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Result: 1 - 4 of 4 rows are displayed

Molecule List for pathway PP1 (Pathway Number 266) in Accession CaMKII_model3 (Accession Number 63)

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The entries are grouped according to Pathway Number and are alternately color coded using  and  color.

BufferedSum Total Of
1 I1Network1.80.09No
    I1 is a 'mixed' inhibitor, but at high enz concs it looks like a non-compet inhibitor (Foulkes et al Eur J Biochem 132 309-313 9183). We treat it as non-compet, so it just turns the enz off without interacting with the binding site. Cohen et al ann rev bioch refer to results where conc is 1.5 to 1.8 uM. In order to get complete inhib of PP1, which is at 1.8 uM, we need >= 1.8 uM.
2 I1*Network00.09No
    Dephosph is mainly by PP2B
3 PP1-I1Network00.09No
4 PP1-I1*Network00.09No

Result: 1 - 4 of 4 rows are displayed

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