arrow indicates that ordering is done according to ascending or descending order.
The entries are grouped according to Pathway Number and are alternately color coded using  and  color.
  NameAccession
Type
Initial
Conc.

(uM)
Volume
(fL)
BufferedSum Total Of
1 AutonomousNetwork00.1309No
2 CaMKIINetwork12.73250.1309No
    Init level is 100 holoenzymes of 10 subunits each.
3 CaMKII-CaMNetwork00.1309No
4 CAMKII-CaMCaNetwork00.1309No
5 CaMKII-CaMCa2Network00.1309No
6 CaMKII-CaMCa3Network00.1309No
7 CaMKII-CaMCa4Network00.1309No
8 CappedNetwork00.1309No
9 
  • Tot-active-CaMKI
    I
  • Network00.1309No CaMKII-CaMCa4
     Trapped-T286
     Capped
     Autonomous
    10 Total_CaMKIINetwork127.3250.1309No
        This is not directly in the Holmes model. It is a trick used in GENESIS/Kinetikit to scale activity down for intramolecular reactions. Here it is used to scale the autophosph reactions such that only neighboring subunits will phosphorylate each other. This is done by scaling down the actual conc (in the enzyme parent, Tot-active-CaMKII) by the total conc such that instead of a conc, we the fraction of nearby subunits that will be active. Note that this conc of 10000 CaMKII subunits is 10 times the true conc, since only 1/10 of the molecules are neighboring molecules.
    11 Trapped-T286Network00.1309No

     
    Result: 1 - 11 of 11 rows are displayed



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