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Accession Type:
Network
NonOsc_Ca_
IP3metabolism
MIPP
CaMKII
CaM
PKC
IP3-3K
CaRegulation
Gq
 Molecule
 Reaction
PLCbeta
134_dephos
145_dephos
IP4-system
IHP-system
1345_dephos

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Parameters for Gq (Pathway Number 111)

Pathway Layout

Pathway Basic Parameters

Pathway NameGq
Pathway Entry Number 111
Accession Number 23
Accession Name NonOsc_Ca_IP3metabolism
Species Generic mammalian
Tissue Brain - Neuronal
CellCompartmentCytosol
Related Pathways 5, 23, 74, 125, 150, 163, 210, 316, 334, 351
Notes The model for the Gq pathway plus its activators, here represented by the metabotropic glutamate receptor. We assume GTP is present in fixed amounts, so we leave it out of the explicit equations in this model. Normally we would expect it to associate along with the G-Receptor-ligand complex. Most info is from Berstein G et al J Biol Chem. 1992 Apr 25;267(12):8081-8. Structure of receptor activation of Gq from Fay SP et al Biochemistry. 1991 May 21;30(20):5066-75.This mGluR/Gq model lacks a mechanism for receptor desensitization.

Statistics

Enzyme sites
11
0
9

Conversion format

This pathway is part of accession 23 and is completely specified in the file acc23.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc23.g   
GENESIS Format (Annotated version)    Anno_acc23.g   


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Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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